triiodothyronine has been researched along with Spinal Cord Injuries in 11 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Following complete spinal cord transection, serotonergic axons crossed the lesion site and tadpole swimming ability was restored when metamorphosis was inhibited, but these events failed to occur when metamorphosis was prematurely induced." | 1.37 | Metamorphosis and the regenerative capacity of spinal cord axons in Xenopus laevis. ( Chittur, SV; Gibbs, KM; Szaro, BG, 2011) |
| "Physiologically complete cervical spinal cord transection results in motor and sensory quadriplegia and interruption of the sympathetic neural pathways; this condition leads to metabolic deficiencies suggestive of abnormal endocrine function." | 1.26 | Steady state hormonal secretion in traumatic quadriplegia. ( Campos, RJ; Carter, RE; Claus-Walker, J; Scurry, M, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Bighinati, A | 1 |
| Focarete, ML | 1 |
| Gualandi, C | 1 |
| Pannella, M | 1 |
| Giuliani, A | 1 |
| Beggiato, S | 1 |
| Ferraro, L | 1 |
| Lorenzini, L | 1 |
| Giardino, L | 1 |
| Calzà, L | 1 |
| Shultz, RB | 1 |
| Wang, Z | 1 |
| Nong, J | 1 |
| Zhang, Z | 1 |
| Zhong, Y | 1 |
| Gibbs, KM | 1 |
| Chittur, SV | 1 |
| Szaro, BG | 1 |
| Prakash, V | 2 |
| Wells, MR | 1 |
| Lofton, SA | 1 |
| Bernstein, JJ | 1 |
| Lin, MS | 1 |
| Song, CH | 1 |
| Perkash, I | 1 |
| Tator, CH | 1 |
| van der Jagt, RH | 1 |
| Huang, TS | 1 |
| Wang, YH | 1 |
| Chiang, HS | 1 |
| Lien, YN | 1 |
| Cheville, AL | 1 |
| Kirshblum, SC | 1 |
| Claus-Walker, J | 1 |
| Scurry, M | 1 |
| Carter, RE | 1 |
| Campos, RJ | 1 |
| Berezin, M | 1 |
| Ohry, A | 1 |
| Shemesh, Y | 1 |
| Zeilig, G | 1 |
| Brooks, ME | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Provocative Testing Using LHRH and hCG of the Pituitary-Gonadal Axis in Persons With Spinal Cord Injury[NCT00223860] | 100 participants (Anticipated) | Interventional | 2001-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 other studies available for triiodothyronine and Spinal Cord Injuries
| Article | Year |
|---|---|
Improved Functional Recovery in Rat Spinal Cord Injury Induced by a Drug Combination Administered with an Implantable Polymeric Delivery System.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Drug Delivery Systems; Female; | 2020 |
Local delivery of thyroid hormone enhances oligodendrogenesis and myelination after spinal cord injury.
Topics: Animals; Cell Differentiation; Drug Implants; Female; Hydrogels; Injections, Spinal; Nerve Fibers, M | 2017 |
Metamorphosis and the regenerative capacity of spinal cord axons in Xenopus laevis.
Topics: Animals; Antithyroid Agents; Axons; Behavior, Animal; Cell Movement; Gene Expression Profiling; Meta | 2011 |
Low serum 3,3',5-triiodothyronine (T3) and reciprocally high serum 3,3',5'-triiodothyronine (reverse T3) concentration in spinal cord injury patients.
Topics: Adolescent; Adult; Aged; Humans; Male; Middle Aged; Paraplegia; Quadriplegia; Spinal Cord Injuries; | 1983 |
Influence of triiodothyronine on the amino acid uptake of brain and spinal cord in normal and spinal hemisected adult rats.
Topics: Amino Acids; Animals; Brain; Lysine; Male; Rats; Rats, Inbred Strains; Spinal Cord; Spinal Cord Inju | 1981 |
Thyroid hypofunction in spinal cord injury patients.
Topics: Adolescent; Adult; Aged; Female; Humans; Hypothyroidism; Male; Middle Aged; Paralysis; Paraplegia; Q | 1980 |
The effect of exogenous thyroid hormones on functional recovery of the rat after acute spinal cord compression injury.
Topics: Acute Disease; Animals; Female; Nerve Regeneration; Rats; Spinal Cord Compression; Spinal Cord Injur | 1980 |
Pituitary-testicular and pituitary-thyroid axes in spinal cord-injured males.
Topics: Adolescent; Adult; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Luteinizing | 1993 |
Thyroid hormone changes in chronic spinal cord injury.
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Energy Metabolism; Euthyroid Sick Syndro | 1995 |
Steady state hormonal secretion in traumatic quadriplegia.
Topics: Calcitonin; Growth Hormone; Hormones; Humans; Male; Parathyroid Hormone; Quadriplegia; Spinal Cord I | 1977 |
Hyperprolactinemia, galactorrhea and amenorrhea in women with a spinal cord injury.
Topics: Adult; Amenorrhea; Female; Follicle Stimulating Hormone; Galactorrhea; Growth Hormone; Humans; Hydro | 1989 |