triiodothyronine has been researched along with Uremia in 29 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To ascertain if excessive protein catabolism is a feature of uremia, we determined leucine flux and nitrogen balance in 11 stable chronic dialysis patients and in 7 normal subjects." | 7.67 | Augmentation of protein degradation by L-triiodothyronine in uremia. ( Flanigan, MJ; Lim, VS; Tsalikian, E, 1989) |
| "ātients with end-stage chronic renal failure (CRF) and those receiving dialysis therapy have normal or decreased serum total T4 (TT4), reduced serum total T3 (TT3), and normal total reverse T3 (TrT3) levels." | 5.27 | Alterations of serum reverse triiodothyronine and thyroxine kinetics in chronic renal failure: role of nutritional status, chronic illness, uremia, and hemodialysis. ( Feinstein, EI; Kaptein, EM; Massry, SG; Nicoloff, JT, 1983) |
| " The present study evaluated triiodothyronine (T3), thyroxine, and thyroid-stimulating hormone concentrations before and early after transplantation relative to the occurrence of delayed graft function." | 3.77 | Protective effect of low serum thyroid hormone concentration on occurrence of functional delayed kidney allograft function early after transplantation. ( Bonakdaran, S; Hekmat, R; Javadi, Z; Javain, ML, 2011) |
| "Although the serum thyroxine (T4) and triiodothyronine (T3) concentrations of uremic rats are commensurate with moderate hypothyroidism, their thyroid status at the tissue level remains controversial." | 3.68 | The hepatocellular thyroid status of uremic rats estimated from the abundances of thyroid hormone-dependent nucleoplasmic proteins. ( Barsano, CP; Dunn, RB; Iqbal, Z; Muñoz, BE; Pullen, GL; Quintanilla, A, 1991) |
| "To ascertain if excessive protein catabolism is a feature of uremia, we determined leucine flux and nitrogen balance in 11 stable chronic dialysis patients and in 7 normal subjects." | 3.67 | Augmentation of protein degradation by L-triiodothyronine in uremia. ( Flanigan, MJ; Lim, VS; Tsalikian, E, 1989) |
| "The main objective of this study was to determine whether the principal abnormality of thyroid function observed in patients with chronic renal failure, low serum triiodothyronine (T(3)) concentration, causes hypothyroidism at the tissue level." | 3.66 | Thyroid function in a uremic rat model. Evidence suggesting tissue hypothyroidism. ( Henriquez, C; Lim, VS; Martino, E; Refetoff, S; Seo, H, 1980) |
| " We have, therefore, investigated the serum concentrations of total thyroxine (T4), total T3 and total 3,3',5'-triiodothyronine (reverse T3)--the metabolically-inactive metabolite of thyroxine--and of TSH in 13 patients with acute myocardial infarction, in 12 patients with compensated liver cirrhosis, in 9 patients with decompensated liver cirrhosis and in 15 patients with chronic renal failure on chronic intermittent haemodialysis by radioimmunoassay." | 3.66 | [Serum concentrations of thyroid hormones in severe non-thyroidal illnesses (author's transl)]. ( Fritzsche, H; Kolbe, H; Seyfried, H; Stummvoll, HK; Weissel, M; Wolf, A, 1978) |
| "Ipodate treatment, on the other hand, resulted in a reduction of serum total T3 to 102 +/- 21 ng/dl, an increase in total T4 to 9." | 2.66 | Blunted peripheral tissue responsiveness to thyroid hormone in uremic patients. ( Flanigan, MJ; Freeman, RM; Lim, VS; Zavala, DC, 1987) |
| "ātients with end-stage chronic renal failure (CRF) and those receiving dialysis therapy have normal or decreased serum total T4 (TT4), reduced serum total T3 (TT3), and normal total reverse T3 (TrT3) levels." | 1.27 | Alterations of serum reverse triiodothyronine and thyroxine kinetics in chronic renal failure: role of nutritional status, chronic illness, uremia, and hemodialysis. ( Feinstein, EI; Kaptein, EM; Massry, SG; Nicoloff, JT, 1983) |
| "Patients with chronic renal failure not on dialysis, have mean serum thyroxine levels similar to normal subjects and low mean serum triiodothyronine levels." | 1.26 | Thyroid dysfunction in uremia: evidence for thyroid and hypophyseal abnormalities. ( Bloomer, HA; Jubiz, W; O'Neill, W; Ramirez, G, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (72.41) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 2 (6.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amato, AA | 1 |
| Santos, GM | 1 |
| Neves, Fde A | 1 |
| Hekmat, R | 1 |
| Javadi, Z | 1 |
| Javain, ML | 1 |
| Bonakdaran, S | 1 |
| Querci, G | 1 |
| Galli, G | 1 |
| Piaggi, P | 1 |
| Rosellini, V | 1 |
| Giannetti, M | 1 |
| Luchetti, F | 1 |
| Donadio, C | 1 |
| Tognotti, D | 1 |
| Caravelli, P | 1 |
| Vitti, P | 1 |
| Grasso, L | 1 |
| Pinchera, A | 1 |
| Santini, F | 1 |
| Blackman, MR | 1 |
| Weintraub, BD | 1 |
| Kourides, IA | 1 |
| Solano, JT | 1 |
| Santner, T | 1 |
| Rosen, SW | 1 |
| Thompson, P | 1 |
| Burman, KD | 1 |
| Lukes, YG | 1 |
| McNeil, JS | 1 |
| Jackson, BD | 1 |
| Latham, KR | 1 |
| Wartofsky, L | 1 |
| Lim, VS | 4 |
| Passo, C | 1 |
| Murata, Y | 1 |
| Ferrari, E | 1 |
| Nakamura, H | 1 |
| Refetoff, S | 2 |
| Kinlaw, WB | 1 |
| Schwartz, HL | 1 |
| Mariash, CN | 1 |
| Bingham, C | 1 |
| Carr, FE | 1 |
| Oppenheimer, JH | 1 |
| Kaptein, EM | 1 |
| Feinstein, EI | 1 |
| Nicoloff, JT | 1 |
| Massry, SG | 1 |
| Tyzbir, RS | 1 |
| Kunin, AS | 1 |
| Henriquez, C | 1 |
| Seo, H | 1 |
| Martino, E | 1 |
| Hohenegger, M | 1 |
| Kramar, R | 1 |
| Om, P | 1 |
| Weissel, M | 2 |
| Watschinger, R | 1 |
| Giordano, C | 1 |
| De Santo, NG | 1 |
| Carella, C | 2 |
| Mioli, V | 1 |
| Bazzato, G | 1 |
| Di Leo, VA | 1 |
| Amato, G | 2 |
| Tarchini, A | 1 |
| Coli, U | 1 |
| Landini, S | 1 |
| Arreola, F | 1 |
| Paniagua, R | 1 |
| Pérez, A | 1 |
| Díaz-Bensussen, S | 1 |
| Junco, E | 1 |
| Villalpando, S | 1 |
| Exaire, E | 1 |
| Napolitano, G | 1 |
| Bonomini, M | 1 |
| Bomba, G | 1 |
| Bucci, I | 1 |
| Todisco, V | 1 |
| Albertazzi, A | 1 |
| Monaco, F | 1 |
| Savdie, E | 1 |
| Stewart, JH | 1 |
| Mahony, JF | 1 |
| Hayes, JM | 1 |
| Lazarus, L | 1 |
| Simons, LA | 1 |
| Chopra, IJ | 1 |
| Solomon, DH | 1 |
| Hepner, GW | 1 |
| Morgenstein, AA | 1 |
| Fritzsche, H | 1 |
| Stummvoll, HK | 1 |
| Kolbe, H | 1 |
| Wolf, A | 1 |
| Seyfried, H | 1 |
| Ramirez, G | 1 |
| O'Neill, W | 1 |
| Jubiz, W | 1 |
| Bloomer, HA | 1 |
| Bloehr, H | 1 |
| Bregengaard, C | 1 |
| Povlsen, JV | 1 |
| Yeksan, M | 1 |
| Tamer, N | 1 |
| Cirit, M | 1 |
| Türk, S | 1 |
| Akhan, G | 1 |
| Akkus, I | 1 |
| Erkul, I | 1 |
| Muñoz, BE | 1 |
| Barsano, CP | 2 |
| Quintanilla, A | 2 |
| Pullen, GL | 1 |
| Iqbal, Z | 2 |
| Dunn, RB | 1 |
| Tsalikian, E | 1 |
| Flanigan, MJ | 2 |
| Lacour, B | 1 |
| Roullet, JB | 1 |
| Ricordel, Y | 1 |
| Drüeke, T | 1 |
| Zavala, DC | 1 |
| Freeman, RM | 1 |
| Burke, SF | 1 |
| Quintana, M | 1 |
| Munoz, E | 1 |
| Zuccalà, A | 1 |
| Santoro, A | 1 |
| Gaggi, R | 1 |
| Chiarini, C | 1 |
| Degli Esposti, E | 1 |
| Sturani, A | 1 |
| Zucchelli, P | 1 |
| Checchia, G | 1 |
| Querques, M | 1 |
| Ktena, M | 1 |
| Tappi, A | 1 |
| D'Amato, V | 1 |
| Sennesael, JJ | 1 |
| Verbeelen, DL | 1 |
| Jonckheer, MH | 1 |
| DeSanto, NG | 1 |
| Fine, RN | 1 |
| Leumann, E | 1 |
| Fine, S | 1 |
| Capodicasa, G | 1 |
| Nuzzi, F | 1 |
| Capasso, G | 1 |
| De Simone, V | 1 |
1 review available for triiodothyronine and Uremia
| Article | Year |
|---|---|
Thyroid hormone action in chronic kidney disease.
Topics: Humans; Kidney Failure, Chronic; Models, Biological; Signal Transduction; Thyroid Hormones; Triiodot | 2008 |
2 trials available for triiodothyronine and Uremia
| Article | Year |
|---|---|
Thyroid function and plasma selenium in chronic uremic patients on hemodialysis treatment.
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Female; Humans; Immunoradiometric Assay; Ma | 1996 |
Blunted peripheral tissue responsiveness to thyroid hormone in uremic patients.
Topics: Adult; Aged; Female; Humans; Ipodate; Lymphocytes; Male; Middle Aged; Monocytes; Ouabain; Oxygen Con | 1987 |
26 other studies available for triiodothyronine and Uremia
| Article | Year |
|---|---|
Protective effect of low serum thyroid hormone concentration on occurrence of functional delayed kidney allograft function early after transplantation.
Topics: Cross-Sectional Studies; Delayed Graft Function; Female; Humans; Kidney Failure, Chronic; Kidney Tra | 2011 |
Performance evaluation of the Vitros(®)3600 immunodiagnostic system for the determination of free thyroid hormones.
Topics: Humans; Immunoassay; Luminescent Measurements; Reagent Kits, Diagnostic; Thyroxine; Triiodothyronine | 2011 |
Discordant elevation of the common alpha-subunit of the glycoprotein hormones compared to beta-subunits in serum of uremic patients.
Topics: Adult; Aged; Chorionic Gonadotropin; Female; Follicle Stimulating Hormone; Glycoprotein Hormones, al | 1981 |
Uremia decreases nuclear 3,5,3'-triiodothyronine receptors in rats.
Topics: Animals; Blood Urea Nitrogen; Cell Nucleus; Kidney; Liver; Male; Organ Specificity; Rats; Receptors, | 1980 |
Reduced triiodothyronine content in liver but not pituitary of the uremic rat model: demonstration of changes compatible with thyroid hormone deficiency in liver only.
Topics: Animals; Body Weight; Disease Models, Animal; Liver; Male; Nephrectomy; Organ Size; Organ Specificit | 1984 |
Hepatic messenger ribonucleic acid activity profiles in experimental azotemia in the rat. Relationship to food intake and thyroid function.
Topics: Animals; Blood Proteins; Body Weight; DNA; Eating; Liver; Male; Metabolic Clearance Rate; Nephrectom | 1984 |
Alterations of serum reverse triiodothyronine and thyroxine kinetics in chronic renal failure: role of nutritional status, chronic illness, uremia, and hemodialysis.
Topics: Adult; Aged; Body Weight; Chronic Disease; Female; Humans; Infections; Kidney Failure, Chronic; Kine | 1983 |
Effects of dietary manipulation on hepatic mitochondrial metabolism and serum triiodothyronine levels in chronically uremic rats.
Topics: Animals; Chronic Disease; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Glycerolphosp | 1980 |
Thyroid function in a uremic rat model. Evidence suggesting tissue hypothyroidism.
Topics: Animals; Blood Urea Nitrogen; Disease Models, Animal; Glycerolphosphate Dehydrogenase; Humans; Hypot | 1980 |
Influence of triiodothyronine, amphetamine, and dinitrophenol (DNP) on the induced metabolic rate in uremic and acidotic rats.
Topics: Acidosis; Amphetamine; Animals; Dinitrophenols; Male; Oxygen Consumption; Rats; Rats, Inbred Strains | 1982 |
Thyroidal status in uremia - effects of hemodialysis and CAPD.
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Peritoneal Dialysis; Peritoneal Dialysis, Continuous | 1982 |
Effect of zinc treatment on serum thyroid hormones in uremic patients under peritoneal dialysis.
Topics: Adult; Humans; Male; Middle Aged; Peritoneal Dialysis; Thyroid Hormones; Thyrotropin; Thyroxine; Tri | 1993 |
Circulating thyroid hormone levels and adequacy of dialysis.
Topics: Adult; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Thyroxine; Thyrox | 1978 |
Misleadingly low free thyroxine index and usefulness of reverse triiodothyronine measurement in nonthyroidal illnesses.
Topics: Adult; Aged; Diagnosis, Differential; Diagnostic Errors; Evaluation Studies as Topic; Heart Diseases | 1979 |
[Serum concentrations of thyroid hormones in severe non-thyroidal illnesses (author's transl)].
Topics: Humans; Liver Cirrhosis; Myocardial Infarction; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothy | 1978 |
Thyroid dysfunction in uremia: evidence for thyroid and hypophyseal abnormalities.
Topics: Adolescent; Adult; Aged; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pituitary Gland | 1976 |
Triiodothyronine stimulates growth of peripheral blood mononuclear cells in serum-free cultures in uremic patients.
Topics: Cells, Cultured; Culture Media; Dinoprostone; Female; Humans; In Vitro Techniques; Indomethacin; Int | 1992 |
Effect of recombinant human erythropoietin (r-HuEPO) therapy on plasma FT3, FT4, TSH, FSH, LH, free testosterone and prolactin levels in hemodialysis patients.
Topics: Adolescent; Adult; Aged; Erythropoietin; Female; Follicle Stimulating Hormone; Hormones; Humans; Lut | 1992 |
The hepatocellular thyroid status of uremic rats estimated from the abundances of thyroid hormone-dependent nucleoplasmic proteins.
Topics: Animals; Body Weight; Cell Nucleus; Hyperthyroidism; Hypothyroidism; Liver; Male; Nephrectomy; Nucle | 1991 |
Augmentation of protein degradation by L-triiodothyronine in uremia.
Topics: Adult; Chromatography; Energy Intake; Energy Metabolism; Female; Food Analysis; Humans; Leucine; Mal | 1989 |
Chronic triiodothyronine supplementation does not improve the lipoprotein disorders of mildly uremic rats.
Topics: Animals; Body Weight; Cholesterol; Creatinine; Insulin; Lipoproteins; Male; Rats; Rats, Inbred Strai | 1987 |
The effects of postoperative factors on serum thyroid hormones and rat liver nuclear 3,5,3'-triiodothyronine receptor concentrations in surgical models of uremia and regenerating liver.
Topics: Animals; Body Weight; Cell Nucleus; Chronic Disease; Disease Models, Animal; Fasting; Hepatectomy; L | 1987 |
Relationship between plasma noradrenaline and blood pressure in uremia.
Topics: Blood Pressure; Bromocriptine; Hematocrit; Humans; Kidney Failure, Chronic; Longitudinal Studies; Ma | 1985 |
Follow up of the thyroid function in patients (pts) in treatment with C.A.P.D.
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Thyroid | 1985 |
Thyroid dysfunction in patients on regular hemodialysis: evaluation of the stable intrathyroidal iodine pool, incidence of goiter and free thyroid hormone concentration.
Topics: Adult; Aged; Female; Goiter; Humans; Iodine; Male; Middle Aged; Renal Dialysis; Thyroid Gland; Thyro | 1985 |
Thyroid function in uremic children--studies at various stages of nephron loss and during treatment with hemodialysis and/or CAPD.
Topics: Adolescent; Child; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Nephrons; Peritoneal | 1985 |