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triiodothyronine and Nephrotic Syndrome

triiodothyronine has been researched along with Nephrotic Syndrome in 31 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to investigate the effects of low triiodothyronine syndrome (LT3S) on platelet function and clotting factors in patients with nephrotic syndrome(NS)."7.91Low triiodothyronine syndrome is associated with platelet function in patients with nephrotic syndrome. ( Chen, X; Guo, N; Wu, J; Xing, C, 2019)
"Triamcinolone treatment did not affect plasma protein and albumin levels but increased the level of plasma triglycerides and cholesterol in the very low density lipoprotein (VLDL) and LDL but not high density lipoprotein fractions."5.29Hyperlipoproteinemia of aminonucleoside-induced nephrotic syndrome--modulation by glucocorticoids and triiodothyronine. ( Shafrir, E, 1996)
" A diagnosis of autoimmune thyroiditis (AT) in thyrotoxic phase was made on the basis of clinical presentation and presence of anti-TPO antibodies and reduced uptake in thyroid (technetium) scintigraphy."3.91Auto-immune Thyroiditis in an Infant Masquerading as Congenital Nephrotic Syndrome. ( Bavdekar, SB; Jondhale, SN; Koppikar, RG; Save, SU, 2019)
"The objective of this study was to investigate the effects of low triiodothyronine syndrome (LT3S) on platelet function and clotting factors in patients with nephrotic syndrome(NS)."3.91Low triiodothyronine syndrome is associated with platelet function in patients with nephrotic syndrome. ( Chen, X; Guo, N; Wu, J; Xing, C, 2019)
" Four had primary hypothyroidism as defined by low serum free tri-iodothyronine (FT3) and free thyroxine (FT4), and high serum thyroid-stimulating hormone (TSH) levels."3.69Hypothyroidism in infants with nephrotic syndrome. ( Mattoo, TK, 1994)
" Hypothyroidism resolved on remission of nephrotic syndrome in two patients; thyroxine (T4) replacement was ineffective during periods of gross proteinuria in another, and the fourth had had normal thyroid function a year before presentation."3.68Can urinary thyroid hormone loss cause hypothyroidism? ( Fonseca, V; Katrak, A; Moorhead, JF; Sweny, P; Thomas, M, 1991)
"To evaluate reverse 3,3',5'-triiodothyronine (rT3) metabolism in nephrotic syndrome, serum rT3 kinetic studies from 10 nephrotics (mean urinary protein losses 7."3.68rT3 metabolism in patients with nephrotic syndrome and normal GFR compared with normal subjects. ( Hoopes, MT; Kaptein, EM; Massry, SG; Parise, M, 1991)
"Total serum and urinary thyroxine (T4), triiodothyronine (T3), and thyroxine-binding globulin (TBG) as well as serum free T4, thyroid-stimulating hormone (TSH), and T3 resin uptake (T3RU) were measured in seven patients with the nephrotic syndrome."3.66Thyroid function studies in the nephrotic syndrome. ( Afrasiabi, MA; Barton, CH; Gwinup, G; Mays, DM; Ness, RL; Valenta, LJ; Vaziri, ND, 1979)
"Overt hypothyroidism was defined as low FT4 (normal values: 0."1.40Subclinical non-autoimmune hypothyroidism in children with steroid resistant nephrotic syndrome. ( Batra, V; Dubey, NK; Goyal, P; Kapoor, K; Saha, A; Suresh, CP; Upadhayay, AD, 2014)
"Triamcinolone treatment did not affect plasma protein and albumin levels but increased the level of plasma triglycerides and cholesterol in the very low density lipoprotein (VLDL) and LDL but not high density lipoprotein fractions."1.29Hyperlipoproteinemia of aminonucleoside-induced nephrotic syndrome--modulation by glucocorticoids and triiodothyronine. ( Shafrir, E, 1996)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199015 (48.39)18.7374
1990's8 (25.81)18.2507
2000's2 (6.45)29.6817
2010's6 (19.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jondhale, SN1
Save, SU1
Koppikar, RG1
Bavdekar, SB1
Wu, J1
Guo, N1
Chen, X1
Xing, C1
Bunevicius, A1
Kapoor, K1
Saha, A1
Dubey, NK1
Goyal, P1
Suresh, CP1
Batra, V1
Upadhayay, AD1
Sharma, S1
Dabla, PK1
Kumar, M1
Afroz, S1
Khan, AH1
Roy, DK1
Liu, JH1
Yi, ZW1
CLARK, F1
HORN, DB1
Ieiri, T1
Hamamoto, K1
Oyemade, OA1
Lukanmbi, FA1
Osotimehin, BO1
Dada, OA1
Adlkofer, F1
Hain, H1
Meinhold, H1
Kraft, D1
Ramsden, D1
Herrmann, J1
Heller, WD1
Kaptein, EM2
Feinstein, EI1
Massry, SG2
Mayer, M2
Amin, R1
Shafrir, E3
Mattoo, TK1
Ito, S1
Kano, K1
Ando, T1
Ichimura, T1
Medina-Campos, ON1
Pedraza-Chaverrí, J1
Correa-Rotter, R1
Ibarra-Rubio, ME1
Chadha, V1
Alon, US1
Afrasiabi, MA1
Vaziri, ND1
Gwinup, G1
Mays, DM1
Barton, CH1
Ness, RL1
Valenta, LJ1
Feldman, JM1
Fonseca, V1
Thomas, M1
Katrak, A1
Sweny, P1
Moorhead, JF1
Carpi, A1
Romano, F1
Massitelli, M1
Ciardella, F1
Hoopes, MT1
Parise, M1
Słuszkiewicz, E1
Senda, H1
Imaeda, T1
Reinwein, D1
Földes, J1
Lengyel, Z1
Gesztesi, E1
Takács, I1
el-Shawarbi, K1
Megahed, YM1
Sadek, S1
Green, WL1
Brenner, T1
Gutman, A1
Orevi, M1
Diamant, S1

Reviews

4 reviews available for triiodothyronine and Nephrotic Syndrome

ArticleYear
[Thyroxine binding globulin (TBG), triiodothyronine uptake (T3U), thyroxine binding capacity (TBC)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8

    Topics: Biomarkers; Diabetic Ketoacidosis; Humans; Hyperthyroidism; Hypothyroidism; Immunoassay; Liver Disea

2005
Thyroid hormone metabolism in renal diseases.
    Contributions to nephrology, 1982, Volume: 33

    Topics: Acute Kidney Injury; Humans; Kidney Diseases; Nephrotic Syndrome; Thyroid Hormones; Thyroxine; Thyro

1982
[Differential diagnostic significance of thyroid hormone and TSH determination].
    Medizinische Klinik, 1972, Dec-01, Volume: 67, Issue:48

    Topics: Antithyroid Agents; Diagnosis, Differential; Goiter; Heparin; Humans; Hyperthyroidism; Hypothyroidis

1972
Guidelines for the treatment of myxedema.
    The Medical clinics of North America, 1968, Volume: 52, Issue:2

    Topics: Adult; Basal Metabolism; Blood Proteins; Child, Preschool; Coma; Female; Humans; Myxedema; Nephrotic

1968

Trials

1 trial available for triiodothyronine and Nephrotic Syndrome

ArticleYear
Low protein supplemented diet corrects altered serum thyroid hormone and TSH concentrations in patients with chronic nephrotic syndrome.
    Thyroidology, 1990, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Amino Acids; Creatinine; Female; Humans; Nephrotic Syndrome; Parathyroid Hormone;

1990

Other Studies

26 other studies available for triiodothyronine and Nephrotic Syndrome

ArticleYear
Auto-immune Thyroiditis in an Infant Masquerading as Congenital Nephrotic Syndrome.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:2

    Topics: Carbimazole; Female; Hashimoto Disease; Humans; Hyperthyroidism; Hypertriglyceridemia; Hypoalbuminem

2019
Low triiodothyronine syndrome is associated with platelet function in patients with nephrotic syndrome.
    Revista da Associacao Medica Brasileira (1992), 2019, Aug-05, Volume: 65, Issue:7

    Topics: Adult; Blood Platelets; Euthyroid Sick Syndromes; Female; Flow Cytometry; Humans; Male; Middle Aged;

2019
Comments: "Low triiodothyronine syndrome is associated with platelet function in patients with nephrotic syndrome".
    Revista da Associacao Medica Brasileira (1992), 2019, 08-05, Volume: 65, Issue:7

    Topics: Euthyroid Sick Syndromes; Hemostasis; Humans; Nephrotic Syndrome; Triiodothyronine

2019
Subclinical non-autoimmune hypothyroidism in children with steroid resistant nephrotic syndrome.
    Clinical and experimental nephrology, 2014, Volume: 18, Issue:1

    Topics: Adolescent; Asymptomatic Diseases; Biomarkers; Case-Control Studies; Child; Child, Preschool; Cross-

2014
Evaluation of Thyroid Hormone Status in Children with Steroid Resistant Nephrotic Syndrome: A North India Study.
    Endocrine, metabolic & immune disorders drug targets, 2015, Volume: 15, Issue:4

    Topics: Asymptomatic Diseases; Child; Child, Preschool; Creatinine; Cross-Sectional Studies; Disease Progres

2015
Thyroid function in children with nephrotic syndrome.
    Mymensingh medical journal : MMJ, 2011, Volume: 20, Issue:3

    Topics: Child; Child, Preschool; Female; Humans; Male; Nephrotic Syndrome; Thyroid Function Tests; Thyroid G

2011
[Relationship between serum thyroid hormone and GH-IGF axis, growth failure in nephrotic rats].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2001, Jun-28, Volume: 26, Issue:3

    Topics: Animals; Doxorubicin; Growth Disorders; Male; Nephrotic Syndrome; Random Allocation; Rats; Rats, Spr

2001
ASSESSMENT OF THYROID FUNCTION BY THE COMBINED USE OF THE SERUM PROTEIN-BOUND IODINE AND RESIN UPTAKE OF 131-I-TRIIODOTHYRONINE.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: Blood Proteins; Geriatrics; Hyperthyroidism; Hypothyroidism; Iodine; Iodine Isotopes; Nephrotic Synd

1965
[Clinical studies on protein and water metabolism by using isotopes. 2. Studies on the mechanism of action of anabolic steroids using 131-I-labeled human serum albumin].
    Nihon Naibunpi Gakkai zasshi, 1967, May-20, Volume: 43, Issue:2

    Topics: Addison Disease; Adolescent; Adult; Aged; Anorexia Nervosa; Body Weight; Child; Dexamethasone; Femal

1967
Biochemical hypothyroidism in Nigerian children with nephrotic syndrome.
    Annals of tropical paediatrics, 1983, Volume: 3, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Female; Humans; Hypothyroidism; Male; Nephrotic Syndrome; Niger

1983
Thyroid function in patients with proteinuria and normal or increased serum creatinine concentration.
    Acta endocrinologica, 1983, Volume: 102, Issue:3

    Topics: Aged; Creatinine; Female; Humans; Male; Middle Aged; Nephrotic Syndrome; Proteinuria; Thyroid Functi

1983
Differences in response of proteolytic activity in cardiac, skeletal and diaphragm muscles to hormones and catabolic conditions.
    Molecular and cellular endocrinology, 1980, Volume: 18, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Diaphragm; Fasting; Glucagon; Heart; Hormones; Male; Muscl

1980
Hypothyroidism in infants with nephrotic syndrome.
    Pediatric nephrology (Berlin, Germany), 1994, Volume: 8, Issue:6

    Topics: Biopsy; Child, Preschool; Creatinine; Female; Follow-Up Studies; Humans; Hypothyroidism; Infant; Inf

1994
Thyroid function in children with nephrotic syndrome.
    Pediatric nephrology (Berlin, Germany), 1994, Volume: 8, Issue:4

    Topics: Child; Child, Preschool; Female; Humans; Male; Nephrotic Syndrome; Radioimmunoassay; Thyroid Functio

1994
Hyperlipoproteinemia of aminonucleoside-induced nephrotic syndrome--modulation by glucocorticoids and triiodothyronine.
    Israel journal of medical sciences, 1996, Volume: 32, Issue:6

    Topics: Animals; Blood Proteins; Fatty Acids, Nonesterified; Glucocorticoids; Gluconeogenesis; Hyperlipoprot

1996
Regulation of hepatic angiotensinogen gene expression in nephrotic rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1997, Volume: 19, Issue:3

    Topics: Adrenalectomy; Angiotensinogen; Animals; Captopril; Dexamethasone; Ethinyl Estradiol; Gene Expressio

1997
Bilateral nephrectomy reverses hypothyroidism in congenital nephrotic syndrome.
    Pediatric nephrology (Berlin, Germany), 1999, Volume: 13, Issue:3

    Topics: Child; Child, Preschool; Female; Humans; Hypothyroidism; Kidney Transplantation; Male; Nephrectomy;

1999
Thyroid function studies in the nephrotic syndrome.
    Annals of internal medicine, 1979, Volume: 90, Issue:3

    Topics: Adult; Female; Humans; Male; Middle Aged; Nephrotic Syndrome; Thyroid Function Tests; Thyroid Hormon

1979
The practical use of thyroid function tests.
    American family physician, 1977, Volume: 16, Issue:3

    Topics: Female; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Nephrotic Syndrome; Pregnancy

1977
Can urinary thyroid hormone loss cause hypothyroidism?
    Lancet (London, England), 1991, Aug-24, Volume: 338, Issue:8765

    Topics: Aged; Female; Humans; Hypothyroidism; Male; Middle Aged; Nephrotic Syndrome; Proteinuria; Thyrotropi

1991
rT3 metabolism in patients with nephrotic syndrome and normal GFR compared with normal subjects.
    The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 1

    Topics: Adult; Female; Glomerular Filtration Rate; Humans; Kinetics; Male; Models, Biological; Nephrotic Syn

1991
Effect of prednison therapy on serum levels of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3), T3-binding capacity, basal TSH level and TSH response to thyreoliberin (TRH) in children.
    Experimental and clinical endocrinology, 1985, Volume: 85, Issue:2

    Topics: Child; Child, Preschool; Female; Humans; Hypothyroidism; Male; Nephrotic Syndrome; Prednisone; Throm

1985
[Comparison of Triosorb, T-3 and Tetrasorb T-4 and the clinical effectivity of the value of T-7].
    Horumon to rinsho. Clinical endocrinology, 1970, Volume: 18, Issue:11

    Topics: Female; Humans; Hyperthyroidism; Hypothyroidism; Nephrotic Syndrome; Pregnancy; Thyroid Function Tes

1970
[The determination of the "free thyroxine" index in internal diseases].
    Nuclear-Medizin, 1967, Jul-15, Volume: 6, Issue:2

    Topics: Diagnosis, Differential; Erythrocytes; Heart Diseases; Heart Failure; Humans; Hyperthyroidism; Hypot

1967
A modified method for estimation of free thyroxine level and its correlation with the classical thyroid function tests.
    Endokrinologie, 1969, Volume: 55, Issue:3

    Topics: Female; Goiter; Hepatomegaly; Humans; Hypothyroidism; Iodine Radioisotopes; Male; Nephrotic Syndrome

1969
Hepatic metabolic pathways and hormonal status in experimental nephrotic syndrome.
    Israel journal of medical sciences, 1972, Volume: 8, Issue:3

    Topics: Amino Acids; Animals; Blood Glucose; Carbon Isotopes; Fasting; Gluconeogenesis; Glycolysis; Insulin;

1972