triiodothyronine has been researched along with Iron Overload in 6 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)
Excerpt | Relevance | Reference |
---|---|---|
"Iron overload is a major problem in patients with b-thalassemia major, and it has many structural and metabolic consequences." | 1.38 | Effect of iron overload on endocrinopathies in patients with beta-thalassaemia major and intermedia. ( Kurtoglu, AU; Kurtoglu, E; Temizkan, AK, 2012) |
"L-Carnitine plays an important role in skeletal muscle bioenergetics, and its bioavailability and thus its import may be crucial for muscle function." | 1.35 | Hormonal and nutritional control of L-carnitine uptake in myoblastic C2C12 cells. ( Demarquoy, J; Georges, B; Le Borgne, F; Rigault, C, 2008) |
" It is concluded that hyperthyroidism increases the susceptibility of the liver to the toxic effects of iron, which seems to be related to the development of a severe oxidative stress status in the tissue, thus contributing to the concomitant liver injury and impairment of Kupffer cell phagocytosis and particle-induced respiratory burst activity." | 1.30 | Derangement of Kupffer cell functioning and hepatotoxicity in hyperthyroid rats subjected to acute iron overload. ( Basualdo, A; Boisier, X; Bosco, C; Carrión, Y; Cornejo, P; Fernández, V; Galleano, M; Puntarulo, S; Schön, M; Sepúlveda, A; Tapia, G; Videla, LA, 1999) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 4 (66.67) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Le Borgne, F | 1 |
Rigault, C | 1 |
Georges, B | 1 |
Demarquoy, J | 1 |
De Sanctis, V | 2 |
Tanas, R | 1 |
Gamberini, MR | 2 |
Sprocati, M | 1 |
Govoni, MR | 1 |
Marsella, M | 1 |
De Sanctis, E | 1 |
Ricchieri, P | 1 |
Gubellini, E | 1 |
Gilli, G | 1 |
Kurtoglu, AU | 1 |
Kurtoglu, E | 1 |
Temizkan, AK | 1 |
Boisier, X | 1 |
Schön, M | 1 |
Sepúlveda, A | 1 |
Basualdo, A | 1 |
Cornejo, P | 1 |
Bosco, C | 1 |
Carrión, Y | 1 |
Galleano, M | 1 |
Tapia, G | 1 |
Puntarulo, S | 1 |
Fernández, V | 1 |
Videla, LA | 1 |
Del Monte, U | 1 |
6 other studies available for triiodothyronine and Iron Overload
Article | Year |
---|---|
Hormonal and nutritional control of L-carnitine uptake in myoblastic C2C12 cells.
Topics: Blotting, Northern; Carnitine; Cell Line; Hormones; Humans; Insulin; Iron Compounds; Iron Overload; | 2008 |
Exaggerated TSH response to TRH ("sub-biochemical" hypothyroidism) in prepubertal and adolescent thalassaemic patients with iron overload: prevalence and 20-year natural history.
Topics: Adolescent; beta-Thalassemia; Child; Humans; Hypothyroidism; Iron Overload; Retrospective Studies; S | 2008 |
Mild subclinical hypothyroidism in thalassaemia major: prevalence, multigated radionuclide test, clinical and laboratory long-term follow-up study.
Topics: Adolescent; Adult; beta-Thalassemia; Child; Female; Humans; Hypothyroidism; Iron Overload; Longitudi | 2008 |
Effect of iron overload on endocrinopathies in patients with beta-thalassaemia major and intermedia.
Topics: Adolescent; Adult; beta-Thalassemia; Child; Endocrine System Diseases; Female; Ferritins; Glucose In | 2012 |
Derangement of Kupffer cell functioning and hepatotoxicity in hyperthyroid rats subjected to acute iron overload.
Topics: Animals; Hyperthyroidism; Iron Overload; Kupffer Cells; Male; Oxidative Stress; Oxygen Consumption; | 1999 |
Thyroid hormones, acute iron overload and the pathogenesis of cloudy swelling.
Topics: 2,4-Dinitrophenol; Acute Disease; Animals; Bacterial Toxins; Cell Nucleus; Cell Size; Edema; Guinea | 2001 |