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triiodothyronine and Retinoblastoma

triiodothyronine has been researched along with Retinoblastoma in 2 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)

Research Excerpts

ExcerptRelevanceReference
"Cycloheximide treatment suggested that the latter effect was due to increased initiation of translation."1.29Translational control of ornithine-delta-aminotransferase (OAT) by estrogen. ( Fagan, RJ; Rozen, R, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fagan, RJ2
Rozen, R2
Sheffield, WP1

Other Studies

2 other studies available for triiodothyronine and Retinoblastoma

ArticleYear
Translational control of ornithine-delta-aminotransferase (OAT) by estrogen.
    Molecular and cellular endocrinology, 1993, Volume: 90, Issue:2

    Topics: Alternative Splicing; Cycloheximide; Estradiol; Gene Expression Regulation, Enzymologic; Humans; Orn

1993
Regulation of ornithine aminotransferase in retinoblastomas.
    The Journal of biological chemistry, 1989, Dec-05, Volume: 264, Issue:34

    Topics: Blotting, Northern; Cell Line; Estradiol; Eye Neoplasms; Gene Expression Regulation, Enzymologic; Ge

1989