Page last updated: 2024-11-08

triiodothyronine and Parkinson Disease

triiodothyronine has been researched along with Parkinson Disease in 11 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"Cognitive deficits are common in Parkinson's disease (PD) patients."1.40Thyroid status and cognitive function in euthyroid patients with early Parkinson's disease. ( Cho, KH; Choi, KH; Choi, SM; Kim, BC; Kim, JT; Kim, MK; Lee, SH; Nam, TS; Park, MS, 2014)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199010 (90.91)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, SM1
Kim, BC1
Choi, KH1
Nam, TS1
Kim, JT1
Lee, SH1
Park, MS1
Kim, MK1
Cho, KH1
Lancranjan, I1
Martinez-Campos, A1
Giovannini, P1
Novelli, A1
Cocchi, D1
Caraceni, T1
Müller, EE1
Berger, JR1
Kelley, RE1
Geffner, DL1
Azukizawa, M1
Hershman, JM1
Nisula, BC1
Glaubiger, GA1
Louvet, JP1
Chase, N1
McCaul, JA1
Cassell, KJ1
Stern, GM1
Burrow, GN1
Spaulding, SW1
Donabedian, R1
Van Woert, M1
Ambani, L1
Bora, SS1
Radichevich, I1
Werner, SC1
Ban, Y1
Prange, AJ1
Morris, CE1
Hall, CD1
Weiss, EA1

Reviews

1 review available for triiodothyronine and Parkinson Disease

ArticleYear
The endocrine profile of bromocriptine: its application in endocrine diseases.
    Journal of neural transmission, 1981, Volume: 51, Issue:1-2

    Topics: Bromocriptine; Cushing Syndrome; Endocrine Glands; Growth Hormone; Hormones; Humans; Huntington Dise

1981

Trials

2 trials available for triiodothyronine and Parkinson Disease

ArticleYear
Letter: Intravenous thyrotrophin-releasing hormone in Parkinson's disease.
    Lancet (London, England), 1974, Apr-20, Volume: 1, Issue:7860

    Topics: Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Synergism; Drug Therapy, Combination; H

1974
Artifactual elevation of PBI from an iodinated dye used to stain medicinal capsules pink.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:9

    Topics: Bipolar Disorder; Blood Proteins; Capsules; Carbonates; Chromatography, Paper; Clinical Trials as To

1969

Other Studies

8 other studies available for triiodothyronine and Parkinson Disease

ArticleYear
Thyroid status and cognitive function in euthyroid patients with early Parkinson's disease.
    Dementia and geriatric cognitive disorders, 2014, Volume: 38, Issue:3-4

    Topics: Aged; Cognition; Cognitive Dysfunction; Executive Function; Female; Humans; Male; Middle Aged; Neuro

2014
Thyrotrophin and prolactin responses to thyrotrophin-releasing hormone in patients with Parkinson's disease.
    Acta endocrinologica, 1982, Volume: 99, Issue:3

    Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydraz

1982
Thyroid function in Parkinson disease.
    Neurology, 1981, Volume: 31, Issue:1

    Topics: Aged; Carbidopa; Humans; Hypothyroidism; Levodopa; Middle Aged; Parkinson Disease; Prospective Studi

1981
Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:2

    Topics: Depression, Chemical; Humans; Injections, Intravenous; Male; Myxedema; Parkinson Disease; Propylthio

1975
Effect of a large dose of thyrotrophin releasing factor on pituitary and thyroid function in patients with Parkinsonism.
    Clinical endocrinology, 1976, Volume: 5, Issue:6

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Parkinson Disease; Pituitary Gland; Prolactin; Thyro

1976
The effect of L-DOPA on the hypothalamic-pituitary-thyroid axis.
    Advances in neurology, 1974, Volume: 5

    Topics: Aged; Female; Humans; Hydroxybutyrates; Hypothalamus; Levodopa; Male; Middle Aged; Parkinson Disease

1974
[Circadian rhythm of thyroid hormones in the blood].
    Nihon Naibunpi Gakkai zasshi, 1972, Jul-20, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Aged; Circadian Rhythm; Diabetes Mellitus; Drug Hypersensitivity; Humans; Hyperth

1972
Liothyronine with levodopa in parkinsonism.
    JAMA, 1971, Sep-06, Volume: 217, Issue:10

    Topics: Animals; Dihydroxyphenylalanine; Drug Synergism; Humans; Parkinson Disease; Rats; Sodium; Triiodothy

1971