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triiodothyronine and Tachycardia

triiodothyronine has been researched along with Tachycardia in 39 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

Research Excerpts

ExcerptRelevanceReference
"Old studies in animals and unblinded studies in a few hyperthyroid patients suggested that L -carnitine is a periferal antagonist of thyroid hormone action at least in some tissues."9.09Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. ( Benvenga, S; Campenni, A; Lapa, D; Ruggeri, RM; Russo, A; Trimarchi, F, 2001)
"We examined the chronic electrophysiologic, systemic, and pharmacologic effects of chronic oral amiodarone therapy in 24 patients with refractory ventricular tachycardia and organic heart disease."9.05Chronic effects of amiodarone in patients with refractory ventricular tachycardia. ( Cappello, G; Rothbart, ST; Saksena, S, 1983)
"Although there are two types of amiodarone-induced thyrotoxicosis (AIT), only type II AIT has been seen at our institution in Japan so far."7.73Mild and short recurrence of type II amiodarone-induced thyrotoxicosis in three patients receiving amiodarone continuously for more than 10 years. ( Hagiwara, N; Kasanuki, H; Matsuda, N; Onoda, N; Sato, K; Shiga, T; Takano, K, 2006)
" The pharmacokinetics and the dromotropic action (increased PQ interval) of intravenously administered ajmaline (2 mg kg-1) were studied in hyperthyroid rats with sinus tachycardia."7.67Pharmacokinetics and dromotropic activity of ajmaline in rats with hyperthyroidism. ( Hashimoto, Y; Hori, R; Kamiya, A; Okumura, K; Yasuhara, M, 1989)
"In 23 patients with symptomatic severe supraventricular and ventricular tachyarrhythmias the effectiveness and the side effects of a long-term therapy with the class III antiarrhythmic drug Amiodarone (Cordarone) in a dosage of 100-800 mg/die in monotherapy and combination therapy were investigated."7.67[Long-term therapy with amiodarone in tachyarrhythmias--report on various experiences with special reference to its side effects]. ( Assmann, I, 1985)
"Amiodarone is a potent new antiarrhythmic drug that has multiple effects on thyroid function, including inhibition of extrathyroidal triiodothyronine production and rarely, iodine-induced hypothyroidism."5.27Myxedema coma during long-term amiodarone therapy. ( Cantley, LK; Dalldorf, FG; Foster, JR; Mazonson, PD; Utiger, RD; Williams, ML, 1984)
"Old studies in animals and unblinded studies in a few hyperthyroid patients suggested that L -carnitine is a periferal antagonist of thyroid hormone action at least in some tissues."5.09Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. ( Benvenga, S; Campenni, A; Lapa, D; Ruggeri, RM; Russo, A; Trimarchi, F, 2001)
"We examined the chronic electrophysiologic, systemic, and pharmacologic effects of chronic oral amiodarone therapy in 24 patients with refractory ventricular tachycardia and organic heart disease."5.05Chronic effects of amiodarone in patients with refractory ventricular tachycardia. ( Cappello, G; Rothbart, ST; Saksena, S, 1983)
"Although there are two types of amiodarone-induced thyrotoxicosis (AIT), only type II AIT has been seen at our institution in Japan so far."3.73Mild and short recurrence of type II amiodarone-induced thyrotoxicosis in three patients receiving amiodarone continuously for more than 10 years. ( Hagiwara, N; Kasanuki, H; Matsuda, N; Onoda, N; Sato, K; Shiga, T; Takano, K, 2006)
" The pharmacokinetics and the dromotropic action (increased PQ interval) of intravenously administered ajmaline (2 mg kg-1) were studied in hyperthyroid rats with sinus tachycardia."3.67Pharmacokinetics and dromotropic activity of ajmaline in rats with hyperthyroidism. ( Hashimoto, Y; Hori, R; Kamiya, A; Okumura, K; Yasuhara, M, 1989)
"In 23 patients with symptomatic severe supraventricular and ventricular tachyarrhythmias the effectiveness and the side effects of a long-term therapy with the class III antiarrhythmic drug Amiodarone (Cordarone) in a dosage of 100-800 mg/die in monotherapy and combination therapy were investigated."3.67[Long-term therapy with amiodarone in tachyarrhythmias--report on various experiences with special reference to its side effects]. ( Assmann, I, 1985)
" When 5 x 10(-7) to 5 x 10(-6)m l-triiodothyronine is added to the culture medium arrhythmias and or tachycardia gradually appear, just as in thyrotoxicosis in vivo."3.65Studies of isolated fetal mouse hearts in organ culture. Evidence for a direct effect of triiodothyronine in enhancing cardiac responsiveness to norepinephrine. ( Wildenthal, K, 1972)
"Triiodothyronine (T3) was markedly raised with normal TSH receptor antibodies, and the patient later confessed to supplementary testosterone and T3 use as part of bodybuilding activities."1.56Delayed diagnosis of T3 supplementation in a bodybuilder presenting with tachycardia and features of sepsis. ( Pal, A; Warner, BE; Woodrow, CJ, 2020)
" The beginning of therapy, dosage of drugs, length of application and results of treatment are critically evaluated, with special emphasis on the rate and time of remission, on the frequency of recurrences and on the success of additional treatments such as surgery and/or radioiodine application."1.31[Graves' disease. Clinical features and treatment results]. ( Amor, H; Crivellaro, C; Leimgruber, K; Oberhofer, R, 2001)
"Amiodarone is a potent new antiarrhythmic drug that has multiple effects on thyroid function, including inhibition of extrathyroidal triiodothyronine production and rarely, iodine-induced hypothyroidism."1.27Myxedema coma during long-term amiodarone therapy. ( Cantley, LK; Dalldorf, FG; Foster, JR; Mazonson, PD; Utiger, RD; Williams, ML, 1984)
" There was no significant correlation between serum amiodarone or desethylamiodarone levels and dosage of amiodarone."1.27Amiodarone efficacy in a young population: relationship to serum amiodarone and desethylamiodarone levels. ( Garson, A; Kannan, R; McVey, P; Miller, S; Singh, BN; Yabek, SM, 1987)
"When amiodarone was stopped in nine patients, the changes in QTc, T4 and rT3 regressed toward normal and arrhythmia recurred in eight 2-20 weeks (mean 7."1.26Pharmacokinetic significance of serum reverse T3 levels during amiodarone treatment: a potential method for monitoring chronic drug therapy. ( Hendrickson, JA; Hershman, J; Melmed, S; Nademanee, K; Reed, AW; Singh, BN, 1982)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199026 (66.67)18.7374
1990's2 (5.13)18.2507
2000's6 (15.38)29.6817
2010's3 (7.69)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Çetin, S1
Güven, M1
Bolayır, B1
Şimşek, M1
Soylu, H1
Geneş, D1
Ay, N1
Diri, H1
Warner, BE1
Woodrow, CJ1
Pal, A1
Pai, G1
Jain, V1
Cantrell, L1
Pramyothin, P1
Leung, AM1
Pearce, EN1
Malabanan, AO1
Braverman, LE1
CORDAY, E1
GOLD, H1
JAFFE, HL1
KURLAND, GS1
GOLODETZ, A1
HAMOLSKY, MW1
FREEDBERG, AS1
WINAWER, SJ1
ROSEN, SM1
COHN, H2
PERLMUTTER, M1
DANOWSKI, TS2
SARVER, ME1
D AMBROSIA, RD1
MOSES, C2
LIMAYE, NR1
SUNDER, JH1
COHN, RE1
Bayer, Y1
Fasshauer, M1
Paschke, R1
Sato, K1
Shiga, T1
Matsuda, N1
Onoda, N1
Takano, K1
Hagiwara, N1
Kasanuki, H1
Ogriseg, M1
Fill, H1
Kirchmair, W1
Stühlinger, W1
Saksena, S1
Rothbart, ST1
Cappello, G1
Mazonson, PD1
Williams, ML1
Cantley, LK1
Dalldorf, FG1
Utiger, RD1
Foster, JR1
Krusell, LR1
Husted, SE1
Richelsen, B1
Köbberling, J1
Hintze, G1
Blossey, HC1
Dirks, H1
Emrich, D1
Mayer, G1
Schicha, H1
Nademanee, K1
Singh, BN3
Hendrickson, JA1
Reed, AW1
Melmed, S1
Hershman, J1
Masullo, P1
Venditti, P1
Agnisola, C1
Di Meo, S1
Crivellaro, C1
Oberhofer, R1
Leimgruber, K1
Amor, H1
Benvenga, S2
Ruggeri, RM1
Russo, A1
Lapa, D1
Campenni, A1
Trimarchi, F2
Parikh, S1
Ando, S1
Schneider, A1
Skarulis, MC1
Sarlis, NJ1
Yen, PM1
Venkatesh, N1
Lynch, JJ1
Uprichard, AC1
Kitzen, JM1
Lucchesi, BR1
Jaffiol, C1
Baldet, L1
Torresani, J1
Bismuth, J1
Papachristou, C1
Hashimoto, Y1
Yasuhara, M1
Kamiya, A1
Okumura, K1
Hori, R1
Jonderko, G1
Kocot, E1
Marcisz, C1
Vermiglio, F1
Granata, A1
Sobbrio, G1
Melluso, C1
Carerj, S1
Arrigo, F1
Consolo, F1
Rao, RH1
Buckell, HM1
Rege, VP1
Spathis, GS1
Gorman, RL1
Chamberlain, JM1
Rose, SR1
Oderda, GM1
Kannan, R1
Yabek, SM1
Garson, A1
Miller, S1
McVey, P1
Mechlis, S1
Lubin, E1
Laor, J1
Margaliot, M1
Strasberg, B1
Morady, F1
DiCarlo, LA1
Krol, RB1
Baerman, JM1
de Buitleir, M1
Assmann, I1
Schatz, DL1
Campbell, M1
Fish, B1
David, R1
Shapiro, T1
Collins, P1
Koh, C1
Kallee, E1
Wahl, R1
Secker, KH1
Mallet, D1
Bohner, J1
Wildenthal, K2

Trials

4 trials available for triiodothyronine and Tachycardia

ArticleYear
Can a novel drug dose be used for T3 suppression test?
    Endocrine, 2023, Volume: 82, Issue:3

    Topics: Humans; Prospective Studies; Tachycardia; Thyroid Hormone Resistance Syndrome; Thyrotropin; Thyroxin

2023
Chronic effects of amiodarone in patients with refractory ventricular tachycardia.
    International journal of cardiology, 1983, Volume: 3, Issue:3

    Topics: Administration, Oral; Adult; Aged; Amiodarone; Atrioventricular Node; Benzofurans; Clinical Trials a

1983
Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:8

    Topics: Administration, Oral; Adult; Asthenia; Biomarkers; Body Weight; Bone Density; Carnitine; Double-Blin

2001
Liothyronine treatment in psychotic and nonpsychotic children under 6 years.
    Archives of general psychiatry, 1973, Volume: 29, Issue:5

    Topics: Age Factors; Brain Damage, Chronic; Child; Child Behavior Disorders; Child, Preschool; Clinical Tria

1973

Other Studies

35 other studies available for triiodothyronine and Tachycardia

ArticleYear
Delayed diagnosis of T3 supplementation in a bodybuilder presenting with tachycardia and features of sepsis.
    BMJ case reports, 2020, Jan-13, Volume: 13, Issue:1

    Topics: Adult; Athletes; Delayed Diagnosis; Diagnosis, Differential; Humans; Male; Sepsis; Tachycardia; Test

2020
Massive levothyroxine ingestion.
    Indian pediatrics, 2014, Volume: 51, Issue:10

    Topics: Child, Preschool; Female; Gastric Lavage; Humans; Infant; Tachycardia; Thyrotropin; Thyroxine; Triio

2014
Redotex® revisited: intentional overdose with an illegal weight loss product.
    The Journal of emergency medicine, 2012, Volume: 43, Issue:2

    Topics: Adolescent; Anti-Obesity Agents; Atropine; Charcoal; Diazepam; Drug Combinations; Drug Overdose; Emo

2012
Clinical problem-solving. A hidden solution.
    The New England journal of medicine, 2011, Dec-01, Volume: 365, Issue:22

    Topics: Anti-Infective Agents, Local; Diagnosis, Differential; Female; Humans; Iodine Radioisotopes; Middle

2011
Radioiodine treatment of paroxysmal supraventricular tachycardia in the euthroid patient.
    Circulation, 1958, Volume: 17, Issue:5

    Topics: Drug Combinations; Humans; Iodine; Iodine Radioisotopes; Tachycardia; Tachycardia, Paroxysmal; Tachy

1958
Thyroid function in supraventricular tachycardias: turnover of intravenously infused I 131-labeled thyroxine and the red blood cell uptake of I 131-labeled 1-triiodothyronine.
    The Journal of clinical endocrinology and metabolism, 1959, Volume: 19, Issue:1

    Topics: Erythrocytes; Humans; Iodine; Tachycardia; Tachycardia, Supraventricular; Thyroid Function Tests; Th

1959
Myxedema coma with ventricular tachycardia.
    Archives of internal medicine, 1963, Volume: 111

    Topics: Coma; Humans; Myxedema; Tachycardia; Tachycardia, Ventricular; Triiodothyronine

1963
MYXEDEMA CRISIS OF PITUITARY OR THYROID ORIGIN.
    The American journal of medicine, 1964, Volume: 36

    Topics: Chlorides; Cholesterol; Coma; Geriatrics; Humans; Hydrocortisone; Hypopituitarism; Hypothyroidism; M

1964
HYDROCORTISONE AND/OR DESICCATED THYROID IN PHYSIOLOGIC DOSAGE. X. EFFECTS OF THYROID HORMONE EXCESSES ON CLINICAL STATUS AND THYROID INDICES.
    Metabolism: clinical and experimental, 1964, Volume: 13

    Topics: Electrocardiography; Humans; Hydrocortisone; Hyperthyroidism; Muscular Diseases; Reflex; Reflex, Str

1964
HYDROCORTISONE AND/OR DESICCATED THYROID IN PHYSIOLOGIC DOSAGE. XVII. MAJOR AND MINOR THYROIDAL INDICES DURING THERAPY WITH LARGE DOSAGES OF DESICCATED THYROID.
    Metabolism: clinical and experimental, 1965, Volume: 14

    Topics: Achilles Tendon; Blood Pressure; Body Weight; Cholesterol; Drug Therapy; Electrocardiography; Glycer

1965
The novel missense mutation methionine 442 threonine in the thyroid hormone receptor beta causes thyroid hormone resistance: a case report.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2004, Volume: 112, Issue:2

    Topics: Atrial Fibrillation; Goiter, Nodular; Humans; Male; Methionine; Middle Aged; Mutation, Missense; Ped

2004
Mild and short recurrence of type II amiodarone-induced thyrotoxicosis in three patients receiving amiodarone continuously for more than 10 years.
    Endocrine journal, 2006, Volume: 53, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Autoantibodies; Humans; Immunoglobulins, Thyroid-Stimulati

2006
[Plasma filtration treatment in thyreotoxic crisis].
    Schweizerische medizinische Wochenschrift, 1981, Apr-25, Volume: 111, Issue:17

    Topics: Aged; Blood; Humans; Hyperthyroidism; Male; Receptors, Cell Surface; Tachycardia; Thyroid Crisis; Th

1981
Myxedema coma during long-term amiodarone therapy.
    The American journal of medicine, 1984, Volume: 77, Issue:4

    Topics: Aged; Amiodarone; Benzofurans; Coma; Humans; Male; Myxedema; Tachycardia; Thyroid Gland; Thyrotropin

1984
[Severe poisoning with thyroid hormones in a body builder].
    Ugeskrift for laeger, 1983, Aug-08, Volume: 145, Issue:32

    Topics: Adolescent; Female; Humans; Physical Exertion; Respiration Disorders; Tachycardia; Thyroxine; Triiod

1983
[Diagnostic problems of hyperthyroidism in the older age group (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, Jul-31, Volume: 106, Issue:31-32

    Topics: Age Factors; Aged; Body Weight; Depression; Dyspnea; Female; Humans; Hyperthyroidism; Male; Middle A

1981
Pharmacokinetic significance of serum reverse T3 levels during amiodarone treatment: a potential method for monitoring chronic drug therapy.
    Circulation, 1982, Volume: 66, Issue:1

    Topics: Adult; Aged; Amiodarone; Atrial Flutter; Benzofurans; Electrocardiography; Heart Ventricles; Humans;

1982
Role of nitric oxide in the reperfusion induced injury in hyperthyroid rat hearts.
    Free radical research, 2000, Volume: 32, Issue:5

    Topics: Animals; Antioxidants; Enzyme Inhibitors; Hyperthyroidism; Injections, Intraperitoneal; Lipid Peroxi

2000
[Graves' disease. Clinical features and treatment results].
    Acta medica Austriaca, 2001, Volume: 28, Issue:2

    Topics: Antithyroid Agents; Disease-Free Survival; Female; Graves Disease; Humans; Iodine Radioisotopes; Mal

2001
Resistance to thyroid hormone in a patient without thyroid hormone receptor mutations.
    Thyroid : official journal of the American Thyroid Association, 2002, Volume: 12, Issue:1

    Topics: Adult; DNA-Binding Proteins; Fatigue; Female; Goiter; Humans; Intelligence Tests; Mutation; National

2002
Hypothyroidism renders protection against lethal ventricular arrhythmias in a conscious canine model of sudden death.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dogs; Electroencephalography; Electrophysiolo

1991
A case of hypersensitivity to thyroid hormones with normally functioning thyroid gland and increased nuclear triiodothyronine receptors.
    Journal of endocrinological investigation, 1990, Volume: 13, Issue:10

    Topics: Carbimazole; Cell Nucleus; Humans; Lymphocytes; Male; Middle Aged; Receptors, Thyroid Hormone; Tachy

1990
Pharmacokinetics and dromotropic activity of ajmaline in rats with hyperthyroidism.
    British journal of pharmacology, 1989, Volume: 96, Issue:1

    Topics: Ajmaline; Animals; Heart; Hyperthyroidism; In Vitro Techniques; Male; Protein Binding; Rats; Rats, I

1989
[Studies of stimulating and conducting activities of the heart in hyperthyroidism].
    Polskie Archiwum Medycyny Wewnetrznej, 1988, Volume: 79, Issue:2

    Topics: Adult; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Conduction System; Heart Rate;

1988
Abnormalities in pituitary thyroid axis function tests in patients with paroxysmal supraventricular arrhythmias.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1987, Volume: 19, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibodies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pr

1987
Thyrotropin hyperresponsiveness to TRH despite hyperthyroxinemia in amiodarone-treated subjects.
    Metabolism: clinical and experimental, 1987, Volume: 36, Issue:11

    Topics: Amiodarone; Female; Humans; Male; Tachycardia; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine

1987
Massive levothyroxine overdose: high anxiety--low toxicity.
    Pediatrics, 1988, Volume: 82, Issue:4

    Topics: Humans; Infant; Male; Propranolol; Tachycardia; Thyroxine; Triiodothyronine

1988
Amiodarone efficacy in a young population: relationship to serum amiodarone and desethylamiodarone levels.
    American heart journal, 1987, Volume: 114, Issue:2

    Topics: Adolescent; Adult; Amiodarone; Child; Child, Preschool; Heart Ventricles; Humans; Infant; Tachycardi

1987
Amiodarone-induced thyroid gland dysfunction.
    The American journal of cardiology, 1987, Apr-01, Volume: 59, Issue:8

    Topics: Amiodarone; Female; Humans; Hypothyroidism; Iodine; Male; Tachycardia; Thyroid Diseases; Thyroid Gla

1987
Acute and chronic effects of amiodarone on ventricular refractoriness, intraventricular conduction and ventricular tachycardia induction.
    Journal of the American College of Cardiology, 1986, Volume: 7, Issue:1

    Topics: Administration, Oral; Aged; Amiodarone; Benzofurans; Cardiac Pacing, Artificial; Electric Stimulatio

1986
[Long-term therapy with amiodarone in tachyarrhythmias--report on various experiences with special reference to its side effects].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1985, Jun-01, Volume: 40, Issue:11

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Benzofurans; Bradycardia; Drug Therapy, Combination; Elec

1985
Serum free thyroxine and thyroxine-binding protein studies in patients with supraventricular tachycardias.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Aged; Dialysis; Female; Humans; Iodine Isotopes; Male; Middle Aged; Tachycardia;

1967
[Thyrotoxic crisis: symptoms and therapy (author's transl)].
    Medizinische Klinik, 1973, Dec-21, Volume: 68, Issue:51

    Topics: Adult; Aged; Ascorbic Acid; Body Temperature; Contrast Media; Female; First Aid; Germany, West; Huma

1973
Studies of isolated fetal mouse hearts in organ culture. Evidence for a direct effect of triiodothyronine in enhancing cardiac responsiveness to norepinephrine.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:10

    Topics: Animals; Arrhythmias, Cardiac; Drug Interactions; Drug Synergism; Fetus; Heart Atria; Heart Rate; Mi

1972
Responses to cardioactive drugs of fetal mouse hearts maintained in organ culture.
    The American journal of physiology, 1971, Volume: 221, Issue:1

    Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Bradycardia; Culture Techniques; Digitalis Glycosides;

1971