Page last updated: 2024-08-22

trimetazidine and Cardiomyopathies, Primary

trimetazidine has been researched along with Cardiomyopathies, Primary in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (22.73)18.2507
2000's6 (27.27)29.6817
2010's6 (27.27)24.3611
2020's5 (22.73)2.80

Authors

AuthorsStudies
Guieu, R; Maixent, JM; Paganelli, F; Pierre, SV; Sadrin, S1
Chen, B; Dai, C; Li, J; Li, Y; Qi, Y; Wang, J1
El-Khodary, NM; El-Tayaar, AA; El-Touny, EM; Ghoneim, AI1
Chen, X; Dong, T; Du, L; Lin, Z; Xia, X; Zhou, H1
Eid, BG; El-Shitany, NAE; Neamatallah, T1
Fan, Q; Ma, L; Niu, Z1
Kavtaradze, N; Saganelidze, K1
Amin, MR; Arzu, J; Banerjee, RS; Ear-E-Mahabub, SM; Hoque, MH; Joarder, AI; Kabir, FI; Singha, CK; Zaman, SM1
Handzlik-Orlik, G; Krysiak, R; Okopień, B; Sarnecki, K; Stadnik, M1
Beker, DL; Fillmore, N; Jaswal, JS; Keung, W; Lopaschuk, GD; Mori, J; Ussher, JR; Wagg, CS1
Belardinelli, R; Cianci, G; Gigli, M; Lacalaprice, F; Mazzanti, M1
Belardinelli, R; Faccenda, E; Lacalaprice, F; Volpe, L1
Chen, J; Li, C; Xu, W; Zhou, X1
Abdel-Hady, S; El-Kady, T; El-Sabban, K; Gabaly, M; Sabry, A1
Chen, XJ; Feng, L; Meng, D; Yang, D; Zhang, JN1
Barkhudarian, AL; Sisakian, AS; Torgomian, AL1
Adachi, N; Hayashi, K; Himei, H; Kondo, A; Matsuki, T; Matsuoka, T1
Pogátsa, G1
D'hahan, N; Janmot, C; Morel, JE; Taouil, K1
Belardinelli, R; Purcaro, A1
Boucher, F; de Leiris, J1
Barat, JL; Bonnet, J; Boussens, B; Bricaud, H; Brottier, L; Combe, C1

Reviews

5 review(s) available for trimetazidine and Cardiomyopathies, Primary

ArticleYear
Meta-analysis of trimetazidine treatment for cardiomyopathy.
    Bioscience reports, 2018, 06-29, Volume: 38, Issue:3

    Topics: Aged; Cardiomyopathies; Cardiotonic Agents; Echocardiography; Female; Heart Function Tests; Humans; Male; Middle Aged; Treatment Outcome; Trimetazidine; Vasodilator Agents

2018
[MODERN ASPECTS OF DIAGNOSIS AND TREATMENT OF HEART FAILURE, AS A MANIFESTATION OF ANTHRACYCLINE CARDIOTOXICITY (REVIEW)].
    Georgian medical news, 2018, Issue:278

    Topics: Anthracyclines; Antineoplastic Agents; Biomarkers; Cardiomyopathies; Cardiotonic Agents; Cardiotoxicity; Echocardiography; Elapid Venoms; Heart; Heart Failure; Humans; Ivabradine; Natriuretic Peptide, C-Type; Neoplasms; Survival Analysis; Trastuzumab; Trimetazidine; Troponin I

2018
[Clinical aspects of the use of trimetazidine in the prevention and treatment of myocardial diseases].
    Przeglad lekarski, 2013, Volume: 70, Issue:9

    Topics: Acidosis; Blood Glucose; Cardiomyopathies; Cardiotonic Agents; Diabetes Complications; Fatty Acids; Humans; Myocardium; Oxidation-Reduction; Trimetazidine

2013
[New concepts in the therapy of diabetic cardiopathies].
    Orvosi hetilap, 1997, Jun-08, Volume: 138, Issue:23

    Topics: Adenosine Triphosphate; Cardiomyopathies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Trimetazidine

1997
Ischemic myocardial cell necrosis: calcium overload or oxygen free-radicals?
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1990, Volume: 9, Issue:2

    Topics: Calcium; Cardiomyopathies; Coronary Disease; Free Radicals; Humans; Myocardial Reperfusion; Necrosis; Oxygen; Time Factors; Trimetazidine

1990

Trials

9 trial(s) available for trimetazidine and Cardiomyopathies, Primary

ArticleYear
The Impact of Trimetazidine on Cardiac Fibrosis, Inflammation, and Function in Ischemic Cardiomyopathy Patients.
    Cardiovascular drugs and therapy, 2023, Volume: 37, Issue:5

    Topics: Angina Pectoris; Cardiomyopathies; Fibrosis; Humans; Inflammation; Myocardial Ischemia; Trimetazidine; Tumor Necrosis Factor-alpha; Vasodilator Agents

2023
Comparison between Glyceryl Trinitrate and Trimetazidine in Ischaemic Cardiomyopathy Patients.
    Mymensingh medical journal : MMJ, 2019, Volume: 28, Issue:1

    Topics: Bangladesh; Cardiomyopathies; Humans; Male; Myocardial Contraction; Myocardial Ischemia; Nitroglycerin; Pilot Projects; Prospective Studies; Treatment Outcome; Trimetazidine; Vasodilator Agents

2019
Effects of trimetazidine on myocardial perfusion and left ventricular systolic function in type 2 diabetic patients with ischemic cardiomyopathy.
    Journal of cardiovascular pharmacology, 2008, Volume: 51, Issue:6

    Topics: Cardiomyopathies; Coronary Circulation; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Systole; Trimetazidine; Vasodilator Agents; Ventricular Function, Left

2008
Trimetazidine potentiates the effects of exercise training in patients with ischemic cardiomyopathy referred for cardiac rehabilitation.
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2008, Volume: 15, Issue:5

    Topics: Aged; Biomarkers; Blood Pressure; Body Mass Index; Brachial Artery; Cardiomyopathies; Combined Modality Therapy; Echocardiography, Doppler, Pulsed; Electrocardiography; Exercise Test; Exercise Therapy; Female; Humans; Longitudinal Studies; Male; Middle Aged; Myocardial Ischemia; Oxygen Consumption; Stroke Volume; Time Factors; Treatment Outcome; Trimetazidine; Vasodilation; Vasodilator Agents; Ventricular Dysfunction, Left

2008
Effects of trimetazidine on myocardial perfusion and the contractile response of chronically dysfunctional myocardium in ischemic cardiomyopathy: a 24-month study.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2005, Volume: 5, Issue:4

    Topics: Aged; Cardiomyopathies; Coronary Circulation; Echocardiography; Exercise Test; Female; Heart Function Tests; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon; Trimetazidine; Vasodilator Agents

2005
[The effects of trimetazidine on left ventricular function and physical exercise tolerance in patients with ischemic cardiomyopathy].
    Klinicheskaia meditsina, 2006, Volume: 84, Issue:10

    Topics: Aged; Cardiomyopathies; Exercise; Exercise Tolerance; Female; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Ischemia; Trimetazidine; Vasodilator Agents

2006
[Cardiac impairment of elderly patients with diabetes mellitus as studied with non-invasive myocardial scintigraphy and signal-averaged electrocardiography].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1996, Volume: 33, Issue:6

    Topics: 3-Iodobenzylguanidine; Aged; Cardiomyopathies; Diabetes Complications; Electrocardiography; Heart; Humans; Iodine Radioisotopes; Iodobenzenes; Middle Aged; Tomography, Emission-Computed, Single-Photon; Trimetazidine; Vasodilator Agents

1996
Effects of trimetazidine on the contractile response of chronically dysfunctional myocardium to low-dose dobutamine in ischaemic cardiomyopathy.
    European heart journal, 2001, Volume: 22, Issue:23

    Topics: Analysis of Variance; Cardiomyopathies; Double-Blind Method; Female; Humans; Male; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Trimetazidine; Vasodilator Agents; Ventricular Dysfunction, Left

2001
Therapeutic value of a cardioprotective agent in patients with severe ischaemic cardiomyopathy.
    European heart journal, 1990, Volume: 11, Issue:3

    Topics: Angina Pectoris; Cardiomyopathies; Coronary Disease; Double-Blind Method; Drug Evaluation; Female; Hemodynamics; Humans; Male; Middle Aged; Piperazines; Trimetazidine

1990

Other Studies

8 other study(ies) available for trimetazidine and Cardiomyopathies, Primary

ArticleYear
Effects of long-term anti-ischemic drug treatment on Na,K-ATPase isoforms in cardiomyopathic hamsters.
    Cellular and molecular biology (Noisy-le-Grand, France), 2021, Aug-31, Volume: 67, Issue:2

    Topics: Animals; Blotting, Western; Cardiomyopathies; Cricetinae; Heart; Ischemia; Isoenzymes; Male; Mesocricetus; Myocardium; Sodium-Potassium-Exchanging ATPase; Time Factors; Trimetazidine; Vasodilator Agents; Ventricular Remodeling

2021
Trimetazidine Alleviates Postresuscitation Myocardial Dysfunction and Improves 96-Hour Survival in a Ventricular Fibrillation Rat Model.
    Journal of the American Heart Association, 2022, 03-15, Volume: 11, Issue:6

    Topics: Animals; Biomarkers; Cardiomyopathies; Cardiopulmonary Resuscitation; Inflammation; Rats; Rats, Sprague-Dawley; Stroke Volume; Trimetazidine; Ventricular Fibrillation; Ventricular Function, Left

2022
Trimetazidine Reduces Cardiac Fibrosis in Rats by Inhibiting NOX2-Mediated Endothelial-to-Mesenchymal Transition.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Animals; Cardiomyopathies; Epithelial-Mesenchymal Transition; Fibrosis; Human Umbilical Vein Endothelial Cells; Humans; NF-kappa B; Rats; Rats, Sprague-Dawley; Stroke Volume; Transforming Growth Factor beta; Trimetazidine; Ventricular Function, Left

2022
Trimetazidine improved adriamycin-induced cardiomyopathy by downregulating TNF-α, BAX, and VEGF immunoexpression via an antioxidant mechanism.
    Environmental toxicology, 2021, Volume: 36, Issue:6

    Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Cardiomyopathies; Doxorubicin; Oxidative Stress; Rats; Rats, Wistar; Trimetazidine; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2021
Trimetazidine therapy prevents obesity-induced cardiomyopathy in mice.
    The Canadian journal of cardiology, 2014, Volume: 30, Issue:8

    Topics: Acetyl-CoA C-Acyltransferase; Animals; Cardiomyopathies; Echocardiography; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Obesity; Oxidation-Reduction; Palmitates; Trimetazidine; Vasodilator Agents

2014
Trimetazidine protects against smoking-induced left ventricular remodeling via attenuating oxidative stress, apoptosis, and inflammation.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Animals; Apoptosis; Cardiomyopathies; Cardiotonic Agents; Cytokines; Drug Evaluation, Preclinical; Gene Expression Regulation; Inflammation; Inflammation Mediators; Male; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Wistar; Smoking; Trimetazidine; Vasodilator Agents; Ventricular Remodeling

2012
Trimetazidine improved Ca2+ handling in isoprenaline-mediated myocardial injury of rats.
    Experimental physiology, 2006, Volume: 91, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cardiomyopathies; Cardiotonic Agents; Disease Models, Animal; Drug Combinations; Isoproterenol; Male; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Treatment Outcome; Trimetazidine; Vasodilator Agents

2006
Effect of trimetazidine and verapamil on the cardiomyopathic hamster myosin phenotype.
    British journal of pharmacology, 1998, Volume: 123, Issue:4

    Topics: Animals; Calcium Channel Blockers; Calcium-Transporting ATPases; Cardiomyopathies; Cricetinae; Electrophoresis, Polyacrylamide Gel; Mesocricetus; Myosins; Phenotype; Trimetazidine; Vasodilator Agents; Verapamil

1998