triiodothyronine has been researched along with Reperfusion Injury in 21 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "After 70% liver ischemia reperfusion injury, mice that were preconditioned with appropriate T3 displayed significantly preserved liver function, less histological damage, less apoptosis, and enhanced antioxidant capacity." | 5.42 | Tri-iodothyronine preconditioning protects against liver ischemia reperfusion injury through the regulation of autophagy by the MEK/ERK/mTORC1 axis. ( Fu, Z; Liu, F; Sui, M; Wang, QX; Wang, Y; Yang, J, 2015) |
| "Triiodothyronine (T3) is a known hepatic mitogen." | 5.38 | Triiodothyronine attenuates hepatic ischemia/reperfusion injury in a partial hepatectomy model through inhibition of proinflammatory cytokines, transcription factors, and adhesion molecules. ( Chen, KJ; He, Y; Taki-Eldin, A; Xie, HY; Yu, D; Zheng, SS; Zhou, L, 2012) |
| " The present study evaluated triiodothyronine (T3), thyroxine, and thyroid-stimulating hormone concentrations before and early after transplantation relative to the occurrence of delayed graft function." | 3.77 | Protective effect of low serum thyroid hormone concentration on occurrence of functional delayed kidney allograft function early after transplantation. ( Bonakdaran, S; Hekmat, R; Javadi, Z; Javain, ML, 2011) |
| "After 70% liver ischemia reperfusion injury, mice that were preconditioned with appropriate T3 displayed significantly preserved liver function, less histological damage, less apoptosis, and enhanced antioxidant capacity." | 1.42 | Tri-iodothyronine preconditioning protects against liver ischemia reperfusion injury through the regulation of autophagy by the MEK/ERK/mTORC1 axis. ( Fu, Z; Liu, F; Sui, M; Wang, QX; Wang, Y; Yang, J, 2015) |
| "Triiodothyronine (T3) is a known hepatic mitogen." | 1.38 | Triiodothyronine attenuates hepatic ischemia/reperfusion injury in a partial hepatectomy model through inhibition of proinflammatory cytokines, transcription factors, and adhesion molecules. ( Chen, KJ; He, Y; Taki-Eldin, A; Xie, HY; Yu, D; Zheng, SS; Zhou, L, 2012) |
| "Reperfusion injury was assessed by post-ischemic recovery of left ventricular developed pressure (LVDP%) and LDH release." | 1.37 | Acute T3 treatment protects the heart against ischemia-reperfusion injury via TRα1 receptor. ( Brozou, V; Cokkinos, DV; Galanopoulos, G; Kostopanagiotou, G; Mourouzis, I; Pantos, C; Saranteas, T, 2011) |
| "The effect of ischemia induced acute renal failure (ARF) on the transport of phosphate (Pi) after early (15-30 min) and prolonged (60 min) ischemia in the brush border membrane vesicles (BBMV) from rat renal cortex was studied." | 1.33 | Effect of ischemia reperfusion on sodium-dependent phosphate transport in renal brush border membranes. ( Asghar, M; Banday, AA; Khan, F; Khundmiri, SJ; Levi, M; Salim, S; Yusufi, AN, 2005) |
| "Isoproterenol caused an increase in the level of cyclic AMP (rho;moles/10(5) myocytes) in the control (from 2." | 1.32 | Effects of triiodothyronine pretreatment on beta-adrenergic responses in stunned cardiac myocytes. ( Gandhi, A; He, YQ; Tse, J; Weiss, HR; Yan, L, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 12 (57.14) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Doshi, M | 1 |
| Watanabe, S | 1 |
| Natori, Y | 1 |
| Hosoyamada, M | 1 |
| Hirashima-Akae, Y | 1 |
| Sabatino, L | 1 |
| Kusmic, C | 1 |
| Iervasi, G | 1 |
| Valenzuela, R | 2 |
| Videla, LA | 7 |
| Ferreyra, C | 1 |
| Vargas, F | 1 |
| Rodríguez-Gómez, I | 1 |
| Pérez-Abud, R | 1 |
| O'Valle, F | 1 |
| Osuna, A | 1 |
| Kim, SM | 1 |
| Kim, SW | 1 |
| Jung, YJ | 1 |
| Min, SI | 1 |
| Min, SK | 1 |
| Kim, SJ | 1 |
| Ha, J | 1 |
| Yang, J | 1 |
| Wang, Y | 1 |
| Sui, M | 1 |
| Liu, F | 1 |
| Fu, Z | 1 |
| Wang, QX | 1 |
| Li, Q | 1 |
| Qi, X | 1 |
| Jia, W | 1 |
| Pantos, C | 2 |
| Mourouzis, I | 2 |
| Saranteas, T | 2 |
| Clavé, G | 1 |
| Ligeret, H | 1 |
| Noack-Fraissignes, P | 1 |
| Renard, PY | 1 |
| Massonneau, M | 1 |
| Perimenis, P | 1 |
| Spanou, D | 1 |
| Kostopanagiotou, G | 2 |
| Cokkinos, DV | 2 |
| Fernández, V | 5 |
| Tapia, G | 5 |
| Varela, P | 3 |
| Cornejo, P | 1 |
| Santibáñez, C | 1 |
| Farías, J | 1 |
| Fuenzalida, G | 1 |
| Peng, PH | 1 |
| Chao, HM | 1 |
| Juan, SH | 1 |
| Chen, CF | 1 |
| Liu, JH | 1 |
| Ko, ML | 1 |
| Hekmat, R | 1 |
| Javadi, Z | 1 |
| Javain, ML | 1 |
| Bonakdaran, S | 1 |
| Brozou, V | 1 |
| Galanopoulos, G | 1 |
| Li, F | 1 |
| Lu, S | 1 |
| Zhu, R | 1 |
| Zhou, Z | 1 |
| Ma, L | 1 |
| Cai, L | 1 |
| Liu, Z | 1 |
| Mardones, M | 1 |
| Romanque, P | 2 |
| Covarrubias, N | 1 |
| Anghileri, F | 1 |
| Taki-Eldin, A | 1 |
| Zhou, L | 1 |
| Xie, HY | 1 |
| Chen, KJ | 1 |
| Yu, D | 1 |
| He, Y | 1 |
| Zheng, SS | 1 |
| Tse, J | 1 |
| Gandhi, A | 1 |
| Yan, L | 1 |
| He, YQ | 1 |
| Weiss, HR | 1 |
| Khundmiri, SJ | 1 |
| Asghar, M | 1 |
| Banday, AA | 1 |
| Khan, F | 1 |
| Salim, S | 1 |
| Levi, M | 1 |
| Yusufi, AN | 1 |
| Castillo, I | 1 |
| Uribe-Echevarría, S | 1 |
| Uribe, M | 1 |
| Cartier-Ugarte, D | 1 |
| Santander, G | 1 |
| Vial, MT | 2 |
| Gaete, L | 1 |
| Vera, G | 1 |
| Mora, C | 1 |
| Troncoso, P | 1 |
| Smok, G | 1 |
1 review available for triiodothyronine and Reperfusion Injury
| Article | Year |
|---|---|
Crosstalk mechanisms in hepatoprotection: Thyroid hormone-docosahexaenoic acid (DHA) and DHA-extra virgin olive oil combined protocols.
Topics: Animals; Diet, High-Fat; Docosahexaenoic Acids; Drug Therapy, Combination; Humans; Liver; Non-alcoho | 2018 |
20 other studies available for triiodothyronine and Reperfusion Injury
| Article | Year |
|---|---|
Triiodothyronine Aggravates Global Cerebral Ischemia-Reperfusion Injury in Mice.
Topics: Animals; Astrocytes; Brain Ischemia; Cell Death; Cerebral Infarction; Disease Models, Animal; DNA Fr | 2021 |
Modification of cardiac thyroid hormone deiodinases expression in an ischemia/reperfusion rat model after T3 infusion.
Topics: Animals; Disease Models, Animal; Heart; Infusions, Intravenous; Iodide Peroxidase; Male; Rats; Rats, | 2020 |
Preconditioning with triiodothyronine improves the clinical signs and acute tubular necrosis induced by ischemia/reperfusion in rats.
Topics: Animals; Biopsy; Glutathione; Immunohistochemistry; Inflammation; Interleukin-6; Ischemic Preconditi | 2013 |
Preconditioning with thyroid hormone (3,5,3-triiodothyronine) prevents renal ischemia-reperfusion injury in mice.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Cytokines; Drug Administration Schedule; In Situ Nick- | 2014 |
Tri-iodothyronine preconditioning protects against liver ischemia reperfusion injury through the regulation of autophagy by the MEK/ERK/mTORC1 axis.
Topics: Animals; Apoptosis; Autophagy; Liver; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; | 2015 |
3,3',5-triiodothyroxine inhibits apoptosis and oxidative stress by the PKM2/PKM1 ratio during oxygen-glucose deprivation/reperfusion AC16 and HCM-a cells: T3 inhibits apoptosis and oxidative stress by PKM2/PKM1 ratio.
Topics: Apoptosis; Carrier Proteins; Cell Line; Glucose; Humans; Iodide Peroxidase; Membrane Proteins; Myocy | 2016 |
Thyroid hormone improves postischaemic recovery of function while limiting apoptosis: a new therapeutic approach to support hemodynamics in the setting of ischaemia-reperfusion?
Topics: Animals; Apoptosis; Biomechanical Phenomena; Caspase 3; Disease Models, Animal; Gene Expression Regu | 2009 |
Upregulation of liver inducible nitric oxide synthase following thyroid hormone preconditioning: suppression by N-acetylcysteine.
Topics: Acetylcysteine; Animals; Free Radical Scavengers; Ischemic Preconditioning; Liver; Male; Nitric Oxid | 2009 |
Kupffer-cell activity is essential for thyroid hormone rat liver preconditioning.
Topics: Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; DNA; Gadolinium; Ischemic Preconditi | 2010 |
Pharmacological preconditioning by low dose cobalt protoporphyrin induces heme oxygenase-1 overexpression and alleviates retinal ischemia-reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Female; Hem | 2011 |
Protective effect of low serum thyroid hormone concentration on occurrence of functional delayed kidney allograft function early after transplantation.
Topics: Cross-Sectional Studies; Delayed Graft Function; Female; Humans; Kidney Failure, Chronic; Kidney Tra | 2011 |
Acute T3 treatment protects the heart against ischemia-reperfusion injury via TRα1 receptor.
Topics: Amiodarone; Animals; Dronedarone; Drug Synergism; Heart; In Vitro Techniques; Male; Myocardial Contr | 2011 |
Heme oxygenase-1 is induced by thyroid hormone and involved in thyroid hormone preconditioning-induced protection against renal warm ischemia in rat.
Topics: Animals; Gene Expression; Glutathione; Heme Oxygenase-1; Kidney; Kidney Tubules; Male; Malondialdehy | 2011 |
Prevention of liver ischemia reperfusion injury by a combined thyroid hormone and fish oil protocol.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Dietary Supplements; Fatty Acids, Om | 2012 |
Triiodothyronine attenuates hepatic ischemia/reperfusion injury in a partial hepatectomy model through inhibition of proinflammatory cytokines, transcription factors, and adhesion molecules.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Cell Adhesion Molecules; Cell | 2012 |
Effects of triiodothyronine pretreatment on beta-adrenergic responses in stunned cardiac myocytes.
Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Disease Models, Animal; Heart Ventricles; Isoproteren | 2003 |
Effect of ischemia reperfusion on sodium-dependent phosphate transport in renal brush border membranes.
Topics: Animals; Biological Transport; Blotting, Western; Cell Membrane; Ischemia; Kidney; Kidney Cortex; Ki | 2005 |
Thyroid hormone preconditioning: protection against ischemia-reperfusion liver injury in the rat.
Topics: Acute-Phase Reaction; Alanine Transaminase; Animals; Aspartate Aminotransferases; Gene Expression Re | 2007 |
Causal role of oxidative stress in liver preconditioning by thyroid hormone in rats.
Topics: Acetylcysteine; Animals; Aspartate Aminotransferases; Glutathione; Ischemic Preconditioning; Liver; | 2008 |
Potentiation of ischemia-reperfusion liver injury by hyperthyroidism in the rat.
Topics: Animals; Body Temperature; Body Weight; Glutathione; Histocytochemistry; Hyperthyroidism; L-Lactate | 1997 |