trimebutine has been researched along with Inflammation in 2 studies
Trimebutine: Proposed spasmolytic with possible local anesthetic action used in gastrointestinal disorders.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trimebutine is a weak opioid receptor agonist used in the treatment of IBS." | 5.35 | A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. ( Caliendo, G; Distrutti, E; Fiorucci, S; Mencarelli, A; Renga, B; Santagada, V; Severino, B, 2009) |
| "We previously identified papaverine as an inhibitor of receptor for advanced glycation end-products (RAGE) and showed its suppressive effect on high mobility group box 1 (HMGB1)-mediated responses to inflammation." | 3.96 | Trimebutine attenuates high mobility group box 1-receptor for advanced glycation end-products inflammatory signaling pathways. ( Abe, H; Abe, T; Inoue, S; Kamiya, T; Nakajima, S; Ogawa, N; Okazawa, M; Oyama, T; Sato, A; Tachibana, H; Tamada, K; Tanuma, SI; Uchiumi, F; Yokomizo, T; Yokoue, N; Yoshimori, A; Yoshizawa, K, 2020) |
| "Trimebutine is a weak opioid receptor agonist used in the treatment of IBS." | 1.35 | A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats. ( Caliendo, G; Distrutti, E; Fiorucci, S; Mencarelli, A; Renga, B; Santagada, V; Severino, B, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakajima, S | 1 |
| Ogawa, N | 1 |
| Yokoue, N | 1 |
| Tachibana, H | 1 |
| Tamada, K | 1 |
| Okazawa, M | 1 |
| Sato, A | 1 |
| Oyama, T | 1 |
| Abe, H | 1 |
| Kamiya, T | 1 |
| Yoshimori, A | 1 |
| Yoshizawa, K | 1 |
| Inoue, S | 1 |
| Yokomizo, T | 1 |
| Uchiumi, F | 1 |
| Abe, T | 1 |
| Tanuma, SI | 1 |
| Distrutti, E | 1 |
| Mencarelli, A | 1 |
| Renga, B | 1 |
| Caliendo, G | 1 |
| Santagada, V | 1 |
| Severino, B | 1 |
| Fiorucci, S | 1 |
2 other studies available for trimebutine and Inflammation
| Article | Year |
|---|---|
Trimebutine attenuates high mobility group box 1-receptor for advanced glycation end-products inflammatory signaling pathways.
Topics: Animals; HMGB1 Protein; Inflammation; Interleukin-6; Janus Kinases; Macrophages; MAP Kinase Signalin | 2020 |
A nitro-arginine derivative of trimebutine (NO2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats.
Topics: Animals; Colitis; Colon; Dilatation, Pathologic; Gastrointestinal Agents; Gene Expression Profiling; | 2009 |