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triiodothyronine and Klinefelter Syndrome

triiodothyronine has been researched along with Klinefelter Syndrome in 5 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Klinefelter Syndrome: A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).

Research Excerpts

ExcerptRelevanceReference
"Klinefelter syndrome has been associated with thyroid abnormalities, the genesis of which is not yet fully clear."1.46A combined form of hypothyroidism in pubertal patients with non-mosaic Klinefelter syndrome. ( Anzuini, A; Granato, S; Lenzi, A; Panimolle, F; Radicioni, AF; Ruga, G; Spaziani, M; Tahani, N, 2017)
"In eleven patients with Klinefelter's Syndrome TSH, T4 and T3 levels have been measured after stimulation with TRH."1.26Response to thyrotrophin releasing hormone in Klinefelter's syndrome. ( Fyffe, JA; Lidgard, GP; Price, WH; Renton, WB; Yap, PL, 1978)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tahani, N1
Ruga, G1
Granato, S1
Spaziani, M1
Panimolle, F1
Anzuini, A1
Lenzi, A1
Radicioni, AF1
Bjørn, AM1
Bojesen, A1
Gravholt, CH1
Laurberg, P1
Smals, AG1
Kloppenborg, PW1
Lequin, RL1
Beex, L1
Ross, A1
Benraad, TJ1
Yap, PL1
Renton, WB1
Price, WH1
Fyffe, JA1
Lidgard, GP1
Carfagna, M1
Krans, HM1
Volkers, WS1

Other Studies

5 other studies available for triiodothyronine and Klinefelter Syndrome

ArticleYear
A combined form of hypothyroidism in pubertal patients with non-mosaic Klinefelter syndrome.
    Endocrine, 2017, Volume: 55, Issue:2

    Topics: Adolescent; Child; Humans; Hypothyroidism; Klinefelter Syndrome; Male; Puberty; Thyroid Function Tes

2017
Hypothyroidism secondary to hypothalamic-pituitary dysfunction may be part of the phenotype in klinefelter syndrome: a case-control study.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:7

    Topics: Adult; Autoantibodies; Case-Control Studies; Hormone Replacement Therapy; Humans; Hypothalamic Disea

2009
The pituitary-thyroid axis in Klinefelter's syndrome.
    Acta endocrinologica, 1977, Volume: 84, Issue:1

    Topics: Adult; Humans; Klinefelter Syndrome; Male; Pituitary Gland; Pituitary Gland, Anterior; Secretory Rat

1977
Response to thyrotrophin releasing hormone in Klinefelter's syndrome.
    Clinical endocrinology, 1978, Volume: 8, Issue:3

    Topics: Adult; Aged; Humans; Klinefelter Syndrome; Male; Middle Aged; Thyrotropin; Thyrotropin-Releasing Hor

1978
Studies on the heritability of the variation in TBG-activity as reflected in the resin uptake of 131 I-T 3 in humans.
    Acta endocrinologica, 1972, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Chromosomes; Female; Genetics, Medical; Genotype; Human

1972