Page last updated: 2024-08-22

trimetazidine and Angor Pectoris

trimetazidine has been researched along with Angor Pectoris in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-19906 (5.26)18.7374
1990's22 (19.30)18.2507
2000's57 (50.00)29.6817
2010's20 (17.54)24.3611
2020's9 (7.89)2.80

Authors

AuthorsStudies
Joshi, SR; Nair, T1
Li, N; Liu, J; Qiu, L; Shen, L; Shu, H; Zhou, N1
El-Khodary, NM; El-Tayaar, AA; El-Touny, EM; Ghoneim, AI1
Cesar, LAM; Dourado, LOC; Gowdak, LHW; Grobe, SF; Moreno, CPD1
Arumugham, SS; Ashton, M; Berk, M; Colomer, L; Das, B; Dean, OM; Debnath, M; Giménez-Palomo, A; Goyal, N; Kesavan, M; Khanra, S; Kim, JH; McCallum, M; Pacchiarotti, I; Panizzutti, B; Park, CHJ; Reddy, P; Reddy, YCJ; Turner, A; Umesh, S; Venkatasubramanian, G; Vieta, E; Walder, K; Yatham, LN1
Chang, J; Choi, HY; Hong, SP; Jin, ES; Kong, MG; Kwon, SS; Park, GM; Park, RW; Park, S1
Thadani, U2
Al-Amran, F; Al-Aubaid, H; Fatima, G; Hadi, NR; Shaker, SR1
Robson, A1
Ciapponi, A; Harrison, J; Pizarro, R2
Kaski, JC; Tarkin, JM1
Caetano, PA; Heleno, B; Pinto, D; Rodrigues, DS; Santos, I; Silva, A1
Challeton, JP; Danchin, N; Ferrari, R; Ford, I; Fox, K; Marzilli, M; Tendera, M; Widimský, P1
Jones, DA; Timmis, A; Wragg, A1
Gao, F; Liu, Y; Ma, H; Ma, Q; Shen, H; Shi, D; Wang, Z; Xu, X; Yu, M; Zhang, J; Zhang, W; Zhao, Y; Zhou, Y; Zhou, Z1
Fillmore, N; Ilkayeva, OR; Jaswal, JS; Keung, W; Koves, TR; Lopaschuk, DG; Lopaschuk, GD; Mori, J; Muoio, DM; Ussher, JR; Wagg, CS; Zhang, L1
Fang, D; Fang, Q; Li, K; Peng, S; Wan, J; Zhao, M1
Fi, Z; Kovács, G; Szentes, V1
Ma, XJ; Shi, DZ; Zhang, Y1
Colombo, A; Fragasso, G; Fumero, A; Giannini, F; Godino, C; Maranta, F; Margonato, A; Oppizzi, M; Slavich, M1
Kerins, DM; McCarthy, CP; Mullins, KV1
Glezer, M1
Glezer M, G; On Behalf Of The Choice-Study Participants, OB1
Białoszyński, T; Grabczewska, Z; Grześk, G; Kochman, W; Koziński, M; Kubica, J; Sukiennik, A; Swiatkiewicz, I; Szymański, P1
Arora, R; Jawad, E1
Banach, M; Goch, A; Mikhailidis, DP; Rosano, GM; Rysz, J1
Kulikov, KG; Shal'nova, SA; Shkol'nik, EL; Vasiuk, IuA2
César, LA; Gowdak, LH; Mansur, AP1
Barone, L; Crea, F; Di Monaco, A; Lamendola, P; Lanza, GA; Pisanello, C1
Kudriakov, ON; Kulikov, KG; Shkol'nik, EL; Vasiuk, YA1
Antony, R; Dargie, HJ1
Chen, YD; Du, ZM; Jiang, H; Tian, F; Wei, M; Zhao, LK1
Chen, T; Guo, J; Hu, B; Li, W; Xu, T1
Simonenko, VB; Stepaniants, OS; Teslia, AN1
Bochkareva, EV; Butina, EK; Dmitrieva, NA; Kokurina, EV1
Maisch, B; Rupp, H; Zarain-Herzberg, A1
Fitilev, SB; Ivanova, EV; Lepakhin, VK; Levin, AM; Syrkin, AL; Titarova, IuIu1
Koziolova, NA1
Klein, WW; Marzilli, M1
Manchanda, SC1
Marzilli, M; Stanley, WC1
Artiukhina, EG; Chuntyzheva, MM; Kanorskiĭ, SG; Syrkin, AL1
Altinbas, A; Dogan, A; Ergene, O; Gedikli, O; Ozaydin, M1
Makolkin, VI; Osadchiĭ, KK1
Bada, V; Kölbel, F1
Almazov, VV; Kazarin, VV; Nifontov, EM; Rudomanov, OG; Shlyakhto, EV; Vakhrameyeva, IV; Vakhrameyeva, NV; Zakharov, DV1
Broustet, JP; Sellier, P1
Frenneaux, M; Horowitz, J; Lee, L1
Szwed, H2
Elikowski, W; Grzelak-Szafranska, H; Orszulak, W; Ruzyllo, W; Sadowski, Z; Szwed, H; Szymczak, K; Winter, M1
Lupanov, VP; Matveeva, MA; Mironova, IIu; Naumov, VG; Orlova, EM; Samoĭlenko, LE1
Adalet, K; Bilge, AK; Büyüköztürk, K; Koylan, N; Mercanoglu, F1
Bakhmatova, IuA; Gapon, LI; Kalinina, VA; Kuznetsov, VA; Petelina, TI; Todosiĭchuk, VV; Zhevagina, IA1
Gupta, R; Narain, VS; Sawhney, JP1
McCullough, PA1
Inglis, S; Stewart, S1
Meluzín, J1
Kölbel, F1
Chaloupka, V1
Danchin, N1
Amabile, N; Bonello, L; Com, O; Levy, S; Paganelli, F; Pierre, SV; Sbragia, P1
Baiandin, NL; Gordeev, IG; Il'ina, EE; Kuznechevskiĭ, FV; Liusov, VA1
Armaganijan, D; Bicudo, L; Brasil, CK; Cesar, LA; Del Monaco, MI; Gimenez, V; Gomes, EP; Jallad, S; Mathias, W; Meneguin, S; Ramires, JF1
Deev, AD; Glezer, MG; Oganov, RG1
Leitão, C; Polanczyk, CA; Ribeiro, JP; Ribeiro, LW; Stein, R1
Chaitman, BR; Sano, J1
Lévy, S2
Detry, JM; Leclercq, PJ1
Ribeiro, C1
Detry, JM1
Chierchia, SL; Fragasso, G1
Cokkinos, D; Dargie, H; Detry, JM; Mathes, P; Pennaforte, S; Sellier, P1
Coker, S; Détry, JM; Harpey, C; Maccario, J; Sellier, P1
Akimova, OS; Tereshchenko, SN; Tertychnaia, GF1
Krishnaswami, S; Manchanda, SC1
Jackson, G3
Allal, J; Harpey, C; Ourbak, P; Pornin, M; Sellier, P1
McClellan, KJ; Plosker, GL1
Akhmetov, KZh; Goncharov, LF; Goncharova, ZF; Kelimberdieva, ES; Komissarova, IA; Teĭblium, MM; Zaslavskaia, RM1
Kalinina, EV; Kelimberdieva, ES; Komissarova, IA; Novichkova, MD; Zaslavskaia, RM1
Kantor, PF; Kozak, R; Lopaschuk, GD; Lucien, A1
Domzal-Bochenska, M; Elikowski, W; Gajos, G; Kaluza, G; Kulon, I; Kuźniak, M; Pachocki, R; Paradowski, A; Szwed, H; Szydlowski, Z; Szymczak, K; Wator-Brzezińska, A1
Dzhanashiia, PKh; Glazunov, AV; Sorokoletov, SM; Urzhumova, TV; Zhiliaev, EV1
Baj, Z; Kowalski, J; Olejniczak, J; Paśnik, J; Pawlicki, L1
Kolycheva, SV; Lankin, VZ; Tikhaze, AK; Zharova, EA1
Hradec, J; Préda, I; Szwed, H1
Pogatsa, G1
Chernov, MIu; Chernov, SA; Davydova, TV; Korneev, NV; Kutepov, IuS; Makarenkova, LA; Sharonova, SP; Spicheva, IA; Tiurin, VP; Virs, EA1
Cross, HR1
Elikowski, W; Koronkiewicz, A; Mamcarz, A; Orszulak, W; Sadowski, Z; Skibińska, E; Swiatek, J; Szwed, H; Szymczak, K; Winter, M1
Auteri, A; Blardi, P; de Lalla, A; Di Perri, T; Volpi, L1
Stanley, WC1
Durr, F; Faucon, G; Harpey, C; Timour, Q1
Audouin, P; Corona, P; Harpey, C; Ourbak, P; Sellier, P1
Sellier, P2
Brochier, M; Demange, J; Ducloux, G; Monpère, C; Warin, JF1
Berckmans, T; Detry, JM; Fesler, R; Leclercq, P1
Dalla-Volta, S; Della-Valentina, P; Desideri, A; Maraglino, G; Viena, P1
Ayudhya, RK; Jintapakorn, W; Suntiparpluacha, C; Yipintsoi, S; Yipintsoi, T1
Barat, JL; Bonnet, J; Boussens, B; Bricaud, H; Brottier, L; Combe, C1
Audouin, P; Duong, TC; Ourbak, P; Payen, B; Sellier, P1
Passeron, J1
Gallet, M2
Audouin, P; Corona, P; Duong, TC; Ourbak, P; Payen, B; Sellier, P1

Reviews

31 review(s) available for trimetazidine and Angor Pectoris

ArticleYear
Metabolic regulation to treat bipolar depression: mechanisms and targeting by trimetazidine.
    Molecular psychiatry, 2023, Volume: 28, Issue:8

    Topics: Angina Pectoris; Antioxidants; Bipolar Disorder; Humans; Trimetazidine; Vasodilator Agents

2023
WITHDRAWN: Trimetazidine for stable angina.
    The Cochrane database of systematic reviews, 2017, 03-20, Volume: 3

    Topics: Adult; Angina Pectoris; Humans; Randomized Controlled Trials as Topic; Trimetazidine; Vasodilator Agents

2017
Novel drugs for treating angina.
    BMJ (Clinical research ed.), 2013, Sep-09, Volume: 347

    Topics: Acetanilides; Angina Pectoris; Benzazepines; Enzyme Inhibitors; Heart Rate; Humans; Ivabradine; Nicorandil; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents

2013
The efficacy of trimetazidine on stable angina pectoris: a meta-analysis of randomized clinical trials.
    International journal of cardiology, 2014, Dec-20, Volume: 177, Issue:3

    Topics: Angina Pectoris; Humans; Randomized Controlled Trials as Topic; Treatment Outcome; Trimetazidine; Vasodilator Agents

2014
[Role of trimetazidine in the treatment of diabetic microangiopathy in ischaemic heart disease].
    Orvosi hetilap, 2015, May-10, Volume: 156, Issue:19

    Topics: Angina Pectoris; Anti-Inflammatory Agents, Non-Steroidal; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Heart; Humans; Myocardial Infarction; Myocardial Ischemia; Myocardium; Trimetazidine; Vasodilator Agents

2015
Effect of Trimetazidine in Patients Undergoing Percutaneous Coronary Intervention: A Meta-Analysis.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Angina Pectoris; Female; Humans; Male; Models, Biological; Myocardium; Natriuretic Peptide, Brain; Percutaneous Coronary Intervention; Stroke Volume; Trimetazidine; Troponin I; Ultrasonography

2015
The role of trimetazidine in cardiovascular disease: beyond an anti-anginal agent.
    European heart journal. Cardiovascular pharmacotherapy, 2016, Volume: 2, Issue:4

    Topics: Angina Pectoris; Animals; Humans; Trimetazidine; Vasodilator Agents

2016
Chronic stable angina pectoris.
    Disease-a-month : DM, 2008, Volume: 54, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetanilides; Angina Pectoris; Antihypertensive Agents; Benzazepines; Bosentan; Chronic Disease; Counterpulsation; Cyclic Nucleotide-Gated Cation Channels; Exercise Test; Heart Murmurs; Humans; Ivabradine; Myocardial Contraction; Myocardial Ischemia; Myocardial Revascularization; Myocardium; Nicorandil; Oxygen Consumption; Perhexiline; Piperazines; Protein Kinase Inhibitors; Ranolazine; Sulfonamides; Trimetazidine; Vasodilator Agents

2008
The role of trimetazidine after acute myocardial infarction.
    Current vascular pharmacology, 2008, Volume: 6, Issue:4

    Topics: Acute Coronary Syndrome; Angina Pectoris; Cardiovascular Agents; Energy Metabolism; Humans; Myocardial Infarction; Myocardium; Practice Guidelines as Topic; Treatment Outcome; Trimetazidine

2008
The metabolic treatment of patients with coronary artery disease: effects on quality of life and effort angina.
    Current pharmaceutical design, 2009, Volume: 15, Issue:8

    Topics: Acetanilides; Angina Pectoris; Animals; Carnitine; Clinical Trials as Topic; Coronary Artery Disease; Dichloroacetic Acid; Humans; Piperazines; Quality of Life; Ranolazine; Ribose; Surveys and Questionnaires; Trimetazidine; Vasodilator Agents

2009
[Mechanisms of myocardial cell protection from ischemia/reperfusion injury and potential clinical implications].
    Giornale italiano di cardiologia (2006), 2009, Volume: 10, Issue:1

    Topics: Acetanilides; Acute Coronary Syndrome; Angina Pectoris; Animals; Apoptosis; Cell Death; Collateral Circulation; Disease Models, Animal; Humans; Ischemic Preconditioning, Myocardial; Meta-Analysis as Topic; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Oxygen Consumption; Piperazines; Randomized Controlled Trials as Topic; Ranolazine; Trimetazidine; Vasodilator Agents

2009
[Effect of therapy with trimetazidine modified release on quality of life of patients with stable effort angina survivors after acute myocardial infarction. Results of PRIMA study].
    Kardiologiia, 2010, Volume: 50, Issue:4

    Topics: Angina Pectoris; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Myocardial Infarction; Quality of Life; Treatment Outcome; Trimetazidine; Vasodilator Agents

2010
Evaluation of trimetazidine in angina pectoris by echocardiography and radionuclide angiography: a meta-analysis of randomized, controlled trials.
    Clinical cardiology, 2011, Volume: 34, Issue:6

    Topics: Aged; Angina Pectoris; Drug Therapy, Combination; Echocardiography; Evidence-Based Medicine; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Radionuclide Angiography; Randomized Controlled Trials as Topic; Stroke Volume; Time Factors; Treatment Outcome; Trimetazidine; Vasodilator Agents; Ventricular Function, Left

2011
The use of partial fatty acid oxidation inhibitors for metabolic therapy of angina pectoris and heart failure.
    Herz, 2002, Volume: 27, Issue:7

    Topics: Acetanilides; Angina Pectoris; Animals; Calcium; Cardiovascular Agents; Clinical Trials as Topic; Enzyme Inhibitors; Epoxy Compounds; Fatty Acids; Gene Expression; Glucose; Heart Failure; Humans; Hypoglycemic Agents; Methylhydrazines; Myocytes, Cardiac; Oxidation-Reduction; Piperazines; Ranolazine; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Trimetazidine; Up-Regulation; Vasodilator Agents

2002
Efficacy and tolerability of trimetazidine in stable angina: a meta-analysis of randomized, double-blind, controlled trials.
    Coronary artery disease, 2003, Volume: 14, Issue:2

    Topics: Aged; Angina Pectoris; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Exercise Tolerance; Female; Humans; Male; Middle Aged; Nitroglycerin; Severity of Illness Index; Treatment Outcome; Trimetazidine; Vasodilator Agents

2003
Metabolic therapy in the treatment of ischaemic heart disease: the pharmacology of trimetazidine.
    Fundamental & clinical pharmacology, 2003, Volume: 17, Issue:2

    Topics: Angina Pectoris; Carbohydrate Metabolism; Diabetes Complications; Diabetes Mellitus; Energy Metabolism; Fatty Acids; Humans; Myocardial Ischemia; Myocardium; Trimetazidine; Vasodilator Agents; Ventricular Dysfunction, Left

2003
Metabolic manipulation in ischaemic heart disease, a novel approach to treatment.
    European heart journal, 2004, Volume: 25, Issue:8

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Cardiovascular Agents; Drug Therapy, Combination; Enzyme Inhibitors; Epoxy Compounds; Glucose; Humans; Hypoglycemic Agents; Insulin; Myocardial Ischemia; Myocardium; Perhexiline; Piperazines; Potassium; Ranolazine; Trimetazidine

2004
Clinical benefits of trimetazidine in patients with recurrent angina.
    Coronary artery disease, 2004, Volume: 15 Suppl 1

    Topics: Angina Pectoris; Humans; Myocardial Revascularization; Randomized Controlled Trials as Topic; Recurrence; Trimetazidine; Vasodilator Agents

2004
Chronic angina: new medical options for treatment.
    Reviews in cardiovascular medicine, 2005,Summer, Volume: 6, Issue:3

    Topics: Acetanilides; Angina Pectoris; Cardiovascular Agents; Chronic Disease; Enzyme Inhibitors; Humans; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents

2005
Trimetazidine for stable angina.
    The Cochrane database of systematic reviews, 2005, Oct-19, Issue:4

    Topics: Adult; Angina Pectoris; Humans; Randomized Controlled Trials as Topic; Trimetazidine; Vasodilator Agents

2005
Metabolic therapeutics in angina pectoris: history revisited with perhexiline.
    European journal of cardiovascular nursing, 2006, Volume: 5, Issue:2

    Topics: Acetanilides; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Agents; Carnitine O-Palmitoyltransferase; Drug Monitoring; Epoxy Compounds; Fatty Acids; Half-Life; Humans; Metabolic Clearance Rate; Nurse's Role; Nursing Assessment; Patient Education as Topic; Patient Selection; Perhexiline; Piperazines; Randomized Controlled Trials as Topic; Ranolazine; Treatment Outcome; Trimetazidine; Vasodilator Agents

2006
Clinical benefits of a metabolic approach with trimetazidine in revascularized patients with angina.
    The American journal of cardiology, 2006, Sep-04, Volume: 98, Issue:5A

    Topics: Angina Pectoris; Electrocardiography; Humans; Myocardial Revascularization; Postoperative Period; Treatment Outcome; Trimetazidine; Vasodilator Agents

2006
Novel therapeutic approaches to treating chronic angina in the setting of chronic ischemic heart disease.
    Clinical cardiology, 2007, Volume: 30, Issue:2 Suppl 1

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Calcium Channel Blockers; Chronic Disease; Enzyme Inhibitors; Humans; Ivabradine; Myocardial Ischemia; Nicorandil; Nitro Compounds; Piperazines; Ranolazine; rho-Associated Kinases; Sinoatrial Node; Trimetazidine; Vasodilator Agents

2007
Clinical features of an anti-anginal drug in angina pectoris.
    European heart journal, 1993, Volume: 14 Suppl G

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Male; Middle Aged; Nifedipine; Trimetazidine

1993
Metabolic management of ischaemic heart disease.
    European heart journal, 1993, Volume: 14 Suppl G

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Carnitine; Energy Metabolism; Humans; Myocardium; Nitroglycerin; Piperazines; Ranolazine; Trimetazidine

1993
Trimetazidine. A review of its use in stable angina pectoris and other coronary conditions.
    Drugs, 1999, Volume: 58, Issue:1

    Topics: Angina Pectoris; Animals; Coronary Disease; Humans; Trimetazidine; Vasodilator Agents

1999
Anti-ischaemic efficacy and tolerability of trimetazidine administered to patients with angina pectoris: results of three studies.
    Coronary artery disease, 2001, Volume: 12 Suppl 1

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Drug Tolerance; Exercise Test; Exercise Tolerance; Humans; Metoprolol; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Trimetazidine; Vasodilator Agents

2001
Metabolic energy metabolism in diabetes: therapeutic implications.
    Coronary artery disease, 2001, Volume: 12 Suppl 1

    Topics: Angina Pectoris; Animals; Circadian Rhythm; Diabetic Angiopathies; Energy Metabolism; Glycolysis; Humans; Myocardial Reperfusion; Myocardium; Trimetazidine; Vasodilator Agents

2001
Trimetazidine for stable angina pectoris.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:5

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angioplasty, Balloon, Coronary; Animals; Calcium Channel Blockers; Coronary Artery Bypass; Exercise Test; Humans; Nitroglycerin; Trimetazidine; Vasodilator Agents; Ventricular Function, Left

2001
Combination therapy in angina: a review of combined haemodynamic treatment and the role for combined haemodynamic and cardiac metabolic agents.
    International journal of clinical practice, 2001, Volume: 55, Issue:4

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Nitrates; Treatment Outcome; Trimetazidine; Vasodilator Agents

2001
Partial fatty acid oxidation inhibitors for stable angina.
    Expert opinion on investigational drugs, 2002, Volume: 11, Issue:5

    Topics: Acetanilides; Adenosine Triphosphate; Angina Pectoris; Chronic Disease; Energy Metabolism; Fatty Acids; Humans; Myocardium; Oxidation-Reduction; Oxygen Consumption; Piperazines; Ranolazine; Trimetazidine

2002

Trials

52 trial(s) available for trimetazidine and Angor Pectoris

ArticleYear
The Impact of Trimetazidine on Cardiac Fibrosis, Inflammation, and Function in Ischemic Cardiomyopathy Patients.
    Cardiovascular drugs and therapy, 2023, Volume: 37, Issue:5

    Topics: Angina Pectoris; Cardiomyopathies; Fibrosis; Humans; Inflammation; Myocardial Ischemia; Trimetazidine; Tumor Necrosis Factor-alpha; Vasodilator Agents

2023
Trimetazidine Improves the Outcome of EECP Therapy in Patients with Refractory Angina Pectoris.
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2020, Volume: 74, Issue:3

    Topics: Angina Pectoris; Chaperonin 60; Chemokine CCL2; Combined Modality Therapy; Counterpulsation; Double-Blind Method; F2-Isoprostanes; Female; Humans; Interleukin-1beta; Male; Middle Aged; Mitochondrial Proteins; Monocytes; Patient Satisfaction; Prospective Studies; Toll-Like Receptor 2; Trimetazidine; Vasodilator Agents

2020
A randomized, double-blind, placebo-controlled trial to assess the efficAcy and safety of Trimetazidine in patients with angina pectoris having been treated by percutaneous coronary intervention (ATPCI study): Rationale, design, and baseline characteristi
    American heart journal, 2019, Volume: 210

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Coronary Artery Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Placebos; Postoperative Complications; Recurrence; Trimetazidine; Vasodilator Agents; Young Adult

2019
Effect of trimetazidine on recurrent angina pectoris and left ventricular structure in elderly multivessel coronary heart disease patients with diabetes mellitus after drug-eluting stent implantation: a single-centre, prospective, randomized, double-blind
    Clinical drug investigation, 2014, Volume: 34, Issue:4

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Coronary Disease; Diabetes Complications; Double-Blind Method; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Secondary Prevention; Treatment Outcome; Trimetazidine; Vasodilator Agents; Ventricular Function, Left

2014
[Evaluation of the myocardial protection of trimetazidine during percutaneous coronary intervention: a multi-center randomized and controlled clinical study].
    Zhonghua nei ke za zhi, 2010, Volume: 49, Issue:6

    Topics: Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Female; Humans; Male; Middle Aged; Trimetazidine; Vasodilator Agents

2010
[The (PRIMA) Study. Comparison of clinical effect of trimetazidine MR in men and women].
    Kardiologiia, 2011, Volume: 51, Issue:6

    Topics: Aged; Angina Pectoris; Cardiotonic Agents; Drug Monitoring; Exercise Test; Female; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Nitro Compounds; Russia; Severity of Illness Index; Sex Factors; Treatment Outcome; Trimetazidine; Vasodilator Agents

2011
[Myocardial cytoprotectors, a reserve therapeutic modality for patients with stable angina of effort].
    Klinicheskaia meditsina, 2011, Volume: 89, Issue:4

    Topics: Aged; Angina Pectoris; Cytoprotection; Drug Therapy, Combination; Female; Humans; Male; Myocardium; Picolines; Trimetazidine; Ubiquinone

2011
[Decrease in the sensitivity to the anti-ischemic effect of propranolol and prospects for correcting it in patients with stable angina pectoris].
    Terapevticheskii arkhiv, 2002, Volume: 74, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Myocardial Ischemia; Placebos; Propranolol; Trimetazidine

2002
[Trimetazidine in pectoris patients older than 65 years with stable angina].
    Kardiologiia, 2002, Volume: 42, Issue:6

    Topics: Aged; Angina Pectoris; Female; Humans; Male; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Trimetazidine; Vasodilator Agents

2002
[Efficacy of trimetazidine in stable angina pectoris refractory to traditional treatment].
    Kardiologiia, 2002, Volume: 42, Issue:3

    Topics: Angina Pectoris; Female; Humans; Male; Middle Aged; Trimetazidine; Vasodilator Agents

2002
Efficacy and tolerability of trimetazidine in stable angina: a meta-analysis of randomized, double-blind, controlled trials.
    Coronary artery disease, 2003, Volume: 14, Issue:2

    Topics: Aged; Angina Pectoris; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Exercise Tolerance; Female; Humans; Male; Middle Aged; Nitroglycerin; Severity of Illness Index; Treatment Outcome; Trimetazidine; Vasodilator Agents

2003
Treatment of stable angina with low dose diltiazem in combination with the metabolic agent trimetazidine.
    International journal of cardiology, 2003, Volume: 88, Issue:1

    Topics: Aged; Angina Pectoris; Apolipoproteins; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Trimetazidine; Vasodilator Agents

2003
[Antiischemic efficacy of trimetazidine in patients with intermittent claudication and effort angina].
    Kardiologiia, 2003, Volume: 43, Issue:7

    Topics: Aged; Angina Pectoris; Arteriosclerosis; Arteriosclerosis Obliterans; Humans; Intermittent Claudication; Male; Middle Aged; Treatment Outcome; Trimetazidine; Vasodilator Agents

2003
[Efficacy and tolerability of trimetazidine in the treatment of stable effort angina (TRIUMPH Study in Russia)].
    Kardiologiia, 2003, Volume: 43, Issue:6

    Topics: Angina Pectoris; Female; Humans; Hypotension; Male; Middle Aged; Nausea; Patient Compliance; Quality of Life; Treatment Outcome; Trimetazidine; Vasodilator Agents

2003
Antianginal effects of trimetazidine and left ventricular function improvement in patients with stable angina pectoris.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2002, Volume: 2, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Chronic Disease; Drug Therapy, Combination; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Nitrates; Treatment Outcome; Trimetazidine; Vasodilator Agents; Ventricular Function, Left

2002
Assessment of anti-ischemic and antianginal effect at trough plasma concentration and safety of trimetazidine MR 35 mg in patients with stable angina pectoris: a multicenter, double-blind, placebo-controlled study.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2003, Volume: 3, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Angina Pectoris; Double-Blind Method; Europe; Exercise Test; Female; Humans; Israel; Latvia; Male; Middle Aged; Myocardial Ischemia; Russia; Severity of Illness Index; Treatment Outcome; Trimetazidine; Vasodilator Agents

2003
Efficacy of trimetazidine in patients with recurrent angina: a subgroup analysis of the TRIMPOL II study.
    Current medical research and opinion, 2004, Volume: 20, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angioplasty, Balloon, Coronary; Coronary Artery Bypass; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Humans; Male; Metoprolol; Middle Aged; Recurrence; Trimetazidine; Vasodilator Agents

2004
Comparison of the effects of trimetazidine and diltiazem on exercise performance in patients with coronary heart disease. The Turkish trimetazidine study (TTS).
    Acta cardiologica, 2004, Volume: 59, Issue:6

    Topics: Adolescent; Adult; Aged; Angina Pectoris; Diltiazem; Double-Blind Method; Exercise Tolerance; Humans; Male; Middle Aged; Prospective Studies; Trimetazidine; Vasodilator Agents

2004
[Anti-ischemic efficacy of combination of trimetazidine with enalapril in patients with stable effort angina and metabolic syndrome].
    Kardiologiia, 2005, Volume: 45, Issue:8

    Topics: Adult; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Electrocardiography, Ambulatory; Enalapril; Female; Follow-Up Studies; Humans; Male; Metabolic Syndrome; Middle Aged; Treatment Outcome; Trimetazidine; Vasodilator Agents

2005
[Trimetazidine in the treatment of stable angina pectoris TRIADA-(trimetazidine in stable angina twice daily)].
    Vnitrni lekarstvi, 2006, Volume: 52, Issue:6

    Topics: Angina Pectoris; Humans; Trimetazidine; Vasodilator Agents

2006
Protective effect of an acute oral loading dose of trimetazidine on myocardial injury following percutaneous coronary intervention.
    Heart (British Cardiac Society), 2007, Volume: 93, Issue:6

    Topics: Administration, Oral; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Female; Heart Injuries; Humans; Male; Middle Aged; Premedication; Prospective Studies; Stents; Trimetazidine; Troponin I; Vasodilator Agents

2007
Trimetazidine to reverse ischemia in patients with class I or II angina: a randomized, double-blind, placebo-controlled dobutamine-atropine stress echocardiography study.
    Coronary artery disease, 2007, Volume: 18, Issue:4

    Topics: Aged; Angina Pectoris; Atropine; Dobutamine; Double-Blind Method; Echocardiography, Stress; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Treatment Outcome; Trimetazidine; Vasodilator Agents

2007
[Program for detection of patients with ineffective therapy with beta-adrenoblockers and comparative assessment of efficacy of addition of trimetazidine MB or isosorbide dinitrate in stable angina. Results of a Russian Study Parrallel].
    Kardiologiia, 2007, Volume: 47, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Angina Pectoris; Data Interpretation, Statistical; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Quality of Life; Risk Factors; Russia; Smoking; Time Factors; Treatment Outcome; Trimetazidine; Vasodilator Agents

2007
Trimetazidine added to combined hemodynamic antianginal therapy in patients with type 2 diabetes: a randomized crossover trial.
    American heart journal, 2007, Volume: 154, Issue:1

    Topics: Angina Pectoris; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Administration Schedule; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Male; Middle Aged; Trimetazidine

2007
[Value of the combination of trimetazidine (Vastarel 20 mg) with diltiazem (Tildiem 60 mg) in stable effort angina. A double-blind versus placebo multicenter study].
    Annales de cardiologie et d'angeiologie, 1995, Volume: 44, Issue:4

    Topics: Angina Pectoris; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Humans; Male; Middle Aged; Physical Exertion; Trimetazidine

1995
Combination therapy of trimetazidine with diltiazem in patients with coronary artery disease. Group of South of France Investigators.
    The American journal of cardiology, 1995, Aug-24, Volume: 76, Issue:6

    Topics: Administration, Oral; Angina Pectoris; Coronary Disease; Diltiazem; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Exercise Test; Humans; Male; Middle Aged; Prospective Studies; Treatment Outcome; Trimetazidine

1995
Trimetazidine European Multicenter Study versus propranolol in stable angina pectoris: contribution of Holter electrocardiographic ambulatory monitoring.
    The American journal of cardiology, 1995, Aug-24, Volume: 76, Issue:6

    Topics: Angina Pectoris; Circadian Rhythm; Double-Blind Method; Electrocardiography, Ambulatory; Europe; Humans; Male; Propranolol; Treatment Outcome; Trimetazidine

1995
Trimetazidine: a new concept in the treatment of angina. Comparison with propranolol in patients with stable angina. Trimetazidine European Multicenter Study Group.
    British journal of clinical pharmacology, 1994, Volume: 37, Issue:3

    Topics: Angina Pectoris; Blood Pressure; Double-Blind Method; Electrocardiography; Exercise Tolerance; Heart Rate; Humans; Male; Middle Aged; Propranolol; Reproducibility of Results; Trimetazidine

1994
Permutation distribution estimation applied to the comparison of the profile of the activity of two antianginal drugs.
    Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:2

    Topics: Angina Pectoris; Data Interpretation, Statistical; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Tolerance; Humans; Male; Middle Aged; Propranolol; Trimetazidine; Vasodilator Agents

1996
Combination treatment with trimetazidine and diltiazem in stable angina pectoris.
    Heart (British Cardiac Society), 1997, Volume: 78, Issue:4

    Topics: Angina Pectoris; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Trimetazidine; Vasodilator Agents

1997
Lack of effects of trimetazidine on systemic hemodynamics in patients with coronary artery disease: a placebo-controlled study.
    Clinical trials and meta-analysis, 1994, Volume: 29, Issue:1

    Topics: Angina Pectoris; Aorta; Blood Pressure; Cardiac Output; Coronary Disease; Double-Blind Method; Exercise Tolerance; Female; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Placebos; Pulmonary Wedge Pressure; Trimetazidine; Vascular Resistance; Ventricular Function, Left; Ventricular Pressure

1994
[Comparative efficacy of combined therapy with preductal and amino acid composition in elderly patients with coronary heart disease and class II-III angina].
    Terapevticheskii arkhiv, 1999, Volume: 71, Issue:11

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Cysteine; Drug Therapy, Combination; Echocardiography; Electrocardiography, Ambulatory; Female; Glutamic Acid; Glycine; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Treatment Outcome; Trimetazidine; Vasodilator Agents

1999
[Effects of metabolic therapy on intracellular level of antioxidant system in elderly patients with ischemic heart disease].
    Klinicheskaia meditsina, 2000, Volume: 78, Issue:1

    Topics: Aged; Amino Acids; Angina Pectoris; Drug Therapy, Combination; Erythrocytes; Female; Glutathione; Humans; Intracellular Fluid; Lipid Peroxidation; Male; Oxidation-Reduction; Oxidoreductases; Treatment Outcome; Trimetazidine; Vasodilator Agents

2000
[Efficacy and tolerance of trimetazidine, a metabolic antianginal, in combination with a hemodynamic antianginal in stable exertion angina. TRIMPOL I, a multicenter study].
    Presse medicale (Paris, France : 1983), 2000, Mar-18, Volume: 29, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium; Drug Evaluation; Drug Therapy, Combination; Exercise Test; Female; Humans; Male; Middle Aged; Nitrates; Trimetazidine; Vasodilator Agents

2000
[Clinical aspects of trimetazidine (preductal) administration as an antianginal drug].
    Terapevticheskii arkhiv, 2000, Volume: 72, Issue:8

    Topics: Administration, Oral; Aged; Aged, 80 and over; Angina Pectoris; Cross-Over Studies; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Prognosis; Propranolol; Trimetazidine; Vasodilator Agents; Verapamil

2000
[Effect of trimetazidine on biological activity of neutrophils in patients with transient myocardial ischemia induced by exercise testing].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2000, Volume: 9, Issue:50

    Topics: Adult; Angina Pectoris; Cell Aggregation; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Neutrophils; Trimetazidine

2000
Trimetazidine as indirect antioxidant.
    Bulletin of experimental biology and medicine, 2000, Volume: 130, Issue:10

    Topics: Angina Pectoris; Antioxidants; Coronary Disease; Erythrocytes; Glutathione Peroxidase; Humans; Lipid Peroxidation; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Superoxide Dismutase; Trimetazidine; Vasodilator Agents

2000
[Combined therapy with nitrosorbide and preductal in patients with ischemic heart disease].
    Voenno-meditsinskii zhurnal, 2000, Volume: 321, Issue:11

    Topics: Angina Pectoris; Drug Therapy, Combination; Humans; Isosorbide Dinitrate; Male; Middle Aged; Trimetazidine

2000
Combination treatment in stable effort angina using trimetazidine and metoprolol: results of a randomized, double-blind, multicentre study (TRIMPOL II). TRIMetazidine in POLand.
    European heart journal, 2001, Volume: 22, Issue:24

    Topics: Administration, Oral; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Europe; Exercise Test; Female; Humans; Male; Metoprolol; Middle Aged; Treatment Outcome; Trimetazidine; Vasodilator Agents

2001
Increase of adenosine plasma levels after oral trimetazidine: a pharmacological preconditioning?
    Pharmacological research, 2002, Volume: 45, Issue:1

    Topics: Adenosine; Aged; Analysis of Variance; Angina Pectoris; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Time Factors; Trimetazidine; Vasodilator Agents

2002
Acute effects of trimetazidine on ergometric parameters in effort angina.
    Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 4

    Topics: Analysis of Variance; Angina Pectoris; Blood Pressure; Double-Blind Method; Electrocardiography; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Trimetazidine

1990
Chronic effects of trimetazidine on ergometric parameters in effort angina.
    Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 4

    Topics: Angina Pectoris; Double-Blind Method; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Time Factors; Trimetazidine

1990
Combination of trimetazidine with nifedipine in effort angina.
    Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 4

    Topics: Angina Pectoris; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Humans; Male; Middle Aged; Nifedipine; Trimetazidine

1990
A new semiautomated algorithm to quantify Holter-detected myocardial ischemia: preliminary experience in the Trimetazidine European Multicenter trial (TEMS).
    Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 4

    Topics: Algorithms; Angina Pectoris; Automation; Circadian Rhythm; Double-Blind Method; Electrocardiography, Ambulatory; Exercise Test; Humans; Trimetazidine

1990
Comparison of trimetazidine with nifedipine in effort angina: a double-blind, crossover study.
    Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 4

    Topics: Adult; Aged; Angina Pectoris; Double-Blind Method; Exercise; Humans; Male; Middle Aged; Nifedipine; Trimetazidine

1990
Trimetazidine and stable angina a double-blind trial.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1990, Volume: 73, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Humans; Male; Medical Records; Middle Aged; Piperazines; Trimetazidine

1990
Therapeutic value of a cardioprotective agent in patients with severe ischaemic cardiomyopathy.
    European heart journal, 1990, Volume: 11, Issue:3

    Topics: Angina Pectoris; Cardiomyopathies; Coronary Disease; Double-Blind Method; Drug Evaluation; Female; Hemodynamics; Humans; Male; Middle Aged; Piperazines; Trimetazidine

1990
[Ergometric effects of a single administration of trimetazidine].
    Presse medicale (Paris, France : 1983), 1986, Oct-16, Volume: 15, Issue:35

    Topics: Administration, Oral; Angina Pectoris; Double-Blind Method; Exercise Test; Humans; Male; Middle Aged; Nitroglycerin; Piperazines; Trimetazidine

1986
[Effectiveness of trimetazidine in stable effort angina due to chronic coronary insufficiency. A double-blind versus placebo study].
    Presse medicale (Paris, France : 1983), 1986, Oct-16, Volume: 15, Issue:35

    Topics: Angina Pectoris; Chronic Disease; Coronary Disease; Double-Blind Method; Exercise Test; Humans; Male; Piperazines; Trimetazidine

1986
[Clinical effectiveness of trimetazidine in stable effort angina. A double-blind versus placebo controlled study].
    Presse medicale (Paris, France : 1983), 1986, Oct-16, Volume: 15, Issue:35

    Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Humans; Male; Middle Aged; Piperazines; Random Allocation; Trimetazidine

1986
[The effects of trimetazidine on ergometric parameters in exercise-induced angina. Controlled multicenter double blind versus placebo study].
    Archives des maladies du coeur et des vaisseaux, 1986, Volume: 79, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Exercise Test; Hemodynamics; Humans; Male; Middle Aged; Physical Exertion; Piperazines; Trimetazidine

1986
Acute effects of trimetazidine evaluated by exercise testing.
    European journal of clinical pharmacology, 1987, Volume: 33, Issue:2

    Topics: Angina Pectoris; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Piperazines; Trimetazidine

1987

Other Studies

32 other study(ies) available for trimetazidine and Angor Pectoris

ArticleYear
Do we need to change the Patient Indications for Trimetazidine after ATPCI?
    The Journal of the Association of Physicians of India, 2021, Volume: 69, Issue:4

    Topics: Angina Pectoris; Humans; Percutaneous Coronary Intervention; Research Design; Trimetazidine; Vasodilator Agents

2021
Clinical Implications of Nicorandil Combined with Trimetazidine in Patients with Coronary Heart Disease: A Real-World Observational Study.
    Advances in therapy, 2022, Volume: 39, Issue:1

    Topics: Adult; Angina Pectoris; Coronary Disease; Humans; Nicorandil; Retrospective Studies; Trimetazidine

2022
Concomitant Use of Ranolazine and Trimetazidine in Patients with Refractory Angina: An Initial Experience.
    Arquivos brasileiros de cardiologia, 2022, Volume: 119, Issue:4

    Topics: Angina Pectoris; Angina, Stable; Cardiovascular Agents; Humans; Ranolazine; Treatment Outcome; Trimetazidine; Vasodilator Agents

2022
Impact of Trimetazidine on the Incident Heart Failure After Coronary Artery Revascularization.
    Journal of cardiovascular pharmacology, 2023, 10-01, Volume: 82, Issue:4

    Topics: Angina Pectoris; Coronary Vessels; Heart Failure; Humans; Treatment Outcome; Trimetazidine; Vasodilator Agents

2023
Trimetazidine for stable and unstable ischemic heart diseases and for heart failure: Is its routine use justified from available data?
    International journal of cardiology, 2020, 02-01, Volume: 300

    Topics: Angina Pectoris; Heart Failure; Humans; Myocardial Ischemia; Trimetazidine

2020
Trimetazidine not beneficial after PCI.
    Nature reviews. Cardiology, 2020, Volume: 17, Issue:11

    Topics: Angina Pectoris; Double-Blind Method; Humans; Percutaneous Coronary Intervention; Trimetazidine; Vasodilator Agents

2020
Trimetazidine: is there a role beyond angina?
    European heart journal. Cardiovascular pharmacotherapy, 2018, 04-01, Volume: 4, Issue:2

    Topics: Angina Pectoris; Humans; Trimetazidine; Vasodilator Agents

2018
Effect of European Medicines Agency's restrictions on trimetazidine utilization in Portugal.
    Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:9

    Topics: Angina Pectoris; Drug Labeling; Drug Prescriptions; Drug Utilization; Drug Utilization Review; European Union; Humans; National Health Programs; Parkinsonian Disorders; Portugal; Retrospective Studies; Trimetazidine; Vasodilator Agents

2018
Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 349, Issue:3

    Topics: Acetyl-CoA C-Acyltransferase; Angina Pectoris; Animals; Cells, Cultured; Diet, High-Fat; Fatty Acids; Glucose Tolerance Test; Insulin; Insulin Resistance; Lipid Metabolism; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Myocytes, Cardiac; Obesity; Oxidation-Reduction; Rats; Trimetazidine; Vasodilator Agents

2014
Long-Term Preservation of Left Ventricular Systolic Function in Patients With Refractory Angina Pectoris and Inducible Myocardial Ischemia on Optimal Medical Therapy.
    The American journal of cardiology, 2016, 05-15, Volume: 117, Issue:10

    Topics: Aged; Angina Pectoris; Benzazepines; Cardiovascular Agents; Echocardiography; Exercise Test; Female; Follow-Up Studies; Humans; Ivabradine; Male; Myocardial Ischemia; Ranolazine; Retrospective Studies; Sodium Channel Blockers; Stroke Volume; Systole; Time Factors; Tomography, Emission-Computed, Single-Photon; Trimetazidine; Vasodilator Agents; Ventricular Function, Left

2016
Real-world Evidence for the Antianginal Efficacy of Trimetazidine from the Russian Observational CHOICE-2 Study.
    Advances in therapy, 2017, Volume: 34, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nitrates; Prospective Studies; Russia; Trimetazidine; Vasodilator Agents

2017
[Treatment of Patients With Stable Ischemic Heart Disease in Real Clinical Practice in Russia. The CHOICE-2 Program].
    Kardiologiia, 2016, Volume: 56, Issue:5

    Topics: Angina Pectoris; Coronary Artery Disease; Humans; Myocardial Ischemia; Russia; Trimetazidine

2016
The effect of trimetazidine added to maximal anti-ischemic therapy in patients with advanced coronary artery disease.
    Cardiology journal, 2008, Volume: 15, Issue:4

    Topics: Aged; Angina Pectoris; Coronary Angiography; Coronary Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Exercise Test; Exercise Tolerance; Female; Follow-Up Studies; Humans; Male; Middle Aged; Probability; Prospective Studies; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Time Factors; Treatment Outcome; Trimetazidine; Vasodilator Agents

2008
[The PRIMA study: trimetazidin in the treatment of patients with stable angina pectoris after myocardial infarction. Epidemiological and clinical phases].
    Kardiologiia, 2008, Volume: 48, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Retrospective Studies; Russia; Survival Rate; Treatment Outcome; Trimetazidine; Vasodilator Agents

2008
Allopurinol for chronic stable angina: old drug, new tricks?
    Lancet (London, England), 2010, Jun-19, Volume: 375, Issue:9732

    Topics: Allopurinol; Angina Pectoris; Cardiovascular Agents; Chronic Disease; Enzyme Inhibitors; Humans; Trimetazidine; Vasodilator Agents

2010
Effect of trimetazidine on exercise performance in patients with coronary artery ectasia.
    Japanese heart journal, 2003, Volume: 44, Issue:4

    Topics: Aged; Angina Pectoris; Coronary Artery Disease; Coronary Circulation; Dilatation, Pathologic; Electrocardiography; Exercise Test; Humans; Male; Middle Aged; Trimetazidine; Vasodilator Agents

2003
Trimetazidine in geriatric patients with stable angina pectoris: the tiger study.
    International journal of clinical practice, 2003, Volume: 57, Issue:10

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Drug Evaluation; Exercise Therapy; Female; Humans; Male; Treatment Outcome; Trimetazidine; Vasodilator Agents

2003
[Assessment of antianginal and antiischemic effect of trimetazidine and its effects on myocardial perfusion in patients with ischemic heart disease and stable angina.].
    Kardiologiia, 2004, Volume: 44, Issue:9

    Topics: Angina Pectoris; Angina, Stable; Coronary Artery Disease; Humans; Myocardial Ischemia; Trimetazidine; Vasodilator Agents

2004
Treatment of stable angina pectoris with trimetazidine modified release in Indian primary-care practice.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2005, Volume: 5, Issue:5

    Topics: Aged; Angina Pectoris; Delayed-Action Preparations; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lipids; Male; Middle Aged; Primary Health Care; Prospective Studies; Trimetazidine; Vasodilator Agents

2005
Modified-release formulation of trimetazidine for exceptional control of angina pectoris: fact or fiction.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2005, Volume: 5, Issue:5

    Topics: Angina Pectoris; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Administration Schedule; Drug Therapy, Combination; Humans; Trimetazidine; Vasodilator Agents

2005
[Treatment of stable angina pectoris with trimetazidine].
    Vnitrni lekarstvi, 2006, Volume: 52, Issue:6

    Topics: Angina Pectoris; Humans; Trimetazidine; Vasodilator Agents

2006
[Modulation of myocardial metabolism with trimetazidine].
    Vnitrni lekarstvi, 2006, Volume: 52, Issue:6

    Topics: Angina Pectoris; Energy Metabolism; Humans; Myocardium; Trimetazidine; Vasodilator Agents

2006
[Derangements of contractility of left ventricular myocardium in patients subjected to coronary bypass surgery. Methods of their correction].
    Kardiologiia, 2007, Volume: 47, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Cardiotonic Agents; Coronary Artery Bypass; Female; Humans; Male; Methylhydrazines; Middle Aged; Myocardial Contraction; Postoperative Complications; Trimetazidine; Ventricular Dysfunction, Left

2007
[Therapeutic application of myocardial cytoprotection].
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1994, Volume: 13, Issue:9

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Carnitine; Humans; Myocardial Ischemia; Niacinamide; Nicorandil; Piperazines; Ranolazine; Trimetazidine; Vasodilator Agents

1994
[The use of trimetazidine in the combined therapy of postinfarct stenocardia].
    Terapevticheskii arkhiv, 1997, Volume: 69, Issue:1

    Topics: Acute Disease; Aged; Angina Pectoris; Drug Evaluation; Humans; Male; Myocardial Infarction; Trimetazidine; Vasodilator Agents

1997
Angina, myocardial hibernation and trimetazidine.
    International journal of clinical practice, 1997, Volume: 51, Issue:6

    Topics: Angina Pectoris; Humans; Myocardial Ischemia; Myocardial Stunning; Trimetazidine; Vasodilator Agents

1997
The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase.
    Circulation research, 2000, Mar-17, Volume: 86, Issue:5

    Topics: Angina Pectoris; Animals; Carboxy-Lyases; Dose-Response Relationship, Drug; Energy Metabolism; Esters; Fatty Acids; Glucose; Glycolysis; Male; Malonyl Coenzyme A; Mitochondria; Mitochondrial Trifunctional Protein; Multienzyme Complexes; Myocardial Ischemia; Myocardium; Pyruvate Dehydrogenase Complex; Rats; Rats, Sprague-Dawley; Trimetazidine; Vasodilator Agents

2000
Haemodynamic and metabolic agents in the treatment of stable angina: publication review.
    Coronary artery disease, 2001, Volume: 12 Suppl 1

    Topics: Angina Pectoris; Energy Metabolism; Hemodynamics; Humans; Myocardium; Trimetazidine; Vasodilator Agents

2001
Comments on EMIP-FR study's editorial.
    European heart journal, 2001, Volume: 22, Issue:15

    Topics: Angina Pectoris; Humans; Myocardial Infarction; Treatment Outcome; Trimetazidine; Vasodilator Agents

2001
Trimetazidine: a second look. Just a placebo.
    Prescrire international, 2000, Volume: 9, Issue:45

    Topics: Angina Pectoris; Drug Therapy, Combination; France; Humans; Placebos; Propranolol; Randomized Controlled Trials as Topic; Tinnitus; Treatment Outcome; Trimetazidine; Vasodilator Agents; Vertigo

2000
Is the antianginal action of trimetazidine independent of hemodynamic changes?
    Cardiovascular drugs and therapy, 1991, Volume: 5, Issue:6

    Topics: Angina Pectoris; Animals; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Trimetazidine

1991
[Current concepts in cellular ischemia: role of trimetazidine].
    Annales de cardiologie et d'angeiologie, 1986, Oct-15, Volume: 35, Issue:7 Pt 2

    Topics: Angina Pectoris; Double-Blind Method; Drug Evaluation; Electrocardiography; Hemodynamics; Humans; Physical Exertion; Piperazines; Random Allocation; Trimetazidine

1986