trimebutine and Pain
trimebutine has been researched along with Pain in 3 studies
Trimebutine: Proposed spasmolytic with possible local anesthetic action used in gastrointestinal disorders.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trimebutine is a weak opioid receptor agonist used in the treatment of IBS." | 5.35 | A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. ( Caliendo, G; Distrutti, E; Fiorucci, S; Mencarelli, A; Renga, B; Santagada, V; Severino, B, 2009) |
| "Trimebutine (2-dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoate, hydrogen maleate) relieves abdominal pain in humans." | 3.70 | Antinociceptive effect of (S)-N-desmethyl trimebutine against a mechanical stimulus in a rat model of peripheral neuropathy. ( Christensen, D; Guilbaud, G; Kayser, V; Roman, F, 2000) |
| "Trimebutine is a weak opioid receptor agonist used in the treatment of IBS." | 1.35 | A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. ( Caliendo, G; Distrutti, E; Fiorucci, S; Mencarelli, A; Renga, B; Santagada, V; Severino, B, 2009) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Makarova, AA | 2 |
| Diukova, GM | 2 |
| Ruchkina, IN | 2 |
| Romashkina, NV | 2 |
| Indejkina, LK | 2 |
| Degterev, DA | 2 |
| Dbar, SR | 2 |
| Parfenov, AI | 2 |
| Distrutti, E | 1 |
| Mencarelli, A | 1 |
| Renga, B | 1 |
| Caliendo, G | 1 |
| Santagada, V | 1 |
| Severino, B | 1 |
| Fiorucci, S | 1 |
| Kayser, V | 1 |
| Christensen, D | 1 |
| Guilbaud, G | 1 |
| Roman, F | 1 |
Trials
1 trial available for trimebutine and Pain
| Article | Year |
|---|---|
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser | 2022 |
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser | 2022 |
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser | 2022 |
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser | 2022 |
Other Studies
2 other studies available for trimebutine and Pain
| Article | Year |
|---|---|
A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats.
Topics: Animals; Colitis; Colon; Dilatation, Pathologic; Gastrointestinal Agents; Gene Expression Profiling; | 2009 |
Antinociceptive effect of (S)-N-desmethyl trimebutine against a mechanical stimulus in a rat model of peripheral neuropathy.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Hindlimb; Male; Naloxone; Narcotic Antagonist | 2000 |