Page last updated: 2024-11-08

triiodothyronine and Multiple Myeloma

triiodothyronine has been researched along with Multiple Myeloma in 6 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the prevalence of euthyroid hypertriiodothyroninemia and/or hyperthyroxinemia and its clinical characteristics in multiple myeloma (MM) patients."8.02The Prevalence of Euthyroid Hypertriiodothyroninemia in Newly Diagnosed Multiple Myeloma and its Clinical Characteristics. ( Chen, Z; Hu, Y; Liu, A; Pan, Q; Wang, G; Zhang, W; Zhang, Y, 2021)
"To evaluate the prevalence of euthyroid hypertriiodothyroninemia and/or hyperthyroxinemia and its clinical characteristics in multiple myeloma (MM) patients."4.02The Prevalence of Euthyroid Hypertriiodothyroninemia in Newly Diagnosed Multiple Myeloma and its Clinical Characteristics. ( Chen, Z; Hu, Y; Liu, A; Pan, Q; Wang, G; Zhang, W; Zhang, Y, 2021)
"This integrin is overexpressed in multiple myeloma (MM) and other cancers."1.40Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells. ( Ashur-Fabian, O; Baharal, T; Cohen, K; Davis, PJ; Ellis, M; Erez, D; Flint, N; Hercbergs, A; Shalev, S, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Pan, Q1
Zhang, Y1
Zhang, W1
Hu, Y1
Chen, Z1
Liu, A1
Wang, G1
Cohen, K3
Ellis, M3
Shinderman, E1
Khoury, S2
Davis, PJ3
Hercbergs, A3
Ashur-Fabian, O3
Flint, N1
Shalev, S1
Erez, D1
Baharal, T1
Cissewski, K1
Faix, JD1
Reinwein, D1
Moses, AC1
van Zaanen, HC1
Romijn, JA1
Sauerwein, HP1
Lokhorst, HM1
Warnaar, SO1
Aarden, LA1
Endert, E1
van Oers, MH1

Other Studies

6 other studies available for triiodothyronine and Multiple Myeloma

ArticleYear
The Prevalence of Euthyroid Hypertriiodothyroninemia in Newly Diagnosed Multiple Myeloma and its Clinical Characteristics.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2021, Volume: 27, Issue:3

    Topics: Humans; Multiple Myeloma; Prevalence; Thyrotropin; Thyroxine; Triiodothyronine

2021
Relevance of the thyroid hormones-αvβ3 pathway in primary myeloma bone marrow cells and to bortezomib action.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Bone Marrow Cell

2015
Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells.
    Oncotarget, 2014, Aug-15, Volume: 5, Issue:15

    Topics: Bortezomib; Cell Adhesion; Cell Movement; Cell Proliferation; Humans; Matrix Metalloproteinase 9; Mu

2014
Thyroid hormone is a MAPK-dependent growth factor for human myeloma cells acting via αvβ3 integrin.
    Molecular cancer research : MCR, 2011, Volume: 9, Issue:10

    Topics: Cell Growth Processes; Cell Line, Tumor; Humans; Integrin alphaVbeta3; Mitogen-Activated Protein Kin

2011
Factitious hyperthyroxinemia due to a monoclonal IgA in a case of multiple myeloma.
    Clinical chemistry, 1993, Volume: 39, Issue:8

    Topics: Antibodies, Monoclonal; False Positive Reactions; Female; Humans; Immunoelectrophoresis; Immunoglobu

1993
Modulation of chronic excessive interleukin-6 production in multiple myeloma does not affect thyroid hormone concentrations.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:11

    Topics: Aged; Animals; Antibodies, Monoclonal; Biological Assay; Female; Humans; Immunoglobulin G; Infusions

1997