triiodothyronine has been researched along with Obesity in 463 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Exenatide treatment reduced BMP-4 levels independent of weight loss." | 9.24 | New association of bone morphogenetic protein 4 concentrations with fat distribution in obesity and Exenatide intervention on it. ( Bu, L; Chen, J; Gao, J; Li, L; Qu, S; Rampersad, S; Wang, X; Zhu, CL, 2017) |
| "In this randomized controlled intervention, iodine-deficient, overweight or obese Moroccan women (n = 163) received 200 μg oral iodine or a placebo daily for 6 mo." | 9.20 | Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial. ( Aboussad, A; Chabaa, L; Cherkaoui, M; El Ansari, N; Herter-Aeberli, I; Rohner, R; Stinca, S; von Eckardstein, A; Zimmermann, MB, 2015) |
| " Objective To prospectively evaluate if administration of metformin to obese, diabetic patients with primary hypothyroidism on stable thyroxine replacement doses modifies TSH levels." | 9.12 | Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy. ( Cordido, F; Isidro, ML; Nemiña, R; Penín, MA, 2007) |
| "A prospective, randomised case-control trial of an anorectic drug, fenfluramine was conducted on 30 patients of simple obesity." | 9.07 | Effect of fenfluramine on serum T3, T4 and TSH levels in obesity. ( Agrawal, JK; Bajpai, HS; Bhatt, RP; Gupta, SS; Singh, SK, 1992) |
| "The anti-obesity thyroid hormone, triiodothyronine (T3), and irisin, an exercise- and/or cold-induced myokine, stimulate thermogenesis and energy consumption while decreasing lipid accumulation." | 8.31 | RNA-seq reveals that anti-obesity irisin and triiodothyronine (T3) hormones differentially affect the purinergic signaling transcriptomics in differentiated human adipocytes. ( Correia-de-Sá, P; Cury, SS; de Oliveira, M; Herman-de-Sousa, C; Mathias, LS; Nogueira, CR, 2023) |
| "The serum FT3 concentration and the C-peptide concentrations at five time points of the OGTT were significantly higher in the obesity group than in the non-obesity group." | 8.12 | Circulating free triiodothyronine concentration is positively associated with β-cell function in euthyroid patients with obesity and type 2 diabetes. ( Gong, L; Liang, K; Liu, J; Ma, A; Yin, X, 2022) |
| "Addition of levothyroxine to weight management interventions has no beneficial effect on BMI reduction as well as parameters of lipid and thyroid profiles, and should not be prescribed to children with obesity associated thyroid dysfunction." | 7.91 | Levothyroxine supplementation for obesity-associated thyroid dysfunction in children: a prospective, randomized, case control study. ( Attri, S; Bhalla, A; Dayal, D; Gupta, A; Kumar, S, 2019) |
| " The aim of this study is to investigate whether serum free thyroxine (FT4) and/or thyrotropin (TSH) levels are associated with the efficacy of weight reduction therapy in obese patients." | 7.83 | Serum free thyroxine levels are associated with the efficacy of weight reduction therapy in obese female patients. ( Hashimoto, K; Kono, S; Muranaka, K; Odori, S; Ogawa, Y; Satoh-Asahara, N; Shimatsu, A; Tagami, T; Tanaka, M; Yamakage, H, 2016) |
| " The OB group showed weight gain, increased adiposity, insulin resistance, increased leptin levels and genotoxicity; T3 administration in OS animals led to an increase in genotoxicity and oxidative stress when compared with the OB group." | 7.79 | A comparative genotoxicity study of a supraphysiological dose of triiodothyronine (T₃) in obese rats subjected to either calorie-restricted diet or hyperthyroidism. ( Conde, SJ; Corrêa, CR; de Oliveira, M; De Sibio, MT; Ferreira, AL; Luvizotto, RA; Marino, J; Nogueira, CR; Olimpio, RM; Padovani, CR, 2013) |
| "Obesity increases the susceptibility to harbor AITD with an emerging role for leptin as a peripheral determinant, which needs to be confirmed in future investigations." | 7.76 | Investigations of thyroid hormones and antibodies in obesity: leptin levels are associated with thyroid autoimmunity independent of bioanthropometric, hormonal, and weight-related determinants. ( Aimaretti, G; De Medici, C; Di Blasio, A; Guzzaloni, G; Liuzzi, A; Marzullo, P; Minocci, A; Tagliaferri, MA, 2010) |
| " Aim of the study We sought to evaluate thyroid function and its possible relationship with body mass index (BMI), leptin, adiponectin and insulin sensitivity in euthyroid obese women." | 7.73 | Relationship of thyroid function with body mass index, leptin, insulin sensitivity and adiponectin in euthyroid obese women. ( Iacobellis, G; Iannucci, CV; Leonetti, F; Ribaudo, MC; Zappaterreno, A, 2005) |
| "We investigated the relationships of plasma leptin to levels of free thyroid hormones and TSH in 18 patients with newly diagnosed hyperthyroidism, 22 with newly diagnosed primary hypothyroidism, and 32 lean (body mass index [BMI] < 30) and 37 obese (BMI > 30 kg/m2) euthyroid subjects." | 7.70 | Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypothyroid and hyperthyroid subjects. ( Coppack, SW; Goodrick, SJ; Johnson, AB; Katz, J; Lightman, SL; Mohamed-Ali, V; Pinkney, JH, 1998) |
| "At baseline, there were significant correlations between plasma leptin and body mass index (BMI), fat-free mass (FFM) and insulin resistance." | 7.70 | Associations of leptin, insulin resistance and thyroid function with long-term weight loss in dieting obese men. ( Andersson, I; Degerblad, M; Hellström, PM; Kogner, P; Kral, JG; Näslund, E; Rössner, S, 2000) |
| "The plasma triiodothyronine (T3) and thyroxine (T4) ratios have been evaluated in kwashiorkor and diet-induced obese weaned rats." | 7.69 | Altered 3,5,3'-triiodothyronine thyroxine ratio in experimentally induced kwashiorkor and obesity in rats. ( Konji, VN; Lomo, PO; Makawiti, DW; Oloowokere, JO, 1995) |
| "3,5-Dimethyl-3'-isopropyl-L-thyronine (DIMIT) and 3,5-diiodo-3'-isopropylthyroacetic acid (IpTA2), two thyroid hormone analogs, have been tested in genetically obese Zucker rats and their lean littermates, in comparison with thyroxine (T4) and triiodothyronine (T3) for their thyromimetic activities on body weight gain and lipid levels in serum and liver." | 7.67 | Comparative effects of 3,5-dimethyl-3'-isopropyl-L-thyronine (DIMIT) and 3,5-diiodo-3'-isopropylthyroacetic acid (IpTA2) on body weight gain and lipid metabolism in genetically obese Zucker rats. ( Autissier, N; Dumas, P; Jorgensen, EC; Loireau, A; Michel, O; Michel, R, 1986) |
| " 4) Fasting reduced the levels of only certain serum proteins, interestingly TBG, transferrin, alpha 2-haptoglobin and complement C'3, all of which, except transferrin, are elevated in obesity." | 7.66 | Effects of obesity, total fasting and re-alimentation on L-thyroxine (T4), 3,5,3'-L-triiodothyronine (T3), 3,3',5'-L-triiodothyronine (rT3), thyroxine binding globulin (TBG), cortisol, thyrotrophin, cortisol binding globulin (CBG), transferrin, alpha 2-ha ( Bauer, M; Emmert, D; Fateh-Moghadam, A; Hofmann, GG; Horn, K; Pickardt, CR; Scriba, PC, 1979) |
| "Serum concentrations of free triiodothyronine (T3) and total T3 were measured in 25 grossly obese patients with constant body weight and no dietary restrictions." | 7.66 | Serum free triiodothyronine in obesity. ( Lindgreen, P; Stokholm, KH, 1982) |
| "The metabolic clearance and production rates of thyroxine (T4) and triiodothyronine (T3) were measured in 9 obese euthyroid patients prior to and during prolonged starvation." | 7.65 | Effect of starvation on the production and metabolism of thyroxine and triiodothyronine in euthyroid obese patients. ( Arky, RA; Braverman, LE; Ingbar, SH; O'Brian, JT; Portnay, GI; Rudolph, M; Vagenakis, AG, 1977) |
| " These findings uncover WAT as a viable target mediating the therapeutic benefits of TH and provide a safe and efficient therapeutic strategy for obesity and its complications by delivering TH to adipose tissue." | 5.72 | Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects. ( Chen, K; Cheong, LY; Feng, T; Gao, Y; Honoré, E; Hui, X; Jin, L; Lam, KSL; Wang, Q; Wang, W; Xu, A; Zhang, Y, 2022) |
| "Obesity has become a major public health problem, most commonly treated via dietary restriction to promote weight loss." | 5.36 | Administration of physiologic levels of triiodothyronine increases leptin expression in calorie-restricted obese rats, but does not influence weight loss. ( Cicogna, AC; Conde, SJ; Leopoldo, AS; Lima-Leopoldo, AP; Luvizotto, RA; Nascimento, AF; Nogueira, CR; Padovani, CR; Síbio, MT, 2010) |
| "Plethoryl is a combination of triatricol, cyclovalone and vitamin A normally prescribed in the treatment of hypercholesterolaemia." | 5.28 | [Probable side effects caused by plethoryl. Common acute hepatitis, anicteric hepatitis, cirrhosis due to hypervitaminosis A, inflammatory arthralgias]. ( Constantin, JM; Maroy, B; Moullot, P, 1989) |
| " Exenatide treatment reduced BMP-4 levels independent of weight loss." | 5.24 | New association of bone morphogenetic protein 4 concentrations with fat distribution in obesity and Exenatide intervention on it. ( Bu, L; Chen, J; Gao, J; Li, L; Qu, S; Rampersad, S; Wang, X; Zhu, CL, 2017) |
| "In this randomized controlled intervention, iodine-deficient, overweight or obese Moroccan women (n = 163) received 200 μg oral iodine or a placebo daily for 6 mo." | 5.20 | Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial. ( Aboussad, A; Chabaa, L; Cherkaoui, M; El Ansari, N; Herter-Aeberli, I; Rohner, R; Stinca, S; von Eckardstein, A; Zimmermann, MB, 2015) |
| " Objective To prospectively evaluate if administration of metformin to obese, diabetic patients with primary hypothyroidism on stable thyroxine replacement doses modifies TSH levels." | 5.12 | Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy. ( Cordido, F; Isidro, ML; Nemiña, R; Penín, MA, 2007) |
| "Dehydroepiandrosterone (DHEA) has been shown to have antiobesity activity in rodents and spontaneously obese dogs." | 5.08 | The effect of dehydroepiandrosterone combined with a low-fat diet in spontaneously obese dogs: a clinical trial. ( Kurzman, ID; MacEwen, EG; Miller, JB; Panciera, DL, 1998) |
| "A prospective, randomised case-control trial of an anorectic drug, fenfluramine was conducted on 30 patients of simple obesity." | 5.07 | Effect of fenfluramine on serum T3, T4 and TSH levels in obesity. ( Agrawal, JK; Bajpai, HS; Bhatt, RP; Gupta, SS; Singh, SK, 1992) |
| " Body weight and serum thyroxine (T4), T3 and reverse T3 (rT3) concentrations were measured before treatment, then monthly over 6 months." | 5.05 | Long-term evaluation of thyroidal response to partial calorie restriction in obesity. ( Black, EG; Del Cañizo-Gómez, FJ; Hoffenberg, R; Moreira-Andrés, MN, 1981) |
| "Overweight/obesity mediated the associations of MAFLD with triiodothyronine (T3), free triiodothyronine (FT3), free thyroxine (FT4), and the mediator accounted for 46." | 4.31 | The association between thyroid hormones and MAFLD is mediated by obesity and metabolic disorders and varies among MAFLD subtypes. ( Cao, L; Chen, X; Fan, H; Li, L; Liu, Z; Suo, C; Zhang, T, 2023) |
| " Autoimmune hypothyroidism is frequently associated with obesity, it is usually progressive and needs replacement treatment with L-thyroxine." | 4.12 | Possible added value of thyroglobulin antibody (TgAb) testing in the evaluation of thyroidal status of subjects with overweight or obesity. ( Basolo, A; Bechi Genzano, S; Ceccarini, G; Chiovato, L; Fierabracci, P; Rotondi, M; Salvetti, G; Santini, F; Scartabelli, G; Sotgia, G, 2022) |
| "The serum FT3 concentration and the C-peptide concentrations at five time points of the OGTT were significantly higher in the obesity group than in the non-obesity group." | 4.12 | Circulating free triiodothyronine concentration is positively associated with β-cell function in euthyroid patients with obesity and type 2 diabetes. ( Gong, L; Liang, K; Liu, J; Ma, A; Yin, X, 2022) |
| " Free triiodothyronine (fT3) and free thyroxine (fT4) levels were higher in obese women with class II obesity when compared to the control group." | 4.02 | Selenium status and its relationship with thyroid hormones in obese women. ( Feitosa, MM; Fontenelle, LC; Freitas, TEC; Henriques, GS; Marreiro, DDN; Moita Neto, JM; Morais, JBS; Oliveira, FE; Severo, JS, 2021) |
| "The aim of the study is to explore the independent association of free triiodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH) with hepatic steatosis and insulin resistance." | 4.02 | Independent associations of thyroid-related hormones with hepatic steatosis and insulin resistance in euthyroid overweight/obese Chinese adults. ( Chen, Y; Huang, B; Li, Z; Lin, M; Liu, C; Ma, D; Xiao, F; Yan, F; Ye, J; Zeng, J; Zeng, X; Zheng, X, 2021) |
| "Addition of levothyroxine to weight management interventions has no beneficial effect on BMI reduction as well as parameters of lipid and thyroid profiles, and should not be prescribed to children with obesity associated thyroid dysfunction." | 3.91 | Levothyroxine supplementation for obesity-associated thyroid dysfunction in children: a prospective, randomized, case control study. ( Attri, S; Bhalla, A; Dayal, D; Gupta, A; Kumar, S, 2019) |
| " This study aimed at evaluating the thyroid function and the effects of the triiodothyronine (T3) treatment on glycemia control, insulin sensitivity and subclinical inflammation in cafeteria-diet-induced obesity in rats." | 3.88 | Beneficial effects of thyroid hormone on adipose inflammation and insulin sensitivity of obese Wistar rats. ( Bargi-Souza, P; Nunes, MT; Panveloski-Costa, AC; Poyares, LL; Serrano-Nascimento, C; Viana, GS, 2018) |
| "Estrogen has been shown to affect metabolism and hemostasis in obesity and increases resting energy expenditure via leptin." | 3.88 | Relationship between estrogen and body composition, energy, and endocrine factors in obese women with normal and low REE. ( Ahmadi, S; Eshraghian, MR; Hedayati, M; Pishva, H, 2018) |
| " Detailed anthropometric measurements (including BMI and skinfold thickness) and fasting blood samples (for TSH, free thyroxine (FT4), free triiodothyronine (FT3), HbA1c, lipid profile, plasma glucose and insulin resistance (HOMA-IR) analysis) were obtained at 28 weeks gestation." | 3.83 | Maternal hypothyroxinaemia in pregnancy is associated with obesity and adverse maternal metabolic parameters. ( Hattersley, AT; Knight, BA; Shields, BM; Vaidya, B, 2016) |
| " The aim of this study is to investigate whether serum free thyroxine (FT4) and/or thyrotropin (TSH) levels are associated with the efficacy of weight reduction therapy in obese patients." | 3.83 | Serum free thyroxine levels are associated with the efficacy of weight reduction therapy in obese female patients. ( Hashimoto, K; Kono, S; Muranaka, K; Odori, S; Ogawa, Y; Satoh-Asahara, N; Shimatsu, A; Tagami, T; Tanaka, M; Yamakage, H, 2016) |
| " The OB group showed weight gain, increased adiposity, insulin resistance, increased leptin levels and genotoxicity; T3 administration in OS animals led to an increase in genotoxicity and oxidative stress when compared with the OB group." | 3.79 | A comparative genotoxicity study of a supraphysiological dose of triiodothyronine (T₃) in obese rats subjected to either calorie-restricted diet or hyperthyroidism. ( Conde, SJ; Corrêa, CR; de Oliveira, M; De Sibio, MT; Ferreira, AL; Luvizotto, RA; Marino, J; Nogueira, CR; Olimpio, RM; Padovani, CR, 2013) |
| "Our results suggest that T(3) modulate serum and gene expression levels of leptin, resistin, and adiponectin in experimental model of obesity, providing new insights regarding the relationship between T(3) and adipokines in obesity." | 3.78 | Experimental hyperthyroidism decreases gene expression and serum levels of adipokines in obesity. ( Cicogna, AC; Conde, SJ; de Síbio, MT; do Nascimento, AF; Leopoldo, AS; Lima-Leopoldo, AP; Luvizotto, Rde A; Nogueira, CR; Olímpio, RM, 2012) |
| " However, while it is unclear what the effects are of calorie restriction and high doses of triiodothyronine (T(3)) on adipokines in obesity, thyroid hormones are illicitly administered in isolation or in association with a hypocaloric diet as an obesity treatment." | 3.77 | Supraphysiological triiodothyronine doses diminish leptin and adiponectin gene expression, but do not alter resistin expression in calorie restricted obese rats. ( Cicogna, AC; Leopoldo, AS; Lima-Leopoldo, AP; Luvizotto, RA; Nascimento, AF; Nogueira, CR; Olímpio, RM; Padovani, CR; Síbio, MT, 2011) |
| " The treatment provoked a mobilization of triglycerides in the peripheral blood, a decrease of leptin and a loss of body weight." | 3.77 | Effects of long-term intraperitoneal injection of thyrotropin-releasing hormone (TRH) on aging- and obesity-related changes in body weight, lipid metabolism, and thyroid functions. ( Lesnikov, VA; Pierpaoli, W, 2011) |
| "Studies on thyroid function in obesity yielded inconsistent results; high thyroid-stimulating hormone (TSH) levels were generally shown; high free triiodothyronine (fT)-3 or fT4 levels were described in some, but not in other studies." | 3.76 | Weight loss through gastric banding: effects on TSH and thyroid hormones in obese subjects with normal thyroid function. ( Barbieri, M; Dall'Asta, C; Folli, F; Morabito, A; Paganelli, M; Paolisso, G; Pontiroli, AE; Vedani, P, 2010) |
| "Obesity increases the susceptibility to harbor AITD with an emerging role for leptin as a peripheral determinant, which needs to be confirmed in future investigations." | 3.76 | Investigations of thyroid hormones and antibodies in obesity: leptin levels are associated with thyroid autoimmunity independent of bioanthropometric, hormonal, and weight-related determinants. ( Aimaretti, G; De Medici, C; Di Blasio, A; Guzzaloni, G; Liuzzi, A; Marzullo, P; Minocci, A; Tagliaferri, MA, 2010) |
| " Rats raised in a small litter can develop hyperinsulinaemia, hyperphagia, hyperleptinaemia and hypertension as adults." | 3.75 | Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats. ( de Moura, EG; Dutra, SC; Lisboa, PC; Passos, MC; Rodrigues, AL, 2009) |
| " Additionally, leptin, insulin, and the insulin resistance index HOMA were analyzed in the obese and normal-weight girls." | 3.74 | Thyroid hormones and their relation to weight status. ( Andler, W; de Sousa, G; Dieffenbach, R; Isa, A; Reinehr, T, 2008) |
| " Aim of the study We sought to evaluate thyroid function and its possible relationship with body mass index (BMI), leptin, adiponectin and insulin sensitivity in euthyroid obese women." | 3.73 | Relationship of thyroid function with body mass index, leptin, insulin sensitivity and adiponectin in euthyroid obese women. ( Iacobellis, G; Iannucci, CV; Leonetti, F; Ribaudo, MC; Zappaterreno, A, 2005) |
| "We investigated the relationships of plasma leptin to levels of free thyroid hormones and TSH in 18 patients with newly diagnosed hyperthyroidism, 22 with newly diagnosed primary hypothyroidism, and 32 lean (body mass index [BMI] < 30) and 37 obese (BMI > 30 kg/m2) euthyroid subjects." | 3.70 | Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypothyroid and hyperthyroid subjects. ( Coppack, SW; Goodrick, SJ; Johnson, AB; Katz, J; Lightman, SL; Mohamed-Ali, V; Pinkney, JH, 1998) |
| "At baseline, there were significant correlations between plasma leptin and body mass index (BMI), fat-free mass (FFM) and insulin resistance." | 3.70 | Associations of leptin, insulin resistance and thyroid function with long-term weight loss in dieting obese men. ( Andersson, I; Degerblad, M; Hellström, PM; Kogner, P; Kral, JG; Näslund, E; Rössner, S, 2000) |
| " Six experiments were done: 1, definition of positive results for TgAA using samples from normal and T3 autoantibody (T3AA) positive dogs; 2, establishment of prevalence of positive results in 91 clinically normal dogs; 3, evaluation of positive results for sera from dogs with nonthyroidal illnesses; 4, testing of samples from dogs with primary hypothyroidism but absence of T4AA or T3AA, or both; 5, determination of prevalence of false-negative results in dogs that are T4AA and/or T3AA positive, which were (18 dogs) or were not (22 dogs) receiving L-thyroxine replacement therapy; and 6, examination of thyroid biopsy specimens from 18 dogs (8 TgAA positive and 10 TgAA negative)." | 3.70 | Prevalence of autoantibodies to thyroglobulin in dogs with nonthyroidal illness. ( Graham, PA; Hauptman, J; Nachreiner, RF; Refsal, KR; Watson, GL, 1998) |
| "The plasma triiodothyronine (T3) and thyroxine (T4) ratios have been evaluated in kwashiorkor and diet-induced obese weaned rats." | 3.69 | Altered 3,5,3'-triiodothyronine thyroxine ratio in experimentally induced kwashiorkor and obesity in rats. ( Konji, VN; Lomo, PO; Makawiti, DW; Oloowokere, JO, 1995) |
| " At 6 weeks of age, body weight, serum concentrations of thyroxine (T4), T3, insulin and glucose, oxygen consumption, colonic temperature, and body composition were analyzed." | 3.69 | Early treatment of obese (ob/ob) mice with triiodothyronine increases oxygen consumption and temperature and decreases body fat content. ( Kaplan, ML; Oh, SS, 1994) |
| "The thermogenic effect of a single oral dose of ephedrine (1 mg/kg body weight) was studied by indirect calorimetry in five women with 14% overweight before, during and 2 mo after 3 mo of chronic ephedrine treatment (20 mg, perorally, three times daily)." | 3.67 | Enhanced thermogenic responsiveness during chronic ephedrine treatment in man. ( Astrup, A; Christensen, NJ; Lundsgaard, C; Madsen, J, 1985) |
| "Serum total thyroxine (T4), 3,5,3'-triiodo-L-thyronine (T3), 3,3',5'-triiodo-L-thyronine (reverse T3 or rT3) and free thyroxine (FT4), free 3,5,3'-triiodo-L-thyronine (FT3) concentrations were measured by radioimmunoassay in 52 moderately obese patients and 32 age-matched control subjects with constant body weight and no dietary restriction." | 3.67 | Serum concentrations of total T4, T3, reverse T3 and free T4, T3 in moderately obese patients. ( Autissier, N; Chomard, P; Debry, G; Vernhes, G, 1985) |
| "Effects of degree of obesity on basal concentrations of insulin, glucose, thyroxine (T4), triiodothyronine (T3), estradiol-17 beta (E) and progesterone (P) were measured in serum from 50 estrous and 73 diestrous Holstein heifers and the insulin response to glucose infusion was assessed in diestrous obese (n = 7) and lean (n = 7) heifers." | 3.67 | Effects of obesity on insulin and glucose metabolism in cyclic heifers. ( McCann, JP; Reimers, TJ, 1986) |
| "3,5-Dimethyl-3'-isopropyl-L-thyronine (DIMIT) and 3,5-diiodo-3'-isopropylthyroacetic acid (IpTA2), two thyroid hormone analogs, have been tested in genetically obese Zucker rats and their lean littermates, in comparison with thyroxine (T4) and triiodothyronine (T3) for their thyromimetic activities on body weight gain and lipid levels in serum and liver." | 3.67 | Comparative effects of 3,5-dimethyl-3'-isopropyl-L-thyronine (DIMIT) and 3,5-diiodo-3'-isopropylthyroacetic acid (IpTA2) on body weight gain and lipid metabolism in genetically obese Zucker rats. ( Autissier, N; Dumas, P; Jorgensen, EC; Loireau, A; Michel, O; Michel, R, 1986) |
| "Changes in thyroid hormone metabolism in the low-3,5,3'-triiodothyronine (T3) syndrome cannot be fully explained in all conditions by a decrease in 5'-deiodinase activity." | 3.67 | Effects of caloric deprivation on thyroid hormone tissue uptake and generation of low-T3 syndrome. ( Docter, R; Hennemann, G; Krenning, EP; van der Heyden, JT; van Toor, H; Wilson, JH, 1986) |
| "Body weight gain, food intake and serum concentrations of total lipids, cholesterol, triglycerides, phospholipids and free fatty acids were measured in genetically obese and lean female Zucker rats after surgical thyroidectomy and treatment with 3,5,3'-triiodothyronine (T3) (3 micrograms/100 g body wt per day) for 4 wk." | 3.67 | Influence of thyroid status on body weight gain, food intake and serum lipid levels in genetically obese Zucker rats. ( Autissier, N; Dumas, P; Loireau, A; Michel, R, 1987) |
| "Levels of circulating estrone (E1), estradiol (E2), androst-4-ene-3,17-dione (Adione), 3,5,3'-triiodothyronine (T3), thyroxine (T4), and sex hormone-binding globulin (SHBG) were measured in 10 obese postmenopausal patients with breast cancer and in 10 obese postmenopausal control subjects matched for age, body size, and menopausal status." | 3.67 | Decrease of circulating level of SHBG in postmenopausal obese women as a risk factor in breast cancer: reversible effect of weight loss. ( Cardillo, LR; del Carmen Cremona, M; Enriori, CL; Etkin, AE; Orsini, W; Reforzo-Membrives, J, 1986) |
| "We studied plasma concentrations of TSH (basal and after TRH), thyroxine (T4), 3,5,3'-triiodothyronine (T3), 3,3',5'-triiodothyronine (reverse T3; rT3), free T4 and free T3 in thirty obese subjects, twenty patients with anorexia nervosa, fifteen malnourished subjects and twenty normal weight subjects." | 3.66 | Thyroid function in altered nutritional state. ( Corsello, SM; de Rosa, E; de Rosa, G; Della Casa, S; Pasargiklian, E; Ruffilli, MP, 1983) |
| "Serum concentrations of free triiodothyronine (T3) and total T3 were measured in 25 grossly obese patients with constant body weight and no dietary restrictions." | 3.66 | Serum free triiodothyronine in obesity. ( Lindgreen, P; Stokholm, KH, 1982) |
| " 4) Fasting reduced the levels of only certain serum proteins, interestingly TBG, transferrin, alpha 2-haptoglobin and complement C'3, all of which, except transferrin, are elevated in obesity." | 3.66 | Effects of obesity, total fasting and re-alimentation on L-thyroxine (T4), 3,5,3'-L-triiodothyronine (T3), 3,3',5'-L-triiodothyronine (rT3), thyroxine binding globulin (TBG), cortisol, thyrotrophin, cortisol binding globulin (CBG), transferrin, alpha 2-ha ( Bauer, M; Emmert, D; Fateh-Moghadam, A; Hofmann, GG; Horn, K; Pickardt, CR; Scriba, PC, 1979) |
| " Several major conclusions are justified from the data obtained: (1) Although the hepatic specific activity of fatty acid synthetase is higher in obese than in non obese animals pair-fed chow, no difference in hepatic activities is apparent in animals pair-fed the fat-free diet; (2) The higher enzymatic activity in obese animals fed chow is related to a higher content of enzyme, and this higher content is associated with a higher rate of enzyme synthesis; (3) The decrease in hepatic synthetase activity with starvation is distinctly more striking in non obese than in obese animals, and the changes in activity reflect changes in content of enzyme; (4) With starvation there is a decrease in synthesis of enzyme in obese and non obese animals, but only in non obese animals is there also a marked increase in the rate of synthetase degradation (t1/2 = 24 h during starvation, t1/2 = 76 h during normalfeeding); (5) Refeeding starved mice a fat-free diet results in a more striking increase in hepatic synthetase activity in non obese than in obese animals; (6) Administration of triiodothyronine causes a more marked increase in hepatic synthetase activity in non obese than in obese animals." | 3.65 | Regulation of hepatic fatty acid synthetase in the obese-hyperglycemic mutant mouse. ( Marasa, JC; Volpe, JJ, 1975) |
| "The metabolic clearance and production rates of thyroxine (T4) and triiodothyronine (T3) were measured in 9 obese euthyroid patients prior to and during prolonged starvation." | 3.65 | Effect of starvation on the production and metabolism of thyroxine and triiodothyronine in euthyroid obese patients. ( Arky, RA; Braverman, LE; Ingbar, SH; O'Brian, JT; Portnay, GI; Rudolph, M; Vagenakis, AG, 1977) |
| "Many patients treated for primary hypothyroidism have an unexplained reduced quality of life (QOL)." | 2.80 | Quality of life in patients with primary hypothyroidism related to BMI. ( Berghout, A; Kelderman-Bolk, N; Tijssen, JP; Visser, TJ, 2015) |
| "Reduced insulin sensitivity is associated with augmented TSH and fT(4), while progressive central fat accumulation is strictly related to a parallel increase in fT(3) levels, independently from total body fat." | 2.77 | Thyroid function tests in obese prepubertal children: correlations with insulin sensitivity and body fat distribution. ( Barbetti, F; Brufani, C; Cappa, M; Fintini, D; Manco, M; Nobili, V, 2012) |
| "Weight loss was 9." | 2.74 | Contribution of individual organ mass loss to weight loss-associated decline in resting energy expenditure. ( Bosy-Westphal, A; Glüer, CC; Goele, K; Heller, M; Heymsfield, SB; Hitze, B; Kossel, E; Later, W; Müller, MJ; Settler, U, 2009) |
| "Leptin seems to be a promising link between obesity and alterations of thyroid hormones since leptin concentrations influence TSH release." | 2.46 | Obesity and thyroid function. ( Reinehr, T, 2010) |
| "Obesity is associated with several endocrine diseases, including common ones such as hypothyroidism and polycystic ovarian syndrome to rare ones such as Cushing's syndrome, central hypothyroidism and hypothalamic disorders." | 2.44 | Classical endocrine diseases causing obesity. ( Weaver, JU, 2008) |
| " These findings uncover WAT as a viable target mediating the therapeutic benefits of TH and provide a safe and efficient therapeutic strategy for obesity and its complications by delivering TH to adipose tissue." | 1.72 | Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects. ( Chen, K; Cheong, LY; Feng, T; Gao, Y; Honoré, E; Hui, X; Jin, L; Lam, KSL; Wang, Q; Wang, W; Xu, A; Zhang, Y, 2022) |
| "Obesity is closely related to thyroid hormones; however, the relationship between abdominal fat distribution and thyroid hormones has rarely been explored." | 1.56 | Association between Abdominal Fat Distribution and Free Triiodothyronine in a Euthyroid Population. ( Bao, Y; Ma, X; Nie, X; Wang, Y; Xiao, Y; Xu, Y, 2020) |
| "Thyroid function and type 2 diabetes mellitus (T2DM) are both associated with increased risks of adverse clinical outcomes in nonalcoholic fatty liver disease (NAFLD)." | 1.56 | Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients. ( Huang, B; Yang, S; Ye, S, 2020) |
| "Maternal obesity is a risk factor for offspring obesity." | 1.46 | Thyroid Hormone-Dependent Epigenetic Regulation of Melanocortin 4 Receptor Levels in Female Offspring of Obese Rats. ( Kisliouk, T; Marco, A; Meiri, N; Tabachnik, T; Weller, A, 2017) |
| "Moreover, hyperinsulinemia reduces the circulating level of serum T4 and conversion of T4 to T3, mimicking hypothyroidism, because thyroid hormones are necessary for the maturation of chondrocytes." | 1.46 | Serum insulin in pathogenesis and treatment of osteoarthritis. ( Askari, A; Bahramali, E; Ehrampoush, E; Farjam, M; Homayounfar, R, 2017) |
| "Obesity is associated with alterations in thyroid hormone (TH) levels in obese, pregnant individuals." | 1.43 | Increasing maternal obesity is associated with alterations in both maternal and neonatal thyroid hormone levels. ( Aagaard, KM; Antony, KM; DelBeccaro, M; Hu, M; Kahr, MK; Suter, MA, 2016) |
| "Hypothyroidism was considered at a thyroid stimulating hormone level ≥ 4." | 1.43 | FT3/FT4 ratio predicts non-alcoholic fatty liver disease independent of metabolic parameters in patients with euthyroidism and hypothyroidism. ( Ahbab, S; Ataoğlu, HE; Çetin, F; Gökmen, FY; Mamaç, RY; Türker, BÇ; Türker, F; Yenigün, M, 2016) |
| "NAFLD was diagnosed by conventional ultrasound examination." | 1.40 | Thyroid hormone levels in obese children and adolescents with non-alcoholic fatty liver disease. ( Aydın, S; Cesur, Y; Gökçe, S; Özgen, IT; Torun, E, 2014) |
| "Obesity and metabolic syndrome are major health problems worldwide, including Turkey." | 1.38 | Association of metabolic syndrome parameters with TT3 and FT3/FT4 ratio in obese Turkish population. ( Abanonu, GB; Tarcin, O; Yazici, D, 2012) |
| "Obesity has been recognized as an independent risk factor for arterial hypertension." | 1.37 | Arterial hypertension in obesity: relationships with hormone and anthropometric parameters. ( De Pergola, G; Guida, P; Nardecchia, A; Silvestris, F, 2011) |
| "Severely obese individuals may need higher LT4 suppressive or replacement doses than normal-weight individuals due, among other factors, to impaired LT4 pharmacokinetic parameters." | 1.37 | Impaired pharmacokinetics of levothyroxine in severely obese volunteers. ( Faltaka, A; Gkotsina, MI; Kalfarentzos, F; Mamali, I; Markantes, GK; Markou, KB; Michalaki, MA; Vagenakis, AG, 2011) |
| "Obesity has become a major public health problem, most commonly treated via dietary restriction to promote weight loss." | 1.36 | Administration of physiologic levels of triiodothyronine increases leptin expression in calorie-restricted obese rats, but does not influence weight loss. ( Cicogna, AC; Conde, SJ; Leopoldo, AS; Lima-Leopoldo, AP; Luvizotto, RA; Nascimento, AF; Nogueira, CR; Padovani, CR; Síbio, MT, 2010) |
| "Obesity is frequently associated with modifications of thyroid size and function." | 1.36 | Thyroid function in obese children and adolescents. ( Carta, D; Casini, MR; Civolani, P; Loche, S; Marras, V; Pilia, S; Porcu, M; Uccheddu, AP, 2010) |
| "Treatment with propylthiouracil produced a decline in serum T3 plasma appearance rate T3 PAR (-55%; P < 0." | 1.29 | Impaired peripheral thyroid hormone metabolism in genetic obesity. ( Katzeff, HL; Selgrad, C, 1993) |
| "Elderly men with NIDDM had even lower serum testosterone levels compared with elderly men without NIDDM." | 1.29 | Hormonal changes in elderly men with non-insulin-dependent diabetes mellitus and the hormonal relationships to abdominal adiposity. ( Chang, TC; Hsiao, YL; Tung, CC, 1994) |
| "Triiodothyronine treatment in ob/ob mice resulted in lower values for body weight, liver weight, hepatocyte number, liver protein, epididymal fat pad weight, and white adipocyte number and size than in saline-treated ob/ob mice." | 1.29 | Early treatment of obese (ob/ob) mice with triiodothyronine increases oxidative metabolism in muscle but not in brown adipose tissue or liver. ( Kaplan, ML; Oh, SS, 1995) |
| "Mean body weight loss was 6 +/- 1." | 1.28 | Resting metabolic rate, body composition and thyroid hormones. Short term effects of very low calorie diet. ( Armellini, F; Bosello, O; Cavallo, E; Milani, MP; Vicentini, R; Zamboni, M, 1990) |
| "Plethoryl is a combination of triatricol, cyclovalone and vitamin A normally prescribed in the treatment of hypercholesterolaemia." | 1.28 | [Probable side effects caused by plethoryl. Common acute hepatitis, anicteric hepatitis, cirrhosis due to hypervitaminosis A, inflammatory arthralgias]. ( Constantin, JM; Maroy, B; Moullot, P, 1989) |
| "Drastic methods for the treatment of obesity are critically reviewed." | 1.26 | [Obesity: state of research and therapy]. ( Berchtold, P; Berger, M; Gries, FA; Zimmermann, H, 1980) |
| " 3) A controlled trial of physiologic doses of T3, such as 40 mu g/day, seems indicated, as opposed to pharmacologic dosed of T3 used by previous investigators." | 1.26 | Metabolic insufficiency as a limiting factor in the dietetic treatment of obesity. ( Boukis, M; Kitsopanides, J; Koutras, DA; Moulopoulos, SD; Piperingos, GD; Sfontouris, J; Souvatzoglou, A, 1981) |
| "The biguanides were a therapeutic enrichment particularly in the treatment of adipose elderly diabetics with obligatory diet." | 1.26 | [Indications and results of an additional differentiated pharmacotherapy of obesity]. ( Kucher, E, 1978) |
| "Treatment with triiodothyronine enhanced the activity of the mitochondrial sn-glycerol-3-phosphate dehydrogenase but did not affect the cytoplasmic enzyme." | 1.25 | Effect of diet and triiodothyronine on the activity of sn-glycerol-3-phosphate dehydrogenase and on the metabolism of glucose and pyruvate by adipose tissue of obese patients. ( Bray, GA, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 253 (54.64) | 18.7374 |
| 1990's | 66 (14.25) | 18.2507 |
| 2000's | 51 (11.02) | 29.6817 |
| 2010's | 70 (15.12) | 24.3611 |
| 2020's | 23 (4.97) | 2.80 |
| Authors | Studies |
|---|---|
| Yildirim, AM | 1 |
| Koca, AO | 1 |
| Beyan, E | 1 |
| Dogan, O | 1 |
| Karakaya, S | 1 |
| Aksoz, Z | 1 |
| Ertuğrul, DT | 1 |
| Ma, D | 1 |
| Zeng, J | 1 |
| Huang, B | 2 |
| Yan, F | 1 |
| Ye, J | 1 |
| Chen, Y | 2 |
| Zeng, X | 1 |
| Zheng, X | 1 |
| Xiao, F | 1 |
| Lin, M | 1 |
| Liu, C | 1 |
| Li, Z | 1 |
| Chen, YT | 1 |
| Yang, QY | 1 |
| Hu, Y | 1 |
| Liu, XD | 1 |
| de Avila, JM | 1 |
| Zhu, MJ | 1 |
| Nathanielsz, PW | 1 |
| Du, M | 1 |
| Merchan-Ramirez, E | 1 |
| Sanchez-Delgado, G | 1 |
| Arrizabalaga-Arriazu, C | 1 |
| Acosta, FM | 1 |
| Arias-Tellez, MJ | 1 |
| Muñoz-Torres, M | 1 |
| Garcia-Lario, JV | 1 |
| Llamas-Elvira, JM | 1 |
| Ruiz, JR | 1 |
| Birck, MG | 1 |
| Almeida-Pititto, B | 1 |
| Janovsky, CCPS | 1 |
| Goulart, AC | 1 |
| Santos, IS | 1 |
| Teixeira, PFDS | 1 |
| Sgarbi, JA | 1 |
| Barreto, SM | 1 |
| Duncan, BB | 1 |
| Schmidt, MI | 1 |
| Lotufo, PA | 1 |
| Bensenor, IM | 1 |
| Fierabracci, P | 1 |
| Basolo, A | 1 |
| Scartabelli, G | 1 |
| Bechi Genzano, S | 1 |
| Salvetti, G | 1 |
| Sotgia, G | 1 |
| Rotondi, M | 1 |
| Chiovato, L | 1 |
| Ceccarini, G | 1 |
| Santini, F | 1 |
| Wang, Y | 2 |
| Lu, S | 1 |
| Xu, X | 1 |
| Zhang, L | 3 |
| Yang, J | 1 |
| Hu, W | 1 |
| Gong, L | 1 |
| Ma, A | 1 |
| Yin, X | 1 |
| Liang, K | 1 |
| Liu, J | 2 |
| Lisowska-Myjak, B | 1 |
| Zborowska, H | 1 |
| Białek, S | 1 |
| Wroczyński, P | 1 |
| Kuch, M | 1 |
| Skarżyńska, E | 1 |
| Corica, D | 2 |
| Licenziati, MR | 2 |
| Calcaterra, V | 2 |
| Currò, M | 2 |
| Di Mento, C | 2 |
| Curatola, S | 2 |
| Zuccotti, G | 2 |
| Alibrandi, A | 2 |
| Ientile, R | 2 |
| Aversa, T | 2 |
| Wasniewska, M | 2 |
| Fan, H | 1 |
| Li, L | 2 |
| Liu, Z | 1 |
| Cao, L | 1 |
| Chen, X | 1 |
| Suo, C | 1 |
| Zhang, T | 1 |
| Chen, K | 1 |
| Cheong, LY | 2 |
| Gao, Y | 1 |
| Zhang, Y | 1 |
| Feng, T | 1 |
| Wang, Q | 1 |
| Jin, L | 1 |
| Honoré, E | 1 |
| Lam, KSL | 1 |
| Wang, W | 1 |
| Hui, X | 1 |
| Xu, A | 2 |
| Mathias, LS | 1 |
| Herman-de-Sousa, C | 1 |
| Cury, SS | 1 |
| Nogueira, CR | 5 |
| Correia-de-Sá, P | 1 |
| de Oliveira, M | 2 |
| Wojciechowska, M | 1 |
| Wisniewski, OW | 1 |
| Pruszynska-Oszmalek, E | 1 |
| Krauss, H | 1 |
| Sassek, M | 1 |
| Leciejewska, N | 1 |
| Kolodziejski, P | 1 |
| Wilczak, M | 1 |
| Neves, JS | 1 |
| Leite, AR | 1 |
| Conceição, G | 1 |
| Gonçalves, A | 1 |
| Borges-Canha, M | 1 |
| Vale, C | 1 |
| Von-Hafe, M | 1 |
| Martins, D | 1 |
| Miranda-Silva, D | 1 |
| Leite, S | 1 |
| Rocha-Oliveira, E | 1 |
| Sousa-Mendes, C | 1 |
| Chaves, J | 1 |
| Lourenço, IM | 1 |
| Grijota-Martínez, C | 1 |
| Bárez-López, S | 1 |
| Miranda, IM | 1 |
| Almeida-Coelho, J | 1 |
| Vasques-Nóvoa, F | 1 |
| Carvalho, D | 1 |
| Lourenço, A | 1 |
| Falcão-Pires, I | 1 |
| Leite-Moreira, A | 1 |
| Yang, L | 1 |
| Sun, X | 1 |
| Tao, H | 1 |
| Zhao, Y | 1 |
| Kumar, S | 1 |
| Dayal, D | 1 |
| Attri, S | 1 |
| Gupta, A | 1 |
| Bhalla, A | 1 |
| Xia, B | 1 |
| Shi, XC | 1 |
| Xie, BC | 1 |
| Zhu, MQ | 1 |
| Chu, XY | 1 |
| Cai, GH | 1 |
| Liu, M | 1 |
| Yang, SZ | 1 |
| Mitchell, GA | 1 |
| Pang, WJ | 1 |
| Wu, JW | 1 |
| Nie, X | 1 |
| Xu, Y | 1 |
| Ma, X | 1 |
| Xiao, Y | 1 |
| Bao, Y | 1 |
| Yang, S | 1 |
| Ye, S | 1 |
| Zupo, R | 1 |
| Castellana, F | 1 |
| Sardone, R | 1 |
| Lampignano, L | 1 |
| Paradiso, S | 1 |
| Giagulli, VA | 1 |
| Triggiani, V | 1 |
| Di Lorenzo, L | 1 |
| Giannelli, G | 1 |
| De Pergola, G | 4 |
| Fontenelle, LC | 1 |
| Feitosa, MM | 1 |
| Freitas, TEC | 1 |
| Severo, JS | 1 |
| Morais, JBS | 1 |
| Henriques, GS | 1 |
| Oliveira, FE | 1 |
| Moita Neto, JM | 1 |
| Marreiro, DDN | 1 |
| Fu, J | 1 |
| An, Y | 1 |
| Duan, Y | 1 |
| Wang, G | 2 |
| Tabachnik, T | 1 |
| Kisliouk, T | 1 |
| Marco, A | 1 |
| Meiri, N | 1 |
| Weller, A | 1 |
| Wang, X | 3 |
| Chen, J | 1 |
| Zhu, CL | 1 |
| Gao, J | 1 |
| Rampersad, S | 1 |
| Bu, L | 1 |
| Qu, S | 1 |
| Xia, SF | 1 |
| Duan, XM | 1 |
| Cheng, XR | 1 |
| Chen, LM | 1 |
| Kang, YJ | 1 |
| Wang, P | 1 |
| Tang, X | 1 |
| Shi, YH | 1 |
| Le, GW | 1 |
| Matesanz, N | 1 |
| Bernardo, E | 1 |
| Acín-Pérez, R | 1 |
| Manieri, E | 1 |
| Pérez-Sieira, S | 1 |
| Hernández-Cosido, L | 1 |
| Montalvo-Romeral, V | 1 |
| Mora, A | 1 |
| Rodríguez, E | 1 |
| Leiva-Vega, L | 1 |
| Lechuga-Vieco, AV | 1 |
| Ruiz-Cabello, J | 1 |
| Torres, JL | 1 |
| Crespo-Ruiz, M | 1 |
| Centeno, F | 1 |
| Álvarez, CV | 1 |
| Marcos, M | 1 |
| Enríquez, JA | 1 |
| Nogueiras, R | 1 |
| Sabio, G | 1 |
| Katz, LS | 1 |
| Xu, S | 1 |
| Ge, K | 1 |
| Scott, DK | 1 |
| Gershengorn, MC | 1 |
| Ahmadi, S | 2 |
| Eshraghian, MR | 2 |
| Hedayati, M | 2 |
| Pishva, H | 2 |
| Panveloski-Costa, AC | 1 |
| Serrano-Nascimento, C | 1 |
| Bargi-Souza, P | 1 |
| Poyares, LL | 1 |
| Viana, GS | 1 |
| Nunes, MT | 2 |
| You, L | 1 |
| Cui, X | 1 |
| Li, Y | 2 |
| Xu, P | 1 |
| Zhu, L | 1 |
| Wen, J | 1 |
| Pang, L | 1 |
| Guo, X | 1 |
| Ji, C | 1 |
| Çatli, G | 1 |
| Fujisawa, H | 1 |
| Kirbiyik, Ö | 1 |
| Mimoto, MS | 1 |
| Gençpinar, P | 1 |
| Özdemir, TR | 1 |
| Dündar, BN | 1 |
| Dumitrescu, AM | 1 |
| Ortega-Olvera, C | 1 |
| Ulloa-Aguirre, A | 1 |
| Ángeles-Llerenas, A | 1 |
| Mainero-Ratchelous, FE | 1 |
| González-Acevedo, CE | 1 |
| Hernández-Blanco, ML | 1 |
| Ziv, E | 1 |
| Avilés-Santa, L | 1 |
| Pérez-Rodríguez, E | 1 |
| Torres-Mejía, G | 1 |
| Reyes-Garcia, JG | 1 |
| Rodríguez-Flores, M | 1 |
| Kaufer-Horwitz, M | 1 |
| García-García, E | 1 |
| Patel, VJ | 1 |
| Joharapurkar, AA | 1 |
| Kshirsagar, SG | 1 |
| Sutariya, BK | 1 |
| Patel, MS | 1 |
| Bahekar, RH | 1 |
| Jain, MR | 1 |
| De Sibio, MT | 2 |
| Luvizotto, RA | 3 |
| Olimpio, RM | 3 |
| Corrêa, CR | 1 |
| Marino, J | 1 |
| Conde, SJ | 3 |
| Ferreira, AL | 1 |
| Padovani, CR | 3 |
| Roelfsema, F | 1 |
| Veldhuis, JD | 1 |
| Aypak, C | 1 |
| Türedi, O | 1 |
| Yüce, A | 1 |
| Görpelioğlu, S | 1 |
| Agnihothri, RV | 1 |
| Courville, AB | 1 |
| Linderman, JD | 1 |
| Smith, S | 1 |
| Brychta, R | 1 |
| Remaley, A | 1 |
| Chen, KY | 1 |
| Simchowitz, L | 1 |
| Celi, FS | 1 |
| Ren, R | 1 |
| Jiang, X | 1 |
| Zhang, X | 1 |
| Guan, Q | 1 |
| Yu, C | 1 |
| Gao, L | 1 |
| Zhang, H | 1 |
| Zhao, J | 2 |
| Torun, E | 1 |
| Özgen, IT | 1 |
| Gökçe, S | 1 |
| Aydın, S | 1 |
| Cesur, Y | 1 |
| Liu, X | 1 |
| Wang, S | 1 |
| You, Y | 1 |
| Meng, M | 1 |
| Zheng, Z | 1 |
| Dong, M | 1 |
| Lin, J | 1 |
| Zhao, Q | 1 |
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| Yuan, X | 1 |
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| Huang, Y | 1 |
| Wang, D | 1 |
| Zhan, J | 1 |
| Jong Lee, H | 1 |
| Speakman, JR | 1 |
| Jin, W | 1 |
| Kelderman-Bolk, N | 1 |
| Visser, TJ | 3 |
| Tijssen, JP | 1 |
| Berghout, A | 1 |
| Herter-Aeberli, I | 1 |
| Cherkaoui, M | 1 |
| El Ansari, N | 1 |
| Rohner, R | 1 |
| Stinca, S | 1 |
| Chabaa, L | 1 |
| von Eckardstein, A | 1 |
| Aboussad, A | 1 |
| Zimmermann, MB | 2 |
| Fonseca, TL | 1 |
| Fernandes, GW | 1 |
| McAninch, EA | 1 |
| Bocco, BM | 1 |
| Abdalla, SM | 1 |
| Ribeiro, MO | 5 |
| Mohácsik, P | 1 |
| Fekete, C | 1 |
| Li, D | 1 |
| Xing, X | 1 |
| Wang, T | 1 |
| Gereben, B | 1 |
| Bianco, AC | 4 |
| Kahr, MK | 1 |
| Antony, KM | 1 |
| DelBeccaro, M | 1 |
| Hu, M | 1 |
| Aagaard, KM | 1 |
| Suter, MA | 1 |
| Knight, BA | 1 |
| Shields, BM | 1 |
| Hattersley, AT | 1 |
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| Tarakcioglu, M | 1 |
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| Tagami, T | 1 |
| Yamakage, H | 1 |
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| Satoh-Asahara, N | 1 |
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| Türker, BÇ | 1 |
| Çetin, F | 1 |
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| Liu, P | 1 |
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| Healy, ME | 1 |
| Weber, A | 2 |
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| Jall, S | 1 |
| Brandt, S | 1 |
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| Schramm, KW | 1 |
| Biebermann, H | 1 |
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| Liu, F | 1 |
| Köhrle, J | 1 |
| Rozman, J | 1 |
| Fuchs, H | 1 |
| Gailus-Durner, V | 1 |
| Hrabě de Angelis, M | 1 |
| Hofmann, SM | 1 |
| Yang, B | 1 |
| Tschöp, MH | 1 |
| DiMarchi, R | 1 |
| Müller, TD | 1 |
| da Silva Teixeira, S | 1 |
| Filgueira, C | 1 |
| Sieglaff, DH | 1 |
| Benod, C | 1 |
| Villagomez, R | 1 |
| Minze, LJ | 1 |
| Zhang, A | 1 |
| Webb, P | 1 |
| Askari, A | 1 |
| Ehrampoush, E | 1 |
| Homayounfar, R | 1 |
| Bahramali, E | 1 |
| Farjam, M | 1 |
| Shu, L | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Activating Brown Adipose Tissue Through Exercise: Randomized Controlled Trial[NCT02365129] | 180 participants (Anticipated) | Interventional | 2015-02-28 | Recruiting | |||
| Estudo Longitudinal de Saúde do Adulto[NCT02320461] | 15,105 participants (Actual) | Observational | 2008-08-31 | Active, not recruiting | |||
| Effect of Body Composition on Thyroid Hormone Levels Among Overweight and Obese Subjects[NCT04327375] | 250 participants (Actual) | Observational | 2019-01-01 | Completed | |||
| Effects of GLP-1 Receptor Agonist on Fat Redistribution and Inflammatory Status in Female Patients With Type 2 Diabetes and Obesity[NCT02118376] | 20 participants (Anticipated) | Interventional | 2014-08-31 | Not yet recruiting | |||
| Gene Expression and Release of Inflammatory Mediators in Overweight Subjects Before and After Weight Loss[NCT00344266] | 144 participants (Actual) | Observational | 2006-06-19 | Completed | |||
| Assessment of the Improvement of the Cardiovascular Risk Profile in Obese Women After Correction of Iodine Deficiency[NCT01985204] | 162 participants (Actual) | Interventional | 2013-11-30 | Completed | |||
| ThyrOp: Individual Subclinical Hypothyroidism After Hemithyroidectomy for Benign Nontoxic Goiter - Focus on Weight Gain and Mitochondrial Dysfunction[NCT01358136] | 30 participants (Anticipated) | Observational | 2011-05-31 | Recruiting | |||
| A Phase 2A, Double-blind, Placebo-controlled, Randomized Study to Evaluate the Safety and Efficacy of TRC150094 in Increasing Insulin Sensitivity in Male Patients With Increased Cardiometabolic Risk[NCT01408667] | Phase 1/Phase 2 | 40 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| "Evaluation of the Intervention Program Obeldicks for Obese Children and Adolescents"[NCT00435734] | 4,000 participants (Actual) | Observational | 1999-07-31 | Active, not recruiting | |||
| The Effect of Bariatric Surgery on Thyroid Function and Morphology, a Retrospective Study[NCT00871130] | 300 participants (Actual) | Observational | 1998-01-31 | Completed | |||
| Improvement in Hypothalamic-Pituitary-Adrenal Axis Function After Continuous Positive Airway Pressure Therapy in Obstructive Sleep Apnea Syndrome[NCT00435643] | 45 participants (Actual) | Interventional | 2004-10-31 | Completed | |||
| Leptin in Human Energy and Neuroendocrine Homeostasis[NCT00265980] | 22 participants (Actual) | Interventional | 2002-07-31 | Terminated (stopped due to Closed by sponsor. Lack of funding.) | |||
| Association of Serum Fibroblast Growth Factor 21 (FGF-21) Levels With Resting Metabolic Rate (RMR), in Children and Adolescents With Hashimoto's Thyroiditis.[NCT02725879] | 60 participants (Anticipated) | Observational | 2016-03-31 | Recruiting | |||
| A Defined, Plant-based, 4-week Dietary Intervention Reduces Lp(a) and Other Atherogenic Particles[NCT03172611] | 33 participants (Actual) | Interventional | 2017-01-03 | Completed | |||
| Predicting Adaptive Thermogenesis[NCT00687115] | Phase 2 | 83 participants (Actual) | Interventional | 2008-09-18 | Completed | ||
| Changes in Anthropometric, Biochemical and DNA Damage Parameters After 3-weeks-567-kcal VLCD in Severely Obese Patients With BMI ≥ 35kg/m2[NCT05007171] | 22 participants (Actual) | Interventional | 2019-06-14 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
To measure the total energy expenditure/fat-free mass (FFM) (in kcal/kg). (NCT00265980)
Timeframe: Baseline, 11 weeks, 18 weeks
| Intervention | kcal/kg (Mean) | ||
|---|---|---|---|
| Weight initial | Weight -10% placebo | Weight -10% leptin | |
| Leptin Depletion Study Participants (Total) | 51.1 | 41.7 | 48.1 |
To measure the metabolic changes associated with maintenance of a reduced body weight (in kcal/day) (NCT00265980)
Timeframe: Baseline, 11 weeks, 18 weeks
| Intervention | kcal/day (Mean) | ||
|---|---|---|---|
| Weight initial | Weight -10% placebo | Weight -10% leptin | |
| Leptin Depletion Study Participants (Total) | 3131 | 2457 | 2766 |
19 reviews available for triiodothyronine and Obesity
| Article | Year |
|---|---|
Thyrotropin secretion patterns in health and disease.
Topics: Adult; Animals; Circadian Rhythm; Female; Health Status; Humans; Hypothalamo-Hypophyseal System; Hyp | 2013 |
Subclinical hypothyroidism in childhood - current knowledge and open issues.
Topics: Anticonvulsants; Antiviral Agents; Asymptomatic Diseases; Atherosclerosis; Bone Diseases, Metabolic; | 2016 |
Obesity and thyroid function.
Topics: Adipokines; Animals; Anorexia Nervosa; Body Weight; Energy Metabolism; Humans; Leptin; Obesity; Thyr | 2010 |
Thyroid hormone therapy for obesity and nonthyroidal illnesses: a systematic review.
Topics: Adult; Aged; Anti-Obesity Agents; Basal Metabolism; Caloric Restriction; Female; Heart Rate; Humans; | 2009 |
Thyroid axis alterations in childhood obesity.
Topics: Adipose Tissue; Child; Humans; Hypothyroidism; Leptin; Obesity; Risk Reduction Behavior; Thyrotropin | 2012 |
Energy balance and pollution by organochlorines and polychlorinated biphenyls.
Topics: Adipose Tissue; Animals; Body Composition; Energy Metabolism; Environmental Pollutants; Humans; Inse | 2003 |
Classical endocrine diseases causing obesity.
Topics: Catecholamines; Cushing Syndrome; Endocrine System Diseases; Female; Glucocorticoids; Humans; Hypoth | 2008 |
Thyroid hormone as a determinant of energy expenditure and the basal metabolic rate.
Topics: Animals; Basal Metabolism; Bile Acids and Salts; Energy Metabolism; Humans; Iodide Peroxidase; Iodot | 2008 |
Effects of thyroid hormone analogs on lipid metabolism and thermogenesis.
Topics: Animals; Antimetabolites; Brain; Energy Metabolism; Humans; Hydantoins; Lipid Metabolism; Lipid Meta | 2008 |
Human uncoupling proteins and obesity.
Topics: Adenosine Triphosphate; Adipose Tissue, Brown; Adrenergic beta-Agonists; Animals; Base Sequence; Car | 1999 |
Thyroid hormone metabolism in obesity.
Topics: Energy Intake; Humans; Obesity; Thyroid Hormones; Thyrotropin; Thyrotropin-Releasing Hormone; Thyrox | 2000 |
Thyroid hormones and treatment of obesity.
Topics: Body Temperature Regulation; Humans; Obesity; Thyroid Hormones; Triiodothyronine; Weight Loss | 2000 |
[Cell receptor defects as the cause of endocrine and metabolic diseases (author's transl)].
Topics: Adult; Binding Sites; Cell Membrane; Child; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type | 1979 |
[Alternation of thyroidal function by overeating and starvation (author's transl)].
Topics: Feeding Behavior; Humans; Obesity; Starvation; Thyroid Gland; Triiodothyronine | 1979 |
Pharmacological approaches to treating the obese patient.
Topics: Amphetamines; Appetite Depressants; Body Weight; Cardiovascular System; Central Nervous System; Chor | 1976 |
Brown adipose tissue thermogenesis and obesity.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Carbohydrate Metabolism; Diet; Glucagon | 1989 |
Regulation of energy balance.
Topics: Adipose Tissue, Brown; Aging; Animals; Basal Metabolism; Body Constitution; Body Temperature Regulat | 1985 |
The treatment of obesity.
Topics: Amphetamine; Behavior Therapy; Chorionic Gonadotropin; Dextroamphetamine; Exercise Therapy; Hospital | 1972 |
The management of obesity: some recent concepts.
Topics: Adaptation, Psychological; Adipose Tissue; Appetite Depressants; Attitude; Chlorphentermine; Defense | 1969 |
43 trials available for triiodothyronine and Obesity
| Article | Year |
|---|---|
Higher Muscle Mass Implies Increased Free-Thyroxine to Free-Triiodothyronine Ratio in Subjects With Overweight and Obesity.
Topics: Adult; Anthropometry; Biomarkers; Body Mass Index; Electric Impedance; Female; Humans; Male; Middle | 2020 |
New association of bone morphogenetic protein 4 concentrations with fat distribution in obesity and Exenatide intervention on it.
Topics: Absorptiometry, Photon; Adiposity; Adult; Body Mass Index; Bone Morphogenetic Protein 4; China; Chol | 2017 |
Moderate weight loss is sufficient to affect thyroid hormone homeostasis and inhibit its peripheral conversion.
Topics: Adipose Tissue; Adult; Body Mass Index; Energy Metabolism; Female; Homeostasis; Humans; Male; Obesit | 2014 |
Quality of life in patients with primary hypothyroidism related to BMI.
Topics: Adult; Anxiety; Autoantibodies; Autoantigens; Body Mass Index; Depression; Female; Hormone Replaceme | 2015 |
Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial.
Topics: Administration, Oral; Adult; Blood Glucose; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Die | 2015 |
Contribution of individual organ mass loss to weight loss-associated decline in resting energy expenditure.
Topics: Adipose Tissue; Adult; Body Fluid Compartments; Diet, Reducing; Energy Metabolism; Female; Humans; M | 2009 |
Changes in lifestyle improve body composition, thyroid function, and structure in obese children.
Topics: Adolescent; Autoantibodies; Body Composition; Child; Female; Humans; Life Style; Male; Obesity; Over | 2012 |
Thyroid function tests in obese prepubertal children: correlations with insulin sensitivity and body fat distribution.
Topics: Adiponectin; Adiposity; Blood Glucose; C-Peptide; Child; Female; Humans; Insulin; Insulin Resistance | 2012 |
TSH and free triiodothyronine concentrations are associated with weight loss in a lifestyle intervention and weight regain afterwards in obese children.
Topics: Adolescent; Body Mass Index; Child; Child Development; Diet, Reducing; Exercise; Female; Follow-Up S | 2013 |
The effect of vitamin A supplementation on thyroid function in premenopausal women.
Topics: Adolescent; Adult; Body Mass Index; Dietary Supplements; Double-Blind Method; Down-Regulation; Femal | 2012 |
Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy.
Topics: Aged; Body Weight; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agen | 2007 |
A controlled study of thyroid analogs in the therapy of obesity.
Topics: Adolescent; Adult; Humans; Obesity; Placebos; Thyroxine; Triiodothyronine | 1967 |
Treatment of obesity with triiodothyronine and a very-low-calorie liquid formula diet.
Topics: Basal Metabolism; Clinical Trials as Topic; Diet; Diet, Reducing; Energy Intake; Female; Humans; Mal | 1980 |
Obesity treated with triiodothyronine and low calorie liquid diet.
Topics: Body Weight; Clinical Trials as Topic; Diet, Reducing; Energy Intake; Hormones; Humans; Obesity; Tim | 1980 |
Obesity treated with triiodothyronine and low calorie liquid diet.
Topics: Animals; Basal Metabolism; Body Weight; Clinical Trials as Topic; Hormones; Humans; Obesity; Placebo | 1980 |
The effect of beta-adrenergic blockade on metabolic rate and peripheral thyroid metabolism in obesity.
Topics: Adrenergic beta-Antagonists; Adult; Basal Metabolism; Catecholamines; Diet, Reducing; Female; Humans | 1980 |
Metabolic responses in grossly obese subjects treated with a very-low-calorie diet with and without triiodothyronine treatment.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Body Weight; Diet; Energy Intake; Female; Humans; Hydro | 1983 |
Variability in body protein loss during protracted, severe caloric restriction: role of triiodothyronine and other possible determinants.
Topics: Adaptation, Physiological; Adult; Basal Metabolism; Body Composition; Body Weight; Diet, Reducing; D | 1984 |
The effect of a low-calorie diet alone and in combination with triiodothyronine therapy on weight loss and hypophyseal thyroid function in obesity.
Topics: Adult; Body Weight; Diet; Energy Intake; Female; Humans; Male; Obesity; Pituitary Gland, Anterior; T | 1983 |
Effect of 'physiological' doses of triiodothyronine replacement on the hormonal and metabolic adaptation to short-term semistarvation and to low-calorie diet in obese patients.
Topics: Adult; Combined Modality Therapy; Dietary Carbohydrates; Dietary Proteins; Energy Intake; Female; Hu | 1984 |
Serum levels of T4, T3, reverse T3, 3,3'-diiodothyronine and 3',5'-diiodothyronine in obesity, before and after jejuno-ileal bypass.
Topics: Adult; Diiodothyronines; Female; Humans; Ileum; Jejunum; Male; Middle Aged; Obesity; Thyronines; Thy | 1981 |
The effect of obesity and drastic caloric restriction on serum prolactin and thyroid stimulating hormone.
Topics: Adolescent; Adult; Diet, Reducing; Female; Humans; Male; Middle Aged; Nitrogen; Obesity; Prolactin; | 1981 |
Long-term evaluation of thyroidal response to partial calorie restriction in obesity.
Topics: Adult; Body Weight; Diet, Reducing; Female; Humans; Male; Middle Aged; Obesity; Thyroid Hormones; Th | 1981 |
Iodothyronines and thyrotrophin in serum after jejunoileostomy with 3:1 or 1:3 jejunoileal ratio.
Topics: Adult; Female; Humans; Ileum; Jejunum; Male; Obesity; Thyrotropin; Thyroxine; Time Factors; Triiodot | 1981 |
Growth hormone administration in addition to a very low calorie diet and an exercise program in obese subjects.
Topics: Adult; Blood Glucose; Carrier Proteins; Diet, Reducing; Double-Blind Method; Energy Intake; Epinephr | 1995 |
Fluoxetine increases resting energy expenditure and basal body temperature in humans.
Topics: Adult; Body Temperature; Chemotherapy, Adjuvant; Diet, Reducing; Double-Blind Method; Energy Metabol | 1995 |
Insulin sensitivity and lipid levels in obese subjects after slimming diets with different complex and simple carbohydrate content.
Topics: Adult; Blood Glucose; Diet, Reducing; Dietary Carbohydrates; Dietary Fiber; Glucose Clamp Technique; | 1993 |
Continuous subcutaneous infusion of low dose growth hormone decreases serum sex-hormone binding globulin and testosterone concentrations in moderately obese middle-aged men.
Topics: Adult; Drug Administration Schedule; Growth Hormone; Humans; Infusion Pumps; Injections, Subcutaneou | 1996 |
Phosphate supplementation prevents a decrease of triiodothyronine and increases resting metabolic rate during low energy diet.
Topics: Adult; Body Weight; Diet, Reducing; Double-Blind Method; Energy Intake; Energy Metabolism; Female; H | 1996 |
The effect of dehydroepiandrosterone combined with a low-fat diet in spontaneously obese dogs: a clinical trial.
Topics: Animals; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dehydroepiandrosterone; Diet, Fat-Restrict | 1998 |
Discrepancy between serum leptin values and total body fat in response to the oral growth hormone secretagogue MK-677.
Topics: Administration, Oral; Adult; Body Composition; Cholagogues and Choleretics; Double-Blind Method; Dru | 1999 |
A low serum leptin level at baseline and a large early decline in leptin predict a large 1-year weight reduction in energy-restricted obese humans.
Topics: Adolescent; Adult; Body Mass Index; Diet, Reducing; Energy Intake; Female; Humans; Hydrocortisone; I | 1999 |
Effect of catecholamine replacement with levodopa on the metabolic response to semistarvation.
Topics: Adaptation, Physiological; Adult; Basal Metabolism; Diet, Reducing; Energy Metabolism; Female; Human | 1979 |
Effect of fenfluramine on serum T3, T4 and TSH levels in obesity.
Topics: Adult; Case-Control Studies; Diet, Reducing; Female; Fenfluramine; Humans; Obesity; Prospective Stud | 1992 |
Calorie restriction and iopanoic acid effects on thyroid hormone metabolism.
Topics: Adult; Diet, Reducing; Double-Blind Method; Energy Intake; Humans; Iopanoic Acid; Kinetics; Male; Ob | 1990 |
Effects of a 'physiological' dose of triiodothyronine on obese subjects during a protein-sparing diet.
Topics: Adult; Clinical Trials as Topic; Diet, Reducing; Dietary Proteins; Female; Humans; Nitrogen; Obesity | 1986 |
Changes in bone and muscle constituents during dieting for obesity.
Topics: Adolescent; Adult; Bone and Bones; Calcium; Diet, Reducing; Dietary Carbohydrates; Female; Humans; H | 1986 |
[Influence of low-caloric-diet and d-triiodothyronine on serum lipids and body weight (author's transl)].
Topics: Body Weight; Cholesterol; Diet, Reducing; Humans; Lipids; Obesity; Placebos; Triiodothyronine | 1974 |
Effect of triiodothyronine on some metabolic responses of obese patients.
Topics: Adolescent; Adult; Blood Pressure; Body Height; Body Weight; Clinical Trials as Topic; Creatinine; D | 1973 |
Triiodothyronine and placebo in the treatment of obesity. A study of fifty-five patients.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Obesity; Placebos; Triiodothyron | 1969 |
Quantitative and qualitative effects of L-triiodothyronine in massive obesity.
Topics: Adipose Tissue; Adult; Aged; Buttocks; Chromatography, Gas; Clinical Trials as Topic; Diet, Reducing | 1970 |
Effects of triiodothyronine, growth hormone and anabolic steroids on nitrogen excretion and oxygen consumption of obese patients.
Topics: Adult; Body Weight; Clinical Trials as Topic; Female; Growth Hormone; Humans; Methandrostenolone; Mi | 1971 |
Triiodothyronine and mercurial diuretics. Effects on excretion of a water load and on plasma free fatty acids in obese patients.
Topics: Adult; Diet; Epinephrine; Fatty Acids, Nonesterified; Female; Humans; Obesity; Organomercury Compoun | 1969 |
401 other studies available for triiodothyronine and Obesity
| Article | Year |
|---|---|
Association of serum proprotein convertase Subtilisin/Kexin Type 9 (PCSK9) level with thyroid function disorders.
Topics: Adolescent; Adult; Aged; Autoantibodies; Cross-Sectional Studies; Female; Humans; Hyperthyroidism; H | 2021 |
Independent associations of thyroid-related hormones with hepatic steatosis and insulin resistance in euthyroid overweight/obese Chinese adults.
Topics: Adult; China; Cross-Sectional Studies; Fatty Liver; Humans; Insulin Resistance; Obesity; Overweight; | 2021 |
Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance.
Topics: Adipocytes, Brown; Adipogenesis; Adipose Tissue, Brown; Animals; Cell Differentiation; Diet, Western | 2021 |
Circulating concentrations of free triiodothyronine are associated with central adiposity and cardiometabolic risk factors in young euthyroid adults.
Topics: Adiposity; Body Mass Index; Cardiometabolic Risk Factors; Cross-Sectional Studies; Fatty Liver; Fema | 2022 |
Thyroid-Stimulating Hormone and Thyroid Hormones and Incidence of Diabetes: Prospective Results of the Brazilian Longitudinal Study of Adult Health (ELSA-BRASIL).
Topics: Adult; Aged; Brazil; Cohort Studies; Diabetes Mellitus; Female; Humans; Incidence; Longitudinal Stud | 2022 |
Possible added value of thyroglobulin antibody (TgAb) testing in the evaluation of thyroidal status of subjects with overweight or obesity.
Topics: Adult; Autoantibodies; Humans; Hyperthyroidism; Hypothyroidism; Iodide Peroxidase; Iodine Radioisoto | 2022 |
The interactive effects of pre-pregnancy body mass index, thyroid function, and blood lipid levels on the risk of gestational diabetes mellitus: a crossover analysis.
Topics: Body Mass Index; Case-Control Studies; Diabetes, Gestational; Female; Humans; Lipids; Obesity; Pregn | 2022 |
Circulating free triiodothyronine concentration is positively associated with β-cell function in euthyroid patients with obesity and type 2 diabetes.
Topics: C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; Obesity; Thyroid Function Tes | 2022 |
Exploring associations of anthropometric parameters and serum triglycerides with serum thyroid hormones in young women.
Topics: Female; Humans; Obesity; Thinness; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; | 2022 |
Central and peripheral sensitivity to thyroid hormones and glucose metabolism in prepubertal children with obesity: pilot multicenter evaluation.
Topics: Child; Glucose; Humans; Insulin Resistance; Obesity; Overweight; Thyroid Hormone Resistance Syndrome | 2023 |
Central and peripheral sensitivity to thyroid hormones and glucose metabolism in prepubertal children with obesity: pilot multicenter evaluation.
Topics: Child; Glucose; Humans; Insulin Resistance; Obesity; Overweight; Thyroid Hormone Resistance Syndrome | 2023 |
Central and peripheral sensitivity to thyroid hormones and glucose metabolism in prepubertal children with obesity: pilot multicenter evaluation.
Topics: Child; Glucose; Humans; Insulin Resistance; Obesity; Overweight; Thyroid Hormone Resistance Syndrome | 2023 |
Central and peripheral sensitivity to thyroid hormones and glucose metabolism in prepubertal children with obesity: pilot multicenter evaluation.
Topics: Child; Glucose; Humans; Insulin Resistance; Obesity; Overweight; Thyroid Hormone Resistance Syndrome | 2023 |
The association between thyroid hormones and MAFLD is mediated by obesity and metabolic disorders and varies among MAFLD subtypes.
Topics: Humans; Metabolic Diseases; Non-alcoholic Fatty Liver Disease; Obesity; Overweight; Thyroid Hormones | 2023 |
Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Atherosclerosis; Drug-Related Side Effects an | 2022 |
RNA-seq reveals that anti-obesity irisin and triiodothyronine (T3) hormones differentially affect the purinergic signaling transcriptomics in differentiated human adipocytes.
Topics: Adipocytes; Fibronectins; Humans; Obesity; RNA-Seq; Transcriptome; Triiodothyronine | 2023 |
Effect of obesity and hypothyroidism on hepcidin concentration in pregnancy - a pilot study using maternal and umbilical cord blood at delivery day.
Topics: Female; Fetal Blood; Humans; Hypothyroidism; Iron; Obesity; Pilot Projects; Placenta; Pregnancy; Tri | 2022 |
Effects of Triiodothyronine Treatment in an Animal Model of Heart Failure with Preserved Ejection Fraction.
Topics: Animals; Calcium; Disease Models, Animal; Heart Failure; Obesity; Rats; Stroke Volume; Triiodothyron | 2023 |
The association between thyroid homeostasis parameters and obesity in subjects with euthyroidism.
Topics: Adult; Aged; Aged, 80 and over; Homeostasis; Humans; Middle Aged; Obesity; Retrospective Studies; Th | 2023 |
Levothyroxine supplementation for obesity-associated thyroid dysfunction in children: a prospective, randomized, case control study.
Topics: Case-Control Studies; Child; Female; Humans; Male; Obesity; Prospective Studies; Random Allocation; | 2019 |
Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice.
Topics: Adipocytes, Brown; Adipocytes, White; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Anti-Ob | 2020 |
Association between Abdominal Fat Distribution and Free Triiodothyronine in a Euthyroid Population.
Topics: Abdominal Fat; Adult; Aged; Aged, 80 and over; Female; Goiter, Nodular; Humans; Male; Middle Aged; O | 2020 |
Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Male; Middle Aged; Non-a | 2020 |
Selenium status and its relationship with thyroid hormones in obese women.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Humans; Middle Aged; Obesity; Selenium; Thyroid | 2021 |
Association Between Body Mass Index and Thyroid Function in Euthyroid Chinese Adults.
Topics: Adult; Asian People; Body Mass Index; Body Weight; China; Female; Humans; Male; Middle Aged; Obesity | 2021 |
Thyroid Hormone-Dependent Epigenetic Regulation of Melanocortin 4 Receptor Levels in Female Offspring of Obese Rats.
Topics: Animals; Body Weight; Eating; Epigenesis, Genetic; Female; Maternal Nutritional Physiological Phenom | 2017 |
Role of miR-383 and miR-146b in different propensities to obesity in male mice.
Topics: Animals; Diet, High-Fat; Energy Metabolism; Gene Expression Regulation; Hepatocytes; Liver; Male; Mi | 2017 |
MKK6 controls T3-mediated browning of white adipose tissue.
Topics: Adipocytes, White; Adipose Tissue, White; Adult; Aged; Animals; Case-Control Studies; Diabetes Melli | 2017 |
T3 and Glucose Coordinately Stimulate ChREBP-Mediated Ucp1 Expression in Brown Adipocytes From Male Mice.
Topics: Active Transport, Cell Nucleus; Adipocytes, Brown; Adipogenesis; Animals; Basic Helix-Loop-Helix Leu | 2018 |
Relationship between estrogen and body composition, energy, and endocrine factors in obese women with normal and low REE.
Topics: Adult; Body Composition; Eating; Energy Intake; Energy Metabolism; Estrogens; Female; Humans; Leptin | 2018 |
Beneficial effects of thyroid hormone on adipose inflammation and insulin sensitivity of obese Wistar rats.
Topics: Adipose Tissue; Animals; Blood Glucose; Cytokines; Feedback, Physiological; Insulin Resistance; Male | 2018 |
Evaluation and optimization of differentiation conditions for human primary brown adipocytes.
Topics: Adipocytes, Brown; Adipogenesis; Adipose Tissue, Brown; Cell Culture Techniques; Cell Differentiatio | 2018 |
A Novel Homozygous Selenocysteine Insertion Sequence Binding Protein 2 (SECISBP2, SBP2) Gene Mutation in a Turkish Boy.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Humans; Male; Muscle Weakness; Mutagenesis, In | 2018 |
Thyroid hormones and breast cancer association according to menopausal status and body mass index.
Topics: Adult; Body Mass Index; Breast Neoplasms; Case-Control Studies; Female; Humans; Incidence; Mexico; M | 2018 |
Safety of drug combinations based on psychoactive agents in the treatment of obesity (A reply by the authors).
Topics: Atropine; Diazepam; Drug Combinations; Emodin; Humans; Obesity; Phenylpropanolamine; Psychotropic Dr | 2019 |
Safety of drug combinations based on psychoactive agents in the treatment of obesity.
Topics: Atropine; Diazepam; Drug Combinations; Emodin; Humans; Obesity; Phenylpropanolamine; Psychotropic Dr | 2019 |
Activation of GLP-1 and Glucagon Receptors Regulates Bile Homeostasis Independent of Thyroid Hormone.
Topics: Animals; Bile; Diet, High-Fat; Glucagon-Like Peptide 1; Liver; Male; Methimazole; Mice; Mice, Inbred | 2019 |
UCP2, SHBG, Leptin, and T3 Levels are Associated with Resting Energy Expenditure in Obese Women.
Topics: Adult; Biomarkers; Energy Metabolism; Female; Humans; Leptin; Middle Aged; Obesity; Rest; Sex Hormon | 2020 |
A comparative genotoxicity study of a supraphysiological dose of triiodothyronine (T₃) in obese rats subjected to either calorie-restricted diet or hyperthyroidism.
Topics: Adipose Tissue; Animals; Body Composition; Body Weight; Caloric Restriction; Comet Assay; Energy Int | 2013 |
Thyroid-stimulating hormone (TSH) level in nutritionally obese children and metabolic co-morbidity.
Topics: Adolescent; Child; Child, Preschool; Comorbidity; Cross-Sectional Studies; Female; Humans; Lipids; M | 2013 |
Association between thyroid hormones and body fat in euthyroid subjects.
Topics: Adipose Tissue; Adult; Blood Glucose; Body Composition; Cross-Sectional Studies; Female; Humans; Ins | 2014 |
Thyroid hormone levels in obese children and adolescents with non-alcoholic fatty liver disease.
Topics: Adolescent; Anthropometry; Biomarkers; Case-Control Studies; Child; Fatty Liver; Female; Follow-Up S | 2014 |
Brown Adipose Tissue Transplantation Reverses Obesity in Ob/Ob Mice.
Topics: Adiponectin; Adipose Tissue; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Energy Metabolis | 2015 |
Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.
Topics: Analysis of Variance; Animals; Animals, Newborn; Calorimetry, Indirect; Diet, High-Fat; Disease Susc | 2015 |
Increasing maternal obesity is associated with alterations in both maternal and neonatal thyroid hormone levels.
Topics: Adult; Birth Weight; Body Mass Index; Female; Fetal Blood; Humans; Infant, Newborn; Linear Models; M | 2016 |
Maternal hypothyroxinaemia in pregnancy is associated with obesity and adverse maternal metabolic parameters.
Topics: Adult; Body Mass Index; Cholesterol, HDL; Female; Gestational Age; Glycated Hemoglobin; Humans; Hypo | 2016 |
Subcutaneous Adipose Tissue Type II Deiodinase Gene Expression Reduced in Obese Individuals with Metabolic Syndrome.
Topics: Adult; Blood Glucose; Body Mass Index; Cholesterol; Female; Gene Expression Regulation, Enzymologic; | 2016 |
Serum free thyroxine levels are associated with the efficacy of weight reduction therapy in obese female patients.
Topics: Academic Medical Centers; Body Mass Index; Cohort Studies; Cross-Sectional Studies; Female; Humans; | 2016 |
FT3/FT4 ratio predicts non-alcoholic fatty liver disease independent of metabolic parameters in patients with euthyroidism and hypothyroidism.
Topics: Adult; Biomarkers; Cholesterol; Female; Humans; Hypothyroidism; Insulin Resistance; Male; Metabolic | 2016 |
A disputed evidence on obesity: comparison of the effects of Rcan2(-/-) and Rps6kb1(-/-) mutations on growth and body weight in C57BL/6J mice.
Topics: Adipose Tissue; Animals; Animals, Newborn; Birth Weight; Body Composition; Body Size; Body Weight; E | 2016 |
Subclinical Hypothyroidism in Danish Lean and Obese Children and Adolescents.
Topics: Adolescent; Body Mass Index; Body Weight; Child; Cross-Sectional Studies; Denmark; Female; Humans; H | 2017 |
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
Topics: Animals; Atherosclerosis; Body Weight; Bone and Bones; Chemical Engineering; Cholesterol; Diabetes M | 2016 |
3,5-diiodothyronine (3,5-T2) reduces blood glucose independently of insulin sensitization in obese mice.
Topics: Animals; Blood Glucose; Diet, High-Fat; Diiodothyronines; Energy Metabolism; Hep G2 Cells; Humans; I | 2017 |
Serum insulin in pathogenesis and treatment of osteoarthritis.
Topics: Adipokines; Cartilage; Cell Differentiation; Cell Proliferation; Chondrocytes; Disease Progression; | 2017 |
A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes.
Topics: Adipocytes, Brown; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Cells, Cultured; Cytoplasm | 2017 |
Factitious thyrotoxicosis induced by mesotherapy: a case report.
Topics: Adipose Tissue; Adult; Cosmetic Techniques; Female; Humans; Obesity; Thyrotoxicosis; Triiodothyronin | 2008 |
Free T4 is negatively correlated with body mass index in euthyroid women.
Topics: Adult; Body Mass Index; Cholesterol; Cross-Sectional Studies; Female; Humans; Korea; Middle Aged; Ob | 2008 |
Thyroid function and structure are affected in childhood obesity.
Topics: Autoantibodies; Biopsy, Fine-Needle; Body Mass Index; Child; Cohort Studies; Cross-Sectional Studies | 2008 |
Effects of BDNF, T3, and corticosterone on expression of the hypothalamic obesity gene network in vivo and in vitro.
Topics: Age Factors; Animals; Body Composition; Brain-Derived Neurotrophic Factor; Cells, Cultured; Chick Em | 2009 |
Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats.
Topics: Age Factors; Aging; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Blotting, | 2009 |
A TRbeta-selective agonist confers resistance to diet-induced obesity.
Topics: Acetates; Adipose Tissue, Brown; Animals; Basal Metabolism; Benzhydryl Compounds; Cholesterol; Dieta | 2009 |
Weight loss through gastric banding: effects on TSH and thyroid hormones in obese subjects with normal thyroid function.
Topics: Adult; Bariatric Surgery; Case-Control Studies; Cholesterol; Cholesterol, HDL; Female; Humans; Insul | 2010 |
Administration of physiologic levels of triiodothyronine increases leptin expression in calorie-restricted obese rats, but does not influence weight loss.
Topics: Animals; Body Composition; Body Weight; Caloric Restriction; Energy Intake; Insulin; Leptin; Male; O | 2010 |
Association of serum TSH with high body mass differs between smokers and never-smokers.
Topics: Body Mass Index; Body Weight; Female; Humans; Hypothyroidism; Male; Norway; Obesity; Smoking; Thyroi | 2009 |
Expression and modulation of TUB by insulin and thyroid hormone in primary rat and murine 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adaptor Proteins, Signal Transducing; Adipocytes; Adipogenesis; Animals; Insulin; Male | 2009 |
Effects of experimental weight perturbation on skeletal muscle work efficiency, fuel utilization, and biochemistry in human subjects.
Topics: Adiponectin; Adult; Biopsy; Blood Glucose; Body Weight; Case-Control Studies; Energy Metabolism; Exe | 2010 |
Subclinical hypothyroidism affects mitochondrial function.
Topics: Adolescent; Adult; Anthropometry; Child; Citrate (si)-Synthase; Female; Humans; Hypothyroidism; Lipo | 2010 |
Thyroid function in obese children and adolescents.
Topics: Adolescent; Body Mass Index; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Life Style; | 2010 |
RARgamma and TRbeta expressions are decreased in PBMC and SWAT of obese subjects in weight gain.
Topics: Adult; Humans; Leukocytes, Mononuclear; Middle Aged; Obesity; Receptors, Retinoic Acid; Retinoic Aci | 2010 |
Impaired metabolic effects of a thyroid hormone receptor beta-selective agonist in a mouse model of diet-induced obesity.
Topics: Acetates; Adipocytes, Brown; Animals; Anti-Obesity Agents; Benzhydryl Compounds; Body Weight; Calori | 2010 |
TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet.
Topics: Adiposity; Animals; Blotting, Western; Body Weight; Carnitine O-Palmitoyltransferase; Dietary Fats; | 2010 |
Investigations of thyroid hormones and antibodies in obesity: leptin levels are associated with thyroid autoimmunity independent of bioanthropometric, hormonal, and weight-related determinants.
Topics: Adult; Analysis of Variance; Autoantibodies; Autoimmunity; Body Composition; Body Mass Index; Body W | 2010 |
Adipokine profile and insulin sensitivity in formerly obese women subjected to bariatric surgery or diet-induced long-term caloric restriction.
Topics: Adiponectin; Adult; Bariatric Surgery; Body Mass Index; Caloric Restriction; Case-Control Studies; C | 2010 |
Effects of trans-10,cis-12 CLA on liver size and fatty acid oxidation under energy restriction conditions in hamsters.
Topics: Acyl-CoA Oxidase; Animals; Caloric Restriction; Carnitine O-Palmitoyltransferase; Cricetinae; Dietar | 2011 |
Free triiodothyronine is associated with smoking habit, independently of obesity, body fat distribution, insulin, and metabolic parameters.
Topics: Adolescent; Adult; Aged; Body Composition; Body Fat Distribution; Body Mass Index; Cholesterol, HDL; | 2010 |
During rapid weight loss in obese children, reductions in TSH predict improvements in insulin sensitivity independent of changes in body weight or fat.
Topics: Adipose Tissue; Adolescent; Body Composition; Body Mass Index; Body Weight; Fasting; Female; Humans; | 2010 |
Maintenance of the thyroid axis during diet-induced obesity in rodents is controlled at the central level.
Topics: Analysis of Variance; Animals; Blotting, Western; Body Temperature; Diet; Energy Metabolism; Hypotha | 2010 |
Anthropomorphic thyroidopathies?
Topics: Adult; Body Mass Index; Carcinoma; Child, Preschool; Fasting; Humans; Hypothyroidism; Insulin; Lepti | 2010 |
Effects of long-term intraperitoneal injection of thyrotropin-releasing hormone (TRH) on aging- and obesity-related changes in body weight, lipid metabolism, and thyroid functions.
Topics: Aging; Animals; Body Weight; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Female; I | 2011 |
Impaired pharmacokinetics of levothyroxine in severely obese volunteers.
Topics: Adult; Area Under Curve; Autoantibodies; Body Mass Index; Body Weight; Case-Control Studies; Cohort | 2011 |
Arterial hypertension in obesity: relationships with hormone and anthropometric parameters.
Topics: Adult; Aldosterone; Biomarkers; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory | 2011 |
Thyroid hormone levels predict the change in body weight: a prospective study.
Topics: Adiponectin; Adult; Body Weight; Cohort Studies; Female; Follow-Up Studies; Humans; Insulin Resistan | 2011 |
Supraphysiological triiodothyronine doses diminish leptin and adiponectin gene expression, but do not alter resistin expression in calorie restricted obese rats.
Topics: Adiponectin; Adipose Tissue; Animals; Body Weight; Caloric Restriction; Dose-Response Relationship, | 2011 |
Pre- and post-weaning cold exposure does not lead to an obese phenotype in adult Brandt's voles (Lasiopodomys brandtii).
Topics: Agouti-Related Protein; Animals; Arvicolinae; Body Composition; Body Weight; Cold Temperature; Eatin | 2011 |
Association of metabolic syndrome parameters with TT3 and FT3/FT4 ratio in obese Turkish population.
Topics: Adolescent; Adult; Aged; Body Mass Index; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Obe | 2012 |
Prospectively measured thyroid hormones and thyroid peroxidase antibodies in relation to breast cancer risk.
Topics: Autoantibodies; Breast Neoplasms; Cell Proliferation; Female; Humans; Iodide Peroxidase; Middle Aged | 2012 |
Body fatness and markers of thyroid function among U.S. men and women.
Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Biomarkers; Body Mass Index; Female; Humans; Male; M | 2012 |
Experimental hyperthyroidism decreases gene expression and serum levels of adipokines in obesity.
Topics: Adiponectin; Adipose Tissue; Animals; Body Weight; Disease Models, Animal; Gene Expression Regulatio | 2012 |
Relation with HOMA-IR and thyroid hormones in obese Turkish women with metabolic syndrome.
Topics: Adult; Aged; Autoantibodies; Blood Pressure; Body Mass Index; Cholesterol; Cross-Sectional Studies; | 2012 |
Effects of living at two ambient temperatures on 24-h blood pressure and neuroendocrine function among obese and non-obese humans: a pilot study.
Topics: Adult; Blood Glucose; Blood Pressure; Catecholamines; Cholesterol; Ghrelin; Humans; Insulin; Japan; | 2013 |
Impact of body mass index on thyroid functions in Indian children.
Topics: Adolescent; Body Mass Index; Child; Child, Preschool; Female; Humans; Hypothyroidism; India; Male; O | 2013 |
Thyroid hormones before and after weight loss in obesity.
Topics: Adolescent; Body Mass Index; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Leptin; Mal | 2002 |
Triiodothyronine supplementation for hypothalamic obesity.
Topics: Adult; Brain Neoplasms; Child; Female; Humans; Hypothalamic Diseases; Male; Obesity; Treatment Outco | 2002 |
Greater than predicted decrease in energy expenditure during exercise after body weight loss in obese men.
Topics: Adult; Aged; Analysis of Variance; Body Composition; Energy Metabolism; Exercise; Female; Fenflurami | 2003 |
The effect of body weight and weight loss on thyroid volume and function in obese women.
Topics: Adipose Tissue; Adult; Body Composition; Body Constitution; Body Mass Index; Case-Control Studies; F | 2003 |
L-Triiodothyronine as adjunctive therapy in the management of obesity; preliminary report.
Topics: Combined Modality Therapy; Disease Management; Humans; Obesity; Triiodothyronine | 1957 |
[The influence of triiodothyronine on the water, salt, and nitrogen metabolism in obesity].
Topics: Humans; Leadership; Nitrogen; Obesity; Sodium Chloride; Sodium Chloride, Dietary; Triiodothyronine; | 1957 |
Liothyronine in the management of obesity.
Topics: Disease Management; Humans; Obesity; Triiodothyronine | 1959 |
Results of addition of liothyronine to a weight-reducing regimen.
Topics: Amobarbital; Amphetamine; Amphetamines; Humans; Obesity; Triiodothyronine | 1959 |
[Research on the process of water balance in obese patients under triiodothyronine therapy with special reference to aldosterone secretion in the urine and an antidiuretic principle in the serum (ADH)].
Topics: Aldosterone; Arginine Vasopressin; Humans; Obesity; Research; Triiodothyronine; Vasopressins; Water- | 1961 |
Water retention in obesity.
Topics: Heart Failure; Kidney Function Tests; Obesity; Triiodothyronine; Water-Electrolyte Balance | 1959 |
[The hormone effects of triiodothyroacetic acid studies in adipose and myxedematous patients].
Topics: Adiposity; Hormones; Humans; Myxedema; Obesity; Research; Triiodothyronine | 1959 |
DETERMINATION OF URINARY UNCONJUGAT- ED CORTISOL BY GLASS FIBER CHROMATOGRAPHY IN THE DIAGNOSIS OF CUSHING'S SYNDROME.
Topics: Adrenal Cortex Hormones; Blood Chemical Analysis; Carbon Isotopes; Chromatography; Creatine; Creatin | 1963 |
PHYSIOLOGY OF OBESITY.
Topics: Diet, Reducing; Fasting; Humans; Obesity; Physiology; Triiodothyronine | 1964 |
THYROID DIAGNOSTIC PROBLEMS.
Topics: Asthma; Deficiency Diseases; Female; Geriatrics; Goiter; Heart Diseases; Humans; Hyperthyroidism; Hy | 1964 |
[THERAPY OF OBESITY WITH THYROID HORMONES AND DIURETICS].
Topics: Diuretics; Humans; Obesity; Thyroid Hormones; Thyroxine; Triiodothyronine | 1964 |
THYROID FUNCTION IN PREGNANCY DETERMINED BY TRI 131 UPTAKE.
Topics: Abortion, Induced; Abortion, Spontaneous; Erythrocytes; Female; Humans; Infant; Infant Mortality; In | 1964 |
[L-TRIIODOTHYRONINE (TERTROXIN GLAXO) IN THE TREATMENT OF OBESITY].
Topics: Appetite Depressants; Obesity; Triiodothyronine | 1964 |
OBESITY: A PROBLEM WITH MANY FACETS: OBSERVATIONS ON TREATMENT WITH CHORIONIC GONADOTROPIN AS AN ADJUNCT TO DIETARY MEASURES.
Topics: Chorionic Gonadotropin; Diet; Diet, Reducing; Dietary Fats; Drug Therapy; Fatty Acids; Humans; Lipid | 1964 |
EFFECTS OF TRIIODOTHYRONINE AND THYROXIN ON THE LIPOLYTIC ACTION OF EPINEPHRINE IN MARKEDLY OBESE SUBJECTS.
Topics: Blood Chemical Analysis; Body Weight; Drug Therapy; Epinephrine; Fatty Acids; Geriatrics; Injections | 1965 |
THE EFFECT OF L-TRIIODOTHYRONINE ON THE FATTY ACID COMPOSITION OF HUMAN ADIPOSE TISSUE.
Topics: Adipose Tissue; Biomedical Research; Chromatography; Fatty Acids; Glycerides; Lipid Metabolism; Obes | 1965 |
[Thyroid hormones in the treatment of obesity].
Topics: Humans; Obesity; Thyroid Hormones; Triiodothyronine | 1962 |
Obese patients with obstructive sleep apnoea syndrome show a peculiar alteration of the corticotroph but not of the thyrotroph and lactotroph function.
Topics: Adrenocorticotropic Hormone; Adult; Area Under Curve; Case-Control Studies; Corticotropin-Releasing | 2004 |
The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction.
Topics: Animals; Blotting, Northern; Caloric Restriction; Constitutive Androstane Receptor; DNA, Complementa | 2004 |
Leptin, thyrotropin, and thyroid hormones in obese/overweight women before and after two levels of energy deficit.
Topics: Adipose Tissue; Body Composition; Body Mass Index; Diet, Reducing; Energy Intake; Energy Metabolism; | 2004 |
Effects of soybean isoflavones, probiotics, and their interactions on lipid metabolism and endocrine system in an animal model of obesity and diabetes.
Topics: Adipose Tissue; Animals; Body Composition; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, | 2004 |
Relationship of thyroid function with body mass index, leptin, insulin sensitivity and adiponectin in euthyroid obese women.
Topics: Adiponectin; Adult; Body Mass Index; Case-Control Studies; Female; Humans; Insulin Resistance; Inter | 2005 |
Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight.
Topics: Adult; Body Composition; Body Mass Index; Body Weight; Calorimetry; Diet, Reducing; Energy Intake; E | 2005 |
Altered brown adipose tissue and Na,K pump activities during diet-induced obesity and weight loss in rats.
Topics: Adenosine Triphosphatases; Adipose Tissue; Adipose Tissue, Brown; Animals; Body Composition; Body We | 1993 |
[To lose weight, let us make bile].
Topics: Adenosine Triphosphate; Adipocytes; Adipose Tissue, Brown; Animals; Bile; Bile Acids and Salts; Cycl | 2006 |
Hyperthyrotropinemia in obese children is reversible after weight loss and is not related to lipids.
Topics: Behavior Therapy; Child; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; E | 2006 |
Knocking down the diencephalic thyrotropin-releasing hormone precursor gene normalizes obesity-induced hypertension in the rat.
Topics: Animals; Blood Pressure; Body Weight; Hypertension; Leptin; Male; Metanephrine; Normetanephrine; Obe | 2007 |
Thyroid hormone receptor beta-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats.
Topics: Absorptiometry, Photon; Acetates; Adipose Tissue; Animals; Body Composition; Energy Metabolism; Fema | 2007 |
Impact of insulin sensitivity in relationship with prolactin and thyroid stimulating hormone.
Topics: Adult; Blood Glucose; Body Mass Index; Body Size; Cross-Sectional Studies; Fasting; Female; Humans; | 2007 |
Free triiodothyronine and thyroid stimulating hormone are directly associated with waist circumference, independently of insulin resistance, metabolic parameters and blood pressure in overweight and obese women.
Topics: Adipose Tissue; Adolescent; Adult; Aged; Blood Glucose; Blood Pressure; Body Composition; Body Tempe | 2007 |
Obesity increases free thyroxine proportionally to nonesterified fatty acid concentrations in adult neutered female cats.
Topics: Animals; Cats; Diabetes Mellitus, Type 2; Disease Progression; Fatty Acids, Nonesterified; Female; I | 2007 |
Triiodothyronine differentially regulates key metabolic factors in lean and obese cats.
Topics: Adipose Tissue; Animals; Cat Diseases; Cats; Fatty Acids, Nonesterified; Female; Gene Expression; Io | 2008 |
Case history: thyrotoxicosis factitia secondary to triiodothyronine acquired electronically from abroad.
Topics: Adult; Commerce; Humans; Internet; Obesity; Thyrotoxicosis; Triiodothyronine | 2007 |
Increase in depression symptoms with weight loss: association with glucose homeostasis and thyroid function.
Topics: Adult; Blood Glucose; Depression; Diet, Reducing; Glucose Tolerance Test; Homeostasis; Humans; Male; | 2008 |
Thyroid hormones and their relation to weight status.
Topics: Adolescent; Anorexia Nervosa; Body Weight; Female; Follow-Up Studies; Humans; Insulin; Insulin Resis | 2008 |
Ghrelin secretion is not reduced by increased fat mass during diet-induced obesity.
Topics: Adiposity; Animals; Dietary Fats; Disease Models, Animal; Fasting; Gastric Mucosa; Ghrelin; Homeosta | 2008 |
The effects of triiodothyronine on some metabolic parameters of obese individuals. Blood C-14-glucose replacement rate, respiratory C-14-O-2, the pentose cycle, the biological half-life of T-3 and the concentration of T-3 in adipose tissue.
Topics: Adult; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Humans; Male; Obesity; Pentoses; Respiration; | 1967 |
Physiological or adaptive alterations in the deiodination of thyroxine.
Topics: Acclimatization; Disease; Fasting; Female; Fetus; Humans; Infant, Newborn; Kinetics; Obesity; Pregna | 1984 |
Possible iatrogenic hypothyroidism.
Topics: Humans; Hypothyroidism; Iatrogenic Disease; Obesity; Thyroid Gland; Thyroid Hormones; Thyroxine; Tri | 1981 |
Nuclear triiodothyronine binding in mononuclear leukocytes in normal subjects and obese patients before and after fasting.
Topics: Adult; Alpha-Globulins; Cell Nucleus; Fasting; Female; Humans; Kinetics; Male; Monocytes; Obesity; R | 1982 |
[Effects of 3,5,3'-triiodothyroacetic acid (TRIAC) on protein metabolism of genetically obese or non-obese Zucker rats].
Topics: Animals; Brain; Carbon Radioisotopes; Female; Kidney; Leucine; Liver; Muscles; Myocardium; Obesity; | 1982 |
Solubilized nuclear thyroid hormone receptors in circulating human mononuclear cells.
Topics: Adult; Animals; Cell Nucleus; Chromatography, Gel; Fasting; Female; Humans; Hyperthyroidism; Hypothy | 1980 |
Thyroid hormone regulation of the catecholamine effects in human adipose tissue.
Topics: Adipose Tissue; Cyclic AMP; Humans; Hyperthyroidism; Isoproterenol; Lipolysis; Norepinephrine; Obesi | 1981 |
The role of T3 and its receptor in efficient metabolisers receiving very-low-calorie diets.
Topics: Diet, Reducing; Humans; Lymphocytes; Obesity; Receptors, Cell Surface; Receptors, Thyroid Hormone; T | 1981 |
[Urinary calcium and phosphate during fasting. Effect of various hormonal factors (author's transl)].
Topics: Adolescent; Adult; Aged; Calcitonin; Calcium; Fasting; Female; Humans; Male; Middle Aged; Obesity; P | 1982 |
[Obesity, energy expenditure and thyroid hormones].
Topics: Animals; Body Weight; Energy Intake; Energy Metabolism; Humans; Obesity; Physical Exertion; Rats; Re | 1982 |
Lymphocyte thyroid hormone receptors in obesity.
Topics: Adult; Female; Food, Formulated; Humans; Lymphocytes; Middle Aged; Obesity; Receptors, Cell Surface; | 1982 |
Relations between immunoreactive somatomedin C, insulin and T3 patterns during fasting in obese subjects.
Topics: Adolescent; Adult; Blood Glucose; Fasting; Female; Growth Hormone; Humans; Insulin; Insulin-Like Gro | 1984 |
Variations of thyroid hormones during total fasting in obese and in obese diabetic subjects.
Topics: Adult; Diabetes Mellitus; Fasting; Female; Humans; Insulin; Male; Middle Aged; Obesity; Thyroglobuli | 1984 |
[Role of excessive body weight and hormonal changes in the development of the main types of hyperlipoproteinemia].
Topics: Adrenocortical Hyperfunction; Adult; Growth Hormone; Humans; Hydrocortisone; Hyperinsulinism; Hyperl | 1984 |
Maximum calorie (sub-threshold) dieting of the obese and its hormonal response.
Topics: Adult; Body Weight; Diet, Reducing; Energy Intake; Energy Metabolism; Female; Humans; Obesity; Thyro | 1983 |
Thyroid function in altered nutritional state.
Topics: Adolescent; Adult; Anorexia Nervosa; Female; Humans; Male; Middle Aged; Nutrition Disorders; Obesity | 1983 |
New developments in medical therapy of obesity: thyroid and zinc.
Topics: Body Weight; Diet, Reducing; Hair; Humans; Hypothyroidism; Obesity; Thyroid (USP); Thyroid Hormones; | 1984 |
The effect of acute and chronic exercise on thyroid hormones in obesity.
Topics: Exercise Test; Exercise Therapy; Female; Humans; Middle Aged; Obesity; Physical Education and Traini | 1984 |
[Effect of thyroid hormones on noradrenaline-stimulated lipolysis in obesity].
Topics: Adolescent; Adult; Drug Therapy, Combination; Fatty Acids, Nonesterified; Female; Glycerol; Humans; | 1984 |
Role of counterregulatory hormones in the catabolic response to stress.
Topics: Adult; Amino Acids; Ammonia; Blood Glucose; Blood Urea Nitrogen; Energy Metabolism; Epinephrine; Fem | 1984 |
Triac (3,5,3'-triiodo-thyroacetic acid) induced "pseudohypothyroidism".
Topics: Adult; Female; Humans; Hypothyroidism; Obesity; Thyroid Hormones; Thyrotropin; Triiodothyronine | 1984 |
[Acute hepatitis probably due to Plethoryl].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cyclohexanes; Cyclohexanones; Diterpenes; Drug Combin | 1984 |
Peripheral autoregulation of thyroxine to triiodothyronine conversion in man.
Topics: Female; Humans; Hypothyroidism; Middle Aged; Obesity; Radioimmunoassay; Thyrotropin; Thyroxine; Trii | 1984 |
The effects of corticosterone, cold exposure and overfeeding with sucrose on brown adipose tissue of obese Zucker rats (fa/fa).
Topics: Adipose Tissue, Brown; Adrenalectomy; Animals; Cold Temperature; Corticosterone; Guanosine Diphospha | 1983 |
A metabolic ward study of a high protein, very-low-energy diet.
Topics: 3-Hydroxybutyric Acid; Adult; Body Weight; Diet, Reducing; Dietary Proteins; Electrocardiography; Fe | 1983 |
Thyroid status in the obese syndrome of rats.
Topics: Animals; Kinetics; Male; Mitochondria, Liver; Obesity; Oxidative Phosphorylation; Rats; Rats, Mutant | 1983 |
Direct effect of triiodothyronine on glucose utilization in adipocytes from obese and nonobese Zucker rats.
Topics: Adipose Tissue; Animals; Deoxyglucose; Epididymis; Glucose; Male; Obesity; Oxygen Consumption; Rats; | 1984 |
Resting metabolic rates of obese women after rapid weight loss.
Topics: Adult; Body Weight; Diet, Reducing; Energy Intake; Energy Metabolism; Female; Humans; Obesity; Oxyge | 1984 |
Hepatic conversion of thyroxine to triiodothyronine in obese and lean Zucker rats.
Topics: Animals; Fasting; Liver; Obesity; Rats; Rats, Zucker; Thyroxine; Time Factors; Triiodothyronine | 1984 |
Study of lipoprotein lipase content in Ob17 preadipocytes during adipose conversion. Immunofluorescent localization of the enzyme.
Topics: Adipose Tissue; Animals; Cell Differentiation; Dose-Response Relationship, Drug; Fluorescent Antibod | 1982 |
[Effect of mazindol (teronac) on various hormonal indicators in children with simple obesity].
Topics: Adolescent; Blood Glucose; Child; Female; Humans; Indoles; Insulin; Male; Mazindol; Obesity; Thyrotr | 1982 |
Nature of suppressed TSH secretion during undernutrition: effect of fasting and refeeding on TSH responses to prolonged TRH infusions.
Topics: Adult; Fasting; Female; Humans; Infusions, Parenteral; Male; Obesity; Thyrotropin; Thyrotropin-Relea | 1980 |
Thyroid and growth responses of young Zucker obese and lean rats to a low protein-high carbohydrate diet.
Topics: Animals; Body Composition; Body Weight; Bone and Bones; Dietary Carbohydrates; Dietary Proteins; Ene | 1980 |
The effect of calorie restriction on serum thyroid hormone binding proteins and free hormone in obese patients.
Topics: Adolescent; Adult; Body Weight; Diet, Reducing; Female; Humans; Male; Middle Aged; Obesity; Serum Al | 1980 |
TSH response to TRH in substantial obesity.
Topics: Adult; Aged; Female; Humans; Middle Aged; Obesity; Thyroglobulin; Thyroid Gland; Thyrotropin; Thyrot | 1980 |
Decrease in serum free triiodothyronine, thyroxine-binding globulin and thyroxine-binding prealbumin whilst taking a very-low-calorie diet.
Topics: Adult; Diet, Reducing; Female; Humans; Male; Middle Aged; Obesity; Prealbumin; Serum Albumin; Serum | 1980 |
Thyroid hormone homeostasis in states of relative caloric deprivation.
Topics: Diet; Dietary Carbohydrates; Dietary Proteins; Energy Intake; Humans; Kinetics; Obesity; Thyroid Hor | 1980 |
Decrease in serum free triiodothyronine after jejuno-ileal bypass for obesity.
Topics: Adult; Female; Humans; Ileum; Jejunum; Male; Middle Aged; Obesity; Serum Globulins; Thyroxine; Thyro | 1981 |
[Circulating thyroid hormones in non-thyroid diseases].
Topics: Adult; Aged; Diabetic Ketoacidosis; Humans; Obesity; Syndrome; Thyroxine; Triiodothyronine | 1981 |
[The behavior of the thyrotropin-releasing hormone test in fasting with and without triiodothyronine administration].
Topics: Adolescent; Adult; Fasting; Female; Humans; Male; Middle Aged; Obesity; Thyrotropin; Thyrotropin-Rel | 1982 |
[Indicators of the thyroid status in obesity depending on the types of the hypothalamo-hypophyseal system reaction].
Topics: Humans; Hypothalamo-Hypophyseal System; Obesity; Pituitary Function Tests; Stimulation, Chemical; Th | 1982 |
Thermogenic drugs for the treatment of obesity: screening using obese rats and mice.
Topics: Animals; Body Weight; Eating; Ephedrine; Ethinyl Estradiol; Male; Mice; Mice, Inbred CBA; Obesity; O | 1983 |
[Statistical evaluation of the levels of thyroid stimulating hormone, thyroxine and triiodothyronine of the serum in control and obese subjects].
Topics: Female; Humans; Male; Obesity; Thyrotropin; Thyroxine; Triiodothyronine | 1983 |
Metabolic responses to fasting and refeeding in lean and genetically obese rats.
Topics: Animals; Body Temperature Regulation; Eating; Energy Metabolism; Fasting; Heterozygote; Homozygote; | 1983 |
Adaptation to hypocaloric feeding: physiologic significance of the fall in serum T3 as measured by the pulse wave arrival time (QKd).
Topics: Adaptation, Physiological; Adult; Diet, Reducing; Electrocardiography; Female; Heart; Humans; Male; | 1983 |
Lowering of serum total T3 during a conventional slimming regime.
Topics: Adolescent; Adult; Diet, Reducing; Female; Humans; Male; Middle Aged; Obesity; Thyroxine; Triiodothy | 1983 |
Increased ketonaemia in hyperthyroidism. Evidence for a beta-adrenergic mechanism.
Topics: Adult; Aged; Alanine; Blood Glucose; Diet, Reducing; Energy Intake; Female; Glucagon; Glycerol; Huma | 1980 |
Metabolic adaptations to starvation, semistarvation, and carbohydrate restriction.
Topics: Adult; Dietary Carbohydrates; Fasting; Glucagon; Glucose; Glutamine; Humans; Hydrocortisone; Insulin | 1981 |
The variability of weight reduction during fasting: predictive value of thyroid hormone measurements.
Topics: Adipose Tissue; Adult; Body Constitution; Body Weight; Fasting; Female; Humans; Male; Middle Aged; O | 1982 |
Factors influencing the acute effect of food on oxygen consumption in the rat.
Topics: Adaptation, Physiological; Animals; Cold Temperature; Eating; Energy Metabolism; Feeding Behavior; M | 1982 |
Serum free triiodothyronine: determinant of the pseudohypercortisolism in obesity?
Topics: 17-Ketosteroids; Female; Humans; Hydrocortisone; Menstruation; Obesity; Thyroxine; Triiodothyronine | 1982 |
Serum free triiodothyronine in obesity.
Topics: Adult; Body Weight; Diet; Female; Humans; Male; Middle Aged; Obesity; Thyroid Gland; Triiodothyronin | 1982 |
[The relation between serum thyroid hormone concentration and weight loss in obese patients treated with a low-calorie diet].
Topics: Adult; Body Weight; Diet, Reducing; Double-Blind Method; Female; Humans; Male; Middle Aged; Obesity; | 1982 |
[Hypothyroidism of central origin corrected by the cessation of Triac therapy].
Topics: Female; Humans; Hypothalamo-Hypophyseal System; Hypothyroidism; Middle Aged; Obesity; Thyroid Hormon | 1982 |
Effects of total fasting in obese women. IV. Response of serum triiodothyronine (T3) and reverse triiodothyronine (rT3) to administered T3.
Topics: Adult; Body Weight; Fasting; Female; Heart Rate; Humans; Obesity; Thyrotropin; Thyroxine; Triiodothy | 1981 |
Changes in thyroid hormones in obese women following jejuno-ileal bypass surgery.
Topics: Adult; Female; Humans; Ileum; Jejunum; Middle Aged; Obesity; Thyroid Hormones; Thyroxine; Triiodothy | 1981 |
The effect of triiodothyronine on weight loss and nitrogen balance of obese patients on a very-low-calorie liquid-formula diet.
Topics: Adult; Body Weight; Creatinine; Diet, Reducing; Female; Humans; Male; Middle Aged; Nitrogen; Obesity | 1981 |
[Effect of various methods of treatment of obesity on the hypothalamo-hypophyseal system and thyroid function].
Topics: Adult; Appetite Depressants; Chlorphentermine; Diet, Reducing; Female; Humans; Hypothalamo-Hypophyse | 1981 |
Metabolic insufficiency as a limiting factor in the dietetic treatment of obesity.
Topics: Achilles Tendon; Adolescent; Adult; Body Weight; Female; Humans; Kinetics; Middle Aged; Obesity; Ref | 1981 |
[Obesity: state of research and therapy].
Topics: Diet, Reducing; Energy Metabolism; Exercise Therapy; Female; Humans; Insulin Resistance; Male; Motiv | 1980 |
The effect of refeeding after semistarvation on catecholamine and thyroid metabolism.
Topics: Adult; Blood Pressure; Catecholamines; Female; Food; Humans; Middle Aged; Norepinephrine; Obesity; P | 1980 |
Thyroid status and effects of 3,5,3' triiodothyroacetic acid and fenproporex in genetically lean and obese female rats.
Topics: Amphetamines; Animals; Appetite Depressants; Body Weight; Eating; Female; Lipids; Obesity; Rats; Thy | 1980 |
The effect of levodopa with carbidopa (Sinemet R) on the metabolic response to semistarvation.
Topics: Adaptation, Physiological; Aromatic Amino Acid Decarboxylase Inhibitors; Basal Metabolism; Carbidopa | 1980 |
Glucagon kinetics in fasting: physiological elevations in serum 3,5,3'-triiodothyronine increase the metabolic clearance rate of glucagon.
Topics: Adult; Diet, Reducing; Energy Intake; Fasting; Female; Glucagon; Humans; Kinetics; Male; Metabolic C | 1980 |
[Mechanisms of T4 hyperthyroidism].
Topics: Aged; Amiodarone; Fasting; Female; Humans; Hyperthyroidism; Obesity; Thyroxine; Triiodothyronine | 1980 |
Altered 3,5,3'-triiodothyronine thyroxine ratio in experimentally induced kwashiorkor and obesity in rats.
Topics: Animals; Body Weight; Diet, Protein-Restricted; Dietary Carbohydrates; Dietary Proteins; Female; Kwa | 1995 |
Early treatment of obese (ob/ob) mice with triiodothyronine increases oxygen consumption and temperature and decreases body fat content.
Topics: Adipose Tissue; Animals; Body Composition; Body Temperature; Body Weight; Insulin; Male; Mice; Mice, | 1994 |
Early treatment of obese (ob/ob) mice with triiodothyronine increases oxidative metabolism in muscle but not in brown adipose tissue or liver.
Topics: Adipose Tissue; Adipose Tissue, Brown; Analysis of Variance; Animals; Body Weight; Cell Count; Cells | 1995 |
Acute effect of low-calorie and low-carbohydrate diet on serum triiodothyronine-response to glucose ingestion and its relation to glucose tolerance.
Topics: Blood Glucose; Diet, Reducing; Dietary Carbohydrates; Energy Intake; Glucose; Glucose Intolerance; H | 1994 |
Polyunsaturated fatty acid regulation of lipogenic enzyme gene expression in liver of genetically obese rat.
Topics: Animals; Blood Glucose; Dietary Fats, Unsaturated; Fatty Acids, Unsaturated; Female; Gene Expression | 1995 |
In vitro substrate utilization for lipid synthesis in liver explants from hyperthyroid chickens.
Topics: Acetates; Alanine; Animals; Carbon Dioxide; Chickens; Diet; Dietary Proteins; Growth; Hyperthyroidis | 1993 |
Changes in thyroid hormone and thyrotrophin in the serum and thyroid glands of developing genetically obese male and female Zucker rats.
Topics: Animals; Female; Male; Obesity; Radioimmunoassay; Rats; Rats, Mutant Strains; Sex Factors; Thyroid G | 1994 |
Effect of dietary lipids and endocrine changes on polyunsaturated fatty acids in phospholipids of pancreas and brown adipose tissue of obese and lean rats.
Topics: Adipose Tissue, Brown; Adrenalectomy; Animals; Dietary Fats; Fatty Acids, Unsaturated; Male; Obesity | 1994 |
Hormonal changes in elderly men with non-insulin-dependent diabetes mellitus and the hormonal relationships to abdominal adiposity.
Topics: Abdomen; Adipose Tissue; Adult; Aged; Aging; Body Constitution; Diabetes Mellitus, Type 2; Follicle | 1994 |
Identification and localization of G-proteins in the clonal adipocyte cell lines HGFu and Ob17.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipocytes; Animals; Cell | 1993 |
Impact of regional and total body composition and hormones on resting energy expenditure in overweight postmenopausal women.
Topics: Absorptiometry, Photon; Androstenedione; Basal Metabolism; Body Composition; Body Mass Index; Calori | 1993 |
Recent advances in the treatment of childhood obesity.
Topics: Adolescent; Analysis of Variance; Behavior Therapy; Body Composition; Body Height; Child; Cholestero | 1993 |
Transport of thyroxine into cultured hepatocytes: effects of mild non-thyroidal illness and calorie restriction in obese subjects.
Topics: Bilirubin; Biological Transport; Cells, Cultured; Diet, Reducing; Fatty Acids, Nonesterified; Furans | 1994 |
Restricted energy intake affects nocturnal body temperature and sleep patterns.
Topics: Adult; Basal Metabolism; Body Temperature; Body Weight; Circadian Rhythm; Diet, Reducing; Energy Int | 1994 |
Intrauterine food restriction is associated with obesity in young rats.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Animals, Suckling; Body Weight; Disease Models, Anim | 1993 |
Metabolic and anthropometric changes in female weight cyclers and controls over a 1-year period.
Topics: Adipose Tissue; Anthropometry; Blood Glucose; Body Composition; Body Image; Diet Records; Diet, Redu | 1993 |
Impaired peripheral thyroid hormone metabolism in genetic obesity.
Topics: Animals; Kinetics; Male; Models, Biological; Obesity; Phenotype; Propylthiouracil; Rats; Rats, Zucke | 1993 |
Low resting metabolic rate in subjects predisposed to obesity: a role for thyroid status.
Topics: Adult; Androstenedione; Body Composition; Calorimetry, Indirect; Causality; Energy Metabolism; Femal | 1996 |
Somatometric and hormonal effects of dexfenfluramine.
Topics: Appetite Depressants; Body Weight; Energy Intake; Female; Fenfluramine; Growth Hormone; Hormones; Hu | 1995 |
Metabolic effects of triiodothyronine replacement during fasting in obese subjects.
Topics: Adult; Blood Glucose; Fasting; Female; Humans; Leucine; Male; Middle Aged; Nitrogen; Obesity; Oxygen | 1996 |
Effects of thyroid hormone on GLUT4 glucose transporter gene expression and NIDDM in rats.
Topics: Animals; Diabetes Mellitus, Type 2; Gene Expression; Glucose Transporter Type 4; Hindlimb; Hyperinsu | 1997 |
Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus.
Topics: Animals; Fasting; Hypothalamo-Hypophyseal System; Leptin; Male; Mice; Neurons; Obesity; Paraventricu | 1997 |
Small doses of triiodothyronine can change some risk factors associated with abdominal obesity.
Topics: Abdomen; Adult; Buttocks; Estradiol; Female; Glucose Clamp Technique; Humans; Obesity; Risk Factors; | 1997 |
[Relationship between body composition and serum thyroid hormone in children aged 8 to 12 years].
Topics: Adipose Tissue; Body Composition; Child; Copper; Female; Humans; Male; Obesity; Thyrotropin; Thyroxi | 1996 |
[Low energy metabolism in persons predisposed to obesity: significance of the thyroid status].
Topics: Adult; Androstenedione; Body Mass Index; Energy Metabolism; Female; Humans; Obesity; Thyroid Hormone | 1998 |
Zinc supplementation on serum levels and hepatic conversion of thyroid hormones in obese (ob/ob) mice.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Iodide Peroxidase; Liver; M | 1998 |
An overweight woman with galactorrhoea.
Topics: Adult; Female; Galactorrhea; Humans; Hyperprolactinemia; Obesity; Self Medication; Triiodothyronine | 1998 |
Prevalence of autoantibodies to thyroglobulin in dogs with nonthyroidal illness.
Topics: Animals; Autoantibodies; Dog Diseases; Dogs; Endocrine System Diseases; Enzyme-Linked Immunosorbent | 1998 |
[Metabolism and the functional activity of the thyroid in patients with chronic tonsillitis and excess body weight].
Topics: Adult; Anthropometry; Biomarkers; Chronic Disease; Female; Humans; Nutritional Status; Obesity; Thyr | 1998 |
Substrate oxidation and thyroid hormone response to the introduction of a high fat diet in formerly obese women.
Topics: Adult; Dietary Fats; Energy Intake; Energy Metabolism; Female; Heart Rate; Humans; Kinetics; Middle | 1998 |
Inhibitory action of oral thyrotropin-releasing hormone on the glucoregulatory response of the oral glucose tolerance test.
Topics: Adult; Blood Glucose; C-Peptide; Female; Glucose Tolerance Test; Homeostasis; Humans; Insulin; Kinet | 1998 |
Long-term calorie restriction reduces energy expenditure in aging monkeys.
Topics: Adipose Tissue; Aging; Animals; Body Composition; Body Constitution; Body Surface Area; Body Weight; | 1999 |
Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypothyroid and hyperthyroid subjects.
Topics: Adult; Analysis of Variance; Body Mass Index; Female; Humans; Hyperthyroidism; Hypothyroidism; Lepti | 1998 |
Effects of a low-calorie diet on resting metabolic rate and serum tri-iodothyronine levels in obese children.
Topics: Adolescent; Child; Diet, Reducing; Energy Metabolism; Female; Humans; Male; Obesity; Triiodothyronin | 1999 |
Relationships between dehydroepiandrosterone-sulphate and anthropometric, metabolic and hormonal variables in a large cohort of obese women.
Topics: Adolescent; Adult; Aged; Androstenedione; Case-Control Studies; Dehydroepiandrosterone Sulfate; Fema | 1999 |
Effects of changes in body weight on carbohydrate metabolism, catecholamine excretion, and thyroid function.
Topics: Adult; Blood Glucose; Body Composition; Carbohydrate Metabolism; Catecholamines; Dopamine; Energy Me | 2000 |
Thyroid and sympathetic influences on plasma leptin in hypothyroidism and hyperthyroidism.
Topics: Female; Humans; Hyperthyroidism; Hypothyroidism; Leptin; Male; Norepinephrine; Obesity; Sympathetic | 2000 |
Do adaptive changes in metabolic rate favor weight regain in weight-reduced individuals? An examination of the set-point theory.
Topics: Aged; Basal Metabolism; Body Composition; Body Mass Index; Calorimetry, Indirect; Diet, Reducing; En | 2000 |
Associations of leptin, insulin resistance and thyroid function with long-term weight loss in dieting obese men.
Topics: Adult; Age Factors; Behavior Therapy; Body Composition; Body Mass Index; Diet, Reducing; Energy Meta | 2000 |
Thyroid function and obesity in children and adolescents.
Topics: Adolescent; Autoantibodies; Child; Child, Preschool; Cohort Studies; Female; Humans; Iodide Peroxida | 2000 |
Fat balance and serum leptin concentrations in normal, hypothyroid, and hyperthyroid rats.
Topics: Adipose Tissue; Animals; Body Composition; Energy Metabolism; Fatty Acids, Nonesterified; Hyperthyro | 2001 |
Effect of dexamethasone on TSH secretion induced by TRH in human obesity.
Topics: Dexamethasone; Glucocorticoids; Humans; Hypothyroidism; Male; Obesity; Thyrotropin; Thyrotropin-Rele | 2001 |
[Adverse effect of 3,5,3 triiodothyroacetic acid in the treatment of obesity].
Topics: Adult; Humans; Middle Aged; Obesity; Thyroid Function Tests; Thyrotropin; Triiodothyronine | 2001 |
Exposure to an obesity-inducing diet early affects the pattern of expression of peroxisome proliferator, retinoic acid, and triiodothyronine nuclear receptors in the rat.
Topics: Adipose Tissue; Animals; Diet; Liver; Male; Nuclear Proteins; Obesity; Rats; Rats, Wistar; Receptors | 2001 |
Changes in lipoprotein(a) levels and hormonal correlations during a weight reduction program.
Topics: Adult; Cholesterol; Cholesterol, LDL; Diet, Reducing; Estradiol; Female; Gonadal Steroid Hormones; H | 2001 |
Associations between weight loss-induced changes in plasma organochlorine concentrations, serum T(3) concentration, and resting metabolic rate.
Topics: Basal Metabolism; Diet; Diet, Reducing; History, Modern 1601-; Humans; Hydrocarbons, Chlorinated; In | 2002 |
Clinical implications of leptin and its potential humoral regulators in long-term low-calorie diet therapy for obese humans.
Topics: Adolescent; Adult; Blood Glucose; Body Mass Index; Diet, Reducing; Energy Intake; Fatty Acids, Nones | 2002 |
Relation of thyroid hormones to body-weight.
Topics: Body Weight; Diet, Reducing; Eating; Humans; Male; Obesity; Thyroxine; Triiodothyronine | 1976 |
Triiodothyronine, T.S.H., and prolactin in obese women.
Topics: Adult; Anorexia Nervosa; Body Weight; Energy Intake; Female; Humans; Ileum; Jejunum; Obesity; Prolac | 1977 |
Effects of total fasting in obese women. I. Response of the thyroid.
Topics: Fasting; Female; Humans; Iodine Radioisotopes; Obesity; Sex Factors; Thyroid Function Tests; Thyroid | 1977 |
Unresponsiveness to exogenous TSH in obesity.
Topics: Achilles Tendon; Adolescent; Adult; Age Factors; Aged; Body Weight; Child; Humans; Iodine Radioisoto | 1977 |
Thyroid and obesity: survey of some function tests in a large obese population.
Topics: Adolescent; Adult; Age Factors; Aged; Body Weight; Female; Humans; Middle Aged; Obesity; Thyroid Dis | 1978 |
The effect of mazindol on metabolic and regulatory changes in obese women during weight reduction.
Topics: Adult; Blood Glucose; Body Weight; Diet, Reducing; Energy Metabolism; Epinephrine; Fatty Acids, None | 1979 |
Effect of dietary composition on fasting-induced changes in serum thyroid hormones and thyrotropin.
Topics: Adult; Diet; Fasting; Female; Humans; Male; Middle Aged; Obesity; Sex Factors; Thyroid Hormones; Thy | 1978 |
[Relationship between thyroid hormones and body weight (TRH-induced thyrotropin secretion in female obesity].
Topics: Adult; Humans; Middle Aged; Obesity; Thyrotropin; Thyrotropin-Releasing Hormone; Triiodothyronine | 1978 |
Effects of obesity, total fasting and re-alimentation on L-thyroxine (T4), 3,5,3'-L-triiodothyronine (T3), 3,3',5'-L-triiodothyronine (rT3), thyroxine binding globulin (TBG), cortisol, thyrotrophin, cortisol binding globulin (CBG), transferrin, alpha 2-ha
Topics: Adult; Complement C3; Fasting; Fatty Acids, Nonesterified; Female; Growth Hormone; Haptoglobins; Hum | 1979 |
The influence of caloric restriction on serum prolactin.
Topics: Adolescent; Adult; Diet; Diet, Reducing; Energy Intake; Female; Humans; Male; Middle Aged; Obesity; | 1979 |
Activity of (Na+ + K+)-ATPase in the liver of animals with experimental obesity.
Topics: Adenosine Triphosphatases; Animals; Aurothioglucose; Diabetes Mellitus; Glycerolphosphate Dehydrogen | 1978 |
[Obesity and pregnancy].
Topics: Adult; Blood; Cholesterol; Female; Humans; Hyperlipidemias; Insulin; Lipoproteins, LDL; Obesity; Pre | 1976 |
Na+ pump activity and nuclear T3 receptors in tissues of genetically obese (ob/ob) mice.
Topics: Animals; Biological Transport, Active; Body Temperature Regulation; Diaphragm; Liver; Male; Mice; Mi | 1979 |
Effect of starvation on the production and peripheral metabolism of 3,3',5'-triiodothyronine in euthyroid obese subjects.
Topics: Female; Humans; Metabolic Clearance Rate; Obesity; Radioimmunoassay; Starvation; Thyroxine; Triiodot | 1978 |
Alterations in basal and TRH-stimulated serum levels of thyrotropin, prolactin, and thyroid hormones in starved obese men.
Topics: Adult; Fasting; Growth Hormone; Humans; Male; Middle Aged; Obesity; Prolactin; Thyroid Hormones; Thy | 1977 |
Malabsorption of thyroid hormones after jejunoileal bypass for obesity.
Topics: Adult; Biological Transport; Female; Humans; Ileum; Intestinal Absorption; Jejunum; Malabsorption Sy | 1979 |
[Obesity and thyroid hormones (author's transl)].
Topics: Adult; Female; Humans; Obesity; Thyroid Hormones; Thyroxine; Triiodothyronine; Triiodothyronine, Rev | 1979 |
[Serum levels of T3 and T4 in diabetic and non-diabetic obese subjects].
Topics: Adult; Diabetes Mellitus; Humans; Middle Aged; Obesity; Thyroxine; Triiodothyronine | 1979 |
The effect of T3 and reverse T3 administration on muscle protein catabolism during fasting as measured by 3-methylhistidine excretion.
Topics: Adult; Fasting; Female; Histidine; Humans; Male; Methylhistidines; Middle Aged; Muscle Proteins; Mus | 1979 |
Abnormal thyroid regulation in chickens with autoimmune thyroiditis.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Chickens; Genotype; Histocompatibility Antigens; Inbre | 1979 |
[The change of thyroid function in the dietary therapy of obesity (author's transl)].
Topics: Adolescent; Adult; Diet, Reducing; Female; Humans; Male; Middle Aged; Obesity; Thyrotropin; Thyroxin | 1979 |
Effects of total fasting in obese women. III. Response of serum thyroid hormones to thyroxine and triiodothyronine administration.
Topics: Blood Pressure; Body Weight; Fasting; Female; Heart Rate; Humans; Obesity; Thyroxine; Triiodothyroni | 1979 |
The effects of beta adrenergic blockade on basal metabolism and peripheral thyroid metabolism.
Topics: Adult; Basal Metabolism; Energy Intake; Humans; Middle Aged; Obesity; Propranolol; Thyroid Gland; Th | 1979 |
[Scleronorm effect on serum levels of TSH, triiodothyronine and thyroxine].
Topics: Adult; Aged; Female; Humans; Hypolipidemic Agents; Middle Aged; Obesity; Thyrotropin; Thyroxine; Tri | 1979 |
["Low triiodothyronine (T3) syndrome": "thyroxine (T4) euthyroidism" evidence (author's transl)].
Topics: Aged; Anorexia Nervosa; Diet, Reducing; Humans; Hypothyroidism; Kidney Diseases; Liver Cirrhosis; Ne | 1979 |
Diurnal changes in serum metabolites and hormones in lean and obese Zucker rats.
Topics: Animals; Blood Glucose; Circadian Rhythm; Corticosterone; Growth Hormone; Hormones; Insulin; Obesity | 1978 |
Effect of starvation on the production and metabolism of thyroxine and triiodothyronine in euthyroid obese patients.
Topics: Adult; Body Weight; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Obesity; Starvation | 1977 |
[Diazoxide in the treatment of obesity].
Topics: Diazoxide; Dietary Proteins; Fenfluramine; Furosemide; Glucagon; Humans; Obesity; Triiodothyronine | 1977 |
Serum thyroid hormone concentrations during prolonged reduction of dietary intake.
Topics: Adult; Diet, Reducing; Energy Intake; Female; Humans; Male; Middle Aged; Obesity; Thyroid Hormones; | 1978 |
Thyroidal hormone metabolism in obesity during semi-starvation.
Topics: Adult; Basal Metabolism; Diet, Reducing; Female; Half-Life; Humans; Middle Aged; Obesity; Thyrotropi | 1978 |
[Action of calcitonin, alone or combined triiodothyronine, on urinary calcium and phosphate levels during fasting].
Topics: Calcitonin; Calcium; Fasting; Humans; Obesity; Phosphorus; Triiodothyronine | 1978 |
The effect of protein and carbohydrate in very low energy diets on thyroid hormone levels in overweight adults [proceedings].
Topics: Adult; Dietary Carbohydrates; Dietary Proteins; Energy Metabolism; Humans; Obesity; Thyroid Hormones | 1978 |
[Indications and results of an additional differentiated pharmacotherapy of obesity].
Topics: Adolescent; Adult; Aged; Biguanides; Diabetes Mellitus; Diet, Reducing; Female; Furosemide; Humans; | 1978 |
[[Calciuria and phosphaturia during fasting. Effect of calcitonin alone or with a thyroid hormonotherapy combination].
Topics: Adolescent; Adult; Aged; Calcitonin; Calcium; Diet, Reducing; Drug Combinations; Drug Synergism; Fas | 1978 |
[Radioimmunologic determination of triiodothyronine in essential obesity].
Topics: Humans; Obesity; Radioimmunoassay; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine-Binding Pro | 1975 |
[The diencephalo-hypophyseo-thyroid axis in essential obesity. Note III. The thyroid T3 response to intravenous TRH].
Topics: Adult; Humans; Hypothalamus; Injections, Intravenous; Obesity; Pituitary Gland; Pituitary Gland, Ant | 1975 |
Decreased serum thyrotropin induced by fasting.
Topics: 17-Hydroxycorticosteroids; Adult; Fasting; Female; Humans; Hydrocortisone; Hypothyroidism; Iodine; M | 1977 |
Studies on obesity. III. effect of triiodothyronine (T3) on thyroglobulin autoantibodies in euthyroid obese subjects.
Topics: Adult; Autoantibodies; Body Weight; Female; Hemagglutination; Humans; Middle Aged; Obesity; Thyroglo | 1976 |
[Use of dextrorotatory thyroid hormones for speeding up weight reduction in obesity].
Topics: Adult; Basal Metabolism; Female; Humans; Male; Obesity; Stereoisomerism; Thyroid Hormones; Thyroxine | 1976 |
[Treatment of obesity. Current data on TRIAC].
Topics: Humans; Obesity; Triiodothyronine | 1976 |
Therapy of obesity with hormones.
Topics: Adult; Animals; Child; Chorionic Gonadotropin; Growth Hormone; Heart Diseases; Humans; Injections, I | 1975 |
Diversion of peripheral thyroxine metabolism from activating to inactivating pathways during complete fasting.
Topics: Adult; Diet; Fasting; Female; Humans; Male; Middle Aged; Obesity; Radioimmunoassay; Thyroxine; Triio | 1975 |
[Overweight and thymo-affective disorders. Results of treatment with Triac].
Topics: Adult; Affective Symptoms; Aged; Drug Evaluation; Female; Humans; Male; Middle Aged; Obesity; Triiod | 1975 |
[T3 thyrotoxicosis in obese patient with enlarged sella and hypothalamohypophyseal disturbances (author's transl)].
Topics: Adult; Female; Humans; Hyperthyroidism; Hypothalamo-Hypophyseal System; Obesity; Pituitary Diseases; | 1975 |
Regulation of hepatic fatty acid synthetase in the obese-hyperglycemic mutant mouse.
Topics: Animals; Fatty Acid Synthases; Half-Life; Hyperglycemia; Liver; Mice; Mice, Inbred C57BL; Mice, Obes | 1975 |
Effect of triiodothyronine on blood lipids in obesity.
Topics: Adult; Aged; Cholesterol; Fatty Acids, Nonesterified; Female; Humans; Lipid Mobilization; Lipids; Li | 1975 |
Effect of caloric restriction and dietary composition of serum T3 and reverse T3 in man.
Topics: Adult; Diet, Reducing; Dietary Carbohydrates; Fasting; Humans; Isomerism; Obesity; Radioimmunoassay; | 1976 |
[Changes in the indexes of "unbound" thyroxin in the treatment of obesity (author's transl)].
Topics: Adult; Female; Humans; Middle Aged; Obesity; Thyroxine; Triiodothyronine | 1976 |
Corticosterone and tri-iodothyronine transport into brain of obese (ob/ob) mice.
Topics: Animals; Biological Transport; Blood Proteins; Brain; Corticosterone; Injections, Intra-Arterial; Li | 1992 |
Toxic internuclear ophthalmoplegia related to antiobesity treatment.
Topics: Adult; Diplopia; Female; Fenfluramine; Humans; Obesity; Ophthalmoplegia; Triiodothyronine | 1992 |
The contribution of body composition, substrates, and hormones to the variability in energy expenditure and substrate utilization in premenopausal women.
Topics: Adolescent; Adult; Blood Glucose; Body Composition; C-Peptide; Calorimetry; Dehydroepiandrosterone; | 1992 |
Decreased T4-to-T3 conversion in brown adipose tissue of Zucker fa/fa pups before the onset of obesity.
Topics: Adipose Tissue, Brown; Aging; Animals; Animals, Suckling; Insulin; Iodide Peroxidase; Liver; Obesity | 1992 |
Effects of diet and phenotype on adipose cellularity and 5'-deiodinase activity of liver and brown adipose tissue of diabetic SHR/N-cp rats.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Body Weight; Cell Count; Diabetes Mellitus; Diabetes | 1991 |
Multicompartmental analysis of triiodothyronine (T3) distribution and metabolism in clinically euthyroid obese individuals.
Topics: Adolescent; Adult; Feces; Female; Humans; Kidney; Liver; Male; Middle Aged; Models, Biological; Musc | 1990 |
Effect of thyroxine and chicken growth hormone on immune function in autoimmune thyroiditis (obese) strain chicks.
Topics: Animals; Cells, Cultured; Chickens; Flow Cytometry; Growth Hormone; Haplotypes; Lymphocyte Activatio | 1992 |
Effects of phenotype, feeding condition and cold exposure on thyrotropin and thyroid hormones of obese and lean mice.
Topics: Animals; Body Temperature; Body Weight; Cold Temperature; Female; Food; Food Deprivation; Male; Mice | 1991 |
[Investigation of the relationships between zinc and obesity].
Topics: Adult; Animals; Female; Humans; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Middle Aged; O | 1991 |
Reduced brown adipose tissue thermogenesis and metabolic rate in pre-obese mice treated with monosodium-L-glutamate.
Topics: Adipose Tissue, Brown; Animals; Basal Metabolism; Body Temperature Regulation; Female; Guanosine Dip | 1991 |
T3 plus high doses of beta-blockers: effects on energy intake, body composition, bat and heart in rats.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adrenergic beta-Antagonists; Animals; Atenolol; Body Composit | 1990 |
Obesity-related hypertension: evaluation of the separate effects of energy restriction and weight reduction on hemodynamic and neuroendocrine status.
Topics: Aged; Blood Pressure; Body Weight; Catecholamines; Diet, Reducing; Energy Intake; Female; Humans; Hy | 1991 |
Resting metabolic rate, body composition and thyroid hormones. Short term effects of very low calorie diet.
Topics: Adult; Basal Metabolism; Body Composition; Diet, Reducing; Energy Intake; Female; Humans; Obesity; T | 1990 |
The effect of triiodothyronine on glucose utilization in adipocytes from obese rats.
Topics: Adipose Tissue; Animals; Deoxyglucose; Glucose; Insulin; Male; Obesity; Rats; Rats, Zucker; Time Fac | 1990 |
[Factors affecting normal levels of insulin, cortisol, STH, thyroxine and triiodothyronine].
Topics: Adult; Growth Hormone; Hormones; Humans; Hydrocortisone; Insulin; Obesity; Reference Values; Thyroxi | 1990 |
Effects of sucrose on resting metabolic rate, nitrogen balance, leucine turnover and oxidation during weight loss with low calorie diets.
Topics: Adult; Blood Glucose; Body Temperature Regulation; Diet, Reducing; Dietary Fats; Dietary Proteins; E | 1990 |
Measurement of composition changes using dual-photon absorptiometry in obese patients undergoing semistarvation.
Topics: Absorptiometry, Photon; Adult; Body Composition; Body Water; Diet, Reducing; Energy Intake; Female; | 1990 |
Lipolysis in isolated epididymal adipocytes from genetically obese Zucker rat treated with 3,5,3'-L-triiodothyronine.
Topics: Adipose Tissue; Animals; Epididymis; Epinephrine; Glycerol; Isoproterenol; Lipolysis; Male; Obesity; | 1990 |
Antioxidants delay the onset of thyroiditis in obese strain chickens.
Topics: Animals; Antioxidants; Autoantibodies; Butylated Hydroxyanisole; Chickens; Ethoxyquin; Obesity; Thyr | 1990 |
[Probable side effects caused by plethoryl. Common acute hepatitis, anicteric hepatitis, cirrhosis due to hypervitaminosis A, inflammatory arthralgias].
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Cyclohexanes; | 1989 |
Effects of dietary carbohydrate and phenotype on thyroid hormones and brown adipose tissue locularity in adult LA/N-cp rats.
Topics: Adipose Tissue, Brown; Animals; Dietary Carbohydrates; Lipid Metabolism; Obesity; Phenotype; Radioim | 1989 |
Cardiac stroke work output during a short term very low calorie diet, noradrenaline-induced thermogenesis and T3 supplementation.
Topics: Cardiac Output; Diet, Reducing; Energy Intake; Humans; Norepinephrine; Obesity; Triiodothyronine | 1989 |
Reverse T3 changes during protein supplemented diets. Relation to nutrient combustion rates.
Topics: Adult; Calorimetry; Creatinine; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Female; | 1989 |
[Results of weight-loss treatment at a hospital. Significance of the administration of triiodothyronine in small doses during a protein diet].
Topics: Adult; Diet, Reducing; Dietary Proteins; Female; Food, Formulated; Hospitalization; Humans; Male; Mi | 1989 |
Effect of triiodothyronine on leucine kinetics, metabolic rate, glucose concentration and insulin secretion rate during two weeks of fasting in obese women.
Topics: Adult; Blood Glucose; Fasting; Female; Humans; Insulin; Insulin Secretion; Leucine; Obesity; Triiodo | 1989 |
Studies of 5'-deiodinase activity in rats differing in hepatic lipogenic activity.
Topics: Adrenalectomy; Animals; Food; Hydrocortisone; Iodide Peroxidase; Lipids; Liver; Obesity; Rats; Rats, | 1989 |
The influence of caloric deprivation and food composition on TSH, thyroid hormones and nuclear binding of T3 in mononuclear blood cells in obese women.
Topics: Adult; Cell Nucleus; Diet; Diet, Reducing; Energy Intake; Female; Humans; Leukocytes, Mononuclear; M | 1989 |
Skeletal muscle metabolism: effect of age, obesity, thyroid and nutritional status.
Topics: Aging; Animals; Biological Transport, Active; Energy Metabolism; Female; Male; Mice; Mice, Inbred BA | 1989 |
Thyroid hormone responses to feeding in ob/ob mice.
Topics: Analysis of Variance; Animals; Body Temperature; Eating; Energy Metabolism; Female; Food Deprivation | 1989 |
Hormonal studies of young lean and obese Zucker rats.
Topics: Animals; Blood Glucose; Corticosterone; Fasting; Female; Hormones; Insulin; Obesity; Pancreas; Rats; | 1986 |
[Comparison of the lipolytic activity of adipocytes isolated from white adipose tissue in Zucker and Wistar rats. In vitro effects of 3,5,3'-triiodo-L-thyronine].
Topics: Adipose Tissue; Animals; Epinephrine; Hypothyroidism; Lipolysis; Male; Obesity; Rats; Rats, Inbred S | 1986 |
[Hormones of the pituitary-thyroid axis in obese subjects on free and low-calorie diet].
Topics: Adolescent; Adult; Female; Humans; Male; Obesity; Thyrotropin; Thyroxine; Triiodothyronine | 1987 |
Fasting induces the generation of serum thyronine-binding globulin in Zucker rats.
Topics: Animals; Body Weight; Fasting; Iodine Radioisotopes; Male; Obesity; Phenytoin; Rats; Rats, Mutant St | 1985 |
Post prandial thermogenesis in different pathophysiological conditions.
Topics: Aging; Animals; Anorexia Nervosa; Body Composition; Dietary Carbohydrates; Dietary Fiber; Eating; En | 1986 |
Low serum free T3 concentrations in postobese patients previously treated with very-low-calorie diet.
Topics: Adult; Energy Intake; Humans; Middle Aged; Obesity; Stomach; Thyroxine-Binding Proteins; Triiodothyr | 1987 |
Prolactin and thyroid status in prepubertal children with mild to moderate obesity.
Topics: Child; Female; Humans; Male; Obesity; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxi | 1988 |
Thyroid hormones in genetically lean or fat chickens: effects of age and triiodothyronine supplementation.
Topics: Aging; Animals; Body Weight; Chickens; Female; Male; Obesity; Sex Factors; Species Specificity; Thyr | 1988 |
Metabolic and thyroidal responses to mild cold are abnormal in obese diabetic women.
Topics: Adult; Cold Temperature; Diabetes Mellitus; Diabetes Mellitus, Type 2; Energy Metabolism; Female; Hu | 1988 |
Normalization of serum sex hormone-binding globulin by L-thyroxine in obese women.
Topics: Adolescent; Adult; Body Weight; Female; Humans; Hypothyroidism; Obesity; Sex Hormone-Binding Globuli | 1988 |
Altered triiodothyronine metabolism in Zucker fatty rats.
Topics: Animals; Body Weight; Eating; Genotype; Iodide Peroxidase; Male; Metabolic Clearance Rate; Obesity; | 1988 |
Hereditary and environmental influences on the variation of thyroid hormones in normal male twins.
Topics: Humans; Male; Obesity; Reference Values; Seasons; Thyroglobulin; Thyroid Hormones; Thyrotropin; Thyr | 1988 |
Dissociated thyromimetic effects of 3, 5, 3'-triiodothyroacetic acid (TRIAC) at the pituitary and peripheral tissue levels.
Topics: Adult; Body Weight; Double-Blind Method; Female; Heart Rate; Humans; Lipids; Obesity; Random Allocat | 1988 |
Impaired transport of thyroid hormones into livers of obese (ob/ob) mice.
Topics: Animals; Biological Transport, Active; Hydrocortisone; Liver; Mice; Mice, Inbred C57BL; Mice, Obese; | 1988 |
Serum concentrations of total and free thyroid hormones in moderately obese women during a six-week slimming cure.
Topics: Adolescent; Adult; Body Constitution; Diet, Reducing; Female; Humans; Obesity; Thyroid Hormones; Thy | 1988 |
Metabolic studies in human obesity during overnutrition and undernutrition: thermogenic and hormonal responses to norepinephrine.
Topics: Adult; Basal Metabolism; Body Composition; Body Temperature Regulation; Energy Metabolism; Feeding a | 1986 |
Nitrogen conservation in starvation revisited: protein sparing with intravenous fructose.
Topics: Acid-Base Equilibrium; Adult; Amino Acids; Blood Glucose; Fasting; Female; Fructose; Glucagon; Human | 1986 |
Effects of obesity on insulin and glucose metabolism in cyclic heifers.
Topics: Animals; Blood Glucose; Cattle; Cattle Diseases; Diestrus; Estradiol; Estrus; Female; Glucose; Insul | 1986 |
[The oral glucose tolerance test combined with the determination of insulin, cortisol, growth hormone, thyroxine and triiodothyronine in obese women. I. Results from the entire group].
Topics: Adult; Blood Glucose; Female; Glucose Tolerance Test; Growth Hormone; Hormones; Humans; Hydrocortiso | 1986 |
The incorporation of dietary iodine into thyroglobulin increases its immunogenicity.
Topics: Animals; Antibodies; Antibody Specificity; Antigens; Autoantibodies; Chickens; Diet; Immunization; I | 1987 |
Comparative effects of 3,5-dimethyl-3'-isopropyl-L-thyronine (DIMIT) and 3,5-diiodo-3'-isopropylthyroacetic acid (IpTA2) on body weight gain and lipid metabolism in genetically obese Zucker rats.
Topics: Animals; Body Weight; DNA-Directed RNA Polymerases; Female; Lipid Metabolism; Liver; Obesity; Rats; | 1986 |
Effect of glucose administration on thyroid hormones and oxygen consumption in normal and obese subjects.
Topics: Adult; Energy Metabolism; Female; Glucose; Humans; Male; Obesity; Oxygen Consumption; Thyroid Hormon | 1986 |
Sucrose substitution in prevention and reversal of the fall in metabolic rate accompanying hypocaloric diets.
Topics: Adult; Body Weight; Diet, Reducing; Energy Intake; Energy Metabolism; Female; Humans; Norepinephrine | 1986 |
Effects of caloric deprivation on thyroid hormone tissue uptake and generation of low-T3 syndrome.
Topics: Adult; Diet, Reducing; Energy Intake; Female; Humans; Iodide Peroxidase; Iodine Radioisotopes; Kinet | 1986 |
[Fatal fulminant hepatitis probably due to Plethoryl].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cyclohexanes; Cyclohexanones; Diterpenes; Drug Combin | 1986 |
Triiodothyronine (T3)-induced down-regulation of the nuclear T3 receptor in mouse preadipocyte cell lines.
Topics: Adipose Tissue; Animals; Cell Line; Cell Nucleus; Kinetics; Male; Mice; Mice, Obese; Obesity; Recept | 1986 |
Triiodothyronine (T3) neogenesis in lean and obese LA/N-cp rats.
Topics: Adipose Tissue; Animals; Body Temperature Regulation; Body Weight; Iodide Peroxidase; Obesity; Oxyge | 1986 |
Serum lipids and lipoproteins in hypothyroidism.
Topics: Animals; Body Weight; Chickens; Estrone; Fatty Acids; Hypothyroidism; Lipids; Lipoproteins; Obesity; | 1986 |
Influence of thyroid status on body weight gain, food intake and serum lipid levels in genetically obese Zucker rats.
Topics: Animals; Body Weight; Eating; Female; Lipids; Obesity; Rats; Rats, Zucker; Thyroid Gland; Triiodothy | 1987 |
The effects of triiodothyronine on energy expenditure, nitrogen balance and rates of weight and fat loss in obese patients during prolonged caloric restriction.
Topics: Adolescent; Adult; Body Weight; Energy Intake; Energy Metabolism; Female; Humans; Male; Middle Aged; | 1985 |
The effect of tri-iodothyronine (T3) on protein turnover and metabolic rate.
Topics: Adult; Ammonia; Body Weight; Creatinine; Diet Therapy; Female; Humans; Metabolism; Obesity; Triiodot | 1985 |
[Hormonal evaluation of the functional state of the gonads, thyroid and adrenal glands in obese children].
Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Hormones; Child; Female; Gonadal Steroid Hormones; Humans | 1985 |
The thermic effect of carbohydrate versus fat feeding in man.
Topics: Adolescent; Adult; Basal Metabolism; Biotransformation; Blood Glucose; Dietary Carbohydrates; Dietar | 1985 |
Decreased serum reverse triiodothyronine levels with major weight loss in obese women.
Topics: Adult; Body Weight; Female; Humans; Obesity; Serum Albumin; Stomach; Thyroxine; Thyroxine-Binding Pr | 1985 |
Decreased prolactin secretion in childhood obesity.
Topics: Adolescent; Blood Glucose; Child; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypothal | 1985 |
Disparity of thyrotropin (TSH) and prolactin responses to TSH-releasing hormone in obesity.
Topics: Adolescent; Adult; Estradiol; Female; Humans; Kinetics; Middle Aged; Obesity; Prolactin; Thyrotropin | 1985 |
Studies on the diurnal pattern of serum 3,5,3'-triiodothyronine.
Topics: Adult; Circadian Rhythm; Fasting; Female; Humans; Male; Obesity; Reference Values; Thyrotropin; Thyr | 1986 |
Decrease of circulating level of SHBG in postmenopausal obese women as a risk factor in breast cancer: reversible effect of weight loss.
Topics: Aged; Androstenedione; Body Weight; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Hydrocorti | 1986 |
Decreased triiodothyronine binding to isolated nuclei from livers of preobese and obese (ob/ob) mice.
Topics: Aging; Animals; Body Temperature Regulation; Cell Nucleus; Liver; Mice; Mice, Obese; Obesity; Triiod | 1986 |
Some quantitative changes in iodothyronine distribution and metabolism in mild obesity and aging.
Topics: Aging; Animals; Body Weight; Dietary Fats; Kinetics; Male; Obesity; Rats; Rats, Inbred Strains; Thyr | 1985 |
Hepatic delta 6-desaturase activity in lean and genetically obese ob/ob mice.
Topics: Animals; Brain; Fatty Acid Desaturases; Food; Hypothyroidism; Linoleoyl-CoA Desaturase; Liver; Mice; | 1985 |
Relationship between the changes in serum thyroid hormone levels and protein status during prolonged protein supplemented caloric deprivation.
Topics: Adult; Diet, Reducing; Dietary Proteins; Energy Intake; Humans; Male; Methylhistidines; Middle Aged; | 1985 |
[Serum dopamine beta-hydroxylase activity in obesity and during a two-week fasting period].
Topics: Adult; Body Weight; Diet, Reducing; Dopamine beta-Hydroxylase; Energy Metabolism; Fasting; Female; H | 1985 |
Enhanced thermogenic responsiveness during chronic ephedrine treatment in man.
Topics: Adipose Tissue, Brown; Adolescent; Adult; Blood Glucose; Blood Pressure; Body Temperature Regulation | 1985 |
[Behavior of several hormonal and nonhormonal parameters in obesity. II. Thyroid hormones (free T3, free T4, rT3)].
Topics: Adult; Female; Humans; Male; Obesity; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1985 |
Blood parameters and body composition in fetuses from reciprocal crosses of genetically lean and obese swine.
Topics: Animals; Body Composition; Crosses, Genetic; Female; Fetal Blood; Fetus; Growth Hormone; Hydrocortis | 1985 |
Food restriction increases torpor and improves brown adipose tissue thermogenesis in ob/ob mice.
Topics: Adipose Tissue, Brown; Animals; Basal Metabolism; Body Temperature; Body Weight; Circadian Rhythm; E | 1985 |
Serum concentrations of total T4, T3, reverse T3 and free T4, T3 in moderately obese patients.
Topics: Adolescent; Adult; Body Weight; Female; Humans; Male; Middle Aged; Obesity; Thyroid Hormones; Thyrox | 1985 |
Renal concentrating ability in obesity. Effect of modified fasting and the supplementation of T3, sodium chloride and carbohydrate.
Topics: Adult; Creatinine; Dietary Carbohydrates; Fasting; Female; Humans; Kidney Concentrating Ability; Mal | 1985 |
Plasma thyroid hormones, growth and carcass measurements of genetically obese and lean pigs as influenced by thyroprotein supplementation.
Topics: Animals; Body Temperature Regulation; Body Weight; Caseins; Female; Iodoproteins; Obesity; Swine; Th | 1985 |
Fetal hormone and metabolite levels in lean and obese pigs.
Topics: Adipose Tissue; Animals; Blood Glucose; Female; Fetus; Glucagon; Growth Hormone; Hormones; Hydrocort | 1985 |
Indices of unbound thyroxine in obese women.
Topics: Adult; Binding Sites; Fatty Acids, Nonesterified; Female; Humans; Obesity; Serum Globulins; Thyroid | 1972 |
The primary empty sella: clinical and radiographic characteristics and endocrine function.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Aged; Cholesterol; Female; Gonadotrop | 1973 |
Occurrence of hyperthyroidism in patients receiving thyroid hormone.
Topics: Adolescent; Adult; Alopecia; Antithyroid Agents; Fatigue; Female; Goiter; Graves Disease; Humans; Hy | 1967 |
[On the problem of thyroid gland function in obesity].
Topics: Adolescent; Adult; Aged; Chromatography, Gel; Dextrans; Female; Humans; Male; Middle Aged; Obesity; | 1967 |
[Serum hormone iodine in alimentary obesity].
Topics: Adolescent; Adult; Aged; Body Height; Body Weight; Disease Reservoirs; Female; Germany, West; Goiter | 1968 |
[Radioimmunoassay of plasma triiodothyroneine in normal and different pathological cases in children].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Female; Humans; Hyperthyroidism; Hypothyroidism; I | 1974 |
[Results of examinations of obese children and adolescents using the T3 test. Preliminary report].
Topics: Adolescent; Child; Child, Preschool; Cholesterol; Female; Humans; Male; Obesity; Protein Binding; Tr | 1974 |
The influence of total starvation on the pituitary-thyroid-axis in obese individuals.
Topics: Female; Humans; Male; Obesity; Pituitary Gland; Starvation; Thyroid Gland; Thyrotropin; Thyroxine; T | 1973 |
[Indexes of unbound thyroxine in obese women].
Topics: Adult; Female; Humans; Obesity; Protein Binding; Thyroxine; Thyroxine-Binding Proteins; Triiodothyro | 1972 |
[Gout and hyperuricemia during fasting. Action of associated thyroid hormone therapy].
Topics: Adolescent; Adult; Fasting; Female; Gout; Humans; Male; Middle Aged; Obesity; Triiodothyronine; Uric | 1973 |
Peripheral metabolism of thyroxine and triiodothyronine in patients with endemic goitre, natives of endemic goitre areas in Czechoslovakia (with regard to obesity).
Topics: Czechoslovakia; Disease Reservoirs; Feces; Female; Goiter, Endemic; Humans; Hyperthyroidism; Hypothy | 1973 |
Diet and obesity.
Topics: Adolescent; Basal Metabolism; Diet; Diet, Reducing; Feeding Behavior; Female; Humans; Male; Middle A | 1973 |
[Clinical aspects and treatment of pubertal-adolescent dyspituitarism].
Topics: Adolescent; Adult; Body Weight; Cushing Syndrome; Diagnosis, Differential; Female; Humans; Male; Obe | 1973 |
Balanced low-calorie vs. low-protein-low-carbohydrate reducing diets. II. Biochemical changes.
Topics: Acidosis; Adult; Appetite; Blood Glucose; Blood Urea Nitrogen; Diet, Reducing; Dietary Carbohydrates | 1974 |
[Effect of fasting on phosphorus-calcium metabolism. Action of associated thyroid hormonotherapy].
Topics: Adolescent; Adult; Alkaline Phosphatase; Body Weight; Calcium; Diet Therapy; Fasting; Female; Humans | 1974 |
[Effectiveness of small doses of thyroid hormones in the treatment of obesity].
Topics: Body Weight; Female; Humans; Obesity; Thyroglobulin; Triiodothyronine | 1974 |
The effect of starvation on the concentration and binding of thyroxine and triiodothyronine in serum and on the response to TRH.
Topics: Adult; Female; Humans; Male; Middle Aged; Obesity; Prospective Studies; Starvation; Thyrotropin; Thy | 1974 |
Experience with a hospital-based weight reduction program.
Topics: Adult; Allied Health Personnel; Anthropometry; Body Weight; Cholesterol; Diet, Reducing; Female; Hos | 1972 |
An approach to the problem of obesity.
Topics: Humans; Obesity; Triiodothyronine | 1969 |
[Thyroid hormones in obesity].
Topics: Glucose; Humans; Obesity; Triiodothyronine | 1968 |
Effect of weight reduction, triiodothyronine, and diethylstilbestrol on growth hormone in obesity.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Body Weight; Diethylstilbestrol; Female; Growth Hormone; | 1969 |
[Lipogenesis and lipolysis].
Topics: Body Weight; Epinephrine; Hormones; Humans; Lipase; Lipidoses; Obesity; Pituitary Gland; Triiodothyr | 1970 |
[Achilles tendon reflexometry in the diagnosis of thyroid gland diseases].
Topics: Achilles Tendon; Adolescent; Diagnosis, Differential; Female; Humans; Hyperthyroidism; Hypophysectom | 1971 |
[Contribution of the General Hospital of the National Medical Center to medicine. VI. Management of obesity by complete fasting. II. Influence of some hormone factors in the prolonged fast-breaking syndrome in humans].
Topics: Anabolic Agents; Carbohydrate Metabolism; Fasting; Humans; Insulin; Insulin Secretion; Lipid Metabol | 1967 |
[Hyperthyroidism, overfeeding and diabetes mellitus].
Topics: Adult; Diabetes Mellitus; Diet Therapy; Diet, Reducing; Humans; Hyperthyroidism; Male; Middle Aged; | 1967 |
[Comparative study of the clinical and metabolic effects of triiodothyropropionic acid and of L-triiodothyronine].
Topics: Adolescent; Adult; Basal Metabolism; Body Weight; Cholesterol; Female; Goiter; Humans; Hyperthyroidi | 1968 |
Fasting in obese females. I. A study of thyroid function tests, serum proteins and electrolytes.
Topics: Adolescent; Adult; Blood Protein Electrophoresis; Blood Proteins; Calcium; Fasting; Female; Humans; | 1968 |
[Are thyroid gland preparations indicated in the treatment of obesity?].
Topics: Adolescent; Adult; Aged; Ambulatory Care; Appetite Depressants; Diet, Reducing; Electrocardiography; | 1968 |
Canine thyroid function in adiposity and certain skin ailments studied by the EU test.
Topics: Animals; Dog Diseases; Dogs; Erythrocytes; Iodine Isotopes; Obesity; Skin Diseases; Thyroid Gland; T | 1968 |
[On the lipolytic effect of adrenaline in adipositas prior and following triiodothyronine].
Topics: Adolescent; Adult; Body Weight; Epinephrine; Fatty Acids, Nonesterified; Female; Humans; Lipids; Mal | 1968 |
The effects of L-triiodothyronine on the fatty acid composition of adipose tissue and on some metabolic parametres of obese individuals.
Topics: Adipose Tissue; Adult; Aged; Blood Glucose; Fats, Unsaturated; Fatty Acids; Humans; Middle Aged; Obe | 1969 |
Effect of diet and triiodothyronine on the activity of sn-glycerol-3-phosphate dehydrogenase and on the metabolism of glucose and pyruvate by adipose tissue of obese patients.
Topics: Adipose Tissue; Adolescent; Adult; Biopsy; Body Weight; Carbon Dioxide; Carbon Isotopes; Diet, Reduc | 1969 |
Altered composition and lipolysis of adipose tissue from gold thioglucose obese mice.
Topics: Adipose Tissue; Animals; Body Weight; Cortisone; Epinephrine; Fatty Acids, Nonesterified; Glucose; G | 1969 |