Page last updated: 2024-11-08

triiodothyronine and Pre-Eclampsia

triiodothyronine has been researched along with Pre-Eclampsia in 20 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.

Research Excerpts

ExcerptRelevanceReference
" Iodine deficiency in pregnancy, which is amenable to correction through iodine supplementation, has been reported to increase the risk of preeclampsia."8.12Iodine deficiency in pregnancy along a concentration gradient is associated with increased severity of preeclampsia in rural Eastern Cape, South Africa. ( Businge, CB; Kengne, AP; Longo-Mbenza, B, 2022)
"Serum concentrations of total and free thyroxine (T4 and FT4) and total and free triiodothyronine (T3 and FT3) were measured in normal pregnant women, in patients with toxemia of pregnancy, and in patients with gestational trophoblastic disease (GTD)."7.65Total and free thyroxine and triiodothyronine in normal and complicated pregnancy. ( Chopra, IJ; Osathanondh, R; Tulchinsky, D, 1976)
" Iodine deficiency in pregnancy, which is amenable to correction through iodine supplementation, has been reported to increase the risk of preeclampsia."4.12Iodine deficiency in pregnancy along a concentration gradient is associated with increased severity of preeclampsia in rural Eastern Cape, South Africa. ( Businge, CB; Kengne, AP; Longo-Mbenza, B, 2022)
"Pre-eclampsia is associated with lower serum selenium concentrations and glutathione peroxidase expression/activity; total thyroid hormones are also lower."3.79Thyroid hormones and their placental deiodination in normal and pre-eclamptic pregnancy. ( Broughton Pipkin, F; Kaptein, E; Kurlak, LO; Mistry, HD; Visser, TJ, 2013)
"Serum concentrations of total and free thyroxine (T4 and FT4) and total and free triiodothyronine (T3 and FT3) were measured in normal pregnant women, in patients with toxemia of pregnancy, and in patients with gestational trophoblastic disease (GTD)."3.65Total and free thyroxine and triiodothyronine in normal and complicated pregnancy. ( Chopra, IJ; Osathanondh, R; Tulchinsky, D, 1976)
"However, the exact role of preeclampsia in gestational hypothyroidism is still obscure."1.62Effect of Preeclampsia on Ultrastructure of Thyroid Gland, Hepatic Type 1 Iodothyronine Deiodinase, and Thyroid Hormone Levels in Rats. ( Jiang, W; Lan, M; Li, Y; Liu, Y; Wang, Y; Xie, X; Xu, Z, 2021)
"0."1.38The effect of the D1-C785T polymorphism in the type 1 iodothyronine deiodinase gene on the circulating thyroid hormone levels in Romanian women with preeclampsia. Association with the degree of severity and pregnancy outcome of preeclampsia. ( Caracostea, G; Dragatoiu, GH; Hazi, GM; Nemeti, G; Olteanu, I; Procopciuc, LM; Stamatian, F, 2012)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's2 (10.00)18.2507
2000's3 (15.00)29.6817
2010's6 (30.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Businge, CB1
Longo-Mbenza, B1
Kengne, AP1
Liu, Y1
Xu, Z1
Li, Y1
Jiang, W1
Lan, M1
Xie, X1
Wang, Y1
Kurlak, LO1
Mistry, HD1
Kaptein, E1
Visser, TJ1
Broughton Pipkin, F1
Akiibinu, MO1
Kolawole, TO1
Ekun, OA1
Akiibinu, SO1
Zhou, J2
Du, J2
Ma, B1
Liu, X2
Qiu, H1
Li, J1
Wang, X1
Li, W1
Qiao, C1
Shang, T1
Levine, RJ1
Vatten, LJ1
Horowitz, GL1
Qian, C1
Romundstad, PR1
Yu, KF1
Hollenberg, AN1
Hellevik, AI1
Asvold, BO1
Karumanchi, SA1
Ashoor, G1
Maiz, N1
Rotas, M1
Kametas, NA1
Nicolaides, KH1
Procopciuc, LM1
Hazi, GM1
Caracostea, G1
Nemeti, G1
Olteanu, I1
Dragatoiu, GH1
Stamatian, F1
Qublan, HS1
Al-Kaisi, IJ1
Hindawi, IM1
Hiasat, MS1
Awamleh, I1
Hamaideh, AH1
Abd-Alghani, I1
Sou'ub, RM1
Abu-Jassar, H1
Al-Maitah, M1
Larijani, B1
Marsoosi, V1
Aghakhani, S1
Moradi, A1
Hashemipour, S1
Göser, R1
Jaschonek, K1
Kindler, D1
Keller, E1
Schindler, AE1
Khaliq, F1
Singhal, U1
Arshad, Z1
Hossain, MM1
Osathanondh, R1
Tulchinsky, D1
Chopra, IJ1
Lao, TT3
Chin, RK3
Swaminathan, R2
Lam, YM2
Panesar, NS1
Kiyoshige, K1
Bélanger, R1
Bergeron, D1
Bellabarba, D1
Bédard, S1
Ayromlooi, J1
Zervoudakis, IA1
Sadaghat, A1

Other Studies

20 other studies available for triiodothyronine and Pre-Eclampsia

ArticleYear
Iodine deficiency in pregnancy along a concentration gradient is associated with increased severity of preeclampsia in rural Eastern Cape, South Africa.
    BMC pregnancy and childbirth, 2022, Feb-04, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Case-Control Studies; Female; Humans; Iodine; Maternal Nutritional Physiological

2022
Effect of Preeclampsia on Ultrastructure of Thyroid Gland, Hepatic Type 1 Iodothyronine Deiodinase, and Thyroid Hormone Levels in Rats.
    BioMed research international, 2021, Volume: 2021

    Topics: Animals; Female; Hypothyroidism; Iodide Peroxidase; Liver; NG-Nitroarginine Methyl Ester; Pre-Eclamp

2021
Thyroid hormones and their placental deiodination in normal and pre-eclamptic pregnancy.
    Placenta, 2013, Volume: 34, Issue:5

    Topics: Adult; Female; Fetal Blood; Gene Expression; Gestational Age; Humans; Iodide Peroxidase; Placenta; P

2013
Metabolic dysfunctions in Nigerian pre-eclamptics.
    Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:5

    Topics: Adult; Antioxidants; Blood Pressure; Body Mass Index; Body Weight; C-Reactive Protein; Case-Control

2013
[Thyroid hormone changes in women with pre-eclampsia and its relationship with the presence of pre-eclampsia].
    Zhonghua fu chan ke za zhi, 2014, Volume: 49, Issue:2

    Topics: Adult; Autoantibodies; Case-Control Studies; Female; Humans; Hypothyroidism; Middle Aged; Pre-Eclamp

2014
[Correlation between thyroid hormones and renal function in severe pre-eclampsia patients with hypothyroidism].
    Zhonghua fu chan ke za zhi, 2014, Volume: 49, Issue:11

    Topics: China; Creatinine; Female; Humans; Hypothyroidism; Kidney Function Tests; Pre-Eclampsia; Pregnancy;

2014
Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced thyroid function: nested case-control and population based study.
    BMJ (Clinical research ed.), 2009, Nov-17, Volume: 339

    Topics: Epidemiologic Methods; Female; Humans; Hypothyroidism; Pre-Eclampsia; Pregnancy; Pregnancy Complicat

2009
Maternal thyroid function at 11 to 13 weeks of gestation and subsequent development of preeclampsia.
    Prenatal diagnosis, 2010, Volume: 30, Issue:11

    Topics: Adult; Autoantibodies; Blood Pressure; Female; Humans; Hypothyroidism; Pre-Eclampsia; Pregnancy; Pre

2010
The effect of the D1-C785T polymorphism in the type 1 iodothyronine deiodinase gene on the circulating thyroid hormone levels in Romanian women with preeclampsia. Association with the degree of severity and pregnancy outcome of preeclampsia.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2012, Volume: 28, Issue:5

    Topics: Adult; Female; Humans; Iodide Peroxidase; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy;

2012
Severe pre-eclampsia and maternal thyroid function.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2003, Volume: 23, Issue:3

    Topics: Adult; Albuminuria; Blood Pressure; Case-Control Studies; Female; Gestational Age; Humans; Pre-Eclam

2003
Thyroid hormone alteration in pre-eclamptic women.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 18, Issue:2

    Topics: Adult; Case-Control Studies; Female; Humans; Pre-Eclampsia; Pregnancy; Severity of Illness Index; Th

2004
Plasma cAMP in normal and abnormal human pregnancy.
    Gynecologic and obstetric investigation, 1980, Volume: 11, Issue:5

    Topics: Abortion, Threatened; Cyclic AMP; Female; Fenoterol; Humans; Labor, Induced; Obstetric Labor, Premat

1980
Thyroid functions in pre-eclampsia and its correlation with maternal age, parity, severity of blood pressure and serum albumin.
    Indian journal of physiology and pharmacology, 1999, Volume: 43, Issue:2

    Topics: Adult; Age Factors; Blood Pressure; Female; Humans; Pre-Eclampsia; Pregnancy; Serum Albumin; Thyroid

1999
Total and free thyroxine and triiodothyronine in normal and complicated pregnancy.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:1

    Topics: Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Preg

1976
Maternal thyroid hormones and outcome of pre-eclamptic pregnancies.
    British journal of obstetrics and gynaecology, 1990, Volume: 97, Issue:1

    Topics: Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Pregnancy

1990
Birth weight and thyroxine-binding globulin in pre-eclampsia.
    Gynecologic and obstetric investigation, 1989, Volume: 28, Issue:1

    Topics: Alpha-Globulins; Birth Weight; Female; Humans; Pre-Eclampsia; Pregnancy; Proteinuria; Thyroxine; Thy

1989
Thyroid function in pre-eclampsia.
    British journal of obstetrics and gynaecology, 1988, Volume: 95, Issue:9

    Topics: Adult; Female; Humans; Infant, Newborn; Infant, Small for Gestational Age; Pre-Eclampsia; Pregnancy;

1988
[Thyroid function during pregnancy--specficity of value of the thyroid function test on the pregnant woman].
    Nihon Naibunpi Gakkai zasshi, 1969, May-20, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Basal Metabolism; Castration; Child; Cholesterol; Chromatography, Gel; Electropho

1969
[Role of TSH determination in thyroid diseases].
    L'union medicale du Canada, 1974, Volume: 103, Issue:4

    Topics: Female; Humans; Hyperthyroidism; Hypothyroidism; Pre-Eclampsia; Pregnancy; Radioimmunoassay; Thyroid

1974
Thyrotoxicosis in pregnancy.
    American journal of obstetrics and gynecology, 1973, Nov-15, Volume: 117, Issue:6

    Topics: Abortion, Spontaneous; Adolescent; Adult; Cesarean Section; Cholesterol; Female; Fetal Death; Gestat

1973