triiodothyronine has been researched along with Obsessive-Compulsive Disorder in 4 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, 16 patients with obsessive-compulsive disorder (OCD) who had partially improved during at least 6 months of treatment with clomipramine were sequentially treated with triiodothyronine and lithium carbonate in an 8-week double-blind cross-over study." | 9.07 | A controlled comparison of adjuvant lithium carbonate or thyroid hormone in clomipramine-treated patients with obsessive-compulsive disorder. ( Bernstein, SE; Grover, GN; Hill, JL; L'Heureux, F; Murphy, DL; Pato, MT; Pigott, TA, 1991) |
| "Clomipramine treatment was associated with significant decreases in TSH and T3 concentrations." | 6.71 | Elevated thyroid indices in children and adolescents with obsessive-compulsive disorder: effects of clomipramine treatment. ( Hanna, GL; McCracken, JT, 2005) |
| "In this study, 16 patients with obsessive-compulsive disorder (OCD) who had partially improved during at least 6 months of treatment with clomipramine were sequentially treated with triiodothyronine and lithium carbonate in an 8-week double-blind cross-over study." | 5.07 | A controlled comparison of adjuvant lithium carbonate or thyroid hormone in clomipramine-treated patients with obsessive-compulsive disorder. ( Bernstein, SE; Grover, GN; Hill, JL; L'Heureux, F; Murphy, DL; Pato, MT; Pigott, TA, 1991) |
| "Clomipramine treatment was associated with significant decreases in TSH and T3 concentrations." | 2.71 | Elevated thyroid indices in children and adolescents with obsessive-compulsive disorder: effects of clomipramine treatment. ( Hanna, GL; McCracken, JT, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Savaheli, S | 1 |
| Ahmadiani, A | 1 |
| McCracken, JT | 1 |
| Hanna, GL | 1 |
| Pigott, TA | 1 |
| Pato, MT | 1 |
| L'Heureux, F | 1 |
| Hill, JL | 1 |
| Grover, GN | 1 |
| Bernstein, SE | 1 |
| Murphy, DL | 1 |
| Chopra, IJ | 1 |
| Solomon, DH | 1 |
| Huang, TS | 1 |
1 review available for triiodothyronine and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Obsessive-compulsive disorder and growth factors: A comparative review.
Topics: Animals; Cognition; Humans; Insulin; Insulin-Like Growth Factor I; Intercellular Signaling Peptides | 2019 |
2 trials available for triiodothyronine and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Elevated thyroid indices in children and adolescents with obsessive-compulsive disorder: effects of clomipramine treatment.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Child; Clomipramine; Female; Humans; Hypothalamo-Hypop | 2005 |
A controlled comparison of adjuvant lithium carbonate or thyroid hormone in clomipramine-treated patients with obsessive-compulsive disorder.
Topics: Adult; Clomipramine; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Electrocardiog | 1991 |
1 other study available for triiodothyronine and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Serum thyrotropin in hospitalized psychiatric patients: evidence for hyperthyrotropinemia as measured by an ultrasensitive thyrotropin assay.
Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Dementia; Depression; Female; Humans; Male; Mental | 1990 |