Page last updated: 2024-08-22

trilostane and Pregnancy

trilostane has been researched along with Pregnancy in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (41.18)	18.7374
1990's	11 (32.35)	18.2507
2000's	6 (17.65)	29.6817
2010's	3 (8.82)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gao, L; Gu, H; He, P; Li, Y; Liu, J; Ni, X; Sun, Q; You, X	1
Aazzerah, RA; Bishop, CV; Hennebold, JD; Quennoz, LM; Stouffer, RL	1
Hennebold, JD; Peluffo, MC; Stouffer, RL; Young, KA	1
de Gier, J; Galac, S; Kooistra, HS; Okkens, AC; Wolthers, CH	1
Lewis, AW; Randel, RD; Weems, CW; Weems, YS	1
le Roux, PA; van der Spuy, ZM	1
Jacobs, HS; James, VH; Jones, DL; Paintin, DB; Piura, B; van der Spuy, ZM; Wright, CS	1
Dickson, LR; Jawad, MJ; Wilson, EA	1
Jenkin, G; Singh-Asa, P; Thorburn, GD	1
Anzalone, AJ; Bell, MR; Christiansen, RG; Creange, JE; Neumann, HC; Potts, GO; Salvador, UJ; Schane, HP	1
Gemmell, RT; Jenkin, G; Thorburn, GD	1
Mitchell, BF; Powell, WA	1
Kato, K; Makimura, N; Mitsui, C; Seki, K	1
Brennecke, SP; Kraemer, DL; Mitchell, MD; Webb, R	1
Jenkin, G; Robinson, JS; Taylor, MJ; Thorburn, GD	1
Anderson, AB; Turnbull, AC; Webb, R	1
Mitchell, MD; Robinson, JS; Taylor, MJ; Webb, R	1
Lemon, M; Mauléon, P	1
Duffy, DM; Stewart, DR; Stouffer, RL	1
Earnest, KL; Gadsby, JE	1
Holtan, DW; Kerby, JL; Schutzer, WE	1
Duffy, DM; Hutchison, JS; Stewart, DR; Stouffer, RL	1
Hirst, JJ; Nicol, MB; Thorburn, GD; Walker, D	1
Duffy, DM; Stouffer, RL	1
Crossley, KJ; Hirst, JJ; Nicol, MB; Thorburn, GD; Walker, DW	1
Challis, JR; Chwalisz, K; Clifton, VL; Patel, FA	1
Lemme, C; Vincent, DL; Weems, CW; Weems, YS	1
Bridges, PJ; LeaMaster, BR; Vincent, DL; Weems, CW; Weems, YS	1
Bridges, PJ; Ching, L; Kim, L; LeaMaster, BR; Vincent, DL; Weems, CW; Weems, YS	1
Challis, JR; Patel, FA	1
le Roux, PA; Tregoning, SK; van der Spuy, ZM; Zinn, PM	1
Creange, JE; Potts, GO; Schane, HP	1
Katayama, T; Koike, H; Nakada, T	1
Jenkin, G; Thorburn, GD	1

Reviews

1 review(s) available for trilostane and Pregnancy

Article	Year
Oestrogens and parturition. The Journal of endocrinology, 1981, Volume: 89 Suppl Topics: Adrenal Cortex; Androstanols; Animals; Cervix Uteri; Dihydrotestosterone; Estrogens; Female; Fetal Diseases; Glucocorticoids; Humans; Labor, Obstetric; Nitriles; Placenta; Pregnancy; Pregnancy Trimester, Third; Prostaglandins; Sheep; Uterine Contraction	1981

Trials

3 trial(s) available for trilostane and Pregnancy

Article	Year
Effects of the 3β-hydroxysteroid dehydrogenase inhibitor trilostane on luteal progesterone production in the dog. Theriogenology, 2011, Apr-15, Volume: 75, Issue:7 Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Animals; Dihydrotestosterone; Dogs; Enzyme Inhibitors; Female; Luteal Phase; Ovulation; Pregnancy; Progesterone; Prolactin; Time Factors	2011
Labor induction abortion utilizing trilostane, a 3beta-hydroxysteroid dehydrogenase inhibitor. Contraception, 2005, Volume: 71, Issue:5 Topics: 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Adult; Ambulatory Care; Dihydrotestosterone; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Misoprostol; Pregnancy; Pregnancy Trimester, Second; South Africa; Time Factors	2005
Inhibition of progesterone secretion with trilostane for mid-trimester termination of pregnancy: randomized controlled trials. Human reproduction (Oxford, England), 2002, Volume: 17, Issue:6 Topics: 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Adult; Danazol; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Female; Humans; Hydrocortisone; Middle Aged; Misoprostol; Pregnancy; Pregnancy Trimester, Second; Progesterone; Time Factors	2002

Other Studies

30 other study(ies) available for trilostane and Pregnancy

Article	Year
Reduced expression of 15-hydroxy prostaglandin dehydrogenase in chorion during labor is associated with decreased PRB and increased PRA and GR expression. The American journal of pathology, 2013, Volume: 182, Issue:5 Topics: Cells, Cultured; Chorion; Dexamethasone; Dihydrotestosterone; Extraembryonic Membranes; Female; Fluorescent Antibody Technique; Glucocorticoids; Humans; Hydroxyprostaglandin Dehydrogenases; Labor, Obstetric; Pregnancy; Progesterone; Proto-Oncogene Proteins c-jun; Receptors, Glucocorticoid; Receptors, Progesterone; Transcription, Genetic; Trophoblasts; Up-Regulation	2013
Effects of steroid ablation and progestin replacement on the transcriptome of the primate corpus luteum during simulated early pregnancy. Molecular human reproduction, 2014, Volume: 20, Issue:3 Topics: 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents, Steroidal; Animals; Chorionic Gonadotropin; Corpus Luteum; Dihydrotestosterone; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Luteal Phase; Luteinizing Hormone; Macaca mulatta; Pregnancy; Progesterone Congeners; Promegestone; RNA, Messenger; Transcriptome	2014
Expression and regulation of tumor necrosis factor (TNF) and TNF-receptor family members in the macaque corpus luteum during the menstrual cycle. Molecular reproduction and development, 2009, Volume: 76, Issue:4 Topics: Abortifacient Agents, Steroidal; Animals; Corpus Luteum; Dihydrotestosterone; Female; Humans; Macaca; Menstrual Cycle; Pregnancy; Promegestone; Receptors, Tumor Necrosis Factor; RNA, Messenger; Tumor Necrosis Factors	2009
Effects of prostaglandins E2 and F2alpha (PGE2; PGF2alpha), trilostane, mifepristone, palmitic acid (PA), indomethacin (INDO), ethamoxytriphetol (MER-25), PGE2 + PA, or PGF2alpha + PA on PGE2, PGF2alpha, and progesterone secretion by bovine corpora lutea The Chinese journal of physiology, 2002, Dec-31, Volume: 45, Issue:4 Topics: Abortifacient Agents, Steroidal; Animals; Cattle; Corpus Luteum; Dihydrotestosterone; Dinoprost; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Estrogen Antagonists; Ethamoxytriphetol; Female; In Vitro Techniques; Indomethacin; Mifepristone; Oxytocics; Palmitic Acid; Pregnancy; Progesterone; Tocolytic Agents	2002
Inhibition of 3-beta-hydroxy steroid dehydrogenase activity in first trimester human pregnancy with trilostane and WIN 32729. Clinical endocrinology, 1983, Volume: 19, Issue:4 Topics: 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents; Abortifacient Agents, Steroidal; Dehydroepiandrosterone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Pregnancy; Pregnancy Trimester, First; Pregnenolone; Progesterone	1983
Suppression of human chorionic gonadotropin by progestational steroids. American journal of obstetrics and gynecology, 1980, Nov-15, Volume: 138, Issue:6 Topics: Aminoglutethimide; Androgens; Androstanols; Bucladesine; Chorionic Gonadotropin; Dihydrotestosterone; Estrogens; Female; Humans; Hydrocortisone; Nitriles; Organ Culture Techniques; Placenta; Pregnancy; Progestins; Radioimmunoassay	1980
Effects of hydroxysteroid dehydrogenase inhibitors on in-vitro and in-vivo steroidogenesis in the ovine adrenal gland. The Journal of endocrinology, 1982, Volume: 92, Issue:2 Topics: Abortifacient Agents; Abortifacient Agents, Steroidal; Adrenal Glands; Adrenocorticotropic Hormone; Androstenols; Animals; Dihydrotestosterone; Estrus; Female; Hydrocortisone; In Vitro Techniques; Pregnancy; Radioimmunoassay; Sheep	1982
Steroidogenesis inhibitors. 1. Adrenal inhibitory and interceptive activity of trilostane and related compounds. Journal of medicinal chemistry, 1984, Volume: 27, Issue:7 Topics: 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents; Abortifacient Agents, Steroidal; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Corticosterone; Dihydrotestosterone; Female; Macaca mulatta; Magnetic Resonance Spectroscopy; Pregnancy; Progesterone; Pseudopregnancy; Rats; Spectrophotometry, Infrared	1984
Induction of transient functional luteolysis in cyclic sheep by a 3 beta-hydroxysteroid dehydrogenase inhibitor. The Journal of endocrinology, 1984, Volume: 100, Issue:1 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Corpus Luteum; Cytoplasmic Granules; Dihydrotestosterone; Dinoprost; Estrus; Female; Pregnancy; Progesterone; Prostaglandins F; Sheep	1984
Progesterone production by human fetal membranes: an in vitro incubation system for studying hormone production and metabolism. American journal of obstetrics and gynecology, 1984, Feb-01, Volume: 148, Issue:3 Topics: 3-Hydroxysteroid Dehydrogenases; Amnion; Chorion; Decidua; Dihydrotestosterone; Extraembryonic Membranes; Female; Humans; In Vitro Techniques; Pregnancy; Pregnenolone; Progesterone; Radioimmunoassay	1984
Changes in the concentrations of plasma steroid hormone and plasma 13, 14-dihydro-15-oxo-prostaglandin F2 alpha in late pregnancy rabbits treated with an inhibitor of 3 beta-hydroxysteroid dehydrogenase. Endocrinologia japonica, 1984, Volume: 31, Issue:3 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Dihydrotestosterone; Dinoprost; Estradiol; Female; Labor, Obstetric; Pregnancy; Progesterone; Prostaglandins F; Rabbits	1984
Progesterone withdrawal without parturition. European journal of obstetrics, gynecology, and reproductive biology, 1983, Volume: 15, Issue:1 Topics: Animals; Dihydrotestosterone; Dinoprost; Estradiol; Female; Labor, Obstetric; Pregnancy; Progesterone; Prostaglandins F; Sheep	1983
Regulation of ovine placental lactogen: lack of correlation with progesterone secretion. The Journal of endocrinology, 1982, Volume: 95, Issue:2 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Dihydrotestosterone; Female; Placental Lactogen; Pregnancy; Pregnancy, Animal; Progesterone; Sheep; Time Factors	1982
Effect of progesterone withdrawal in sheep during late pregnancy. The Journal of endocrinology, 1982, Volume: 92, Issue:1 Topics: Abortifacient Agents; Abortifacient Agents, Steroidal; Animals; Dihydrotestosterone; Dinoprost; Female; Labor, Obstetric; Pregnancy; Progesterone; Prostaglandins F; Radioimmunoassay; Sheep	1982
Interaction between two luteal cell types from the corpus luteum of the sow in progesterone synthesis in vitro. Journal of reproduction and fertility, 1982, Volume: 64, Issue:2 Topics: Abortifacient Agents, Steroidal; Aminoglutethimide; Animals; Cells, Cultured; Cholesterol; Corpus Luteum; Dihydrotestosterone; Female; Luteal Cells; Perfusion; Pregnancy; Pregnenolone; Progesterone; Swine	1982
Dissociation of relaxin and progesterone secretion from the primate corpus luteum by acute administration of a 3 beta-hydroxysteroid dehydrogenase inhibitor during the menstrual cycle. Biology of reproduction, 1995, Volume: 53, Issue:2 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Chorionic Gonadotropin; Corpus Luteum; Dihydrotestosterone; Enzyme Inhibitors; Female; Kinetics; Luteal Phase; Macaca mulatta; Menstrual Cycle; Pregnancy; Progesterone; Relaxin	1995
Prostaglandin F2 alpha stimulates progesterone secretion by porcine luteal cells in vitro throughout the estrous cycle. Prostaglandins, 1994, Volume: 48, Issue:2 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Calcimycin; Cells, Cultured; Corpus Luteum; Dihydrotestosterone; Dinoprost; Dose-Response Relationship, Drug; Estrus; Female; Pregnancy; Progesterone; Radioimmunoassay; Swine; Tetradecanoylphorbol Acetate; Time Factors	1994
Differential effect of trilostane on the progestin milieu in the pregnant mare. Journal of reproduction and fertility, 1996, Volume: 107, Issue:2 Topics: 3-Hydroxysteroid Dehydrogenases; 5-alpha-Dihydroprogesterone; Animals; Dihydrotestosterone; Female; Horses; Male; Placenta; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Progestins	1996
Stimulation of primate luteal function by recombinant human chorionic gonadotropin and modulation of steroid, but not relaxin, production by an inhibitor of 3 beta-hydroxysteroid dehydrogenase during simulated early pregnancy. The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:6 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Chorionic Gonadotropin; Corpus Luteum; Dihydrotestosterone; Female; Humans; Macaca mulatta; Pregnancy; Pregnancy, Animal; Progesterone; Recombinant Proteins; Relaxin	1996
Effect of alteration of maternal plasma progesterone concentrations on fetal behavioural state during late gestation. The Journal of endocrinology, 1997, Volume: 152, Issue:3 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Arousal; Dihydrotestosterone; Electromyography; Electrooculography; Female; Fetal Blood; Fetus; Gestational Age; Movement; Pregnancy; Pregnancy, Animal; Progesterone; Respiratory Muscles; Sheep	1997
Gonadotropin versus steroid regulation of the corpus luteum of the rhesus monkey during simulated early pregnancy. Biology of reproduction, 1997, Volume: 57, Issue:6 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Chorionic Gonadotropin; Corpus Luteum; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Female; Immunohistochemistry; Lipids; Luteal Phase; Macaca mulatta; Organ Size; Pregnancy; Progesterone; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger	1997
Suppression of arousal by progesterone in fetal sheep. Reproduction, fertility, and development, 1997, Volume: 9, Issue:8 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Arousal; Brain; Dihydrotestosterone; Electromyography; Enzyme Inhibitors; Female; Maternal-Fetal Exchange; Pregnancy; Progesterone; Sheep; Sleep	1997
Steroid regulation of prostaglandin dehydrogenase activity and expression in human term placenta and chorio-decidua in relation to labor. The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:1 Topics: Cells, Cultured; Chorion; Decidua; Dexamethasone; Dihydrotestosterone; Dinoprostone; Female; Humans; Hydrocortisone; Hydroxyprostaglandin Dehydrogenases; Labor, Obstetric; Mifepristone; Placenta; Pregnancy; Progesterone; RNA, Messenger; Steroids; Trophoblasts	1999
Trilostane but not prostaglandin F2alpha (PGF2alpha) or cortisol aborts 90-day-pregnant lutectomized sheep. Prostaglandins & other lipid mediators, 1999, Volume: 58, Issue:2-4 Topics: 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents, Steroidal; Abortion, Induced; Abortion, Veterinary; Animals; Corpus Luteum; Dihydrotestosterone; Dinoprost; Enzyme Inhibitors; Estradiol; Female; Hydrocortisone; Organ Size; Placenta; Pregnancy; Pregnancy, Animal; Progesterone; Sheep; Time Factors	1999
Effect of trilostane on PGE, PGF2alpha, estradiol-17beta, and progesterone secretion and pregnancy of 90-day ovariectomized pregnant ewes. Prostaglandins & other lipid mediators, 1999, Volume: 58, Issue:2-4 Topics: Abortifacient Agents, Steroidal; Abortion, Veterinary; Animals; Dihydrotestosterone; Dinoprost; Female; Ovariectomy; Pregnancy; Pregnancy, Animal; Progesterone; Prostaglandins E; Sheep; Time Factors	1999
Effects of indomethacin, luteinizing hormone (LH), prostaglandin E2 (PGE2), trilostane, mifepristone, ethamoxytriphetol (MER-25) on secretion of prostaglandin E (PGE), prostaglandin F2alpha (PGF2alpha) and progesterone by ovine corpora lutea of pregnancy Prostaglandins & other lipid mediators, 2001, Volume: 63, Issue:4 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Corpus Luteum; Cyclooxygenase Inhibitors; Dihydrotestosterone; Dinoprost; Dinoprostone; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrus; Ethamoxytriphetol; Female; Hormone Antagonists; In Vitro Techniques; Indomethacin; Luteinizing Hormone; Mifepristone; Pregnancy; Progesterone; Prostaglandins E; Sheep	2001
Cortisol/progesterone antagonism in regulation of 15-hydroxysteroid dehydrogenase activity and mRNA levels in human chorion and placental trophoblast cells at term. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:2 Topics: Chorion; Culture Techniques; Dihydrotestosterone; Drug Synergism; Enzyme Inhibitors; Female; Gestational Age; Glucocorticoids; Humans; Hydrocortisone; Hydroxyprostaglandin Dehydrogenases; Medroxyprogesterone Acetate; Placenta; Pregnancy; Progesterone; Progesterone Congeners; Progestins; RNA, Messenger; Trophoblasts	2002
Inhibition of ovarian, placental, and adrenal steroidogenesis in the rhesus monkey by trilostane. Fertility and sterility, 1979, Volume: 32, Issue:4 Topics: 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents; Abortifacient Agents, Steroidal; Adrenal Glands; Androstanes; Animals; Dihydrotestosterone; Female; Haplorhini; Hydrocortisone; Macaca mulatta; Menstruation; Nitriles; Ovary; Placenta; Pregnancy; Progesterone; Steroids	1979
Uneventful delivery following series of successive treatments for virilized Cushing syndrome due to adrenocortical carcinoma. Urology, 1990, Volume: 36, Issue:4 Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Antineoplastic Agents; Cisplatin; Combined Modality Therapy; Cushing Syndrome; Dihydrotestosterone; Female; Humans; Pregnancy	1990
Inhibition of progesterone secretion by a 3 beta-hydroxysteroid dehydrogenase inhibitor in late pregnant sheep. Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:2 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Dihydrotestosterone; Estradiol; Female; Gestational Age; Placental Lactogen; Pregnancy; Pregnancy, Animal; Progesterone; Radioimmunoassay; Sheep; Time Factors	1985