Page last updated: 2024-08-22

trilostane and Adrenocortical Hyperfunction

trilostane has been researched along with Adrenocortical Hyperfunction in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's22 (40.74)29.6817
2010's23 (42.59)24.3611
2020's9 (16.67)2.80

Authors

AuthorsStudies
Aniballi, C; Barbarossa, A; de Marco, V; Fracassi, F; Galac, S; Golinelli, S; Leal, RO; Maietti, E; Tardo, AM1
Alonso-Miguel, D; Arenas Bermejo, C; Clares Moral, I; García San José, P; González Sanz, S; Pérez-Alenza, MD; Portero Fuentes, M1
Cadoré, JL; Chabanne, L; Hugonnard, M; Krafft, E; Lamoureux, A1
Brodbelt, DC; Church, D; Niessen, S; O'Neill, D; Schofield, I; Wilson, ARL1
Alonso-Miguel, D; Arenas Bermejo, C; Clares Moral, I; Cuesta-Alvaro, P; García San José, P; Pérez Alenza, MD1
Kim, KB; Park, SM; Song, WJ; Youn, HY1
Feldman, EC; Kim, TW; Nam, S; Seo, KW; Song, KH1
Appleman, E; Lamb, KE; Langston, C; Schrage, A1
Ballhausen, D; Glöckner, S; Hartmann, K; Stockhaus, C; Wehner, A; Weiss, B; Zablotski, Y1
Brown, S; Crosby, J1
King, JB; Morton, JM1
Blois, S; Lemetayer, J1
Swieton, N1
Griffies, JD1
Akiyama, R; Azakami, D; Ishioka, K; Maruyama, N; Momota, Y; Mori, A; Murata, A; Nozawa, S; Oda, H; Saeki, K; Sako, T; Shono, S; Tazaki, H; Ueda, K1
Nagata, N; Yuki, M1
Mori, A; Oda, H; Onozawa, E; Sako, T; Shono, S1
Aldridge, C; Behrend, EN; Bruyette, D; Gaillard, P; Kemppainen, RJ; Lee, HP; Lee-Fowler, TM; Martin, LG; Pannu, J; Ward, CR1
Boretti, FS; Holzthüm, J; Reusch, CE; Sieber-Ruckstuhl, NS1
Chang, D; Chang, J; Kang, JH; Kim, HS; Noh, S; Yang, MP1
Macfarlane, L; Parkin, T; Ramsey, I1
Koyama, H; Matsumoto, H; Okusa, T; Teshima, T; Uchiyama, R1
Hickey, JM; Le Roux, AB; Noel, PG1
Kojima, K; Nagata, N; Yuki, M1
Begon, D; Benchekroun, G; de Fornel-Thibaud, P; Delisle, F; Gomez, E; Héripret, D; Lafarge, S; Maurey, C; Moraillon, R; Rosenberg, D1
Boretti, FS; Maser-Gluth, C; Reusch, CE; Sieber-Ruckstuhl, NS; Wenger, M2
Irwin, PJ; Lenard, Z; Ramsey, IK; Richardson, J; Tebb, AJ1
Ramsey, IK1
Bond, KG; Cook, AK1
Augusto, M; Helm, J; Knottenbelt, C; McGrotty, Y; McLauchlan, G; Ramsey, I1
Aldajarov, N; Boretti, FS; Burkhardt, WA; Guscetti, F; Ivos Todesco, A; Lutz, TA; Reusch, CE; Sieber-Ruckstuhl, NS1
Behrend, EN; Boothe, DM; Lee, HP; McGraw, AL; Whitley, EM1
Feldman, EC1
Cross, E; Moreland, R; Wallack, S1
Augusto, M; Burden, A; Neiger, R; Ramsey, I1
Eastwood, JM; Elwood, CM; Hurley, KJ1
Nicholls, PK; Petrus, D; Skelly, BJ1
Braddock, JA; Church, DB; Robertson, ID; Watson, AD1
Neiger, R; Witt, AL1
Boag, AK; Church, DB; Neiger, R1
Archer, J; Brockman, DJ; Chapman, PS; Kelly, DF; Neiger, R1
Müller, C; Reusch, CE; Sieber-Ruckstuhl, NS; Wenger, M1
Arteaga, A; Eckersall, PD; Knottenbelt, CM; McGrotty, YL; Ramsey, IK1
Arteaga, A; Evans, H; Ramsey, IK; Tebb, AJ1
Bell, R; McGrotty, Y; Neiger, R; Ramsey, IK1
Behrend, EN1
Lutz, H; Perren, A; Pospischil, A; Reusch, CE; Sieber-Ruckstuhl, N; Wenger, M1
Reine, NJ1
Brown, CG; Graves, TK1
Arenas, C; Clemente, M; De Andrés, PJ; Melián, C; Morales, M; Pérez-Alenza, MD1
Kenefick, SJ; Neiger, R1
Feldman, EC; Hoar, BR; Nelson, RW; Vaughan, MA1
Nett, CS; Reusch, CE; Ruckstuhl, NS1

Reviews

5 review(s) available for trilostane and Adrenocortical Hyperfunction

ArticleYear
Update on the use of trilostane in dogs.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2018, Volume: 59, Issue:4

    Topics: Adrenocortical Hyperfunction; Alopecia; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Pituitary ACTH Hypersecretion

2018
Feline pituitary-dependent hyperadrenocorticism and insulin resistance due to a plurihormonal adenoma.
    Topics in companion animal medicine, 2012, Volume: 27, Issue:1

    Topics: Adrenocortical Hyperfunction; Animals; Antineoplastic Agents; Cat Diseases; Cats; Dihydrotestosterone; Fatal Outcome; Female; Insulin Resistance; Pituitary Gland; Pituitary Neoplasms

2012
Update on drugs used to treat endocrine diseases in small animals.
    The Veterinary clinics of North America. Small animal practice, 2006, Volume: 36, Issue:5

    Topics: Adrenocortical Hyperfunction; Animals; Antithyroid Agents; Cat Diseases; Cats; Diabetes Mellitus; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Hyperthyroidism; Hypoglycemic Agents; Insulin, Long-Acting; Methimazole

2006
Medical management of pituitary-dependent hyperadrenocorticism: mitotane versus trilostane.
    Clinical techniques in small animal practice, 2007, Volume: 22, Issue:1

    Topics: Adrenocortical Hyperfunction; Animals; Antineoplastic Agents, Hormonal; Dihydrotestosterone; Dog Diseases; Dogs; Mitotane; Safety; Treatment Outcome

2007
Hyperadrenocorticism: treating dogs.
    Compendium (Yardley, PA), 2007, Volume: 29, Issue:3

    Topics: Adrenal Cortex Function Tests; Adrenalectomy; Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Drug Therapy, Combination; Ketoconazole; Mitotane; Prognosis; Treatment Outcome

2007

Trials

4 trial(s) available for trilostane and Adrenocortical Hyperfunction

ArticleYear
Comparison of 2 Doses for ACTH Stimulation Testing in Dogs Suspected of or Treated for Hyperadrenocorticism.
    Journal of veterinary internal medicine, 2016, Volume: 30, Issue:5

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Antineoplastic Agents; Case-Control Studies; Cosyntropin; Dihydrotestosterone; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Hormones; Hydrocortisone; Male; Mitotane

2016
A comparison of once and twice daily administration of trilostane to dogs with hyperadrenocorticism.
    Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere, 2012, Volume: 40, Issue:6

    Topics: Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Retrospective Studies; Treatment Outcome

2012
Trilostane treatment in dogs with pituitary-dependent hyperadrenocorticism.
    Australian veterinary journal, 2003, Volume: 81, Issue:10

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Drug Administration Schedule; Enzyme Inhibitors; Female; Hydrocortisone; Male; Prospective Studies; Treatment Outcome

2003
Canine hyperadrenocorticism: effects of trilostane on parathyroid hormone, calcium and phosphate concentrations.
    The Journal of small animal practice, 2005, Volume: 46, Issue:11

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenocortical Hyperfunction; Animals; Calcium; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Hyperparathyroidism, Secondary; Male; Oxidative Phosphorylation Coupling Factors; Parathyroid Hormone; Phosphates

2005

Other Studies

45 other study(ies) available for trilostane and Adrenocortical Hyperfunction

ArticleYear
Comparison of methods to monitor dogs with hypercortisolism treated with trilostane.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:6

    Topics: Adrenocortical Hyperfunction; Animals; Cross-Sectional Studies; Cushing Syndrome; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Hydrocortisone; Prospective Studies

2021
Survival of dogs with pituitary-dependent hyperadrenocorticism treated twice daily with low doses of trilostane.
    The Veterinary record, 2022, Volume: 191, Issue:3

    Topics: Adrenocortical Hyperfunction; Animals; Calcinosis; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Hydrocortisone; Retrospective Studies

2022
Iatrogenic symptomatic hypoadrenocorticism after treatment with trilostane for hyperadrenocorticism in dogs: eight cases (2008-2019).
    The Journal of small animal practice, 2023, Volume: 64, Issue:6

    Topics: Adrenal Insufficiency; Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Hydrocortisone

2023
Survival analysis of 219 dogs with hyperadrenocorticism attending primary care practice in England.
    The Veterinary record, 2020, Mar-21, Volume: 186, Issue:11

    Topics: Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; England; Female; Male; Primary Health Care; Prognosis; Retrospective Studies; Survival Analysis

2020
Changes in systolic blood pressure in dogs with pituitary dependent hyperadrenocorticism during the first year of trilostane treatment.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:1

    Topics: Adrenocortical Hyperfunction; Animals; Blood Pressure; Dihydrotestosterone; Dog Diseases; Dogs; Hypertension; Prospective Studies

2021
Successful treatment of occult hyperadrenocorticism with mitotane but not trilostane in a dog.
    Veterinary medicine and science, 2021, Volume: 7, Issue:4

    Topics: Adrenocortical Hyperfunction; Animals; Antineoplastic Agents; Dihydrotestosterone; Dog Diseases; Dogs; Female; Mitotane; Republic of Korea

2021
Evaluation of compounded trilostane packets for dogs with naturally occurring hyperadrenocorticism.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:4

    Topics: Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Europe; Hydrocortisone; Republic of Korea; United Kingdom

2021
Evaluation of Iatrogenic Hypocortisolemia Following Trilostane Therapy in 48 Dogs with Pituitary-Dependent Hyperadrenocorticism.
    Journal of the American Animal Hospital Association, 2021, Sep-01, Volume: 57, Issue:5

    Topics: Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Hydrocortisone; Iatrogenic Disease; Retrospective Studies

2021
Association between ACTH stimulation test results and clinical signs in dogs with hyperadrenocorticism treated with trilostane.
    Veterinary journal (London, England : 1997), 2021, Volume: 276

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Dihydrotestosterone; Dog Diseases; Dogs

2021
Stability of compounded trilostane suspension in cod liver oil.
    Veterinary journal (London, England : 1997), 2017, Volume: 228

    Topics: Adrenocortical Hyperfunction; Animals; Cod Liver Oil; Dihydrotestosterone; Dog Diseases; Dogs; Drug Stability; Suspensions

2017
Incidence and risk factors for hypoadrenocorticism in dogs treated with trilostane.
    Veterinary journal (London, England : 1997), 2017, Volume: 230

    Topics: Adrenal Cortex Diseases; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Incidence; Risk Factors

2017
Urinary calculi in a shih tzu dog with hyperadrenocorticism.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2018, Volume: 59, Issue:8

    Topics: Adrenocortical Hyperfunction; Animals; Cystotomy; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Urinary Calculi

2018
Old or new? A comparison of mitotane and trilostane for the management of hyperadrenocorticism.
    Compendium (Yardley, PA), 2013, Volume: 35, Issue:5

    Topics: Adrenocortical Hyperfunction; Animals; Antineoplastic Agents, Hormonal; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Mitotane

2013
Decreased gene expressions of insulin signal molecules in canine hyperadrenocorticism.
    The Journal of veterinary medical science, 2014, Volume: 76, Issue:8

    Topics: Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; DNA Primers; Dog Diseases; Dogs; Female; Gene Expression Regulation; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoenzymes; Male; Neutrophils; Phosphatidylinositol 3-Kinase; Protein Kinase C; Proto-Oncogene Proteins c-akt; Statistics, Nonparametric

2014
Long-term outcome of myotonia associated with hyperadrenocorticism in 2 dogs.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2015, Volume: 56, Issue:9

    Topics: Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Fatal Outcome; Female; Muscular Diseases

2015
The effect of 1 year of trilostane treatment on peripheral lymphocyte subsets in dogs with pituitary-dependent hyperadrenocorticism.
    The Journal of veterinary medical science, 2016, Jun-01, Volume: 78, Issue:5

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Dihydrotestosterone; Dog Diseases; Dogs; Female; Hydrocortisone; Lymphocyte Subsets; Male; Steroid Synthesis Inhibitors; Time Factors

2016
Lack of association between clinical signs and laboratory parameters in dogs with hyperadrenocorticism before and during trilostane treatment.
    Schweizer Archiv fur Tierheilkunde, 2016, Volume: 158, Issue:9

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Hydrocortisone; Surveys and Questionnaires

2016
Serum cholecystokinin concentrations in dogs with naturally acquired pituitary-dependent hyperadrenocorticism.
    American journal of veterinary research, 2016, Volume: 77, Issue:10

    Topics: Adrenocortical Hyperfunction; Animals; Case-Control Studies; Cholecystokinin; Cholesterol; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Gallbladder Diseases; Hydrocortisone; Male

2016
Pre-trilostane and three-hour post-trilostane cortisol to monitor trilostane therapy in dogs.
    The Veterinary record, 2016, Dec-10, Volume: 179, Issue:23

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Diagnostic Techniques, Endocrine; Dihydrotestosterone; Dog Diseases; Dogs; Female; Hydrocortisone; Male; Prospective Studies; Reproducibility of Results; Surveys and Questionnaires

2016
Carbenoxolone Disodium Treatment for Canine Pituitary-Dependent Hyperadrenocorticism.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Carbenoxolone; Dihydrotestosterone; Dog Diseases; Dogs; Female; Glucocorticoids; Hydrocortisone; Male; Pituitary ACTH Hypersecretion; Pituitary Gland

2016
What Is Your Diagnosis?
    Journal of the American Veterinary Medical Association, 2016, Dec-15, Volume: 249, Issue:12

    Topics: Adrenal Insufficiency; Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Glucocorticoids

2016
Comparison of Survival Times for Dogs with Pituitary-Dependent Hyperadrenocorticism in a Primary-Care Hospital: Treated with Trilostane versus Untreated.
    Journal of veterinary internal medicine, 2017, Volume: 31, Issue:1

    Topics: Adrenocortical Hyperfunction; Animals; Cohort Studies; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Hospitals, Animal; Japan; Male; Medical Records; Primary Health Care; Retrospective Studies; Survival Analysis

2017
Trilostane therapy for hyperadrenocorticism in three dogs with adrenocortical metastasis.
    The Veterinary record, 2008, Aug-09, Volume: 163, Issue:6

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dogs; Lung Neoplasms; Retrospective Studies

2008
Serum concentrations of cortisol and cortisone in healthy dogs and dogs with pituitary-dependent hyperadrenocorticism treated with trilostane.
    The Veterinary record, 2008, Oct-18, Volume: 163, Issue:16

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Case-Control Studies; Cortisone; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Hormones; Hydrocortisone; Male; Pituitary Diseases; Pituitary Gland; Statistics, Nonparametric

2008
Persistent isolated hypocortisolism following brief treatment with trilostane.
    Australian veterinary journal, 2008, Volume: 86, Issue:12

    Topics: Adrenal Insufficiency; Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Hydrocortisone; Male

2008
Trilostane in dogs.
    The Veterinary clinics of North America. Small animal practice, 2010, Volume: 40, Issue:2

    Topics: Acute-Phase Proteins; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Animals; Creatinine; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Haptoglobins; Thyroid Hormones

2010
Evaluation of the use of baseline cortisol concentration as a monitoring tool for dogs receiving trilostane as a treatment for hyperadrenocorticism.
    Journal of the American Veterinary Medical Association, 2010, Oct-01, Volume: 237, Issue:7

    Topics: Adrenocortical Hyperfunction; Animals; Biomarkers; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Hydrocortisone

2010
Retrospective evaluation of the effect of trilostane on insulin requirement and fructosamine concentration in eight diabetic dogs with hyperadrenocorticism.
    The Journal of small animal practice, 2010, Volume: 51, Issue:12

    Topics: Adrenocortical Hyperfunction; Animals; Diabetes Mellitus; Dihydrotestosterone; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fructosamine; Hypoglycemic Agents; Insulin; Male; Retrospective Studies

2010
Adrenocorticotropic hormone, but not trilostane, causes severe adrenal hemorrhage, vacuolization, and apoptosis in rats.
    Domestic animal endocrinology, 2011, Volume: 40, Issue:3

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Apoptosis; Body Weight; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Immunohistochemistry; Male; Necrosis; Nucleosomes; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric

2011
Determination of the concentrations of trilostane and ketotrilostane that inhibit ex vivo canine adrenal gland synthesis of cortisol, corticosterone, and aldosterone.
    American journal of veterinary research, 2011, Volume: 72, Issue:5

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Aldosterone; Animals; Corticosterone; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Hydrocortisone; In Vitro Techniques; Potassium

2011
Evaluation of twice-daily lower-dose trilostane treatment administered orally in dogs with naturally occurring hyperadrenocorticism.
    Journal of the American Veterinary Medical Association, 2011, Jun-01, Volume: 238, Issue:11

    Topics: Administration, Oral; Adrenocortical Hyperfunction; Animals; Antineoplastic Agents; Dihydrotestosterone; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Male; Treatment Outcome

2011
Trilostane treatment of a dog with functional adrenocortical neoplasia.
    The Journal of small animal practice, 2003, Volume: 44, Issue:3

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Antineoplastic Agents; Blood Chemical Analysis; Dihydrotestosterone; Dog Diseases; Dogs; Female; Radiography; Ultrasonography

2003
Use of trilostane for the treatment of pituitary-dependent hyperadrenocorticism in a cat.
    The Journal of small animal practice, 2003, Volume: 44, Issue:6

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenocortical Hyperfunction; Animals; Candidiasis; Cat Diseases; Cats; Death, Sudden; Diagnosis, Differential; Dihydrotestosterone; Enzyme Inhibitors; Male; Pituitary Neoplasms; Renal Insufficiency

2003
Adrenocorticotropic hormone levels in dogs with pituitary-dependent hyperadrenocorticism following trilostane therapy.
    The Veterinary record, 2004, Mar-27, Volume: 154, Issue:13

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Pituitary Gland; Treatment Outcome

2004
Trilostane treatment of bilateral adrenal enlargement and excessive sex steroid hormone production in a cat.
    The Journal of small animal practice, 2004, Volume: 45, Issue:5

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenocortical Hyperfunction; Animals; Cat Diseases; Cats; Diagnosis, Differential; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Female; Testosterone; Ultrasonography

2004
Adrenal necrosis in a dog receiving trilostane for the treatment of hyperadrenocorticism.
    The Journal of small animal practice, 2004, Volume: 45, Issue:6

    Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Gland Diseases; Adrenocortical Hyperfunction; Animals; Diagnosis, Differential; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Male; Necrosis; Oxidative Phosphorylation Coupling Factors

2004
Effect of trilostane on serum concentrations of aldosterone, cortisol, and potassium in dogs with pituitary-dependent hyperadrenocorticism.
    American journal of veterinary research, 2004, Volume: 65, Issue:9

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; Analysis of Variance; Animals; Blood Chemical Analysis; Dihydrotestosterone; Dog Diseases; Dogs; Hydrocortisone; Potassium; Time Factors

2004
Haptoglobin concentrations in dogs undergoing trilostane treatment for hyperadrenocorticism.
    Veterinary clinical pathology, 2005, Volume: 34, Issue:3

    Topics: Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Haptoglobins; Reference Values

2005
Cortisol, aldosterone, cortisol precursor, androgen and endogenous ACTH concentrations in dogs with pituitary-dependant hyperadrenocorticism treated with trilostane.
    Domestic animal endocrinology, 2006, Volume: 31, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldosterone; Androstenedione; Animals; Cortodoxone; Dehydroepiandrosterone; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Hydrocortisone; Male; Prospective Studies; Statistics, Nonparametric

2006
Study of the effects of once daily doses of trilostane on cortisol concentrations and responsiveness to adrenocorticotrophic hormone in hyperadrenocorticoid dogs.
    The Veterinary record, 2006, Aug-26, Volume: 159, Issue:9

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Drug Administration Schedule; Enzyme Inhibitors; Female; Hydrocortisone; Male; Treatment Outcome

2006
Histological evaluation of the adrenal glands of seven dogs with hyperadrenocorticism treated with trilostane.
    The Veterinary record, 2007, Feb-17, Volume: 160, Issue:7

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Apoptosis; Dihydrotestosterone; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hydrocortisone; In Situ Nick-End Labeling; Male; Treatment Outcome

2007
Comparison of non-selective adrenocorticolysis with mitotane or trilostane for the treatment of dogs with pituitary-dependent hyperadrenocorticism.
    The Veterinary record, 2007, Dec-15, Volume: 161, Issue:24

    Topics: Adrenocortical Hyperfunction; Age Factors; Animals; Antineoplastic Agents, Hormonal; Body Weight; Dihydrotestosterone; Dog Diseases; Dogs; Female; Kaplan-Meier Estimate; Male; Mitotane; Proportional Hazards Models; Treatment Outcome

2007
The effect of trilostane treatment on circulating thyroid hormone concentrations in dogs with pituitary-dependent hyperadrenocorticism.
    The Journal of small animal practice, 2008, Volume: 49, Issue:3

    Topics: Adrenocortical Hyperfunction; Animals; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Male; Reference Values; Thyroid Hormones; Thyrotropin; Thyroxine; Treatment Outcome

2008
Evaluation of twice-daily, low-dose trilostane treatment administered orally in dogs with naturally occurring hyperadrenocorticism.
    Journal of the American Veterinary Medical Association, 2008, May-01, Volume: 232, Issue:9

    Topics: Administration, Oral; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Blood Chemical Analysis; Dihydrotestosterone; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Male; Prospective Studies; Time Factors; Treatment Outcome

2008
Results of clinical examinations, laboratory tests, and ultrasonography in dogs with pituitary-dependent hyperadrenocorticism treated with trilostane.
    American journal of veterinary research, 2002, Volume: 63, Issue:4

    Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Blood Cell Count; Blood Chemical Analysis; Dihydrotestosterone; Dog Diseases; Dogs; Enzyme Inhibitors; Female; Hydrocortisone; Male; Pituitary Diseases; Polyuria; Prospective Studies; Ultrasonography

2002