Page last updated: 2024-11-05

trimebutine and Colonic Diseases, Functional

trimebutine has been researched along with Colonic Diseases, Functional in 13 studies

Trimebutine: Proposed spasmolytic with possible local anesthetic action used in gastrointestinal disorders.

Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.

Research Excerpts

ExcerptRelevanceReference
"001) more effective than placebo, but not significantly so when the dosage level was halved."2.65A three-part controlled study of trimebutine in the treatment of irritable colon syndrome. ( Lüttecke, K, 1980)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19909 (69.23)18.7374
1990's4 (30.77)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Copé, R1
Lüttecke, K2
Fielding, JF1
Chevrel, B1
Parfenov, AI1
Moshal, MG1
Herron, M1
Shimada, A1
Takano, M1
Fraitag, B1
Hostein, J1
Pascaud, X1
Junien, JL1
Matsue, T1
Yamato, S1
Umeda, N1
Galeone, M2
Benazzi, E2
Bossi, M1
Moise, G2
Riva, A2
Stock, F2
Cacioli, D1
Frexinos, J1
Fioramonti, J1
Bueno, L1

Reviews

2 reviews available for trimebutine and Colonic Diseases, Functional

ArticleYear
[Irritable bowel syndrome in adolescence].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50, Issue:11

    Topics: Adolescent; Adult; Age Factors; Anti-Anxiety Agents; Colonic Diseases, Functional; Female; Humans; M

1992
[Trimebutine. Pharmacology, recent concepts about its mechanism of action, therapeutic results].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:5

    Topics: Clinical Trials as Topic; Colon; Colonic Diseases, Functional; Constipation; Dyspepsia; Endorphins;

1992

Trials

10 trials available for trimebutine and Colonic Diseases, Functional

ArticleYear
[Comparative clinical study of the combination of clidinium(br)-chlordiazepoxide and trimebutine in the treatment of functional colopathies].
    Medecine & chirurgie digestives, 1981, Volume: 10, Issue:8

    Topics: Adult; Benzoates; Chlordiazepoxide; Colonic Diseases, Functional; Double-Blind Method; Drug Combinat

1981
A three-part controlled study of trimebutine in the treatment of irritable colon syndrome.
    Current medical research and opinion, 1980, Volume: 6, Issue:6

    Topics: Adult; Aged; Benzoates; Clinical Trials as Topic; Colonic Diseases, Functional; Double-Blind Method;

1980
Double blind trial of trimebutine in the irritable bowel syndrome.
    Irish medical journal, 1980, Volume: 73, Issue:10

    Topics: Adolescent; Adult; Benzoates; Clinical Trials as Topic; Colonic Diseases, Functional; Double-Blind M

1980
[A new treatment of functional colopathies: Modulite].
    Medecine & chirurgie digestives, 1982, Volume: 11, Issue:2

    Topics: Benzoates; Colonic Diseases, Functional; Double-Blind Method; Drug Combinations; Humans; Sorbitol; T

1982
A trial of trimebutine in spastic colon.
    The Journal of international medical research, 1978, Volume: 6, Issue:2

    Topics: Adult; Aged; Benzoates; Clinical Trials as Topic; Colonic Diseases, Functional; Double-Blind Method;

1978
A clinical trial of trimebutine (Mebutin) in spastic colon.
    The Journal of international medical research, 1979, Volume: 7, Issue:3

    Topics: Adult; Benzoates; Colonic Diseases, Functional; Double-Blind Method; Female; Gastrointestinal Motili

1979
[Trimebutine. Pharmacology, recent concepts about its mechanism of action, therapeutic results].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:5

    Topics: Clinical Trials as Topic; Colon; Colonic Diseases, Functional; Constipation; Dyspepsia; Endorphins;

1992
[Clinical and instrumental evaluation by multiple colonic manometry of tiropramide, trimebutine and octylonium bromide in irritable colon. II. Repeated oral administration].
    Pharmatherapeutica, 1986, Volume: 4, Issue:8

    Topics: Administration, Oral; Adult; Benzoates; Colonic Diseases, Functional; Female; Gastrointestinal Motil

1986
[Clinical and instrumental evaluation by multiple colonic manometry of tiropramide, trimebutine and octylonium bromide in the irritable colon: I. Administration by single i.v].
    Pharmatherapeutica, 1986, Volume: 4, Issue:7

    Topics: Adult; Benzoates; Colonic Diseases, Functional; Drug Evaluation; Female; Humans; Injections, Intrave

1986
Effect of trimebutine on colonic myoelectrical activity in IBS patients.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:2

    Topics: Adult; Aged; Benzoates; Colon; Colonic Diseases, Functional; Electromyography; Female; Gastrointesti

1985

Other Studies

2 other studies available for trimebutine and Colonic Diseases, Functional

ArticleYear
[The use of Debridat in treating the irritable bowel syndrome].
    Voenno-meditsinskii zhurnal, 1996, Volume: 317, Issue:5

    Topics: Adolescent; Adult; Aged; Colonic Diseases, Functional; Drug Evaluation; Female; Gastrointestinal Age

1996
[Mechanism of action of trimebutine maleate on gastro-colic reflex in patients with irritable bowel syndrome].
    Nihon Heikatsukin Gakkai zasshi, 1990, Volume: 26, Issue:2

    Topics: Abdominal Pain; Adult; Animals; Chronic Disease; Colon; Colonic Diseases, Functional; Female; Humans

1990