triiodothyronine has been researched along with Klinefelter Syndrome in 5 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Klinefelter Syndrome: A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).
Excerpt | Relevance | Reference |
---|---|---|
"Klinefelter syndrome has been associated with thyroid abnormalities, the genesis of which is not yet fully clear." | 1.46 | A combined form of hypothyroidism in pubertal patients with non-mosaic Klinefelter syndrome. ( Anzuini, A; Granato, S; Lenzi, A; Panimolle, F; Radicioni, AF; Ruga, G; Spaziani, M; Tahani, N, 2017) |
"In eleven patients with Klinefelter's Syndrome TSH, T4 and T3 levels have been measured after stimulation with TRH." | 1.26 | Response to thyrotrophin releasing hormone in Klinefelter's syndrome. ( Fyffe, JA; Lidgard, GP; Price, WH; Renton, WB; Yap, PL, 1978) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (60.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Tahani, N | 1 |
Ruga, G | 1 |
Granato, S | 1 |
Spaziani, M | 1 |
Panimolle, F | 1 |
Anzuini, A | 1 |
Lenzi, A | 1 |
Radicioni, AF | 1 |
Bjørn, AM | 1 |
Bojesen, A | 1 |
Gravholt, CH | 1 |
Laurberg, P | 1 |
Smals, AG | 1 |
Kloppenborg, PW | 1 |
Lequin, RL | 1 |
Beex, L | 1 |
Ross, A | 1 |
Benraad, TJ | 1 |
Yap, PL | 1 |
Renton, WB | 1 |
Price, WH | 1 |
Fyffe, JA | 1 |
Lidgard, GP | 1 |
Carfagna, M | 1 |
Krans, HM | 1 |
Volkers, WS | 1 |
5 other studies available for triiodothyronine and Klinefelter Syndrome
Article | Year |
---|---|
A combined form of hypothyroidism in pubertal patients with non-mosaic Klinefelter syndrome.
Topics: Adolescent; Child; Humans; Hypothyroidism; Klinefelter Syndrome; Male; Puberty; Thyroid Function Tes | 2017 |
Hypothyroidism secondary to hypothalamic-pituitary dysfunction may be part of the phenotype in klinefelter syndrome: a case-control study.
Topics: Adult; Autoantibodies; Case-Control Studies; Hormone Replacement Therapy; Humans; Hypothalamic Disea | 2009 |
The pituitary-thyroid axis in Klinefelter's syndrome.
Topics: Adult; Humans; Klinefelter Syndrome; Male; Pituitary Gland; Pituitary Gland, Anterior; Secretory Rat | 1977 |
Response to thyrotrophin releasing hormone in Klinefelter's syndrome.
Topics: Adult; Aged; Humans; Klinefelter Syndrome; Male; Middle Aged; Thyrotropin; Thyrotropin-Releasing Hor | 1978 |
Studies on the heritability of the variation in TBG-activity as reflected in the resin uptake of 131 I-T 3 in humans.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Chromosomes; Female; Genetics, Medical; Genotype; Human | 1972 |