Page last updated: 2024-11-08

triiodothyronine and Malnourishment

triiodothyronine has been researched along with Malnourishment in 17 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"Iodine deficiency goiter can develop in children on a restrictive diet and most have normal thyroid function."8.12Thyroid function tests of iodine deficiency goiter can mimic thyroid hormone resistance alpha. ( Quintos, JB; Sasidharan Pillai, S, 2022)
"Low triiodothyronine (T3) syndrome has recently been evaluated as a prognostic marker of acute heart failure (AHF)."7.96Relation of Low Triiodothyronine Syndrome Associated With Aging and Malnutrition to Adverse Outcome in Patients With Acute Heart Failure. ( Asai, K; Asano, K; Goda, H; Hata, N; Kiuchi, K; Kobayashi, N; Matsushita, M; Okajima, F; Okazaki, H; Shibata, Y; Shigihara, S; Shimizu, W; Shirakabe, A; Tani, K, 2020)
"We investigated the combined roles of a low-nutrition diet (low levels of protein, iodine, and selenium) and T-2 toxin in bone development and to establish an experimental animal model of Kashin-Beck disease (KBD) that reliably mimics the disease's pathological changes for further study of the pathogenesis and prevention of the disease."7.79An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. ( Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z, 2013)
"Little is known about the impact of low triiodothyronine (T3) levels on mortality in end-stage renal disease (ESRD) patients starting hemodialysis (HD) and whether this impact is mediated by malnutrition, inflammation, or cardiac dysfunction."7.79The impact of low triiodothyronine levels on mortality is mediated by malnutrition and cardiac dysfunction in incident hemodialysis patients. ( Doh, FM; Han, JH; Han, JS; Han, SH; Kang, SW; Kim, CH; Kim, EJ; Koo, HM; Lee, MJ; Oh, HJ; Yoo, TH, 2013)
" Pregnancy induces physiological changes in thyroid homeostasis that are influenced by the iodine status."7.76Parameters of thyroid function throughout and after pregnancy in an iodine-deficient population. ( Ares, S; Costeira, MJ; de Escobar, GM; Oliveira, P; Palha, JA; Roque, S, 2010)
"This study evaluates the efficacy and safety of oral triiodothyronine on time to extubation for infants less than 5 months undergoing heart surgery in Indonesia, and primarily relates to patients in emerging programs with high malnutrition and mortality."5.51Indonesian Study: Triiodothyronine for Infants Less than 5 Months Undergoing Cardiopulmonary Bypass. ( Fakhri, D; Haas, NA; Lopolisa, A; Marwali, EM; Portman, MA; Rayhan, M; Roebiono, PS; Sani, AA; Slee, A, 2022)
"Free triiodothyronine (FT3) is a marker of comorbidity in end-stage renal disease and in many acute and chronic diseases."5.40Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation. ( Altinoglu, A; Altunoglu, A; Arat, Z; Canoz, MB; Elsürer, R; Ozdemir, FN; Sezer, S; Yavuz, D; Yavuz, R, 2014)
"Iodine deficiency goiter can develop in children on a restrictive diet and most have normal thyroid function."4.12Thyroid function tests of iodine deficiency goiter can mimic thyroid hormone resistance alpha. ( Quintos, JB; Sasidharan Pillai, S, 2022)
"Low triiodothyronine (T3) syndrome has recently been evaluated as a prognostic marker of acute heart failure (AHF)."3.96Relation of Low Triiodothyronine Syndrome Associated With Aging and Malnutrition to Adverse Outcome in Patients With Acute Heart Failure. ( Asai, K; Asano, K; Goda, H; Hata, N; Kiuchi, K; Kobayashi, N; Matsushita, M; Okajima, F; Okazaki, H; Shibata, Y; Shigihara, S; Shimizu, W; Shirakabe, A; Tani, K, 2020)
"We investigated the combined roles of a low-nutrition diet (low levels of protein, iodine, and selenium) and T-2 toxin in bone development and to establish an experimental animal model of Kashin-Beck disease (KBD) that reliably mimics the disease's pathological changes for further study of the pathogenesis and prevention of the disease."3.79An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. ( Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z, 2013)
"Little is known about the impact of low triiodothyronine (T3) levels on mortality in end-stage renal disease (ESRD) patients starting hemodialysis (HD) and whether this impact is mediated by malnutrition, inflammation, or cardiac dysfunction."3.79The impact of low triiodothyronine levels on mortality is mediated by malnutrition and cardiac dysfunction in incident hemodialysis patients. ( Doh, FM; Han, JH; Han, JS; Han, SH; Kang, SW; Kim, CH; Kim, EJ; Koo, HM; Lee, MJ; Oh, HJ; Yoo, TH, 2013)
" Pregnancy induces physiological changes in thyroid homeostasis that are influenced by the iodine status."3.76Parameters of thyroid function throughout and after pregnancy in an iodine-deficient population. ( Ares, S; Costeira, MJ; de Escobar, GM; Oliveira, P; Palha, JA; Roque, S, 2010)
"This is called "low T3 syndrome", an adaptive metabolic mechanism to reduce energy expenditure and prevent catabolism."3.30Low T3 Syndrome on Admission and Response to Nutritional Support in Malnourished Medical Inpatients. ( Durmisi, M; Gressies, C; Kaegi-Braun, N; Mueller, B; Müller, NA; Schuetz, P; Stanga, Z; Tribolet, P, 2023)
"Free triiodothyronine (FT3) is a marker of comorbidity in end-stage renal disease and in many acute and chronic diseases."1.40Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation. ( Altinoglu, A; Altunoglu, A; Arat, Z; Canoz, MB; Elsürer, R; Ozdemir, FN; Sezer, S; Yavuz, D; Yavuz, R, 2014)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (17.65)29.6817
2010's9 (52.94)24.3611
2020's5 (29.41)2.80

Authors

AuthorsStudies
Marwali, EM1
Lopolisa, A1
Sani, AA1
Rayhan, M1
Roebiono, PS1
Fakhri, D1
Haas, NA1
Slee, A1
Portman, MA1
Sasidharan Pillai, S1
Quintos, JB1
Müller, NA1
Kaegi-Braun, N1
Durmisi, M1
Gressies, C1
Tribolet, P1
Stanga, Z1
Mueller, B1
Schuetz, P1
Asai, K1
Shirakabe, A1
Kiuchi, K1
Kobayashi, N1
Okazaki, H1
Matsushita, M1
Shibata, Y1
Goda, H1
Shigihara, S1
Asano, K1
Tani, K1
Okajima, F1
Hata, N1
Shimizu, W1
Stefanelli, S1
Michou, E1
Strebel, I1
Lopez-Ayala, P1
Mueller, C1
Mehus, AA1
Picklo, MJ1
Heikura, IA1
Uusitalo, ALT1
Stellingwerff, T1
Bergland, D1
Mero, AA1
Burke, LM1
Kang, P1
Yao, Y1
Yang, J1
Shen, B1
Zhou, Z1
Pei, F1
Koo, HM1
Kim, CH1
Doh, FM1
Lee, MJ1
Kim, EJ1
Han, JH1
Han, JS1
Oh, HJ1
Han, SH1
Yoo, TH1
Kang, SW1
Yavuz, D1
Sezer, S1
Yavuz, R1
Canoz, MB1
Altunoglu, A1
Altinoglu, A1
Elsürer, R1
Arat, Z1
Ozdemir, FN1
Florêncio, TM1
Bueno, NB1
Britto, RA1
Albuquerque, FC1
Lins, IL1
Sawaya, AL1
Fernández-Reyes, MJ1
Sánchez, R1
Heras, M1
Tajada, P1
Iglesias, P1
García, L1
García Arévalo, MC1
Molina, A1
Rodríguez, A1
Alvarez-Ude, F1
Costeira, MJ1
Oliveira, P1
Ares, S1
Roque, S1
de Escobar, GM2
Palha, JA1
Luca, F1
Goichot, B1
Brue, T1
Grazul-Bilska, AT1
Borowczyk, E1
Bilski, JJ1
Reynolds, LP1
Redmer, DA1
Caton, JS1
Vonnahme, KA1
Pedraza, PE1
Obregon, MJ1
Escobar-Morreale, HF1
del Rey, FE1
Toyoda, N1
Nomura, E1
Nishikawa, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tetronine (Sodium Liothyronine) for Infants & Children Undergoing Cardiopulmonary Bypass in a Middle Income Nation (OTICC Study)[NCT02222532]Phase 3224 participants (Actual)Interventional2013-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for triiodothyronine and Malnourishment

ArticleYear
[Non thyroidal illnesses (NTIS)].
    Annales d'endocrinologie, 2010, Volume: 71 Suppl 1

    Topics: Acute Disease; Chronic Disease; Cytokines; Euthyroid Sick Syndromes; Humans; Hydrocortisone; Iodide

2010
[Low T3 syndrome, low T4 syndrome (euthyroid sick syndrome)].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, May-28, Volume: Suppl 1

    Topics: Animals; Diabetes Complications; Diagnosis, Differential; Euthyroid Sick Syndromes; Humans; Liver Ci

2006

Trials

2 trials available for triiodothyronine and Malnourishment

ArticleYear
Indonesian Study: Triiodothyronine for Infants Less than 5 Months Undergoing Cardiopulmonary Bypass.
    Pediatric cardiology, 2022, Volume: 43, Issue:4

    Topics: Cardiac Output, Low; Cardiopulmonary Bypass; Double-Blind Method; Humans; Indonesia; Infant; Malnutr

2022
Low T3 Syndrome on Admission and Response to Nutritional Support in Malnourished Medical Inpatients.
    The Journal of clinical endocrinology and metabolism, 2023, 05-17, Volume: 108, Issue:6

    Topics: Adult; Euthyroid Sick Syndromes; Humans; Inpatients; Malnutrition; Nutritional Support; Triiodothyro

2023

Other Studies

13 other studies available for triiodothyronine and Malnourishment

ArticleYear
Thyroid function tests of iodine deficiency goiter can mimic thyroid hormone resistance alpha.
    Journal of pediatric endocrinology & metabolism : JPEM, 2022, Nov-25, Volume: 35, Issue:11

    Topics: Child; Female; Goiter; Goiter, Endemic; Humans; Hypothyroidism; Iodine; Malnutrition; Thyroglobulin;

2022
Relation of Low Triiodothyronine Syndrome Associated With Aging and Malnutrition to Adverse Outcome in Patients With Acute Heart Failure.
    The American journal of cardiology, 2020, 02-01, Volume: 125, Issue:3

    Topics: Acute Disease; Aged; Aged, 80 and over; Biomarkers; Cause of Death; Female; Follow-Up Studies; Heart

2020
Reader's Comment on "Relation of Low Triiodothyronine Syndrome Associated With Aging and Malnutrition to Adverse Outcome in Patients With Acute Heart Failure".
    The American journal of cardiology, 2020, 07-01, Volume: 126

    Topics: Aging; Euthyroid Sick Syndromes; Heart Failure; Humans; Malnutrition; Triiodothyronine

2020
Brain and Hepatic Mt mRNA Is Reduced in Response to Mild Energy Restriction and n-3 Polyunsaturated Fatty Acid Deficiency in Juvenile Rats.
    Nutrients, 2017, Oct-19, Volume: 9, Issue:10

    Topics: alpha-Linolenic Acid; Animals; Body Composition; Brain; Caloric Restriction; Copper; Corn Oil; Corti

2017
Low Energy Availability Is Difficult to Assess but Outcomes Have Large Impact on Bone Injury Rates in Elite Distance Athletes.
    International journal of sport nutrition and exercise metabolism, 2018, Jul-01, Volume: 28, Issue:4

    Topics: Adult; Amenorrhea; Athletes; Athletic Injuries; Bone and Bones; Bone Density; Cross-Sectional Studie

2018
An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin.
    Osteoarthritis and cartilage, 2013, Volume: 21, Issue:8

    Topics: Animal Nutritional Physiological Phenomena; Animals; Cartilage, Articular; Chondrocytes; Dietary Pro

2013
The impact of low triiodothyronine levels on mortality is mediated by malnutrition and cardiac dysfunction in incident hemodialysis patients.
    European journal of endocrinology, 2013, Volume: 169, Issue:4

    Topics: Adult; Aged; Echocardiography; Female; Heart Diseases; Humans; Incidence; Inflammation; Kaplan-Meier

2013
Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation.
    Iranian journal of kidney diseases, 2014, Volume: 8, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Female; Humans; Inflamm

2014
Waist-to-Height Gain and Triiodothyronine Concentrations in a Cohort of Socially Vulnerable Short-Stature Women: A Four-Year Follow-Up Study.
    Annals of nutrition & metabolism, 2016, Volume: 68, Issue:4

    Topics: Adult; Body Mass Index; Brazil; Cohort Studies; Comorbidity; Female; Growth Disorders; Humans; Hypot

2016
[Can FT3 levels facilitate the detection of inflammation or catabolism and malnutrition in dialysis patients?].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2009, Volume: 29, Issue:4

    Topics: Aged; Cross-Sectional Studies; Female; Humans; Inflammation; Male; Malnutrition; Renal Dialysis; Tri

2009
Parameters of thyroid function throughout and after pregnancy in an iodine-deficient population.
    Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:9

    Topics: Adult; Female; Humans; Iodine; Longitudinal Studies; Malnutrition; Pregnancy; Thyroglobulin; Thyroid

2010
Overfeeding and underfeeding have detrimental effects on oocyte quality measured by in vitro fertilization and early embryonic development in sheep.
    Domestic animal endocrinology, 2012, Volume: 43, Issue:4

    Topics: Animals; Blastocyst; Body Composition; Body Weight; Embryo Culture Techniques; Embryonic Development

2012
Mechanisms of adaptation to iodine deficiency in rats: thyroid status is tissue specific. Its relevance for man.
    Endocrinology, 2006, Volume: 147, Issue:5

    Topics: Analysis of Variance; Animals; Body Weight; Female; Humans; Iodide Peroxidase; Iodine; Iodine Radioi

2006