Page last updated: 2024-11-08

triiodothyronine and Lymphoma

triiodothyronine has been researched along with Lymphoma in 13 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.

Research Excerpts

ExcerptRelevanceReference
"When the lymphoma was in remission, her circulating T3 concentration was 2-55 nmol/l but when it relapsed it fell to 0-55 nmol/l."5.26Inhibition of conversion of thyroxine to triiodothyronine in patients with severe chronic illness. ( Carter, JN; Corcoran, JM; Eastmen, CJ; Lazarus, L, 1976)
" A cytotoxic effect of this system on a line of mouse ascitic lymphoma cells (LSTRA) is demonstrated here using four different assay systems: 51Cr release, trypan blue exclusion, inhibition of glucose C-1 oxidation, and loss of oncogenicity for mice."3.65Peroxidase-H2O2-halide system: Cytotoxic effect on mammalian tumor cells. ( Clark, RA; Einstein, AB; Fefer, A; Klebanoff, SJ, 1975)
"Children with cancer were also evaluated after antineoplasic treatment (CAT, n = 17)."1.38Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment. ( Brito, CX; Guerra, RN; Liberio, SA; Lima, MV; Mendonça, C; Mouchrek-Filho, JC; Nascimento, FR; Oliveira-Junior, JJ; Paim, DB; Pereira, AL, 2012)
"Whenever thyroid lymphoma is suspected, we recommend an ultrasound scan of the thyroid gland and fine needle aspiration biopsy as initial diagnostic procedures."1.29Clinical aspects of primary thyroid lymphoma: diagnosis and treatment based on our experience of 119 cases. ( Ikeda, H; Katayama, S; Kuma, K; Matsuzuka, F; Miyauchi, A; Narabayashi, I; Sugawara, M, 1993)
"The mean thyroid dose for irradiated malignant lymphomas in the prospective and the retrospective group was 45 Gy and 43 Gy respectively."1.28Incidence of hypothyroidism after irradiation of the neck with special reference to lymphoma patients. A retrospective and prospective analysis. ( Becker, W; Feyerabend, T; Kapp, B; Reiners, C; Richter, E, 1990)
"When the lymphoma was in remission, her circulating T3 concentration was 2-55 nmol/l but when it relapsed it fell to 0-55 nmol/l."1.26Inhibition of conversion of thyroxine to triiodothyronine in patients with severe chronic illness. ( Carter, JN; Corcoran, JM; Eastmen, CJ; Lazarus, L, 1976)
"The non-surgical treatment of thyroid cancer is outlined."1.25The non-surgical treatment of thyroid cancer. ( Halnan, KE, 1975)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's5 (38.46)18.2507
2000's0 (0.00)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guerra, RN1
Oliveira-Junior, JJ1
Mouchrek-Filho, JC1
Liberio, SA1
Lima, MV1
Paim, DB1
Brito, CX1
Mendonça, C1
Nascimento, FR1
Pereira, AL1
NIELSEN, PE1
RANLOV, P1
Matsuzuka, F1
Miyauchi, A1
Katayama, S1
Narabayashi, I1
Ikeda, H1
Kuma, K1
Sugawara, M1
Fletcher-Chiappini, SE1
Compton, MM1
LaVoie, HA1
Day, EB1
Witorsch, RJ1
Comptom, MM1
Nakanishi, K1
Taniguchi, Y1
Onji, M1
Worm, AM2
Brinckmeyer, LM2
Nissen, NI2
Halnan, KE1
Carter, JN1
Eastmen, CJ1
Corcoran, JM1
Lazarus, L1
Clark, RA1
Klebanoff, SJ1
Einstein, AB1
Fefer, A1
Feyerabend, T1
Kapp, B1
Richter, E1
Becker, W1
Reiners, C1
Hershman, JM1
Eriksen, E1
Kaufman, N1
Champlin, RE1
Kirkegaard, C1
Hasselbalch, H1
Faber, J1
Poulsen, S1
Bregengård, C1
Hasselstrøm, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Critical Illness Stress-induced Immune Suppression Prevention Trial[NCT00395161]Phase 3293 participants (Actual)Interventional2007-04-30Terminated (stopped due to Terminated for futility on 11/30/09 based on the recommendation of the DSMB)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

All-cause 28-day Mortality Rate.

(NCT00395161)
Timeframe: 28 days after admission to the PICU

Interventionparticipants (Number)
Enteral Zinc, Selenium, Glutamine, and IV Metoclopramide15
Enteral Whey Protein, IV Saline8

Antibiotic-free Days

(NCT00395161)
Timeframe: 48 hours after admission until PICU discharge

InterventionDays (Median)
Enteral Zinc, Selenium, Glutamine, and IV Metoclopramide1
Enteral Whey Protein, IV Saline2

Incidence of Prolonged Lymphopenia (Absolute Lymphocyte Count Less Than or Equal to 1,000/mm³ for > or Equal to 7 Days)

What is reported is the number of participants with counts qualifying as lymphopenia. (NCT00395161)
Timeframe: from time of PICU admission till discharge from PICU

Interventionparticipants (Number)
Enteral Zinc, Selenium, Glutamine, and IV Metoclopramide5
Enteral Whey Protein, IV Saline12

Rate of Nosocomial Infection or Clinical Sepsis Per 100 Study Days

(NCT00395161)
Timeframe: 48 hours after PICU admission till discharge from PICU

InterventionMean number of events per 100 study days (Mean)
Daily Nutriceutical Supplementation4.99
Whey Protein4.83

The Primary Endpoint of This Study is the Median Time Between Admission to the PICU and Occurrence of Nosocomial Infection or Clinical Sepsis in PICU Patients Who Have Endotracheal Tubes, Central Venous Catheters, or Urinary Catheters.

(NCT00395161)
Timeframe: 48 hours after admission until 5 days after discharged from the PICU

InterventionDays (Median)
Daily Nutriceutical Supplementation12.1
Whey Protein13.2

Reviews

1 review available for triiodothyronine and Lymphoma

ArticleYear
MYXOEDEMA COMA. TWO CASE REPORTS AND A REVIEW.
    Acta endocrinologica, 1964, Volume: 45

    Topics: Autoimmune Diseases; Coma; Geriatrics; Humans; Hydrocortisone; Hyponatremia; Hypothermia; Hypothermi

1964

Other Studies

12 other studies available for triiodothyronine and Lymphoma

ArticleYear
Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2012, Volume: 41, Issue:7

    Topics: Biomarkers; Blood Glucose; Case-Control Studies; Central Nervous System Neoplasms; Child; Cohort Stu

2012
Clinical aspects of primary thyroid lymphoma: diagnosis and treatment based on our experience of 119 cases.
    Thyroid : official journal of the American Thyroid Association, 1993,Summer, Volume: 3, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Cycl

1993
Glucocorticoid-prolactin interactions in Nb2 lymphoma cells: antiproliferative versus anticytolytic effects.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1993, Volume: 202, Issue:3

    Topics: Analysis of Variance; Animals; Cell Division; Cell Survival; Dexamethasone; DNA Damage; Dose-Respons

1993
Triiodothyronine enhances expression of the interleukin-2 receptor alpha chain.
    Endocrine journal, 1999, Volume: 46, Issue:3

    Topics: Cells, Cultured; Colforsin; Concanavalin A; Gene Expression; Humans; Killer Cells, Natural; Leukocyt

1999
[Thyroid function in malignant lymphoma].
    Ugeskrift for laeger, 1977, Sep-05, Volume: 139, Issue:36

    Topics: Adult; Aged; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, N

1977
Thyroid function in malignant lymphoma.
    Acta medica Scandinavica, 1977, Volume: 202, Issue:6

    Topics: Adolescent; Adult; Aged; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse;

1977
The non-surgical treatment of thyroid cancer.
    The British journal of surgery, 1975, Volume: 62, Issue:10

    Topics: Adenocarcinoma; Age Factors; Aged; Calcitonin; Carcinoma, Papillary; Cell Count; Cell Survival; Chil

1975
Inhibition of conversion of thyroxine to triiodothyronine in patients with severe chronic illness.
    Clinical endocrinology, 1976, Volume: 5, Issue:6

    Topics: Chronic Disease; Humans; Lymphoma; Myocardial Infarction; Thyrotropin; Thyroxine; Triiodothyronine

1976
Peroxidase-H2O2-halide system: Cytotoxic effect on mammalian tumor cells.
    Blood, 1975, Volume: 45, Issue:2

    Topics: Animals; Ascitic Fluid; Carbon Dioxide; Carbon Radioisotopes; Carcinogens; Chromium Radioisotopes; F

1975
Incidence of hypothyroidism after irradiation of the neck with special reference to lymphoma patients. A retrospective and prospective analysis.
    Acta oncologica (Stockholm, Sweden), 1990, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hypothyr

1990
Thyroid function tests in patients undergoing bone marrow transplantation.
    Bone marrow transplantation, 1990, Volume: 6, Issue:1

    Topics: Adult; Anemia, Aplastic; Bone Marrow Transplantation; Female; Humans; Leukemia; Lymphoma; Male; Thyr

1990
Thyroid hormone metabolism in hypermetabolic patients with haematological disorders.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989, Volume: 21, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Female; Hematologic Diseases; Humans; Leukemia; Lymphoma; Male; Midd

1989