trimebutine has been researched along with Dyspepsia in 11 studies
Trimebutine: Proposed spasmolytic with possible local anesthetic action used in gastrointestinal disorders.
Dyspepsia: Impaired digestion, especially after eating.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe the efficacy and adverse drug reaction of trimebutine maleate in treating patients with functional dyspepsia (FD) coexisting with diarrhea dominant irritable bowel syndrome (IBS-D)." | 9.12 | [A randomized and case-control clinical study on trimebutine maleate in treating functional dyspepsia coexisting with diarrhea-dominant irritable bowel syndrome]. ( Guo, JN; Li, HJ; Lin, YH; Yan, R; Zeng, ZY; Zhong, YQ; Zhu, J, 2007) |
| "The study was designed to investigate the effect of trimebutine maleate, a drug used in both hyperkinetic and hypokinetic motility disorders, on gastric emptying in patients with non-ulcer dyspepsia having prolonged gastric emptying rates and to compare the parameters used for the determination of the lag period observed during the emptying of solid foods from the stomach." | 9.09 | The effect of trimebutine maleate on gastric emptying in patients with non-ulcer dyspepsia. ( Aktas, A; Bayhan, H; Caner, B; Mentes, T; Narin, Y; Ozturk, F, 1999) |
| "To develop a novel combination tablet which contained 100 mg trimebutine maleate and 5 mg mosapride citrate (TMCT) for the treatment of functional dyspepsia, the wet granulation method was used to prepare TMCTs with various amounts of diluents and stabilizers." | 7.76 | Development of a novel combination tablet containing trimebutine maleate and mosapride citrate for the treatment of functional dyspepsia. ( Cho, KH; Choi, HG; Choi, YK; Kang, JH; Park, YJ; Yong, CS, 2010) |
| "To observe the efficacy and adverse drug reaction of trimebutine maleate in treating patients with functional dyspepsia (FD) coexisting with diarrhea dominant irritable bowel syndrome (IBS-D)." | 5.12 | [A randomized and case-control clinical study on trimebutine maleate in treating functional dyspepsia coexisting with diarrhea-dominant irritable bowel syndrome]. ( Guo, JN; Li, HJ; Lin, YH; Yan, R; Zeng, ZY; Zhong, YQ; Zhu, J, 2007) |
| "The study was designed to investigate the effect of trimebutine maleate, a drug used in both hyperkinetic and hypokinetic motility disorders, on gastric emptying in patients with non-ulcer dyspepsia having prolonged gastric emptying rates and to compare the parameters used for the determination of the lag period observed during the emptying of solid foods from the stomach." | 5.09 | The effect of trimebutine maleate on gastric emptying in patients with non-ulcer dyspepsia. ( Aktas, A; Bayhan, H; Caner, B; Mentes, T; Narin, Y; Ozturk, F, 1999) |
| "To develop a novel combination tablet which contained 100 mg trimebutine maleate and 5 mg mosapride citrate (TMCT) for the treatment of functional dyspepsia, the wet granulation method was used to prepare TMCTs with various amounts of diluents and stabilizers." | 3.76 | Development of a novel combination tablet containing trimebutine maleate and mosapride citrate for the treatment of functional dyspepsia. ( Cho, KH; Choi, HG; Choi, YK; Kang, JH; Park, YJ; Yong, CS, 2010) |
| "Trimebutine was prescribed in accordance with the instructions for medical use: orally, 300 mg twice per day for 28 days." | 1.62 | [Efficacy of trimebutine in the treatment of functional gastrointestinal disorders: an observational multicenter study]. ( Andreev, DN; Maev, IV, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Andreev, DN | 1 |
| Maev, IV | 1 |
| Kountouras, J | 1 |
| Gavalas, E | 1 |
| Papaefthymiou, A | 1 |
| Tsechelidis, I | 1 |
| Polyzos, SA | 1 |
| Bor, S | 1 |
| Diculescu, M | 1 |
| Jadallah, Κ | 1 |
| Tadeusz, M | 1 |
| Karakan, T | 1 |
| Bochenek, Α | 1 |
| Rozciecha, J | 1 |
| Dabrowski, P | 1 |
| Sparchez, Z | 1 |
| Sezgin, O | 1 |
| Gülten, M | 1 |
| Farsakh, NA | 1 |
| Doulberis, M | 1 |
| Yang, YJ | 1 |
| Bang, CS | 1 |
| Baik, GH | 1 |
| Park, TY | 1 |
| Shin, SP | 1 |
| Suk, KT | 1 |
| Kim, DJ | 1 |
| Cho, KH | 1 |
| Choi, YK | 1 |
| Kang, JH | 1 |
| Choi, HG | 1 |
| Yong, CS | 1 |
| Park, YJ | 1 |
| Hiyama, T | 2 |
| Yoshihara, M | 2 |
| Matsuo, K | 2 |
| Kusunoki, H | 2 |
| Kamada, T | 2 |
| Ito, M | 2 |
| Tanaka, S | 2 |
| Nishi, N | 1 |
| Chayama, K | 2 |
| Haruma, K | 2 |
| Zhong, YQ | 1 |
| Zhu, J | 1 |
| Guo, JN | 1 |
| Yan, R | 1 |
| Li, HJ | 1 |
| Lin, YH | 1 |
| Zeng, ZY | 1 |
| Walters, JM | 1 |
| Crean, P | 1 |
| McCarthy, CF | 1 |
| Aktas, A | 1 |
| Caner, B | 1 |
| Ozturk, F | 1 |
| Bayhan, H | 1 |
| Narin, Y | 1 |
| Mentes, T | 1 |
| Hongo, M | 1 |
| Satake, M | 1 |
| Fraitag, B | 1 |
| Hostein, J | 1 |
| Pascaud, X | 1 |
| Junien, JL | 1 |
5 reviews available for trimebutine and Dyspepsia
| Article | Year |
|---|---|
Prokinetics for the treatment of functional dyspepsia: Bayesian network meta-analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Bayes Theorem; Benzamides; Benzyl Compounds | 2017 |
Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia.
Topics: Benzamides; Benzyl Compounds; Cisapride; Domperidone; Dopamine Antagonists; Dyspepsia; Gastrointesti | 2007 |
Treatment of functional dyspepsia with serotonin agonists: a meta-analysis of randomized controlled trials.
Topics: Benzamides; Cisapride; Data Interpretation, Statistical; Dopamine Antagonists; Dyspepsia; Gastrointe | 2007 |
[Prokinetics of gastrointestinal system; its newer aspects with regard to motillity stimulants].
Topics: Acetylcholine; Benzamides; Cisapride; Domperidone; Dyspepsia; Gastrointestinal Agents; Gastrointesti | 2002 |
[Trimebutine. Pharmacology, recent concepts about its mechanism of action, therapeutic results].
Topics: Clinical Trials as Topic; Colon; Colonic Diseases, Functional; Constipation; Dyspepsia; Endorphins; | 1992 |
5 trials available for trimebutine and Dyspepsia
| Article | Year |
|---|---|
Trimebutine Maleate Monotherapy for Functional Dyspepsia: A Multicenter, Randomized, Double-Blind Placebo Controlled Prospective Trial.
Topics: Adult; Double-Blind Method; Dyspepsia; Female; Gastrointestinal Agents; Greece; Humans; Jordan; Male | 2020 |
[A randomized and case-control clinical study on trimebutine maleate in treating functional dyspepsia coexisting with diarrhea-dominant irritable bowel syndrome].
Topics: Adolescent; Adult; Case-Control Studies; Constipation; Diarrhea; Dyspepsia; Female; Gastrointestinal | 2007 |
Trimebutine, a new antispasmodic in the treatment of dyspepsia.
Topics: Adolescent; Adult; Aged; Benzoates; Dyspepsia; Female; Humans; Male; Middle Aged; Parasympatholytics | 1980 |
The effect of trimebutine maleate on gastric emptying in patients with non-ulcer dyspepsia.
Topics: Administration, Oral; Adult; Colloids; Dyspepsia; Eating; Female; Gamma Cameras; Gastric Emptying; G | 1999 |
[Trimebutine. Pharmacology, recent concepts about its mechanism of action, therapeutic results].
Topics: Clinical Trials as Topic; Colon; Colonic Diseases, Functional; Constipation; Dyspepsia; Endorphins; | 1992 |
2 other studies available for trimebutine and Dyspepsia
| Article | Year |
|---|---|
[Efficacy of trimebutine in the treatment of functional gastrointestinal disorders: an observational multicenter study].
Topics: Abdominal Pain; Dyspepsia; Female; Gastrointestinal Diseases; Humans; Irritable Bowel Syndrome; Male | 2021 |
Development of a novel combination tablet containing trimebutine maleate and mosapride citrate for the treatment of functional dyspepsia.
Topics: Animals; Benzamides; Biological Availability; Dogs; Drug Combinations; Drug Compounding; Drug Stabil | 2010 |