Page last updated: 2024-11-05

trimebutine and Dyspepsia

trimebutine has been researched along with Dyspepsia in 11 studies

Trimebutine: Proposed spasmolytic with possible local anesthetic action used in gastrointestinal disorders.

Dyspepsia: Impaired digestion, especially after eating.

Research Excerpts

ExcerptRelevanceReference
"To observe the efficacy and adverse drug reaction of trimebutine maleate in treating patients with functional dyspepsia (FD) coexisting with diarrhea dominant irritable bowel syndrome (IBS-D)."9.12[A randomized and case-control clinical study on trimebutine maleate in treating functional dyspepsia coexisting with diarrhea-dominant irritable bowel syndrome]. ( Guo, JN; Li, HJ; Lin, YH; Yan, R; Zeng, ZY; Zhong, YQ; Zhu, J, 2007)
"The study was designed to investigate the effect of trimebutine maleate, a drug used in both hyperkinetic and hypokinetic motility disorders, on gastric emptying in patients with non-ulcer dyspepsia having prolonged gastric emptying rates and to compare the parameters used for the determination of the lag period observed during the emptying of solid foods from the stomach."9.09The effect of trimebutine maleate on gastric emptying in patients with non-ulcer dyspepsia. ( Aktas, A; Bayhan, H; Caner, B; Mentes, T; Narin, Y; Ozturk, F, 1999)
"To develop a novel combination tablet which contained 100 mg trimebutine maleate and 5 mg mosapride citrate (TMCT) for the treatment of functional dyspepsia, the wet granulation method was used to prepare TMCTs with various amounts of diluents and stabilizers."7.76Development of a novel combination tablet containing trimebutine maleate and mosapride citrate for the treatment of functional dyspepsia. ( Cho, KH; Choi, HG; Choi, YK; Kang, JH; Park, YJ; Yong, CS, 2010)
"To observe the efficacy and adverse drug reaction of trimebutine maleate in treating patients with functional dyspepsia (FD) coexisting with diarrhea dominant irritable bowel syndrome (IBS-D)."5.12[A randomized and case-control clinical study on trimebutine maleate in treating functional dyspepsia coexisting with diarrhea-dominant irritable bowel syndrome]. ( Guo, JN; Li, HJ; Lin, YH; Yan, R; Zeng, ZY; Zhong, YQ; Zhu, J, 2007)
"The study was designed to investigate the effect of trimebutine maleate, a drug used in both hyperkinetic and hypokinetic motility disorders, on gastric emptying in patients with non-ulcer dyspepsia having prolonged gastric emptying rates and to compare the parameters used for the determination of the lag period observed during the emptying of solid foods from the stomach."5.09The effect of trimebutine maleate on gastric emptying in patients with non-ulcer dyspepsia. ( Aktas, A; Bayhan, H; Caner, B; Mentes, T; Narin, Y; Ozturk, F, 1999)
"To develop a novel combination tablet which contained 100 mg trimebutine maleate and 5 mg mosapride citrate (TMCT) for the treatment of functional dyspepsia, the wet granulation method was used to prepare TMCTs with various amounts of diluents and stabilizers."3.76Development of a novel combination tablet containing trimebutine maleate and mosapride citrate for the treatment of functional dyspepsia. ( Cho, KH; Choi, HG; Choi, YK; Kang, JH; Park, YJ; Yong, CS, 2010)
"Trimebutine was prescribed in accordance with the instructions for medical use: orally, 300 mg twice per day for 28 days."1.62[Efficacy of trimebutine in the treatment of functional gastrointestinal disorders: an observational multicenter study]. ( Andreev, DN; Maev, IV, 2021)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's2 (18.18)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Andreev, DN1
Maev, IV1
Kountouras, J1
Gavalas, E1
Papaefthymiou, A1
Tsechelidis, I1
Polyzos, SA1
Bor, S1
Diculescu, M1
Jadallah, Κ1
Tadeusz, M1
Karakan, T1
Bochenek, Α1
Rozciecha, J1
Dabrowski, P1
Sparchez, Z1
Sezgin, O1
Gülten, M1
Farsakh, NA1
Doulberis, M1
Yang, YJ1
Bang, CS1
Baik, GH1
Park, TY1
Shin, SP1
Suk, KT1
Kim, DJ1
Cho, KH1
Choi, YK1
Kang, JH1
Choi, HG1
Yong, CS1
Park, YJ1
Hiyama, T2
Yoshihara, M2
Matsuo, K2
Kusunoki, H2
Kamada, T2
Ito, M2
Tanaka, S2
Nishi, N1
Chayama, K2
Haruma, K2
Zhong, YQ1
Zhu, J1
Guo, JN1
Yan, R1
Li, HJ1
Lin, YH1
Zeng, ZY1
Walters, JM1
Crean, P1
McCarthy, CF1
Aktas, A1
Caner, B1
Ozturk, F1
Bayhan, H1
Narin, Y1
Mentes, T1
Hongo, M1
Satake, M1
Fraitag, B1
Hostein, J1
Pascaud, X1
Junien, JL1

Reviews

5 reviews available for trimebutine and Dyspepsia

ArticleYear
Prokinetics for the treatment of functional dyspepsia: Bayesian network meta-analysis.
    BMC gastroenterology, 2017, Jun-26, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Bayes Theorem; Benzamides; Benzyl Compounds

2017
Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:3

    Topics: Benzamides; Benzyl Compounds; Cisapride; Domperidone; Dopamine Antagonists; Dyspepsia; Gastrointesti

2007
Treatment of functional dyspepsia with serotonin agonists: a meta-analysis of randomized controlled trials.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:10

    Topics: Benzamides; Cisapride; Data Interpretation, Statistical; Dopamine Antagonists; Dyspepsia; Gastrointe

2007
[Prokinetics of gastrointestinal system; its newer aspects with regard to motillity stimulants].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2

    Topics: Acetylcholine; Benzamides; Cisapride; Domperidone; Dyspepsia; Gastrointestinal Agents; Gastrointesti

2002
[Trimebutine. Pharmacology, recent concepts about its mechanism of action, therapeutic results].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:5

    Topics: Clinical Trials as Topic; Colon; Colonic Diseases, Functional; Constipation; Dyspepsia; Endorphins;

1992

Trials

5 trials available for trimebutine and Dyspepsia

ArticleYear
Trimebutine Maleate Monotherapy for Functional Dyspepsia: A Multicenter, Randomized, Double-Blind Placebo Controlled Prospective Trial.
    Medicina (Kaunas, Lithuania), 2020, Jul-08, Volume: 56, Issue:7

    Topics: Adult; Double-Blind Method; Dyspepsia; Female; Gastrointestinal Agents; Greece; Humans; Jordan; Male

2020
[A randomized and case-control clinical study on trimebutine maleate in treating functional dyspepsia coexisting with diarrhea-dominant irritable bowel syndrome].
    Zhonghua nei ke za zhi, 2007, Volume: 46, Issue:11

    Topics: Adolescent; Adult; Case-Control Studies; Constipation; Diarrhea; Dyspepsia; Female; Gastrointestinal

2007
Trimebutine, a new antispasmodic in the treatment of dyspepsia.
    Irish medical journal, 1980, Volume: 73, Issue:10

    Topics: Adolescent; Adult; Aged; Benzoates; Dyspepsia; Female; Humans; Male; Middle Aged; Parasympatholytics

1980
The effect of trimebutine maleate on gastric emptying in patients with non-ulcer dyspepsia.
    Annals of nuclear medicine, 1999, Volume: 13, Issue:4

    Topics: Administration, Oral; Adult; Colloids; Dyspepsia; Eating; Female; Gamma Cameras; Gastric Emptying; G

1999
[Trimebutine. Pharmacology, recent concepts about its mechanism of action, therapeutic results].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:5

    Topics: Clinical Trials as Topic; Colon; Colonic Diseases, Functional; Constipation; Dyspepsia; Endorphins;

1992

Other Studies

2 other studies available for trimebutine and Dyspepsia

ArticleYear
[Efficacy of trimebutine in the treatment of functional gastrointestinal disorders: an observational multicenter study].
    Terapevticheskii arkhiv, 2021, Aug-15, Volume: 93, Issue:8

    Topics: Abdominal Pain; Dyspepsia; Female; Gastrointestinal Diseases; Humans; Irritable Bowel Syndrome; Male

2021
Development of a novel combination tablet containing trimebutine maleate and mosapride citrate for the treatment of functional dyspepsia.
    International journal of pharmaceutics, 2010, Nov-15, Volume: 400, Issue:1-2

    Topics: Animals; Benzamides; Biological Availability; Dogs; Drug Combinations; Drug Compounding; Drug Stabil

2010