Page last updated: 2024-11-08

triiodothyronine and Sleep Wake Disorders

triiodothyronine has been researched along with Sleep Wake Disorders in 6 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.

Research Excerpts

ExcerptRelevanceReference
" These effects of T3 microinjection to the preoptic region were demonstrated after acute injections and within hours of injection rather than after chronic administration over days."1.39Effects of acute microinjections of thyroid hormone to the preoptic region of hypothyroid adult male rats on sleep, motor activity and body temperature. ( Giannopoulos, PF; James, TD; Martin, JV; Moffett, SX, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moffett, SX1
Giannopoulos, PF1
James, TD1
Martin, JV2
Cooper-Kazaz, R1
Cohen, A1
Lerer, B1
McKenna, WJ1
Rowland, E1
Krikler, DM1
Samson, JA1
Mirin, SM1
Griffin, M1
Borrelli, D1
Schildkraut, JJ1
Joffe, RT1
Levitt, AJ1
Bagby, RM1
MacDonald, C1
Singer, W1
Zhang, SQ1

Reviews

1 review available for triiodothyronine and Sleep Wake Disorders

ArticleYear
Amiodarone: the experience of the past decade.
    British medical journal (Clinical research ed.), 1983, Dec-03, Volume: 287, Issue:6406

    Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Dose-Response Relationship, Drug; Drug Interactions;

1983

Other Studies

5 other studies available for triiodothyronine and Sleep Wake Disorders

ArticleYear
Effects of acute microinjections of thyroid hormone to the preoptic region of hypothyroid adult male rats on sleep, motor activity and body temperature.
    Brain research, 2013, Jun-21, Volume: 1516

    Topics: Analysis of Variance; Animals; Body Temperature; Disease Models, Animal; Electroencephalography; Ele

2013
Noradrenergic adverse effects due to combined treatment with reboxetine and triiodothyronine.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:2

    Topics: Adult; Depressive Disorder, Major; Drug Synergism; Drug Therapy, Combination; Humans; Male; Middle A

2010
Urinary MHPG and clinical symptoms in patients with unipolar depression.
    Psychiatry research, 1994, Volume: 51, Issue:2

    Topics: Adult; Body Weight; Cognition Disorders; Depressive Disorder; Dexamethasone; Female; Humans; Hydroco

1994
Predictors of response to lithium and triiodothyronine augmentation of antidepressants in tricyclic non-responders.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 163

    Topics: Adult; Ambulatory Care; Antidepressive Agents, Tricyclic; Double-Blind Method; Drug Resistance; Fema

1993
Basal forebrain microinjections of L-3,3',5-triiodothyronine modify sleep in hypothyroid rats.
    Psychiatry and clinical neurosciences, 2001, Volume: 55, Issue:3

    Topics: Animals; Body Temperature; Electroencephalography; Electromyography; Hypothyroidism; Male; Microinje

2001