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triiodothyronine and Muscular Dystrophy, Animal

triiodothyronine has been researched along with Muscular Dystrophy, Animal in 11 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Muscular Dystrophy, Animal: MUSCULAR DYSTROPHY that occurs in VERTEBRATE animals.

Research Excerpts

ExcerptRelevanceReference
" Serum T4 and T3 concentrations of mice were found to rise immediately before the onset of muscle necrosis in the mdx mouse, and induction of hypothyroidism by treatment of animals with propylthiouracil was found to delay the onset of muscle necrosis."7.70Effect of propylthiouracil-induced hypothyroidism on the onset of skeletal muscle necrosis in dystrophin-deficient mdx mice. ( Beckett, GJ; Catapano, M; Davis, A; Helliwell, TR; Jackson, MJ; McArdle, A, 1998)
" Serum T4 and T3 concentrations of mice were found to rise immediately before the onset of muscle necrosis in the mdx mouse, and induction of hypothyroidism by treatment of animals with propylthiouracil was found to delay the onset of muscle necrosis."3.70Effect of propylthiouracil-induced hypothyroidism on the onset of skeletal muscle necrosis in dystrophin-deficient mdx mice. ( Beckett, GJ; Catapano, M; Davis, A; Helliwell, TR; Jackson, MJ; McArdle, A, 1998)
"The effect of hyperthyroidism on muscle repair was examined in mdx and control mice injected with triiodothyronine (T3) for 4 weeks."3.69Hyperthyroidism impairs early repair in normal but not dystrophic mdx mouse tibialis anterior muscle. An in vivo study. ( Anderson, JE; McIntosh, LM; Pernitsky, AN, 1996)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's5 (45.45)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Singh, YN1
Gleysteen, AL1
Ganschow, SL1
Georgiev, P1
Watson, AY1
Radie, K1
McCarthy, M1
Larsen, PR1
Murphy, RA1
King, DB3
King, CR1
Jacaruso, RB1
Anderson, JE2
Liu, L1
Kardami, E1
Sabeur, K1
Entrikin, RK3
Pernitsky, AN1
McIntosh, LM1
McArdle, A1
Helliwell, TR1
Beckett, GJ1
Catapano, M1
Davis, A1
Jackson, MJ1
Kopecky, J1
Sigurdson, L1
Park, IR1
Himms-Hagen, J1
Larson, DB1

Other Studies

11 other studies available for triiodothyronine and Muscular Dystrophy, Animal

ArticleYear
5'-Deiodinase type 1 activity in liver and brain of the thyroxine-treated dystrophic hamster.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:6

    Topics: Animals; Brain; Cricetinae; Iodide Peroxidase; Liver; Male; Muscular Dystrophy, Animal; Thyroxine; T

2004
[Diagnostic value of radioisotope methods of studying the thyroid of sheep].
    Veterinarno-meditsinski nauki, 1984, Volume: 21, Issue:4

    Topics: Animals; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Muscular Dystrophy, Animal;

1984
Thyroxine reverses deficits of nerve growth factor and epidermal growth factor in submandibular glands of mice with muscular dystrophy.
    Endocrinology, 1982, Volume: 110, Issue:4

    Topics: Animals; Epidermal Growth Factor; Female; Male; Mice; Microscopy, Electron; Muscular Dystrophy, Anim

1982
Avian muscular dystrophy: thyroidal influence on pectoralis muscle growth and glucose-6-phosphate dehydrogenase activity.
    Life sciences, 1981, Feb-02, Volume: 28, Issue:5

    Topics: Animals; Chickens; DNA; Glucosephosphate Dehydrogenase; Hypertrophy; Muscular Dystrophy, Animal; Pec

1981
The effects of hyperthyroidism on muscular dystrophy in the mdx mouse: greater dystrophy in cardiac and soleus muscle.
    Muscle & nerve, 1994, Volume: 17, Issue:1

    Topics: Animals; Body Weight; Fibroblast Growth Factor 2; Fluorescent Antibody Technique; Heart; Hyperthyroi

1994
Differential effects of methimazole and dexamethasone in avian muscular dystrophy.
    Life sciences, 1993, Volume: 52, Issue:13

    Topics: Animals; Body Weight; Chickens; Corticosterone; Creatine Kinase; Dexamethasone; Male; Methimazole; M

1993
Hyperthyroidism impairs early repair in normal but not dystrophic mdx mouse tibialis anterior muscle. An in vivo study.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1996, Volume: 74, Issue:3

    Topics: Animals; Autoradiography; Hyperthyroidism; Mice; Mice, Inbred C57BL; Muscles; Muscular Dystrophy, An

1996
Effect of propylthiouracil-induced hypothyroidism on the onset of skeletal muscle necrosis in dystrophin-deficient mdx mice.
    Clinical science (London, England : 1979), 1998, Volume: 95, Issue:1

    Topics: Animals; Animals, Newborn; Antithyroid Agents; Body Weight; Disease Models, Animal; Dystrophin; Hypo

1998
Thyroidal involvement in the expression of avian muscular dystrophy.
    Life sciences, 1991, Volume: 48, Issue:9

    Topics: Animals; Body Weight; Chickens; Creatine Kinase; Dose-Response Relationship, Drug; Injections, Subcu

1991
Thyroxine 5'-deiodinase in brown adipose tissue of myopathic hamsters.
    The American journal of physiology, 1986, Volume: 251, Issue:1 Pt 1

    Topics: Acclimatization; Adipose Tissue, Brown; Animals; Body Temperature Regulation; Body Weight; Carrier P

1986
Avian muscular dystrophy: serum thyroid defect and limited improvement with methimazole and propylthiouracil.
    Experimental neurology, 1985, Volume: 87, Issue:2

    Topics: Animals; Chickens; Male; Methimazole; Muscular Dystrophy, Animal; Poultry; Propylthiouracil; Thyroxi

1985