triiodothyronine has been researched along with Osteoarthritis of Knee in 2 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous study indicated that the increase of local bio-availability of 3'3'5-triiodothyronine (T3) influenced osteoarthritis (OA) initiation." | 3.91 | Abnormal thyroid hormone receptor signaling in osteoarthritic osteoblasts regulates microangiogenesis in subchondral bone. ( Li, L; Li, M; Pang, Y; Wan, Y; Wang, J; Yin, Z; Zhu, C, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, L | 1 |
| Li, M | 1 |
| Pang, Y | 1 |
| Wang, J | 1 |
| Wan, Y | 1 |
| Zhu, C | 1 |
| Yin, Z | 1 |
| Nagase, H | 1 |
| Nagasawa, Y | 1 |
| Tachida, Y | 1 |
| Sakakibara, S | 1 |
| Okutsu, J | 1 |
| Suematsu, N | 1 |
| Arita, S | 1 |
| Shimada, K | 1 |
2 other studies available for triiodothyronine and Osteoarthritis of Knee
| Article | Year |
|---|---|
Abnormal thyroid hormone receptor signaling in osteoarthritic osteoblasts regulates microangiogenesis in subchondral bone.
Topics: Aged; Aged, 80 and over; Animals; Bone and Bones; China; Chondrocytes; Female; Humans; Injections, I | 2019 |
Deiodinase 2 upregulation demonstrated in osteoarthritis patients cartilage causes cartilage destruction in tissue-specific transgenic rats.
Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Case-Control Studies; Chondrocytes; Gene Exp | 2013 |