trimebutine has been researched along with Pain in 3 studies
Trimebutine: Proposed spasmolytic with possible local anesthetic action used in gastrointestinal disorders.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Excerpt | Relevance | Reference |
---|---|---|
"Trimebutine is a weak opioid receptor agonist used in the treatment of IBS." | 5.35 | A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. ( Caliendo, G; Distrutti, E; Fiorucci, S; Mencarelli, A; Renga, B; Santagada, V; Severino, B, 2009) |
"Trimebutine (2-dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoate, hydrogen maleate) relieves abdominal pain in humans." | 3.70 | Antinociceptive effect of (S)-N-desmethyl trimebutine against a mechanical stimulus in a rat model of peripheral neuropathy. ( Christensen, D; Guilbaud, G; Kayser, V; Roman, F, 2000) |
"Trimebutine is a weak opioid receptor agonist used in the treatment of IBS." | 1.35 | A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. ( Caliendo, G; Distrutti, E; Fiorucci, S; Mencarelli, A; Renga, B; Santagada, V; Severino, B, 2009) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (66.67) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (33.33) | 2.80 |
Authors | Studies |
---|---|
Makarova, AA | 2 |
Diukova, GM | 2 |
Ruchkina, IN | 2 |
Romashkina, NV | 2 |
Indejkina, LK | 2 |
Degterev, DA | 2 |
Dbar, SR | 2 |
Parfenov, AI | 2 |
Distrutti, E | 1 |
Mencarelli, A | 1 |
Renga, B | 1 |
Caliendo, G | 1 |
Santagada, V | 1 |
Severino, B | 1 |
Fiorucci, S | 1 |
Kayser, V | 1 |
Christensen, D | 1 |
Guilbaud, G | 1 |
Roman, F | 1 |
1 trial available for trimebutine and Pain
Article | Year |
---|---|
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser | 2022 |
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser | 2022 |
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser | 2022 |
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser | 2022 |
2 other studies available for trimebutine and Pain
Article | Year |
---|---|
A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats.
Topics: Animals; Colitis; Colon; Dilatation, Pathologic; Gastrointestinal Agents; Gene Expression Profiling; | 2009 |
Antinociceptive effect of (S)-N-desmethyl trimebutine against a mechanical stimulus in a rat model of peripheral neuropathy.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Hindlimb; Male; Naloxone; Narcotic Antagonist | 2000 |