triiodothyronine has been researched along with Pulmonary Fibrosis in 5 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was therefore to evaluate the effect of propylthiouracil (PTU), and of the hypothyroidism induced by it, on the development of cutaneous and pulmonary fibrosis in the oxidant stress murine model of SSc." | 7.79 | Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. ( Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F, 2013) |
| "Triiodothyronine (T3) has been shown to exert a defensive role in many pulmonary diseases, however, rare data are available regarding the role of T3 on silica-induced injury." | 5.62 | Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice. ( Chen, W; Fan, L; Gan, S; Ma, J; Wang, B; Wang, D; Xie, Y; Yang, M; Yu, L, 2021) |
| " The aim of this study was therefore to evaluate the effect of propylthiouracil (PTU), and of the hypothyroidism induced by it, on the development of cutaneous and pulmonary fibrosis in the oxidant stress murine model of SSc." | 3.79 | Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. ( Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F, 2013) |
| "Triiodothyronine (T3) has been shown to exert a defensive role in many pulmonary diseases, however, rare data are available regarding the role of T3 on silica-induced injury." | 1.62 | Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice. ( Chen, W; Fan, L; Gan, S; Ma, J; Wang, B; Wang, D; Xie, Y; Yang, M; Yu, L, 2021) |
| "Infection is a frequent cause of death in patients receiving bone marrow transplants." | 1.26 | Defective neutrophil chemotaxis in bone marrow transplant patients. ( Clark, RA; Johnson, FL; Klebanoff, SJ; Thomas, ED, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, M | 1 |
| Wang, D | 1 |
| Gan, S | 1 |
| Wang, B | 1 |
| Yu, L | 1 |
| Xie, Y | 1 |
| Fan, L | 1 |
| Ma, J | 1 |
| Chen, W | 1 |
| Bagnato, G | 2 |
| Bitto, A | 1 |
| Irrera, N | 1 |
| Pizzino, G | 1 |
| Sangari, D | 1 |
| Cinquegrani, M | 1 |
| Roberts, W | 1 |
| Atteritano, M | 1 |
| Altavilla, D | 1 |
| Squadrito, F | 1 |
| Saitta, A | 1 |
| Clark, RA | 1 |
| Johnson, FL | 1 |
| Klebanoff, SJ | 1 |
| Thomas, ED | 1 |
| Foresti, V | 1 |
| Pepe, R | 1 |
| Parisio, E | 1 |
| De Filippi, G | 1 |
| Scolari, N | 1 |
| Frigerio, C | 1 |
| Tyree, EB | 1 |
| Glicksman, AS | 1 |
| Nickson, JJ | 1 |
5 other studies available for triiodothyronine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
Topics: Animals; Fibrosis; Inflammation; Lung; Mice; Mice, Inbred C57BL; Pneumonia; Pulmonary Fibrosis; Sili | 2021 |
Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis.
Topics: Actins; Animals; Antithyroid Agents; Blotting, Western; Disease Models, Animal; Extracellular Signal | 2013 |
Defective neutrophil chemotaxis in bone marrow transplant patients.
Topics: Acute Disease; Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Bone Ma | 1976 |
Angiotensin-converting enzyme as a possible marker for lung toxicity in amiodarone-treated patients.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Biomarkers; Female; Humans; Lung | 1989 |
Effect of l-triiodothyronine on radiation-induced pulmonary fibrosis in dogs.
Topics: Animals; Dogs; Male; Pulmonary Fibrosis; Radiation Injuries, Experimental; Respiratory Function Test | 1966 |