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triiodothyronine and Retinal Degeneration

triiodothyronine has been researched along with Retinal Degeneration in 4 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ma, H2
Thapa, A1
Morris, L1
Redmond, TM2
Baehr, W1
Ding, XQ2
Yang, F1
Belcher, J1
Butler, MR1
Boye, SL1
Hauswirth, WW1
ALBRIGHT, EC1
LARSON, FC1
DEISS, WP1
Baas, D1
Legrand, C1
Samarut, J1
Flamant, F1

Other Studies

4 other studies available for triiodothyronine and Retinal Degeneration

ArticleYear
Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Mar-04, Volume: 111, Issue:9

    Topics: Animals; Antithyroid Agents; cis-trans-Isomerases; Color Vision Defects; Cone Opsins; Cyclic Nucleot

2014
Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:12

    Topics: Animals; Cells, Cultured; Iodide Peroxidase; Mice, Knockout; Retina; Retinal Cone Photoreceptor Cell

2016
Single dimension chromatographic separation of thyroxin and triiodothyronine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1953, Volume: 84, Issue:1

    Topics: Chromatography; Rare Diseases; Retinal Degeneration; Retinal Detachment; Thyroxine; Triiodothyronine

1953
Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Mar-05, Volume: 99, Issue:5

    Topics: Animals; Animals, Newborn; Cell Differentiation; DNA-Binding Proteins; Mice; Mice, Inbred C57BL; Mic

2002