Page last updated: 2024-11-08

triiodothyronine and Kidney Failure

triiodothyronine has been researched along with Kidney Failure in 11 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.

Research Excerpts

ExcerptRelevanceReference
"We performed a methodological comparison of free triiodothyronine (FT3) estimates in patients with liver cirrhosis and renal failure."3.69Determination of free triiodothyronine by six different methods in patients with non-thyroidal illness and in patients treated with amiodarone. ( Chambron, J; Christofides, N; Gasser, F; Gervais, A; Kaltenbach, G; Petitjean, P; Roul, G; Sapin, R; Schlienger, JL, 1995)
" This case illustrates the potential for hypothyroid-induced renal dysfunction to lead to adverse clinical consequences in patients taking medications cleared by the kidneys."1.35Lithium toxicity precipitated by profound hypothyroidism. ( Gohh, R; Gopalakrishnan, G; Hennessey, JV; Phillips, BD, 2008)
"In chronic renal failure (CRF), dietary protein is one of the factors that deteriorates residual renal functions."1.33Increased protein level of PEPT1 intestinal H+-peptide cotransporter upregulates absorption of glycylsarcosine and ceftibuten in 5/6 nephrectomized rats. ( Inui, K; Ji, L; Masuda, S; Nishihara, K; Okuda, M; Shimizu, Y, 2005)
"The effect of ischemia induced acute renal failure (ARF) on the transport of phosphate (Pi) after early (15-30 min) and prolonged (60 min) ischemia in the brush border membrane vesicles (BBMV) from rat renal cortex was studied."1.33Effect of ischemia reperfusion on sodium-dependent phosphate transport in renal brush border membranes. ( Asghar, M; Banday, AA; Khan, F; Khundmiri, SJ; Levi, M; Salim, S; Yusufi, AN, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's1 (9.09)18.2507
2000's7 (63.64)29.6817
2010's0 (0.00)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Mikkaichi, T1
Suzuki, T1
Onogawa, T1
Tanemoto, M1
Mizutamari, H1
Okada, M1
Chaki, T1
Masuda, S2
Tokui, T1
Eto, N1
Abe, M1
Satoh, F1
Unno, M1
Hishinuma, T1
Inui, K2
Ito, S1
Goto, J1
Abe, T1
Peters, J1
Roumeliotis, S1
Mertens, PR1
Liakopoulos, V1
Phillips, BD1
Gopalakrishnan, G1
Gohh, R1
Hennessey, JV1
Somwaru, LL1
Arnold, AM1
Joshi, N1
Fried, LP1
Cappola, AR1
Tripepi, G1
Zoccali, C1
FRIIS, T2
OSTERGAARD KRISTENSEN, HP2
Shimizu, Y1
Nishihara, K1
Ji, L1
Okuda, M1
Piccoli, GB1
Mezza, E1
Burdese, M1
Terzolo, M1
Grassi, G1
Bermond, F1
Soragna, G1
Gai, M1
Dani, F1
Jeantet, A1
Segoloni, GP1
Piccoli, G1
Khundmiri, SJ1
Asghar, M1
Banday, AA1
Khan, F1
Salim, S1
Levi, M1
Yusufi, AN1
Sapin, R1
Schlienger, JL1
Kaltenbach, G1
Gasser, F1
Christofides, N1
Roul, G1
Gervais, A1
Petitjean, P1
Chambron, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Relation Between Thyroid , Parathyroid Hormones and Estimated Glomerular Filtration Rate in Chronic Kidney Disease Patients in Assiut[NCT05243979]80 participants (Anticipated)Observational2022-03-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

11 other studies available for triiodothyronine and Kidney Failure

ArticleYear
Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Mar-09, Volume: 101, Issue:10

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Digoxin; DNA, Complement

2004
Thyroid hormone status in patients with impaired kidney function.
    International urology and nephrology, 2021, Volume: 53, Issue:11

    Topics: Aged; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Prospective Studies; Re

2021
Lithium toxicity precipitated by profound hypothyroidism.
    Thyroid : official journal of the American Thyroid Association, 2008, Volume: 18, Issue:6

    Topics: Bipolar Disorder; Female; Humans; Hypothyroidism; Lithium Compounds; Middle Aged; Renal Insufficienc

2008
High frequency of and factors associated with thyroid hormone over-replacement and under-replacement in men and women aged 65 and over.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:4

    Topics: Aged; Body Mass Index; Body Weight; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Therap

2009
Low triiodothyronine and cardiovascular disease.
    Circulation, 2003, Jul-29, Volume: 108, Issue:4

    Topics: Biomarkers; Cardiovascular Diseases; Confounding Factors, Epidemiologic; Data Interpretation, Statis

2003
[In vitro uptake of labelled 1-triiodothyronine by human erythrocytes in chronic bronchitis with CO2 retention and in renal insufficiency].
    Ugeskrift for laeger, 1960, Nov-25, Volume: 122

    Topics: Bronchitis; Bronchitis, Chronic; Erythrocytes; In Vitro Techniques; Kidney Diseases; Renal Insuffici

1960
The in vitro uptake by human erythrocytes of labelled L-triiodothyronine in cases of chronic bronchitis with carbon dioxide retention and renal insufficiency.
    Acta endocrinologica, 1961, Volume: 36

    Topics: Bronchitis; Bronchitis, Chronic; Carbon Dioxide; Erythrocytes; Humans; In Vitro Techniques; Pyelonep

1961
Increased protein level of PEPT1 intestinal H+-peptide cotransporter upregulates absorption of glycylsarcosine and ceftibuten in 5/6 nephrectomized rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:4

    Topics: Animals; Blotting, Western; Ceftibuten; Cephalosporins; Dipeptides; Disease Progression; In Vitro Te

2005
Progression of renal failure without proteinuria in a patient with type 1 diabetes.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:12

    Topics: Adult; Biopsy; Creatine Kinase; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disease Progressi

2004
Effect of ischemia reperfusion on sodium-dependent phosphate transport in renal brush border membranes.
    Biochimica et biophysica acta, 2005, Oct-01, Volume: 1716, Issue:1

    Topics: Animals; Biological Transport; Blotting, Western; Cell Membrane; Ischemia; Kidney; Kidney Cortex; Ki

2005
Determination of free triiodothyronine by six different methods in patients with non-thyroidal illness and in patients treated with amiodarone.
    Annals of clinical biochemistry, 1995, Volume: 32 ( Pt 3)

    Topics: Adult; Aged; Amiodarone; Humans; Immunoassay; Liver Cirrhosis; Middle Aged; Renal Insufficiency; Sen

1995