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triiodothyronine and Left Ventricular Dysfunction

triiodothyronine has been researched along with Left Ventricular Dysfunction in 20 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone-induced thyrotoxicosis (AIT) is a challenging management problem, since patients treated with amiodarone invariably have underlying heart disease."7.73Amiodarone-induced thyrotoxicosis: left ventricular dysfunction is associated with increased mortality. ( Diamond, T; Lewis, M; O'Sullivan, AJ, 2006)
"Hypothyroidism was defined as serum thyroid-stimulating hormone (TSH) > 4."6.41Thyroid hormone metabolism in patients with congestive heart failure: the low triiodothyronine state. ( Ascheim, DD; Hryniewicz, K, 2002)
"Recent data suggest that low triiodothyronine (T3) syndrome may contribute to the pathophysiology of cardiac diseases."3.75[Low T3 syndrome and left ventricular diastolic function]. ( Bianchi, M; Bindi, M; Cassetti, G; Castiglioni, M; Pinelli, M, 2009)
"Patients with congestive heart failure (CHF) often have low serum triiodothyronine (T(3)) concentrations."3.75Physiological replacement of T3 improves left ventricular function in an animal model of myocardial infarction-induced congestive heart failure. ( Danzi, S; Henderson, KK; Klein, I; Leya, G; Paul, JT; Samarel, AM, 2009)
"Amiodarone-induced thyrotoxicosis (AIT) is a challenging management problem, since patients treated with amiodarone invariably have underlying heart disease."3.73Amiodarone-induced thyrotoxicosis: left ventricular dysfunction is associated with increased mortality. ( Diamond, T; Lewis, M; O'Sullivan, AJ, 2006)
"Low triiodothyronine is associated with left ventricular dysfunction and left ventricular hypertrophy in ESRD patients."3.73Low triiodothyronine and cardiomyopathy in patients with end-stage renal disease. ( Benedetto, F; Bonanno, G; Cutrupi, S; Malatino, LS; Mallamaci, F; Pizzini, P; Seminara, G; Tripepi, G; Zoccali, C, 2006)
"To study the relationship between the TCM Syndrome Differentiation-types of congestive heart failure (CHF) and thyroid hormones, including triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH), and atrial natriuretic peptide (ANP), as well as cardiac function parameters, including left ventricular ejection fraction (LVEF), mean velocity of circumferentid fiber shortening (mVcf) and A peak/E peak (A/E)."3.72[Study on relationship among thyroid hormone relativity and Syndrome Differentiation-types of TCM in patients with congestive heart failure]. ( Chen, J; Cheng, X; Gao, XL; Huang, S; Huang, T; Pei, Y; Sheng, L; Shi, D; Wang, L; Yan, X; Yang, A; Zhang, BZ; Zhou, J, 2004)
"Hypothyroidism was defined as serum thyroid-stimulating hormone (TSH) > 4."2.41Thyroid hormone metabolism in patients with congestive heart failure: the low triiodothyronine state. ( Ascheim, DD; Hryniewicz, K, 2002)
"How the duration of hypothyroidism affects left ventricular diastolic function is not well-characterized."1.37Acute and chronic hypothyroidism are associated with similar left ventricular diastolic dysfunction relative to the euthyroid state: results of doppler echocardiographic comparisons. ( Benchuga, G; Gauna, A; Marlowe, RJ; Messuti, H; Papadopulos, G; Silva Croome, MC; Viale, F, 2011)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.00)18.2507
2000's10 (50.00)29.6817
2010's7 (35.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Bogush, N1
Tan, L1
Naqvi, E1
Calvert, JW1
Graham, RM1
Taylor, WR1
Naqvi, N1
Husain, A1
Weltman, NY1
Pol, CJ1
Zhang, Y1
Wang, Y1
Koder, A1
Raza, S1
Zucchi, R1
Saba, A1
Colligiani, D1
Gerdes, AM1
Jankauskienė, E2
Orda, P2
Rumbinaitė, E1
Žaliaduonytė-Pekšienė, D1
Steponavičiutė, R1
Krasauskienė, A1
Vaškelytė, JJ2
Bunevičius, R2
Madan, N1
Tiwari, N1
Stampfer, M1
Schubart, U1
Barauskienė, G1
Mickuvienė, N1
Brožaitienė, J1
Cassetti, G1
Pinelli, M1
Bindi, M1
Bianchi, M1
Castiglioni, M1
Henderson, KK1
Danzi, S2
Paul, JT1
Leya, G1
Klein, I3
Samarel, AM1
Lubrano, V1
Pingitore, A2
Carpi, A1
Iervasi, G2
Gauna, A1
Messuti, H1
Papadopulos, G1
Benchuga, G1
Viale, F1
Marlowe, RJ1
Silva Croome, MC1
Selvaraj, S1
Akhter, N1
Bonow, RO1
Shah, SJ1
Ascheim, DD1
Hryniewicz, K1
Sirlak, M1
Yazicioglu, L1
Inan, MB1
Eryilmaz, S1
Tasoz, R1
Aral, A1
Ozyurda, U1
Zhou, J1
Gao, XL1
Zhang, BZ1
Huang, S1
Wang, L1
Sheng, L1
Shi, D1
Yan, X1
Yang, A1
Huang, T1
Pei, Y1
Chen, J1
Cheng, X1
Mishra, TK1
Routray, SN1
Das, S1
Behera, M1
O'Sullivan, AJ1
Lewis, M1
Diamond, T1
Barison, A1
Prontera, C1
Pratali, L1
Emdin, M1
Giannessi, D1
Neglia, D1
Zoccali, C1
Benedetto, F1
Mallamaci, F1
Tripepi, G1
Cutrupi, S1
Pizzini, P1
Malatino, LS1
Bonanno, G1
Seminara, G1
Klemperer, JD1
Gomez, M1
Helm, RE1
Ojamaa, K1
Thomas, SJ1
Isom, OW1
Krieger, K1
Spinale, FG1
Ducart, A1

Reviews

3 reviews available for triiodothyronine and Left Ventricular Dysfunction

ArticleYear
Thyroid hormone metabolism in patients with congestive heart failure: the low triiodothyronine state.
    Thyroid : official journal of the American Thyroid Association, 2002, Volume: 12, Issue:6

    Topics: Adult; Aged; Cohort Studies; Female; Heart Failure; Humans; Hypothyroidism; Male; Middle Aged; Preva

2002
Cellular and molecular therapeutic targets for treatment of contractile dysfunction after cardioplegic arrest.
    The Annals of thoracic surgery, 1999, Volume: 68, Issue:5

    Topics: Adenosine; Adenosine Triphosphate; Animals; Cardioplegic Solutions; Cells, Cultured; Heart Arrest, I

1999
Interactions between inotropic drugs.
    Acta anaesthesiologica Belgica, 2001, Volume: 52, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Agonists; Calcium; Cardiotonic Agents; Cyclic N

2001

Trials

2 trials available for triiodothyronine and Left Ventricular Dysfunction

ArticleYear
Oral thyroid hormone pretreatment in left ventricular dysfunction.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2004, Volume: 26, Issue:4

    Topics: Administration, Oral; Aged; Cardiac Output; Cardiotonic Agents; Central Venous Pressure; Coronary Ar

2004
Thyroid hormone treatment after coronary-artery bypass surgery.
    The New England journal of medicine, 1995, Dec-07, Volume: 333, Issue:23

    Topics: Aged; Coronary Artery Bypass; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Pos

1995

Other Studies

15 other studies available for triiodothyronine and Left Ventricular Dysfunction

ArticleYear
Remuscularization with triiodothyronine and β
    Scientific reports, 2022, 05-25, Volume: 12, Issue:1

    Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Metoprolol; Mice; Myocardial Infarction; Myocardium

2022
Long-term physiological T3 supplementation in hypertensive heart disease in rats.
    American journal of physiology. Heart and circulatory physiology, 2015, Sep-15, Volume: 309, Issue:6

    Topics: Animals; Collagen; Female; Heart; Heart Failure; Heart Ventricles; Hypertension; Hypothyroidism; Myo

2015
Left ventricular function by speckle-tracking echocardiography in patients with low-T3 syndrome and acute myocardial infarction.
    Medicina (Kaunas, Lithuania), 2015, Volume: 51, Issue:4

    Topics: Aged; Diastole; Echocardiography; Euthyroid Sick Syndromes; Humans; Middle Aged; Myocardial Infarcti

2015
Hypothyroid heart: myxoedema as a cause of reversible dilated cardiomyopathy.
    BMJ case reports, 2015, Oct-14, Volume: 2015

    Topics: Cardiomyopathy, Dilated; Female; Heart; Humans; Hypothyroidism; Middle Aged; Myxedema; Thyroxine; Tr

2015
Relationship between left ventricular mechanics and low free triiodothyronine levels after myocardial infarction: a prospective study.
    Internal and emergency medicine, 2016, Volume: 11, Issue:3

    Topics: Area Under Curve; Biomarkers; Cohort Studies; Echocardiography; Female; Follow-Up Studies; Hospitals

2016
[Low T3 syndrome and left ventricular diastolic function].
    Giornale italiano di cardiologia (2006), 2009, Volume: 10, Issue:8

    Topics: Aged; Biomarkers; Case-Control Studies; Diastole; Echocardiography, Doppler; Euthyroid Sick Syndrome

2009
Physiological replacement of T3 improves left ventricular function in an animal model of myocardial infarction-induced congestive heart failure.
    Circulation. Heart failure, 2009, Volume: 2, Issue:3

    Topics: Animals; Blood Pressure; Diastole; Disease Models, Animal; Gene Expression Regulation; Heart Failure

2009
Relationship between triiodothyronine and proinflammatory cytokines in chronic heart failure.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:3

    Topics: Adult; Aged; C-Reactive Protein; Disease Progression; Female; Heart Failure; Humans; Inflammation; I

2010
Acute and chronic hypothyroidism are associated with similar left ventricular diastolic dysfunction relative to the euthyroid state: results of doppler echocardiographic comparisons.
    Journal of endocrinological investigation, 2011, Volume: 34, Issue:9

    Topics: Acute Disease; Adult; Chronic Disease; Diastole; Echocardiography, Doppler; Female; Humans; Hypothyr

2011
Association of serum triiodothyronine with B-type natriuretic peptide and severe left ventricular diastolic dysfunction in heart failure with preserved ejection fraction.
    The American journal of cardiology, 2012, Jul-15, Volume: 110, Issue:2

    Topics: Age Factors; Aged; Blood Pressure; Diabetes Mellitus; Diastole; Echocardiography; Female; Heart Fail

2012
[Study on relationship among thyroid hormone relativity and Syndrome Differentiation-types of TCM in patients with congestive heart failure].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2004, Volume: 24, Issue:10

    Topics: Adult; Aged; Atrial Natriuretic Factor; Diagnosis, Differential; Female; Heart Failure; Humans; Male

2004
Left ventricular dysfunction in patients with subclinical hypothyroidism and its reversibility after hormone therapy.
    The Journal of the Association of Physicians of India, 2005, Volume: 53

    Topics: Adult; Case-Control Studies; Diastole; Female; Hormone Replacement Therapy; Humans; Hypothyroidism;

2005
Amiodarone-induced thyrotoxicosis: left ventricular dysfunction is associated with increased mortality.
    European journal of endocrinology, 2006, Volume: 154, Issue:4

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Female; Goiter, Nodular; Graves Disease; Humans; Male

2006
Early activation of an altered thyroid hormone profile in asymptomatic or mildly symptomatic idiopathic left ventricular dysfunction.
    Journal of cardiac failure, 2006, Volume: 12, Issue:7

    Topics: Aged; Cardiac Output, Low; Female; Hormones; Humans; Inflammation; Interleukin-6; Male; Middle Aged;

2006
Low triiodothyronine and cardiomyopathy in patients with end-stage renal disease.
    Journal of hypertension, 2006, Volume: 24, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Case-Control Studies; Female; Humans; Hypertroph

2006