triiodothyronine has been researched along with Invasiveness, Neoplasm in 20 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " T3 levels in postmenopausal women were positively associated with the risk of breast cancer in a dose-response manner." | 5.36 | Prospectively measured triiodothyronine levels are positively associated with breast cancer risk in postmenopausal women. ( Bondeson, AG; Bondeson, L; Ericsson, UB; Malm, J; Manjer, J; Tosovic, A, 2010) |
| " In this work, we demonstrate that the thyroid hormone triiodothyronine (T3) regulates actin remodeling and cell movement in breast cancer T-47D cells through the recruitment of FAK." | 3.85 | Thyroid Hormone Controls Breast Cancer Cell Movement via Integrin αV/β3/SRC/FAK/PI3-Kinases. ( Cuello-Carrión, FD; Flamini, MI; Jahn, GA; Mondaca, JM; Neira, FJ; Pennacchio, GE; Sanchez, AM; Simoncini, T; Uzair, ID, 2017) |
| "The incidence of thyroid nodules is increasing among patients in North America." | 1.46 | The T4/T3 quotient as a risk factor for differentiated thyroid cancer: a case control study. ( Florea, A; Forest, VI; Hier, M; Kay-Rivest, E; Payne, RJ; Sasson, M; Shoukrun, R; Tamilia, M, 2017) |
| "The effects of miR-130b on hepatocellular carcinoma (HCC) invasion were further examined in vitro and in vivo." | 1.42 | Repression of microRNA-130b by thyroid hormone enhances cell motility. ( Chen, CY; Chen, WJ; Chi, HC; Chung, IH; Huang, YH; Liao, CJ; Lin, KH; Lin, TP; Lin, YH; Tsai, CY; Tsai, MM; Tseng, YH; Wu, MH; Wu, SM; Yeh, YH, 2015) |
| "Overexpression of miR-21 promoted hepatoma cell migration and invasion, similar to that observed with T(3) stimulation in hepatoma cells." | 1.39 | Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma. ( Chen, CY; Chi, HC; Huang, YH; Hung, YT; Liao, CH; Liao, CJ; Lin, CD; Lin, KH; Lin, SY; Lin, YH; Tsai, CY; Tseng, YH; Wang, CJ; Wu, SM, 2013) |
| "Triiodothyronine (T3) is a potent form of thyroid hormone mediates several physiological processes including cellular growth, development, and differentiation via binding to the nuclear thyroid hormone receptor (TR)." | 1.39 | Thyroid hormone receptor inhibits hepatoma cell migration through transcriptional activation of Dickkopf 4. ( Chen, CY; Chen, WJ; Chi, HC; Chung, IH; Huang, YH; Liao, CH; Liao, CJ; Lin, KH; Lin, YH; Tsai, CY; Tseng, YH; Wu, SM; Wu, TI, 2013) |
| "In addition, C/EBP was upregulated in hepatoma cells after T(3) treatment and ectopic expression of MAT1A inhibited cell migration and invasion in J7 hepatoma cells." | 1.36 | Thyroid hormone receptor-mediated regulation of the methionine adenosyltransferase 1 gene is associated with cell invasion in hepatoma cell lines. ( Chen, WJ; Cheng, WL; Chien, LF; Huang, YH; Liao, CH; Liao, CJ; Lin, KH; Lu, YH; Tsai, MM; Wu, SM; Yeh, CT, 2010) |
| " T3 levels in postmenopausal women were positively associated with the risk of breast cancer in a dose-response manner." | 1.36 | Prospectively measured triiodothyronine levels are positively associated with breast cancer risk in postmenopausal women. ( Bondeson, AG; Bondeson, L; Ericsson, UB; Malm, J; Manjer, J; Tosovic, A, 2010) |
| "The invasiveness of MCF-7 human mammary carcinoma cells was tested in vitro via confronting cultures with embryonic chick heart fragments." | 1.28 | Retinoic acid modulates both invasion and plasma membrane ruffling of MCF-7 human mammary carcinoma cells in vitro. ( Bracke, ME; Mareel, MM; Van Larebeke, NA; Vyncke, BM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 13 (65.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meirovitz, A | 1 |
| Nisman, B | 1 |
| Allweis, TM | 1 |
| Carmon, E | 1 |
| Kadouri, L | 1 |
| Maly, B | 1 |
| Maimon, O | 1 |
| Peretz, T | 1 |
| Sasson, M | 1 |
| Kay-Rivest, E | 1 |
| Shoukrun, R | 1 |
| Florea, A | 1 |
| Hier, M | 1 |
| Forest, VI | 1 |
| Tamilia, M | 1 |
| Payne, RJ | 1 |
| Fussey, JM | 1 |
| Khan, H | 1 |
| Ahsan, F | 1 |
| Prashant, R | 1 |
| Pettit, L | 1 |
| Huang, YH | 9 |
| Lin, YH | 5 |
| Chi, HC | 6 |
| Liao, CH | 5 |
| Liao, CJ | 6 |
| Wu, SM | 7 |
| Chen, CY | 7 |
| Tseng, YH | 4 |
| Tsai, CY | 5 |
| Lin, SY | 1 |
| Hung, YT | 1 |
| Wang, CJ | 1 |
| Lin, CD | 1 |
| Lin, KH | 11 |
| Chung, IH | 3 |
| Wu, TI | 1 |
| Chen, WJ | 7 |
| Wu, MH | 2 |
| Tsai, MM | 6 |
| Lin, TP | 1 |
| Yeh, YH | 1 |
| Tai, PJ | 3 |
| Lin, SL | 1 |
| Schmohl, KA | 1 |
| Müller, AM | 1 |
| Wechselberger, A | 1 |
| Rühland, S | 1 |
| Salb, N | 1 |
| Schwenk, N | 1 |
| Heuer, H | 1 |
| Carlsen, J | 1 |
| Göke, B | 1 |
| Nelson, PJ | 1 |
| Spitzweg, C | 1 |
| Flamini, MI | 1 |
| Uzair, ID | 1 |
| Pennacchio, GE | 1 |
| Neira, FJ | 1 |
| Mondaca, JM | 1 |
| Cuello-Carrión, FD | 1 |
| Jahn, GA | 1 |
| Simoncini, T | 1 |
| Sanchez, AM | 1 |
| Liao, CS | 1 |
| Chen, RN | 2 |
| Kuo, LW | 1 |
| Yeh, CT | 3 |
| Yeh, SC | 1 |
| Cheng, WL | 3 |
| Pai, LM | 1 |
| Lu, YH | 1 |
| Chien, LF | 1 |
| Tosovic, A | 1 |
| Bondeson, AG | 1 |
| Bondeson, L | 1 |
| Ericsson, UB | 1 |
| Malm, J | 1 |
| Manjer, J | 1 |
| Chi, LM | 1 |
| Barber, KJ | 1 |
| Franklyn, JA | 1 |
| McCabe, CJ | 1 |
| Khanim, FL | 1 |
| Bulmer, JN | 1 |
| Whitley, GS | 1 |
| Kilby, MD | 1 |
| Lin, YW | 1 |
| Lee, HF | 1 |
| Liu, WL | 1 |
| Chen, ST | 1 |
| Chang, KS | 1 |
| Cheng, SY | 1 |
| Llanos, S | 1 |
| Iglesias, T | 1 |
| Riese, HH | 1 |
| Garrido, T | 1 |
| Caelles, C | 1 |
| Muñoz, A | 1 |
| Shieh, HY | 1 |
| Hsu, HC | 1 |
| Bracke, ME | 1 |
| Van Larebeke, NA | 1 |
| Vyncke, BM | 1 |
| Mareel, MM | 1 |
1 review available for triiodothyronine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Thyroid-stimulating hormone suppression therapy for differentiated thyroid cancer: The role for a combined T3/T4 approach.
Topics: Adenocarcinoma, Follicular; Combined Modality Therapy; Drug Therapy, Combination; Evidence-Based Med | 2017 |
19 other studies available for triiodothyronine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Thyroid Hormones and Morphological Features of Primary Breast Cancer.
Topics: Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Carcinoma in Situ; Cell Proliferation; Female; Hum | 2022 |
The T4/T3 quotient as a risk factor for differentiated thyroid cancer: a case control study.
Topics: Biomarkers, Tumor; Case-Control Studies; Disease-Free Survival; Female; Humans; Logistic Models; Mal | 2017 |
Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Gene Ex | 2013 |
Thyroid hormone receptor inhibits hepatoma cell migration through transcriptional activation of Dickkopf 4.
Topics: Animals; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Humans; Intercellular Signal | 2013 |
Repression of microRNA-130b by thyroid hormone enhances cell motility.
Topics: Aged; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Disease Progression; Down-Regulati | 2015 |
Thyroid hormone-mediated regulation of lipocalin 2 through the Met/FAK pathway in liver cancer.
Topics: Acute-Phase Proteins; Animals; Blotting, Western; Cell Line, Tumor; Cell Movement; Focal Adhesion Ki | 2015 |
Thyroid hormones and tetrac: new regulators of tumour stroma formation via integrin αvβ3.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Differentia | 2015 |
Thyroid Hormone Controls Breast Cancer Cell Movement via Integrin αV/β3/SRC/FAK/PI3-Kinases.
Topics: Actin Cytoskeleton; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Female; Focal | 2017 |
Regulation of AKR1B1 by thyroid hormone and its receptors.
Topics: Aldehyde Reductase; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cycloheximide; Enz | 2009 |
Positive regulation of spondin 2 by thyroid hormone is associated with cell migration and invasion.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cells, Cultured; Extracellular | 2010 |
Thyroid hormone receptor-mediated regulation of the methionine adenosyltransferase 1 gene is associated with cell invasion in hepatoma cell lines.
Topics: Base Sequence; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Cell Mo | 2010 |
Prospectively measured triiodothyronine levels are positively associated with breast cancer risk in postmenopausal women.
Topics: Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cohort Studies; Female; Follow-Up Studies | 2010 |
Cathepsin H regulated by the thyroid hormone receptors associate with tumor invasion in human hepatoma cells.
Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cathepsin H; Cell Movement; Gene Expression Regul | 2011 |
Stable isotope labeling with amino acids in cell culture (SILAC)-based quantitative proteomics study of a thyroid hormone-regulated secretome in human hepatoma cells.
Topics: Amino Acids; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; | 2012 |
The in vitro effects of triiodothyronine on epidermal growth factor-induced trophoblast function.
Topics: Cell Division; Cell Line, Transformed; Cell Movement; Choriocarcinoma; Epidermal Growth Factor; Fema | 2005 |
Increased invasive activity of human hepatocellular carcinoma cells is associated with an overexpression of thyroid hormone beta 1 nuclear receptor and low expression of the anti-metastatic nm23 gene.
Topics: Carcinoma, Hepatocellular; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Liver Ne | 1995 |
v-erbA oncogene induces invasiveness and anchorage-independent growth in cultured glial cells by mechanisms involving platelet-derived growth factor.
Topics: Animals; Becaplermin; Blood; Cell Adhesion; Cell Count; Cell Division; Cell Line; Cell Transformatio | 1996 |
Negative regulation of the antimetastatic gene Nm23-H1 by thyroid hormone receptors.
Topics: Base Sequence; DNA; Gene Expression Regulation; Humans; Molecular Sequence Data; Monomeric GTP-Bindi | 2000 |
Retinoic acid modulates both invasion and plasma membrane ruffling of MCF-7 human mammary carcinoma cells in vitro.
Topics: Animals; Breast Neoplasms; Cell Aggregation; Cell Division; Cell Line; Cell Membrane; Chick Embryo; | 1991 |