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trimebutine and Colitis, Mucous

trimebutine has been researched along with Colitis, Mucous in 12 studies

Trimebutine: Proposed spasmolytic with possible local anesthetic action used in gastrointestinal disorders.

Research Excerpts

ExcerptRelevanceReference
"To observe the efficacy and adverse drug reaction of trimebutine maleate in treating patients with functional dyspepsia (FD) coexisting with diarrhea dominant irritable bowel syndrome (IBS-D)."9.12[A randomized and case-control clinical study on trimebutine maleate in treating functional dyspepsia coexisting with diarrhea-dominant irritable bowel syndrome]. ( Guo, JN; Li, HJ; Lin, YH; Yan, R; Zeng, ZY; Zhong, YQ; Zhu, J, 2007)
"Trimebutine improved symptoms and psychological adjustment to illness in irritable bowel syndrome in comparison with placebo."9.12The effect of trimebutine on the psychosocial adjustment to illness in the irritable bowel syndrome. ( Dumitraşcu, DL; Stănculete, M, 2006)
"Trimebutine maleate, which modulates the calcium and potassium channels, relieves abdominal pain in patients with irritable bowel syndrome."7.76Effectiveness of trimebutine maleate on modulating intestinal hypercontractility in a mouse model of postinfectious irritable bowel syndrome. ( Hou, X; Liu, Y; Long, Y; Qian, W; Tong, J, 2010)
"Fenoverine acts as a synchronizer of smooth muscle in modulating the intracellular influx of calcium."6.78[Efficacy of fenoverine and trimebutine in the management of irritable bowel syndrome: multicenter randomized double-blind non-inferiority clinical study]. ( Baek, IH; Choi, SC; Choung, RS; Jeen, YT; Kang, SH; Kim, KO; Kim, SY; Kim, YS; Koo, JS; Koo, YS; Lee, JH; Lee, SJ; Moon, JS; Park, JJ; Park, SC, 2013)
"To compare the differences in the therapeutic effect on irritable bowel syndrome (IBS) between acupuncture at Tianshu (ST 25) and Dachangshu (BL 25) and western medication with Trimebutine Maleate."5.15[Comparative study on irritable bowel syndrome treated with acupuncture and western medicine]. ( Lei, MN; Shi, ZM; Wang, QX; Zhu, YS, 2011)
"To observe the efficacy and adverse drug reaction of trimebutine maleate in treating patients with functional dyspepsia (FD) coexisting with diarrhea dominant irritable bowel syndrome (IBS-D)."5.12[A randomized and case-control clinical study on trimebutine maleate in treating functional dyspepsia coexisting with diarrhea-dominant irritable bowel syndrome]. ( Guo, JN; Li, HJ; Lin, YH; Yan, R; Zeng, ZY; Zhong, YQ; Zhu, J, 2007)
"Trimebutine improved symptoms and psychological adjustment to illness in irritable bowel syndrome in comparison with placebo."5.12The effect of trimebutine on the psychosocial adjustment to illness in the irritable bowel syndrome. ( Dumitraşcu, DL; Stănculete, M, 2006)
"Trimebutine maleate has been used extensively, since the late 1960's, for the treatment of functional gastrointestinal disorders, including irritable bowel syndrome (IBS)."5.01Trimebutine: a state-of-the-art review. ( Salvioli, B, 2019)
"Trimebutine maleate, which modulates the calcium and potassium channels, relieves abdominal pain in patients with irritable bowel syndrome."3.76Effectiveness of trimebutine maleate on modulating intestinal hypercontractility in a mouse model of postinfectious irritable bowel syndrome. ( Hou, X; Liu, Y; Long, Y; Qian, W; Tong, J, 2010)
"We examined the effect of ramosetron, a potent serotonin (5-HT)(3)-receptor antagonist for irritable bowel syndrome with diarrhea, on conditioned fear stress (CFS)-induced defecation and normal (non-stressed) defecation in rats and compared ramosetron with the antidiarrheal agent loperamide and the spasmolytic agents trimebutine and tiquizium."3.74Inhibitory effects of ramosetron, a potent and selective 5-HT3-receptor antagonist, on conditioned fear stress-induced abnormal defecation and normal defecation in rats: comparative studies with antidiarrheal and spasmolytic agents. ( Akuzawa, S; Funatsu, T; Hirata, T; Keto, Y; Miyata, K; Sasamata, M, 2008)
"Fenoverine acts as a synchronizer of smooth muscle in modulating the intracellular influx of calcium."2.78[Efficacy of fenoverine and trimebutine in the management of irritable bowel syndrome: multicenter randomized double-blind non-inferiority clinical study]. ( Baek, IH; Choi, SC; Choung, RS; Jeen, YT; Kang, SH; Kim, KO; Kim, SY; Kim, YS; Koo, JS; Koo, YS; Lee, JH; Lee, SJ; Moon, JS; Park, JJ; Park, SC, 2013)
"Trimebutine was prescribed in accordance with the instructions for medical use: orally, 300 mg twice per day for 28 days."1.62[Efficacy of trimebutine in the treatment of functional gastrointestinal disorders: an observational multicenter study]. ( Andreev, DN; Maev, IV, 2021)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's5 (41.67)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Andreev, DN1
Maev, IV1
Makarova, AA2
Diukova, GM2
Ruchkina, IN2
Romashkina, NV2
Indejkina, LK2
Degterev, DA2
Dbar, SR2
Parfenov, AI2
Salvioli, B1
Kang, SH1
Jeen, YT1
Koo, JS1
Koo, YS1
Kim, KO1
Kim, YS1
Kim, SY1
Moon, JS1
Park, JJ1
Baek, IH1
Park, SC1
Lee, SJ1
Lee, JH1
Choung, RS1
Choi, SC1
Rahman, MZ1
Ahmed, DS1
Mahmuduzzaman, M1
Rahman, MA1
Chowdhury, MS1
Barua, R1
Ishaque, SM1
Long, Y1
Liu, Y1
Tong, J1
Qian, W1
Hou, X1
Shi, ZM1
Zhu, YS1
Wang, QX1
Lei, MN1
Kountouras, J1
Zavos, C1
Chatzopoulos, D1
Mearin, F1
Zhong, YQ1
Zhu, J1
Guo, JN1
Yan, R1
Li, HJ1
Lin, YH1
Zeng, ZY1
Hirata, T1
Funatsu, T1
Keto, Y1
Akuzawa, S1
Sasamata, M1
Miyata, K1
Dumitraşcu, DL1
Stănculete, M1

Reviews

2 reviews available for trimebutine and Colitis, Mucous

ArticleYear
Trimebutine: a state-of-the-art review.
    Minerva gastroenterologica e dietologica, 2019, Volume: 65, Issue:3

    Topics: Animals; Digestive System Physiological Phenomena; Gastrointestinal Agents; Gastrointestinal Disease

2019
[Drug treatment of irritable bowel syndrome: an unmet need].
    Gastroenterologia y hepatologia, 2007, Volume: 30, Issue:3

    Topics: Abdominal Pain; Analgesics; Antidepressive Agents, Tricyclic; Antidiarrheals; Carbolines; Controlled

2007

Trials

6 trials available for trimebutine and Colitis, Mucous

ArticleYear
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
    Terapevticheskii arkhiv, 2022, Sep-05, Volume: 94, Issue:2S

    Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser

2022
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
    Terapevticheskii arkhiv, 2022, Sep-05, Volume: 94, Issue:2S

    Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser

2022
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
    Terapevticheskii arkhiv, 2022, Sep-05, Volume: 94, Issue:2S

    Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser

2022
[Visceral sensitivity in diagnostics and treatment of severe irritated bowel syndrome].
    Terapevticheskii arkhiv, 2022, Sep-05, Volume: 94, Issue:2S

    Topics: Adult; Diarrhea; Duloxetine Hydrochloride; Female; Humans; Irritable Bowel Syndrome; Male; Pain; Ser

2022
[Efficacy of fenoverine and trimebutine in the management of irritable bowel syndrome: multicenter randomized double-blind non-inferiority clinical study].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2013, Volume: 62, Issue:5

    Topics: Abdominal Pain; Adult; Constipation; Diarrhea; Double-Blind Method; Drug Administration Schedule; Fe

2013
Comparative efficacy and safety of trimebutine versus mebeverine in the treatment of irritable bowel syndrome.
    Mymensingh medical journal : MMJ, 2014, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Bangladesh; Female; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Pain Mea

2014
[Comparative study on irritable bowel syndrome treated with acupuncture and western medicine].
    Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 2011, Volume: 31, Issue:7

    Topics: Acupuncture Therapy; Adolescent; Adult; Aged; Child; Female; Humans; Irritable Bowel Syndrome; Male;

2011
[A randomized and case-control clinical study on trimebutine maleate in treating functional dyspepsia coexisting with diarrhea-dominant irritable bowel syndrome].
    Zhonghua nei ke za zhi, 2007, Volume: 46, Issue:11

    Topics: Adolescent; Adult; Case-Control Studies; Constipation; Diarrhea; Dyspepsia; Female; Gastrointestinal

2007
The effect of trimebutine on the psychosocial adjustment to illness in the irritable bowel syndrome.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2006, Volume: 44, Issue:3

    Topics: Adaptation, Psychological; Adult; Female; Gastrointestinal Agents; Humans; Irritable Bowel Syndrome;

2006

Other Studies

4 other studies available for trimebutine and Colitis, Mucous

ArticleYear
[Efficacy of trimebutine in the treatment of functional gastrointestinal disorders: an observational multicenter study].
    Terapevticheskii arkhiv, 2021, Aug-15, Volume: 93, Issue:8

    Topics: Abdominal Pain; Dyspepsia; Female; Gastrointestinal Diseases; Humans; Irritable Bowel Syndrome; Male

2021
Effectiveness of trimebutine maleate on modulating intestinal hypercontractility in a mouse model of postinfectious irritable bowel syndrome.
    European journal of pharmacology, 2010, Jun-25, Volume: 636, Issue:1-3

    Topics: Acetylcholine; Animals; Body Weight; Colon; Disease Models, Animal; Dose-Response Relationship, Drug

2010
H pylori infection and reflux oesophagitis.
    Gut, 2004, Volume: 53, Issue:6

    Topics: Cohort Studies; Drug Therapy, Combination; Esophagitis; Gastroesophageal Reflux; Gastrointestinal Ag

2004
Inhibitory effects of ramosetron, a potent and selective 5-HT3-receptor antagonist, on conditioned fear stress-induced abnormal defecation and normal defecation in rats: comparative studies with antidiarrheal and spasmolytic agents.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:2

    Topics: Animals; Antidiarrheals; Benzimidazoles; Conditioning, Classical; Defecation; Fear; Irritable Bowel

2008