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triiodothyronine and Leber Congenital Amaurosis

triiodothyronine has been researched along with Leber Congenital Amaurosis in 1 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Leber Congenital Amaurosis: A rare degenerative inherited eye disease that appears at birth or in the first few months of life that results in a loss of vision. Not to be confused with LEBER HEREDITARY OPTIC NEUROPATHY, the disease is thought to be caused by abnormal development of PHOTORECEPTOR CELLS in the RETINA, or by the extremely premature degeneration of retinal cells.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ma, H1
Thapa, A1
Morris, L1
Redmond, TM1
Baehr, W1
Ding, XQ1

Other Studies

1 other study available for triiodothyronine and Leber Congenital Amaurosis

ArticleYear
Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Mar-04, Volume: 111, Issue:9

    Topics: Animals; Antithyroid Agents; cis-trans-Isomerases; Color Vision Defects; Cone Opsins; Cyclic Nucleot

2014