Page last updated: 2024-08-22

trilostane and Breast Neoplasms

trilostane has been researched along with Breast Neoplasms in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (44.44)	18.7374
1990's	3 (16.67)	18.2507
2000's	4 (22.22)	29.6817
2010's	3 (16.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chang, YC; Chen, CK; Chen, MJ; Chen, SN; Cheng, SP; Huang, WC; Lin, CH; Lin, JC; Liu, CL	1
Chang, YC; Chen, SN; Cheng, SP; Lin, CH; Lin, JC; Liu, CL	1
Bucholtz, KM; Kacsoh, B; Mack, VL; Sun, J; Thomas, JL	1
Bucholtz, KM; Mack, VL; Sun, J; Terrell, JR; Thomas, JL	1
Barker, S; Glover, HR; Malouitre, SD; Puddefoot, JR; Vinson, GP	2
Barker, S; Puddefoot, JR; Vinson, GP	1
Carlström, K; Döberl, A; Pousette, A; Rannevik, G; Wilking, N	1
Beardwell, CG; Bu'Lock, D; Hindley, AC; Ribeiro, GG; Todd, ID; Wilkinson, PM	1
Bachelot, F; Barley, VL; Blackledge, GR; Dermaille, A; Fargeot, P; Namer, M; Pouillart, J; Rowland, CG; Tyrrell, CJ; Williams, CJ	1
Barley, VL; Blackledge, GR; Rowland, CG; Tyrrell, CJ; Williams, CJ	1
Everson, LK; Ingle, JN; Krook, JE; Long, HJ; Mailliard, JA; McCormack, GW; Schaid, DJ	1
Buzdar, AU; Chu, PS; Hortobagyi, GN	1
Coune, A; Devleeschouwer, N; Leclercq, G; Nijs, M; Paridaens, R; Tueni, E; Vermeulen, A	1
Barley, V; Blackledge, G; Hutcheon, A; Kaye, S; Keen, C; Rowland, C; Smith, D; Tyrrell, C; Webster, DJ; Williams, CJ	1
Coombes, RC; Easton, D; Goss, PE; Singh, D; Wilkinson, JR; Williams, JC	1
Coombes, RC; Hunt, J; Muindi, J; Neville, AM; Perez, D; Powles, TJ; Ward, M	1
Beardwell, CG; Bu'lock, D; Hindley, AC; St John, J; Wilkinson, PM	1

Reviews

1 review(s) available for trilostane and Breast Neoplasms

Article	Year
Trilostane in advanced breast cancer. Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:17 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Dihydrotestosterone; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Hormone-Dependent; Postmenopause; Rats	2006

Trials

3 trial(s) available for trilostane and Breast Neoplasms

Article	Year
Multicentre cross-over study of aminoglutethimide and trilostane in advanced postmenopausal breast cancer. Clinical oncology (Royal College of Radiologists (Great Britain)), 1995, Volume: 7, Issue:2 Topics: Administration, Oral; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cross-Over Studies; Dihydrotestosterone; Drug Administration Schedule; Female; Humans; Middle Aged; Postmenopause; Treatment Outcome	1995
Multicentre cross over study of aminoglutethimide and trilostane in advanced postmenopausal breast cancer. British journal of cancer, 1993, Volume: 68, Issue:6 Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Aged; Aminoglutethimide; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Dihydrotestosterone; Drug Resistance; Estrogen Antagonists; Female; Humans; Hydrocortisone; Lyases; Menopause; Middle Aged; Treatment Outcome	1993
Trilostane with hydrocortisone in treatment of metastatic breast cancer. Breast cancer research and treatment, 1989, Volume: 13, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Dihydrotestosterone; Female; Humans; Hydrocortisone; Middle Aged; Nausea; Neoplasm Metastasis; Prospective Studies; Vomiting	1989

Other Studies

14 other study(ies) available for trilostane and Breast Neoplasms

Article	Year
Expression of 3β-Hydroxysteroid Dehydrogenase Type 1 in Breast Cancer is Associated with Poor Prognosis Independent of Estrogen Receptor Status. Annals of surgical oncology, 2017, Volume: 24, Issue:13 Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Cycle; Cell Movement; Cell Proliferation; Dihydrotestosterone; Female; Follow-Up Studies; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Multienzyme Complexes; Progesterone Reductase; Prognosis; Receptors, Estrogen; RNA, Small Interfering; Steroid Isomerases; Survival Rate; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2017
Inhibition of 3β-Hydroxysteroid Dehydrogenase Type 1 Suppresses Interleukin-6 in Breast Cancer. The Journal of surgical research, 2019, Volume: 241 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dihydrotestosterone; Drug Synergism; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Interleukin-6; Multienzyme Complexes; Oligonucleotide Array Sequence Analysis; Paclitaxel; Progesterone Reductase; Recombinant Proteins; RNA, Small Interfering; Steroid Isomerases	2019
Structural basis for the selective inhibition of human 3beta-hydroxysteroid dehydrogenase 1 in human breast tumor MCF-7 cells. Molecular and cellular endocrinology, 2009, Mar-25, Volume: 301, Issue:1-2 Topics: 3-Hydroxysteroid Dehydrogenases; Arginine; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Coenzymes; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Mutant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substrate Specificity	2009
The functions of key residues in the inhibitor, substrate and cofactor sites of human 3beta-hydroxysteroid dehydrogenase type 1 are validated by mutagenesis. The Journal of steroid biochemistry and molecular biology, 2010, Volume: 120, Issue:4-5 Topics: 3-Hydroxysteroid Dehydrogenases; Amino Acids; Binding Sites; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Substrate Specificity	2010
Non-competitive steroid inhibition of oestrogen receptor functions. International journal of cancer, 2002, Sep-01, Volume: 101, Issue:1 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Dihydrotestosterone; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Protein Isoforms; Rats; Rats, Wistar; Receptors, Estrogen; Response Elements; Transcription, Genetic; Tumor Cells, Cultured	2002
Comparison of effects of 4-hydroxy tamoxifen and trilostane on oestrogen-regulated gene expression in MCF-7 cells: up-regulation of oestrogen receptor beta. The Journal of steroid biochemistry and molecular biology, 2006, Volume: 100, Issue:4-5 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Estrogen Antagonists; Estrogen Receptor beta; Estrogens; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Tamoxifen; Up-Regulation	2006
Inhibition of steroid sulfatase activity by danazol. Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 123 Topics: Aminoglutethimide; Breast Neoplasms; Carcinoma; Culture Techniques; Danazol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estrogen Antagonists; Estrone; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Pregnadienes; Tamoxifen	1984
Trilostane in the treatment of advanced breast cancer. Cancer chemotherapy and pharmacology, 1983, Volume: 10, Issue:3 Topics: Antineoplastic Agents; Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Middle Aged; Neoplasm Metastasis	1983
Evaluation of trilostane plus hydrocortisone in women with metastatic breast cancer and prior hormonal therapy exposure. American journal of clinical oncology, 1990, Volume: 13, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dihydrotestosterone; Female; Hormones; Humans; Hydrocortisone; Middle Aged; Neoplasm Metastasis; Remission Induction	1990
Endocrine effects of Trilostane: in vitro and in vivo studies. European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:10 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Dihydrotestosterone; Female; Hormones; Humans; Hydrocortisone; Receptors, Cell Surface; Tumor Cells, Cultured	1987
Multicenter study of trilostane: a new hormonal agent in advanced postmenopausal breast cancer. Cancer treatment reports, 1987, Volume: 71, Issue:12 Topics: Breast Neoplasms; Carcinoma; Dexamethasone; Dihydrotestosterone; Female; Humans; Menopause; Multi-Institutional Systems	1987
Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response. Cancer research, 1986, Volume: 46, Issue:9 Topics: Aminoglutethimide; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Dihydrotestosterone; Female; Humans; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Ovariectomy; Rats; Tamoxifen	1986
Trilostane therapy for advanced breast cancer. Cancer treatment reports, 1985, Volume: 69, Issue:4 Topics: Aged; Breast Neoplasms; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Hydrocortisone; Menopause; Middle Aged; Receptors, Estrogen	1985
Hormonal changes in postmenopausal women with breast cancer treated with trilostane and dexamethasone. Clinical endocrinology, 1985, Volume: 23, Issue:4 Topics: Adrenal Cortex Hormones; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Estrone; Female; Gonadal Steroid Hormones; Humans; Menopause; Neoplasm Metastasis	1985