triiodothyronine has been researched along with Porphyrias in 7 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
Excerpt | Relevance | Reference |
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"The role of thyroid status in hexachlorobenzene (HBC) induced porphyria was studied in normal, thyroidectomized and thyroxine (T4) treated rats." | 7.69 | Effect of thyroidectomy and thyroxine on hexachlorobenzene induced porphyria. ( Ferramola de Sancovich, AM; Kleiman de Pisarev, DL; Sancovich, HA; Sopena de Kracoff, YE, 1994) |
"The effects of hexachlorobenzene (HCB) administration on the development of porphyria and on changes in thyroid function and thyroid hormone metabolism were examined." | 7.68 | Thyroid function and thyroxine metabolism in hexachlorobenzene-induced porphyria. ( Kleiman de Pisarev, DL; Rios de Molina, MC; San Martin de Viale, LC, 1990) |
"1% hexachlorobenzene (HCB) for 55 days on mortality, body weight, urinary porphyrin excretion, serum thyroid hormones and induction of liver microsomal enzymes was studied in female Sprague-Dawley rats." | 7.67 | Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria. ( Gorski, JR; Parkinson, A; Rozman, K; Rozman, P, 1986) |
"The role of thyroid status in hexachlorobenzene (HBC) induced porphyria was studied in normal, thyroidectomized and thyroxine (T4) treated rats." | 3.69 | Effect of thyroidectomy and thyroxine on hexachlorobenzene induced porphyria. ( Ferramola de Sancovich, AM; Kleiman de Pisarev, DL; Sancovich, HA; Sopena de Kracoff, YE, 1994) |
"The effects of hexachlorobenzene (HCB) administration on the development of porphyria and on changes in thyroid function and thyroid hormone metabolism were examined." | 3.68 | Thyroid function and thyroxine metabolism in hexachlorobenzene-induced porphyria. ( Kleiman de Pisarev, DL; Rios de Molina, MC; San Martin de Viale, LC, 1990) |
"1% hexachlorobenzene (HCB) for 55 days on mortality, body weight, urinary porphyrin excretion, serum thyroid hormones and induction of liver microsomal enzymes was studied in female Sprague-Dawley rats." | 3.67 | Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria. ( Gorski, JR; Parkinson, A; Rozman, K; Rozman, P, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (57.14) | 18.7374 |
1990's | 2 (28.57) | 18.2507 |
2000's | 1 (14.29) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
De Matteis, F | 1 |
Harvey, C | 1 |
Sopena de Kracoff, YE | 1 |
Ferramola de Sancovich, AM | 1 |
Sancovich, HA | 1 |
Kleiman de Pisarev, DL | 2 |
Brodie, MJ | 2 |
Goldberg, A | 2 |
Beastall, GH | 2 |
Yeo, PP | 2 |
Ratcliffe, JG | 2 |
Graham, DJ | 1 |
Ratcliffe, WA | 1 |
Rios de Molina, MC | 1 |
San Martin de Viale, LC | 1 |
Rozman, K | 1 |
Gorski, JR | 1 |
Rozman, P | 1 |
Parkinson, A | 1 |
Kappas, A | 1 |
Bradlow, HL | 1 |
Gillette, PN | 1 |
Gallagher, TF | 1 |
7 other studies available for triiodothyronine and Porphyrias
Article | Year |
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Inducing coproporphyria in rat hepatocyte cultures using cyclic AMP and cyclic AMP-releasing agents.
Topics: Aminolevulinic Acid; Animals; Cells, Cultured; Coproporphyrinogen Oxidase; Coproporphyrins; Cyclic A | 2005 |
Effect of thyroidectomy and thyroxine on hexachlorobenzene induced porphyria.
Topics: Animals; Carboxy-Lyases; Female; Hexachlorobenzene; Porphyrias; Rats; Rats, Wistar; Thyroidectomy; T | 1994 |
Abnormal thyroid function in symptomatic acute intermittent porphyria [proceedings].
Topics: Female; Humans; Hyperthyroidism; Porphyrias; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1977 |
Thyroid function in acute intermittent porphyria: a neurogenic cause of hyperthyroidism?
Topics: Adult; Female; Humans; Hyperthyroidism; Male; Porphyrias; Pregnancy; Thyroid Gland; Thyroxine; Triio | 1978 |
Thyroid function and thyroxine metabolism in hexachlorobenzene-induced porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Body Weight; Chlorobenzenes; Dose-Response Relationship, Drug | 1990 |
Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria.
Topics: Administration, Oral; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes; | 1986 |
Abnormal steroid hormone metabolism in the genetic liver disease acute intermittent porphyria.
Topics: Acyltransferases; Alcohols; Androstanes; Animals; Carbon Isotopes; Cell Line; Chick Embryo; Coenzyme | 1971 |