Page last updated: 2024-11-08

triiodothyronine and Stunted Growth

triiodothyronine has been researched along with Stunted Growth in 43 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
" Administration of up to 900 mug of thyroxine or 225 mug of triiodothyronine led to minimal changes in urinary hydroxyproline excretion, pulse rate and body weight."3.65Peripheral resistance to thyroxine: a cause of short stature in a boy without goitre. ( Bardin, CW; Keiser, HR; Schneider, G, 1975)
"The hypothyroidism is a frequent endocrinopathos."1.31[Hypothyroidism in children. 82 cases]. ( Ben Amar, H; Ben Slimen, M; Hachicha, M; Kolsi, S; Loulou, F; Mahfoudh, A; Rekik, S; Triki, A, 2002)
"The effects of GH therapy on thyroid function among previous reports have shown remarkable discrepancies, probably due to differences in hormone assay methods, degree of purification of former pituitary-derived GH preparations, dosage schedules, diagnostic criteria, patient selection, duration of treatment and study design."1.31Changes in serum thyroid hormones levels and their mechanisms during long-term growth hormone (GH) replacement therapy in GH deficient children. ( Abucham, J; MacCagnan, P; Oliveira, JH; Portes, ES, 2000)
"A series of 14 children with Crohn's disease and growth retardation was screened for endocrine dysfunction."1.27Endocrine dysfunction in children with Crohn's disease. ( Chong, SK; Grossman, A; Rees, LH; Walker-Smith, JA, 1984)
"Nine patients with Turner's syndrome aged 7 to 13 years were treated with recombinant human growth hormone (hGH) at a dose of 0."1.27Factors attenuating growth promoting effect of growth hormone therapy for Turner's syndrome. ( Kajiwara, S; Miyagawa, K; Miyamori, C; Sato, T; Shimizu, M, 1988)
" After long-term administration of nitrate a significant decrease of serum somatomedin activity was found which also showed a positive correlation with a decrease of body weight gain."1.27Growth impairment caused by dietary nitrate intake regulated via hypothyroidism and decreased somatomedin. ( Hesse, V; Jahreis, G; Lüdke, H; Schöne, F, 1987)
"Failure to recognize and treat hypothyroidism in these pubertal patients may compromise the adult height, since skeletal maturation will proceed under the influence of sex hormones despite the presence of hypothyroidism."1.26Clinical recognition of juvenile hypothyroidism in the early stage. ( Abbassi, V; Cancellieri, RP; Rigterink, E, 1980)
"Compensated hypothyroidism is frequent in cystinosis and may be one factor in the severe growth retardation in this condition."1.26[Thyroid involvement in cystinosis]. ( Broyer, M; Czernichow, P; Lenoir, G; Rappaport, R; Roy, MP, 1978)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199017 (39.53)18.7374
1990's9 (20.93)18.2507
2000's10 (23.26)29.6817
2010's6 (13.95)24.3611
2020's1 (2.33)2.80

Authors

AuthorsStudies
Adamczewska, K1
Adamczewski, Z1
Łupińska, A1
Lewiński, A1
Stawerska, R1
Florêncio, TM1
Bueno, NB1
Britto, RA1
Albuquerque, FC1
Lins, IL1
Sawaya, AL1
Salerno, M1
Capalbo, D1
Cerbone, M1
De Luca, F1
Taguchi, Y1
Tasaki, Y1
Terakado, K1
Kobayashi, K1
Machida, T1
Kobayashi, T1
Bochukova, E1
Schoenmakers, N1
Agostini, M1
Schoenmakers, E1
Rajanayagam, O1
Keogh, JM1
Henning, E1
Reinemund, J1
Gevers, E1
Sarri, M1
Downes, K1
Offiah, A1
Albanese, A1
Halsall, D1
Schwabe, JW1
Bain, M1
Lindley, K1
Muntoni, F1
Vargha-Khadem, F1
Khadem, FV1
Dattani, M1
Farooqi, IS1
Gurnell, M1
Chatterjee, K1
Hamajima, T1
Mushimoto, Y1
Kobayashi, H1
Saito, Y1
Onigata, K2
Monk, JA1
Sims, NA1
Dziegielewska, KM1
Weiss, RE2
Ramsay, RG1
Richardson, SJ1
Liu, JH1
Yi, ZW1
Friedrichsen, S1
Christ, S1
Heuer, H1
Schäfer, MK1
Mansouri, A1
Bauer, K1
Visser, TJ2
Hachicha, M1
Mahfoudh, A1
Loulou, F1
Ben Amar, H1
Kolsi, S1
Ben Slimen, M1
Rekik, S1
Triki, A1
Suzuki, H1
Cheng, SY1
Williams, FL1
Mires, GJ1
Barnett, C1
Ogston, SA1
van Toor, H1
Hume, R1
Chong, SK1
Grossman, A1
Walker-Smith, JA1
Rees, LH1
Labbe, A1
Dubray, C1
Gaillard, G1
Besse, G1
Assali, P1
Malpuech, G1
Rochiccioli, P1
Dutau, G1
Enjaume, P1
Dupont, M1
Abbassi, V1
Rigterink, E1
Cancellieri, RP1
Hotz, J1
Goebell, H1
Hartmann, I1
Förster, S1
Hackenberg, K1
Tharandt, L1
Marin, G1
Malozowski, SN1
Barnes, K1
Southers, J1
Cristiano, A2
Cassorla, F1
Hayashi, Y1
Janssen, OE1
Murata, Y1
Seo, H1
Refetoff, S1
Burman, P1
Hetta, J1
Wide, L1
Månsson, JE1
Ekman, R1
Karlsson, FA1
Evliyaoğlu, N1
Kilinç, Y1
Sargin, O1
Takamatsu, J1
Ito, M1
Yamano, Y1
Fukao, T1
Sakane, S1
Ohsawa, N1
de Boer, JA1
Schoemaker, J1
van der Veen, EA1
Krekmanova, L1
Carlstedt-Duke, J1
Brönnegård, M1
Marcus, C1
Gröndahl, E1
Modéer, T1
Dahllöf, G1
Portes, ES1
Oliveira, JH1
MacCagnan, P1
Abucham, J1
Hornick, JL1
Van Eenaeme, C1
Gérard, O1
Dufrasne, I1
Istasse, L1
Hasan, W1
Cowen, T1
Barnett, PS1
Elliot, E1
Coskeran, P1
Bouloux, PM1
Miyamoto, J1
Hasegawa, Y1
Ohnami, N1
Kinoshita, E1
Nishi, Y1
Tachibana, K1
Hasegawa, T1
Arii, J1
Tanabe, Y1
Makino, M1
Sato, H1
Kohno, Y1
Schneider, G1
Keiser, HR1
Bardin, CW1
Madeddu, G1
Dore, A1
Marongiu, A1
Langer-Costanzi, M1
Czernichow, P1
Lenoir, G1
Roy, MP1
Rappaport, R1
Broyer, M1
Municchi, G1
Malozowski, S1
Nisula, BC1
Rose, SR1
Hammond, AC1
Elsasser, TH1
Olson, TA1
Alain, N1
Zipf, WB1
Sato, T1
Miyamori, C1
Kajiwara, S1
Miyagawa, K1
Shimizu, M1
Jahreis, G1
Schöne, F1
Lüdke, H1
Hesse, V1
Bessho, F1
Bellinger, LL1
Bernardis, LL1
McCusker, RH1
Campion, DR1
Lehr, HJ1
Werner, H1
Rudorff, KH1
Herrmann, J1
Root, AW1
Snyder, PJ1
Rezvani, I1
DiGeorge, AM1
Utiger, RD1
Delange, F1
Ermans, AM1
Stanbury, JB1
Kobielowa, Z1
Szybiński, Z1
Gumiński, T1
Tarnawski, A1

Reviews

2 reviews available for triiodothyronine and Stunted Growth

ArticleYear
Subclinical hypothyroidism in childhood - current knowledge and open issues.
    Nature reviews. Endocrinology, 2016, Volume: 12, Issue:12

    Topics: Anticonvulsants; Antiviral Agents; Asymptomatic Diseases; Atherosclerosis; Bone Diseases, Metabolic;

2016
Mechanisms of reduced and compensatory growth.
    Domestic animal endocrinology, 2000, Volume: 19, Issue:2

    Topics: Animals; Body Composition; Cattle; Eating; Female; Growth Disorders; Growth Hormone; Insulin; Insuli

2000

Trials

2 trials available for triiodothyronine and Stunted Growth

ArticleYear
Growth hormone treatment affects brain neurotransmitters and thyroxine [see comment].
    Clinical endocrinology, 1996, Volume: 44, Issue:3

    Topics: Adult; Aspartic Acid; Cross-Over Studies; Double-Blind Method; Female; Growth Disorders; Growth Horm

1996
The sweating apparatus in growth hormone deficiency, following treatment with r-hGH and in acromegaly.
    Autonomic neuroscience : basic & clinical, 2001, Jun-20, Volume: 89, Issue:1-2

    Topics: Acetylcholinesterase; Acromegaly; Adult; Antigens, Differentiation; Biopsy; Female; Growth Disorders

2001

Other Studies

39 other studies available for triiodothyronine and Stunted Growth

ArticleYear
Strong Positive Correlation between TSH and Ghrelin in Euthyroid Non-Growth Hormone-Deficient Children with Short Stature.
    Molecules (Basel, Switzerland), 2020, Aug-27, Volume: 25, Issue:17

    Topics: Body Height; Child; Child, Preschool; Female; Ghrelin; Growth Disorders; Human Growth Hormone; Human

2020
Waist-to-Height Gain and Triiodothyronine Concentrations in a Cohort of Socially Vulnerable Short-Stature Women: A Four-Year Follow-Up Study.
    Annals of nutrition & metabolism, 2016, Volume: 68, Issue:4

    Topics: Adult; Body Mass Index; Brazil; Cohort Studies; Comorbidity; Female; Growth Disorders; Humans; Hypot

2016
Impaired insulin secretion from the pancreatic islets of hypothyroidal growth-retarded mice.
    The Journal of endocrinology, 2010, Volume: 206, Issue:2

    Topics: Animals; Bodily Secretions; Glucose; Glucose Tolerance Test; Glucose Transporter Type 2; Growth Diso

2010
A mutation in the thyroid hormone receptor alpha gene.
    The New England journal of medicine, 2012, Jan-19, Volume: 366, Issue:3

    Topics: Child; Codon, Nonsense; Female; Growth Disorders; Heterozygote; Humans; Hypothyroidism; Models, Mole

2012
Novel compound heterozygous mutations in the SBP2 gene: characteristic clinical manifestations and the implications of GH and triiodothyronine in longitudinal bone growth and maturation.
    European journal of endocrinology, 2012, Volume: 166, Issue:4

    Topics: Age Determination by Skeleton; Bone Development; Calcification, Physiologic; Child, Preschool; Growt

2012
Delayed development of specific thyroid hormone-regulated events in transthyretin null mice.
    American journal of physiology. Endocrinology and metabolism, 2013, Jan-01, Volume: 304, Issue:1

    Topics: Animals; Blood Chemical Analysis; Blood Glucose; Growth and Development; Growth Disorders; Mice; Mic

2013
[Relationship between serum thyroid hormone and GH-IGF axis, growth failure in nephrotic rats].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2001, Jun-28, Volume: 26, Issue:3

    Topics: Animals; Doxorubicin; Growth Disorders; Male; Nephrotic Syndrome; Random Allocation; Rats; Rats, Spr

2001
Regulation of iodothyronine deiodinases in the Pax8-/- mouse model of congenital hypothyroidism.
    Endocrinology, 2003, Volume: 144, Issue:3

    Topics: Aging; Animals; Brain; Congenital Hypothyroidism; Disease Models, Animal; DNA-Binding Proteins; Fema

2003
[Hypothyroidism in children. 82 cases].
    La Tunisie medicale, 2002, Volume: 80, Issue:11

    Topics: Child; Developmental Disabilities; Female; Growth Disorders; Humans; Hypothyroidism; Infant, Newborn

2002
Compensatory role of thyroid hormone receptor (TR) alpha 1 in resistance to thyroid hormone: study in mice with a targeted mutation in the TR beta gene and deficient in TR alpha 1.
    Molecular endocrinology (Baltimore, Md.), 2003, Volume: 17, Issue:8

    Topics: Animals; Animals, Newborn; Gene Expression Regulation; Genes, erbA; Growth Disorders; Mice; Mice, Mu

2003
Transient hypothyroxinemia in preterm infants: the role of cord sera thyroid hormone levels adjusted for prenatal and intrapartum factors.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:8

    Topics: Chemistry, Clinical; Cohort Studies; Fetal Blood; Gestational Age; Growth Disorders; Humans; Hypothy

2005
Endocrine dysfunction in children with Crohn's disease.
    Journal of pediatric gastroenterology and nutrition, 1984, Volume: 3, Issue:4

    Topics: Adolescent; Blood Sedimentation; Crohn Disease; Endocrine Glands; Female; Folic Acid; Gonadotropin-R

1984
Familial growth retardation with isolated thyroid-stimulating hormone deficiency.
    Clinical pediatrics, 1984, Volume: 23, Issue:12

    Topics: Adolescent; Child; Growth Disorders; Humans; Male; Thyrotropin; Thyrotropin-Releasing Hormone; Thyro

1984
[Combined anterior pituitary stimulation test: insulin + TRH + LH-RH. Results in 76 children (author's transl)].
    Annales de pediatrie, 1980, Volume: 27, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Ho

1980
Clinical recognition of juvenile hypothyroidism in the early stage.
    Clinical pediatrics, 1980, Volume: 19, Issue:12

    Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Female; Goiter; Growth Disorders; Humans; Hypo

1980
[Endocrinologic findings in Crohn's disease].
    Schweizerische medizinische Wochenschrift, 1981, Feb-14, Volume: 111, Issue:7

    Topics: Adolescent; Adult; Body Weight; Chorionic Gonadotropin; Crohn Disease; Female; Growth Disorders; Hum

1981
Endocrine profile of catch-up growth in the cynomolgus monkey.
    Acta endocrinologica, 1993, Volume: 129, Issue:4

    Topics: Animals; Dexamethasone; Endocrine Glands; Growth Disorders; Growth Hormone; Insulin; Insulin-Like Gr

1993
The relative expression of mutant and normal thyroid hormone receptor genes in patients with generalized resistance to thyroid hormone determined by estimation of their specific messenger ribonucleic acid products.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:1

    Topics: Alleles; Base Sequence; Drug Resistance; Exons; Female; Gene Expression; Growth Disorders; Humans; I

1993
Thyroid functions in mild and severe forms of sickle cell anemia.
    Acta paediatrica Japonica : Overseas edition, 1996, Volume: 38, Issue:5

    Topics: Adolescent; Age Determination by Skeleton; Anemia, Sickle Cell; Body Height; Body Weight; Case-Contr

1996
Defective response of body height to growth hormone treatment in resistance to thyroid hormone with short stature.
    Endocrine journal, 1996, Volume: 43 Suppl

    Topics: Adolescent; Body Height; Drug Resistance; Female; Growth Disorders; Human Growth Hormone; Humans; In

1996
Impaired reproductive function in women treated for growth hormone deficiency during childhood.
    Clinical endocrinology, 1997, Volume: 46, Issue:6

    Topics: Adult; Child; Female; Fertilization in Vitro; Follow-Up Studies; Growth Disorders; Growth Hormone; H

1997
Dental maturity in children of short stature, with or without growth hormone deficiency.
    European journal of oral sciences, 1997, Volume: 105, Issue:6

    Topics: Age Determination by Skeleton; Age Determination by Teeth; Aging; Alkaline Phosphatase; Body Height;

1997
Changes in serum thyroid hormones levels and their mechanisms during long-term growth hormone (GH) replacement therapy in GH deficient children.
    Clinical endocrinology, 2000, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Child; Female; Follow-Up Studies; Growth Disorders; Growth Hormone; Hormone Repla

2000
Development of growth hormone and adrenocorticotropic hormone deficiencies in patients with prenatal or perinatal-onset hypothalamic hypopituitarism having invisible or thin pituitary stalk on magnetic resonance imaging.
    Endocrine journal, 2001, Volume: 48, Issue:3

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aging; Body Height; Child; Child, Preschool; Cross-S

2001
Children with irreversible brain damage associated with hypothyroidism and multiple intracranial calcifications.
    Journal of child neurology, 2002, Volume: 17, Issue:4

    Topics: Basal Ganglia Diseases; Calcinosis; Cerebral Palsy; Child, Preschool; Female; Growth Disorders; Huma

2002
Peripheral resistance to thyroxine: a cause of short stature in a boy without goitre.
    Clinical endocrinology, 1975, Volume: 4, Issue:2

    Topics: Adolescent; Age Determination by Skeleton; Body Weight; Child; Drug Resistance; Growth Disorders; Hu

1975
Growth retardation, skeletal maturation and thyroid function in children with homozygous beta-thalassaemia.
    Clinical endocrinology, 1978, Volume: 8, Issue:5

    Topics: Adolescent; Age Determination by Skeleton; Body Height; Child; Child, Preschool; Female; Growth Diso

1978
[Thyroid involvement in cystinosis].
    Archives francaises de pediatrie, 1978, Volume: 35, Issue:9

    Topics: Adolescent; Child; Child, Preschool; Cholesterol; Cystinosis; Female; Follow-Up Studies; Growth Diso

1978
Nocturnal thyrotropin surge in growth hormone-deficient children.
    The Journal of pediatrics, 1992, Volume: 121, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Female; Growth Disorders; Growth Hormone; Humans; Hypoth

1992
Endocrine characteristics of a miniature condition in Brahman cattle: circulating concentrations of some growth-related hormones.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1991, Volume: 197, Issue:4

    Topics: Animals; Cattle; Cattle Diseases; Female; Growth Disorders; Growth Hormone; Insulin; Insulin-Like Gr

1991
Short stature and thyroxine-binding globulin excess: improvement with triiodothyronine treatment.
    Pediatrics, 1988, Volume: 81, Issue:5

    Topics: Body Height; Child, Preschool; Genes, Recessive; Growth Disorders; Humans; Male; Thyrotropin; Thyrot

1988
Factors attenuating growth promoting effect of growth hormone therapy for Turner's syndrome.
    Endocrinologia japonica, 1988, Volume: 35, Issue:5

    Topics: Adolescent; Child; Female; Follicle Stimulating Hormone; Glucose Tolerance Test; Glycated Hemoglobin

1988
Growth impairment caused by dietary nitrate intake regulated via hypothyroidism and decreased somatomedin.
    Endocrinologia experimentalis, 1987, Volume: 21, Issue:3

    Topics: Animals; Feeding Behavior; Growth Disorders; Hypothyroidism; Iodine; Nitrates; Somatomedins; Swine;

1987
[Organ dysfunctions caused by cancer therapy in children].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:9 Suppl

    Topics: Antineoplastic Agents; Bone Development; Child; Child, Preschool; Cyclophosphamide; Female; Growth D

1985
Plasma hormone levels in growth-retarded rats with dorsomedial hypothalamic lesions.
    Physiology & behavior, 1985, Volume: 34, Issue:5

    Topics: Animals; Dorsomedial Hypothalamic Nucleus; Growth Disorders; Growth Hormone; Hypothalamic Diseases;

1985
[T3-thyrotoxicosis in a 3-year-old girl (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Jun-28, Volume: 99, Issue:26

    Topics: Age Determination by Skeleton; Bone Development; Child, Preschool; Diarrhea; Exophthalmos; Female; G

1974
Inhibition of thyrotropin releasing hormone-mediated secretion of thyrotropin by human growth hormone.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:1

    Topics: Adolescent; Adult; Child; Female; Growth Disorders; Growth Hormone; Humans; Hypopituitarism; Male; R

1973
Endemic cretinism in Idjwi Island (Kivu Lake, Zaire Republic).
    Advances in experimental medicine and biology, 1972, Volume: 30

    Topics: Adolescent; Adult; Child; Congenital Hypothyroidism; Democratic Republic of the Congo; Electrocardio

1972
[ 132 -I uptake, the Thiopac test and percentage of free thyroxine in children with arrested somatic development].
    Przeglad lekarski, 1971, Jun-28, Volume: 27, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Dwarfism; Female; Growth; Growth Disorders; Humans; Hypothyroid

1971