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triiodothyronine and Phenylketonurias

triiodothyronine has been researched along with Phenylketonurias in 3 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Phenylketonurias: A group of autosomal recessive disorders marked by a deficiency of the hepatic enzyme PHENYLALANINE HYDROXYLASE or less frequently by reduced activity of DIHYDROPTERIDINE REDUCTASE (i.e., atypical phenylketonuria). Classical phenylketonuria is caused by a severe deficiency of phenylalanine hydroxylase and presents in infancy with developmental delay; SEIZURES; skin HYPOPIGMENTATION; ECZEMA; and demyelination in the central nervous system. (From Adams et al., Principles of Neurology, 6th ed, p952).

Research Excerpts

ExcerptRelevanceReference
"Free triiodothyronine was higher in both patient groups than in control subjects, whereas free thyroxine was higher in the PKU patients only."1.31Antioxidant and thyroid hormone status in selenium-deficient phenylketonuric and hyperphenylalaninemic patients. ( Printzen, G; van Bakel, MM; Wermuth, B; Wiesmann, UN, 2000)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Bakel, MM1
Printzen, G1
Wermuth, B1
Wiesmann, UN1
Stewart, RM1
Hemli, S1
Daniels, GH1
Kolodny, EH1
Maloof, F1
Gjessing, LR1
Nishimura, T1
Borud, O1

Other Studies

3 other studies available for triiodothyronine and Phenylketonurias

ArticleYear
Antioxidant and thyroid hormone status in selenium-deficient phenylketonuric and hyperphenylalaninemic patients.
    The American journal of clinical nutrition, 2000, Volume: 72, Issue:4

    Topics: Adolescent; Adult; Antioxidants; Child; Child, Preschool; Diet, Protein-Restricted; Female; Glutathi

2000
The pituitary-thyroid axis in adults with phenylketonuria.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:6

    Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Phenylketonurias; Pituitary Gland; Thyroid Gla

1976
Studies on urinary phenolic compounds in man. I. Excretion of p-hydroxy-mandelic acid by man.
    Scandinavian journal of clinical and laboratory investigation, 1965, Volume: 17, Issue:5

    Topics: Amino Acid Metabolism, Inborn Errors; Chromatography; Disulfiram; Humans; In Vitro Techniques; Mande

1965