trimebutine has been researched along with Abdominal Pain in 5 studies
Trimebutine: Proposed spasmolytic with possible local anesthetic action used in gastrointestinal disorders.
Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fenoverine acts as a synchronizer of smooth muscle in modulating the intracellular influx of calcium." | 6.78 | [Efficacy of fenoverine and trimebutine in the management of irritable bowel syndrome: multicenter randomized double-blind non-inferiority clinical study]. ( Baek, IH; Choi, SC; Choung, RS; Jeen, YT; Kang, SH; Kim, KO; Kim, SY; Kim, YS; Koo, JS; Koo, YS; Lee, JH; Lee, SJ; Moon, JS; Park, JJ; Park, SC, 2013) |
| "Fenoverine acts as a synchronizer of smooth muscle in modulating the intracellular influx of calcium." | 2.78 | [Efficacy of fenoverine and trimebutine in the management of irritable bowel syndrome: multicenter randomized double-blind non-inferiority clinical study]. ( Baek, IH; Choi, SC; Choung, RS; Jeen, YT; Kang, SH; Kim, KO; Kim, SY; Kim, YS; Koo, JS; Koo, YS; Lee, JH; Lee, SJ; Moon, JS; Park, JJ; Park, SC, 2013) |
| "Trimebutine was prescribed in accordance with the instructions for medical use: orally, 300 mg twice per day for 28 days." | 1.62 | [Efficacy of trimebutine in the treatment of functional gastrointestinal disorders: an observational multicenter study]. ( Andreev, DN; Maev, IV, 2021) |
| "Nor-trimebutine has a blocking activity on sodium channels and a potent local anesthetic effect." | 1.33 | Effect of nor-trimebutine on neuronal activation induced by a noxious stimulus or an acute colonic inflammation in the rat. ( Bonaz, B; Mouchet, P; Sinniger, V, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andreev, DN | 1 |
| Maev, IV | 1 |
| Kang, SH | 1 |
| Jeen, YT | 1 |
| Koo, JS | 1 |
| Koo, YS | 1 |
| Kim, KO | 1 |
| Kim, YS | 1 |
| Kim, SY | 1 |
| Moon, JS | 1 |
| Park, JJ | 1 |
| Baek, IH | 1 |
| Park, SC | 1 |
| Lee, SJ | 1 |
| Lee, JH | 1 |
| Choung, RS | 1 |
| Choi, SC | 1 |
| Sinniger, V | 1 |
| Mouchet, P | 1 |
| Bonaz, B | 1 |
| Mearin, F | 1 |
| Matsue, T | 1 |
| Yamato, S | 1 |
| Umeda, N | 1 |
1 review available for trimebutine and Abdominal Pain
| Article | Year |
|---|---|
[Drug treatment of irritable bowel syndrome: an unmet need].
Topics: Abdominal Pain; Analgesics; Antidepressive Agents, Tricyclic; Antidiarrheals; Carbolines; Controlled | 2007 |
1 trial available for trimebutine and Abdominal Pain
| Article | Year |
|---|---|
[Efficacy of fenoverine and trimebutine in the management of irritable bowel syndrome: multicenter randomized double-blind non-inferiority clinical study].
Topics: Abdominal Pain; Adult; Constipation; Diarrhea; Double-Blind Method; Drug Administration Schedule; Fe | 2013 |
3 other studies available for trimebutine and Abdominal Pain
| Article | Year |
|---|---|
[Efficacy of trimebutine in the treatment of functional gastrointestinal disorders: an observational multicenter study].
Topics: Abdominal Pain; Dyspepsia; Female; Gastrointestinal Diseases; Humans; Irritable Bowel Syndrome; Male | 2021 |
Effect of nor-trimebutine on neuronal activation induced by a noxious stimulus or an acute colonic inflammation in the rat.
Topics: Abdominal Pain; Acetic Acid; Anesthetics, Local; Animals; Colitis; Immunohistochemistry; Injections, | 2005 |
[Mechanism of action of trimebutine maleate on gastro-colic reflex in patients with irritable bowel syndrome].
Topics: Abdominal Pain; Adult; Animals; Chronic Disease; Colon; Colonic Diseases, Functional; Female; Humans | 1990 |