Page last updated: 2024-11-08

triiodothyronine and Inflammation

triiodothyronine has been researched along with Inflammation in 61 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
" Depression could result from changes in tryptophan availability caused by activation of the kynurenine pathway as a result of inflammation."9.14Kynurenine metabolites and inflammation markers in depressed patients treated with fluoxetine or counselling. ( Bridel, MA; Christofides, J; Cowlard, R; Darlington, LG; Forrest, CM; Mackay, GM; Mitchell, S; Stone, TW, 2009)
"- This prospective study in prevalent dialysis patients investigated prognostic properties of low triiodothyronine syndrome, protein-energy wasting and chronic inflammation."7.88THE ASSOCIATION OF LOW TRIIODOTHYRONINE SYNDROME, PROTEIN-ENERGY WASTING AND CHRONIC INFLAMMATION WITH MORTALITY IN PREVALENT DIALYSIS PATIENTS. ( Altabas, K; Črne Fureš, N; Lucijanić, M; Pavlović, D; Žabić, I, 2018)
"Patients with acute ischemic stroke (AIS) frequently experience low free triiodothyronine (fT3) concentrations."7.83Low triiodothyronine: A new facet of inflammation in acute ischemic stroke. ( Chen, X; Jiang, Y; Liu, M; Liu, Y; Ma, L; Ma, X; Zhu, D, 2016)
"Little is known about the impact of low triiodothyronine (T3) levels on mortality in end-stage renal disease (ESRD) patients starting hemodialysis (HD) and whether this impact is mediated by malnutrition, inflammation, or cardiac dysfunction."7.79The impact of low triiodothyronine levels on mortality is mediated by malnutrition and cardiac dysfunction in incident hemodialysis patients. ( Doh, FM; Han, JH; Han, JS; Han, SH; Kang, SW; Kim, CH; Kim, EJ; Koo, HM; Lee, MJ; Oh, HJ; Yoo, TH, 2013)
"Low plasma triiodothyronine (T(3)) levels are considered a prognostic predictor of death in heart failure (HF) patients."7.77Low plasma triiodothyronine levels in heart failure are associated with a reduced anabolic state and membrane damage. ( Acosta, A; Anker, S; Boero, L; Brenta, G; Brites, F; Gómez Rosso, L; Sutton, M; Thierer, J; Vainstein, N, 2011)
"Leptin did not have an effect on both cytokine responses (proinflammatory and anti-inflammatory) in the time of LPS-induced acute inflammation."7.71Does leptin modulate immune and endocrine response in the time of LPS-induced acute inflammation? ( Baranowska, B; Bik, W; Chmielowska, M; Rusiecka-Kuczalek, E; Wolinska-Witort, E, 2001)
"Triiodothyronine (T3) has been shown to exert a defensive role in many pulmonary diseases, however, rare data are available regarding the role of T3 on silica-induced injury."5.62Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice. ( Chen, W; Fan, L; Gan, S; Ma, J; Wang, B; Wang, D; Xie, Y; Yang, M; Yu, L, 2021)
"Magnesium sulfate (MgSO4) has anti-inflammatory actions."5.43Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism. ( Abbas, AM; Sakr, HF, 2016)
"Free triiodothyronine (FT3) is a marker of comorbidity in end-stage renal disease and in many acute and chronic diseases."5.40Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation. ( Altinoglu, A; Altunoglu, A; Arat, Z; Canoz, MB; Elsürer, R; Ozdemir, FN; Sezer, S; Yavuz, D; Yavuz, R, 2014)
" Depression could result from changes in tryptophan availability caused by activation of the kynurenine pathway as a result of inflammation."5.14Kynurenine metabolites and inflammation markers in depressed patients treated with fluoxetine or counselling. ( Bridel, MA; Christofides, J; Cowlard, R; Darlington, LG; Forrest, CM; Mackay, GM; Mitchell, S; Stone, TW, 2009)
"The NSAIDs ibuprofen and diclofenac were administered to C57BL/6 mice after induction of pancreatitis with serial injections of cerulein."3.88Ibuprofen and diclofenac treatments reduce proliferation of pancreatic acinar cells upon inflammatory injury and mitogenic stimulation. ( Bombardo, M; Chen, R; Graf, R; Malagola, E; Rudnicka, A; Sonda, S, 2018)
"- This prospective study in prevalent dialysis patients investigated prognostic properties of low triiodothyronine syndrome, protein-energy wasting and chronic inflammation."3.88THE ASSOCIATION OF LOW TRIIODOTHYRONINE SYNDROME, PROTEIN-ENERGY WASTING AND CHRONIC INFLAMMATION WITH MORTALITY IN PREVALENT DIALYSIS PATIENTS. ( Altabas, K; Črne Fureš, N; Lucijanić, M; Pavlović, D; Žabić, I, 2018)
"Patients with acute ischemic stroke (AIS) frequently experience low free triiodothyronine (fT3) concentrations."3.83Low triiodothyronine: A new facet of inflammation in acute ischemic stroke. ( Chen, X; Jiang, Y; Liu, M; Liu, Y; Ma, L; Ma, X; Zhu, D, 2016)
"Little is known about the impact of low triiodothyronine (T3) levels on mortality in end-stage renal disease (ESRD) patients starting hemodialysis (HD) and whether this impact is mediated by malnutrition, inflammation, or cardiac dysfunction."3.79The impact of low triiodothyronine levels on mortality is mediated by malnutrition and cardiac dysfunction in incident hemodialysis patients. ( Doh, FM; Han, JH; Han, JS; Han, SH; Kang, SW; Kim, CH; Kim, EJ; Koo, HM; Lee, MJ; Oh, HJ; Yoo, TH, 2013)
"Low plasma triiodothyronine (T(3)) levels are considered a prognostic predictor of death in heart failure (HF) patients."3.77Low plasma triiodothyronine levels in heart failure are associated with a reduced anabolic state and membrane damage. ( Acosta, A; Anker, S; Boero, L; Brenta, G; Brites, F; Gómez Rosso, L; Sutton, M; Thierer, J; Vainstein, N, 2011)
"36 mU/L) and again in the same patients during subclinical hyperthyroidism secondary to exogenous levothyroxine administration (TSH 0."3.76Improved endothelial function and lipid profile compensate for impaired hemostatic and inflammatory status in iatrogenic chronic subclinical hyperthyroidism of thyroid cancer patients on L-t4 therapy. ( Burman, KD; Gazdag, A; Jenei, Z; Nagy, EV; Paragh, G, 2010)
"Leptin did not have an effect on both cytokine responses (proinflammatory and anti-inflammatory) in the time of LPS-induced acute inflammation."3.71Does leptin modulate immune and endocrine response in the time of LPS-induced acute inflammation? ( Baranowska, B; Bik, W; Chmielowska, M; Rusiecka-Kuczalek, E; Wolinska-Witort, E, 2001)
" The anti-inflammatory activity of Indomethacin, Oxametacine and Phenylbutazone was evaluated in these animals using paw oedema provoked by carrageenan granulomas induced by cotton pellets and polyarthritis induced by Freund complete adjuvant."3.66The influence of experimental hypo- and hyperthyroid states on acute and chronic inflammatory reactions: modified response to non-steroidal anti-inflammatory agents. ( Cirillo, R; Curzio, M; Franzone, J; Sena, L; Torrielli, MV, 1981)
"Triiodothyronine (T3) has been shown to exert a defensive role in many pulmonary diseases, however, rare data are available regarding the role of T3 on silica-induced injury."1.62Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice. ( Chen, W; Fan, L; Gan, S; Ma, J; Wang, B; Wang, D; Xie, Y; Yang, M; Yu, L, 2021)
"Moreover, hyperinsulinemia reduces the circulating level of serum T4 and conversion of T4 to T3, mimicking hypothyroidism, because thyroid hormones are necessary for the maturation of chondrocytes."1.46Serum insulin in pathogenesis and treatment of osteoarthritis. ( Askari, A; Bahramali, E; Ehrampoush, E; Farjam, M; Homayounfar, R, 2017)
"Magnesium sulfate (MgSO4) has anti-inflammatory actions."1.43Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism. ( Abbas, AM; Sakr, HF, 2016)
"Hypothyroidism has been linked with low grade inflammation, elevated risk of hepatic steatosis and atherosclerosis."1.40Thyroid hormone status regulates the expression of secretory phospholipases. ( Boilard, E; Levesque, T; Park, EA; Sharma, P, 2014)
"Free triiodothyronine (FT3) is a marker of comorbidity in end-stage renal disease and in many acute and chronic diseases."1.40Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation. ( Altinoglu, A; Altunoglu, A; Arat, Z; Canoz, MB; Elsürer, R; Ozdemir, FN; Sezer, S; Yavuz, D; Yavuz, R, 2014)

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-19908 (13.11)18.7374
1990's1 (1.64)18.2507
2000's10 (16.39)29.6817
2010's37 (60.66)24.3611
2020's5 (8.20)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Doshi, M1
Watanabe, S1
Natori, Y1
Hosoyamada, M1
Hirashima-Akae, Y1
Liu, Q1
Li, H1
He, W1
Zhao, Q1
Huang, C1
Wang, Q1
Zheng, Z1
Zhang, X1
Shi, X1
Li, X1
Gan, S2
Yang, M2
Fan, L2
Xie, L1
Xu, Y1
Wang, B2
Xu, T1
Yu, L2
Ma, J2
Chen, W2
Mishra, J1
Vishwakarma, J1
Malik, R1
Gupta, K1
Pandey, R1
Maurya, SK1
Garg, A1
Shukla, M1
Chattopadhyay, N1
Bandyopadhyay, S1
Wang, D1
Xie, Y1
Bombardo, M1
Malagola, E1
Chen, R1
Rudnicka, A1
Graf, R1
Sonda, S1
Zhou, X1
Yu, F1
Feng, X1
Wang, J1
Li, Z1
Zhan, Q1
Xia, J1
Gu, Y1
Wang, Y2
Zhang, Q1
Liu, L1
Meng, G1
Yao, Z1
Wu, H1
Xia, Y1
Bao, X1
Shi, H1
Wang, H1
Sun, S1
Wang, X1
Zhou, M1
Jia, Q1
Song, K1
Niu, K1
Zhang, K1
Tang, YD1
Zhang, Y1
Ojamaa, K1
Li, Y1
Saini, AS1
Carrillo-Sepulveda, MA1
Rajagopalan, V1
Gerdes, AM1
van der Spek, AH1
Surovtseva, OV3
Jim, KK1
van Oudenaren, A1
Brouwer, MC1
Vandenbroucke-Grauls, CMJE1
Leenen, PJM1
van de Beek, D1
Hernandez, A1
Fliers, E4
Boelen, A4
Nascimento, BPP1
Bocco, BMLC1
Fernandes, GW1
Fonseca, TL1
McAninch, EA1
Cardoso, CV1
Bondan, EF1
Nassif, RJ1
Cysneiros, RM1
Bianco, AC1
Ribeiro, MO1
Ha, HC1
Jang, JM1
Zhou, D1
Kim, HG1
Back, MJ1
Shin, IC1
Yun, SY1
Piao, Y1
Choi, JM1
Won, JH1
Kim, DK1
Qin, SL1
He, Q1
Hu, L1
He, CY1
Gao, LC1
Young, CA1
Chen, J1
Jiang, CF1
Luo, XF1
Zhou, Y1
Sheng, X1
Li, ZH1
Chen, ML1
Xu, G2
Alamino, VA1
Montesinos, MDM1
Soler, MF1
Giusiano, L1
Gigena, N1
Fozzatti, L1
Maller, SM1
Méndez-Huergo, SP1
Rabinovich, GA1
Pellizas, CG1
Seyedhosseini Tamijani, SM1
Beirami, E1
Ahmadiani, A1
Dargahi, L1
Črne Fureš, N1
Lucijanić, M1
Žabić, I1
Altabas, K1
Pavlović, D1
Fontana, L1
Addante, F1
Copetti, M1
Paroni, G1
Fontana, A1
Sancarlo, D1
Pellegrini, F1
Ferrucci, L1
Pilotto, A1
Koo, HM1
Kim, CH1
Doh, FM1
Lee, MJ1
Kim, EJ1
Han, JH1
Han, JS1
Oh, HJ1
Han, SH1
Yoo, TH1
Kang, SW1
Ferreyra, C1
Vargas, F1
Rodríguez-Gómez, I1
Pérez-Abud, R1
O'Valle, F1
Osuna, A1
Perrotta, C1
Buldorini, M1
Assi, E1
Cazzato, D1
De Palma, C1
Clementi, E1
Cervia, D1
Sharma, P1
Levesque, T1
Boilard, E1
Park, EA1
Kwakkel, J2
de Vries, EM1
Stap, J1
Yavuz, D1
Sezer, S1
Yavuz, R1
Canoz, MB1
Altunoglu, A1
Altinoglu, A1
Elsürer, R1
Arat, Z1
Ozdemir, FN1
Yan, Y1
Liu, Y2
Nijampurkar, B1
Qureshi, F1
Jain, N1
Banerjee, T1
Kumar, A1
Parmar, HS1
Abbas, AM1
Sakr, HF1
Banks, R1
Delibegovic, M1
Stevenson, TJ1
Mancini, A1
Di Segni, C1
Raimondo, S1
Olivieri, G1
Silvestrini, A1
Meucci, E1
Currò, D1
Ma, L1
Zhu, D1
Jiang, Y1
Ma, X1
Liu, M1
Chen, X1
Chi, HC1
Chen, SL2
Tsai, CY1
Chuang, WY1
Huang, YH2
Tsai, MM1
Wu, SM1
Sun, CP1
Yeh, CT1
Lin, KH2
Askari, A1
Ehrampoush, E1
Homayounfar, R1
Bahramali, E1
Farjam, M1
Li, T1
Lee, W1
Hara, H1
Long, C1
Ezzelarab, M1
Ayares, D1
Huang, H1
Esmon, CT1
Cooper, DKC1
Iwase, H1
Mackay, GM1
Forrest, CM1
Christofides, J1
Bridel, MA1
Mitchell, S1
Cowlard, R1
Stone, TW1
Darlington, LG1
Gazdag, A1
Nagy, EV1
Burman, KD1
Paragh, G1
Jenei, Z1
Fernández-Reyes, MJ1
Sánchez, R1
Heras, M1
Tajada, P1
Iglesias, P1
García, L1
García Arévalo, MC1
Molina, A1
Rodríguez, A1
Alvarez-Ude, F1
Chamorro, C1
Falcón, JA1
Michelena, JC1
Lubrano, V1
Pingitore, A2
Carpi, A1
Iervasi, G2
Yilmaz, MI1
Sonmez, A1
Karaman, M1
Ay, SA1
Saglam, M1
Yaman, H1
Kilic, S1
Eyileten, T1
Caglar, K1
Oguz, Y1
Vural, A1
Yenicesu, M1
Zoccali, C2
Zeraati, AA1
Layegh, P1
Famili, Y1
Naghibi, M1
Sharifipour, F1
Shariati Sarabi, Z1
van Zeijl, CJ1
Wiersinga, WM1
Rozing, MP1
Westendorp, RG1
Maier, AB1
Wijsman, CA1
Frölich, M1
de Craen, AJ1
van Heemst, D1
Brenta, G1
Thierer, J1
Sutton, M1
Acosta, A1
Vainstein, N1
Brites, F1
Boero, L1
Gómez Rosso, L1
Anker, S1
Priest, JR1
Slee, A1
Olson, AK1
Ledee, D1
Morrish, F1
Portman, MA1
BEDELL, RH1
BULLE, PH1
O'ROURKE, J1
MANCINO, D1
SENA, L2
SALVATORE, G1
Shih, CH1
Yen, CC1
Chen, CD1
Lee, YS1
Velayoudom, FL1
Marchandise, X1
Nocaudie, M1
d'Herbomez, M1
Docao, C1
Bauters, C1
Regnier, F1
Wemeau, JL1
Barison, A1
Prontera, C1
Pratali, L1
Emdin, M1
Giannessi, D1
Neglia, D1
Enia, G1
Panuccio, V1
Cutrupi, S1
Pizzini, P1
Tripepi, G1
Mallamaci, F1
Torrielli, MV1
Franzone, J1
Curzio, M1
Cirillo, R1
Franzone, JS1
Cravanzola, C1
Reboani, MC1
Dietrich, JB1
Zaepfel, M1
Kuchler-Bopp, S1
Armstrong, TA1
Spears, JW1
Lloyd, KE1
Bik, W1
Wolinska-Witort, E1
Chmielowska, M1
Rusiecka-Kuczalek, E1
Baranowska, B1
Noto, H1
Tsukamoto, K1
Hayashi, S1
Takano, K1
Fujita, T1
Kimura, S1
Woloski, BM1
Jamieson, JC1
Jorns, G2
Sedlarik, K2
Steinetz, B1
Giannina, T1
Butler, M1
Popick, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prediction and Management of Delayed Graft Function Based on Donor Criteria and LifePort Platform[NCT02876692]1,000 participants (Anticipated)Observational2016-01-31Recruiting
Evaluation of the Effects of N-acetylcysteine on Thyroid Hormone Levels in the Low T3 Syndrome[NCT01501110]Phase 483 participants (Actual)Interventional2011-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Serum T3 Levels at 48 Hours

(NCT01501110)
Timeframe: 48 hours

Interventionng/dL (Mean)
N-acetylcysteine93.5
no Intervention96.5

Reviews

3 reviews available for triiodothyronine and Inflammation

ArticleYear
Thyroid Hormones, Oxidative Stress, and Inflammation.
    Mediators of inflammation, 2016, Volume: 2016

    Topics: Animals; Humans; Inflammation; Oxidative Stress; Thyroid Hormones; Thyroxine; Triiodothyronine

2016
Controversial points in organ donor management.
    Transplantation proceedings, 2009, Volume: 41, Issue:8

    Topics: Anti-Inflammatory Agents; Brain; Brain Death; Deamino Arginine Vasopressin; Humans; Hypothalamo-Hypo

2009
Beyond low plasma T3: local thyroid hormone metabolism during inflammation and infection.
    Endocrine reviews, 2011, Volume: 32, Issue:5

    Topics: Acute Disease; Adipose Tissue; Bacterial Infections; Chronic Disease; Euthyroid Sick Syndromes; Gene

2011

Trials

2 trials available for triiodothyronine and Inflammation

ArticleYear
Kynurenine metabolites and inflammation markers in depressed patients treated with fluoxetine or counselling.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:4

    Topics: Adult; Antidepressive Agents; Biomarkers; Counseling; Depression; Drug Therapy, Combination; Female;

2009
Triiodothyronine supplementation and cytokines during cardiopulmonary bypass in infants and children.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 144, Issue:4

    Topics: Age Factors; Airway Extubation; Analysis of Variance; Biomarkers; Cardiopulmonary Bypass; Cytokines;

2012

Other Studies

56 other studies available for triiodothyronine and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Triiodothyronine Aggravates Global Cerebral Ischemia-Reperfusion Injury in Mice.
    Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:12

    Topics: Animals; Astrocytes; Brain Ischemia; Cell Death; Cerebral Infarction; Disease Models, Animal; DNA Fr

2021
Role of aerobic exercise in ameliorating NASH: Insights into the hepatic thyroid hormone signaling and circulating thyroid hormones.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Animals; Inflammation; Liver Cirrhosis; Mice; Non-alcoholic Fatty Liver Disease; Physical Conditioni

2022
Triiodothyronine Attenuates Silica-Induced Oxidative Stress, Inflammation, and Apoptosis via Thyroid Hormone Receptor α in Differentiated THP-1 Macrophages.
    Chemical research in toxicology, 2020, 05-18, Volume: 33, Issue:5

    Topics: Apoptosis; Cell Differentiation; Dose-Response Relationship, Drug; Humans; Inflammation; Macrophages

2020
Hypothyroidism Induces Interleukin-1-Dependent Autophagy Mechanism as a Key Mediator of Hippocampal Neuronal Apoptosis and Cognitive Decline in Postnatal Rats.
    Molecular neurobiology, 2021, Volume: 58, Issue:3

    Topics: Animals; Animals, Newborn; Apoptosis; Autophagy; Cognitive Dysfunction; Hippocampus; Hypothyroidism;

2021
Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
    The Science of the total environment, 2021, Oct-10, Volume: 790

    Topics: Animals; Fibrosis; Inflammation; Lung; Mice; Mice, Inbred C57BL; Pneumonia; Pulmonary Fibrosis; Sili

2021
Ibuprofen and diclofenac treatments reduce proliferation of pancreatic acinar cells upon inflammatory injury and mitogenic stimulation.
    British journal of pharmacology, 2018, Volume: 175, Issue:2

    Topics: Acinar Cells; Animals; Cell Differentiation; Cell Proliferation; Ceruletide; Cytokines; Diclofenac;

2018
Immunity and inflammation predictors for short-term outcome of stroke in young adults.
    The International journal of neuroscience, 2018, Volume: 128, Issue:7

    Topics: Adolescent; Adult; Blood Glucose; Female; Globulins; Humans; Immunity; Inflammation; Leukocyte Count

2018
The association between thyroid function and incidence of metabolic syndrome in euthyroid subjects: Tianjin chronic low-grade systemic inflammation and health cohort study.
    Clinical endocrinology, 2018, Volume: 88, Issue:5

    Topics: Adult; China; Cohort Studies; Female; Humans; Incidence; Inflammation; Male; Metabolic Syndrome; Mid

2018
Comparison of Therapeutic Triiodothyronine Versus Metoprolol in the Treatment of Myocardial Infarction in Rats.
    Thyroid : official journal of the American Thyroid Association, 2018, Volume: 28, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Echocardiography; Ele

2018
Regulation of Intracellular Triiodothyronine Is Essential for Optimal Macrophage Function.
    Endocrinology, 2018, 05-01, Volume: 159, Issue:5

    Topics: Animals; Cell Differentiation; Cytokines; Embryo, Nonmammalian; Gene Knockdown Techniques; Immunity,

2018
Induction of Type 2 Iodothyronine Deiodinase After Status Epilepticus Modifies Hippocampal Gene Expression in Male Mice.
    Endocrinology, 2018, 08-01, Volume: 159, Issue:8

    Topics: Amygdala; Animals; Apoptosis; Astrocytes; Cell Death; Cell Nucleus; Gene Expression; Hippocampus; In

2018
3, 5, 3'-Triiodothyroacetic acid (TRIAC) is an anti-inflammatory drug that targets toll-like receptor 2.
    Archives of pharmacal research, 2018, Volume: 41, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Humans; Inflammation; Male; Mice; Mice, Inbred B

2018
The relationship between inflammatory factors, oxidative stress and DIO-1 concentration in patients with chronic renal failure accompanied with or without euthyroid sick syndrome.
    The Journal of international medical research, 2018, Volume: 46, Issue:10

    Topics: Aged; Biological Factors; Cytokines; DNA-Binding Proteins; Euthyroid Sick Syndromes; Female; Humans;

2018
Dendritic Cells Exposed to Triiodothyronine Deliver Pro-Inflammatory Signals and Amplify IL-17-Driven Immune Responses.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2019, Volume: 52, Issue:2

    Topics: Animals; B7-H1 Antigen; CD4-Positive T-Lymphocytes; Cell Proliferation; Dendritic Cells; Gene Expres

2019
Thyroid hormone treatment alleviates the impairments of neurogenesis, mitochondrial biogenesis and memory performance induced by methamphetamine.
    Neurotoxicology, 2019, Volume: 74

    Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cognition; Cognition Disorders; Double

2019
THE ASSOCIATION OF LOW TRIIODOTHYRONINE SYNDROME, PROTEIN-ENERGY WASTING AND CHRONIC INFLAMMATION WITH MORTALITY IN PREVALENT DIALYSIS PATIENTS.
    Acta clinica Croatica, 2018, Volume: 57, Issue:3

    Topics: Aged; C-Reactive Protein; Croatia; Energy Metabolism; Female; Humans; Inflammation; Male; Middle Age

2018
Identification of a metabolic signature for multidimensional impairment and mortality risk in hospitalized older patients.
    Aging cell, 2013, Volume: 12, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Blood Sedimentation; C-Reactive Protein; Cholesterol, LD

2013
The impact of low triiodothyronine levels on mortality is mediated by malnutrition and cardiac dysfunction in incident hemodialysis patients.
    European journal of endocrinology, 2013, Volume: 169, Issue:4

    Topics: Adult; Aged; Echocardiography; Female; Heart Diseases; Humans; Incidence; Inflammation; Kaplan-Meier

2013
Preconditioning with triiodothyronine improves the clinical signs and acute tubular necrosis induced by ischemia/reperfusion in rats.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Animals; Biopsy; Glutathione; Immunohistochemistry; Inflammation; Interleukin-6; Ischemic Preconditi

2013
The thyroid hormone triiodothyronine controls macrophage maturation and functions: protective role during inflammation.
    The American journal of pathology, 2014, Volume: 184, Issue:1

    Topics: Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Female; Flow Cytometry; Immunophe

2014
Thyroid hormone status regulates the expression of secretory phospholipases.
    Biochemical and biophysical research communications, 2014, Jan-31, Volume: 444, Issue:1

    Topics: Anilides; Animals; Gene Expression Regulation, Enzymologic; Group II Phospholipases A2; Hep G2 Cells

2014
A novel role for the thyroid hormone-activating enzyme type 2 deiodinase in the inflammatory response of macrophages.
    Endocrinology, 2014, Volume: 155, Issue:7

    Topics: Animals; Cell Line; Cell Line, Tumor; Female; Gene Expression; Granulocyte-Macrophage Colony-Stimula

2014
Free triiodothyronine in hemodialysis patients: link with malnutrition and inflammation.
    Iranian journal of kidney diseases, 2014, Volume: 8, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Female; Humans; Inflamm

2014
The cardiovascular disease risks of nonthyroidal illness syndrome and inflammatory responses on patients with chronic kidney disease: from the association to clinical prognosis.
    Cardiovascular therapeutics, 2014, Volume: 32, Issue:6

    Topics: Adult; Aged; Cardiovascular Diseases; Echocardiography; Female; Humans; Hypertrophy, Left Ventricula

2014
Anti-Inflammatory Role of Thyroid Hormones on Rat Air Pouch Model of Inflammation.
    Inflammation & allergy drug targets, 2015, Volume: 14, Issue:2

    Topics: Air; Animals; Anti-Infective Agents; Carrageenan; Disease Models, Animal; Glutathione; Inflammation;

2015
Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism.
    Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:4

    Topics: Animals; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Hypothyroidism; Inflammation; Inte

2016
Photoperiod- and Triiodothyronine-dependent Regulation of Reproductive Neuropeptides, Proinflammatory Cytokines, and Peripheral Physiology in Siberian Hamsters (Phodopus sungorus).
    Journal of biological rhythms, 2016, Volume: 31, Issue:3

    Topics: Animals; Body Weight; Circadian Rhythm; Cricetinae; Cytokines; Gonads; Hypothalamus; Inflammation; M

2016
Low triiodothyronine: A new facet of inflammation in acute ischemic stroke.
    Clinica chimica acta; international journal of clinical chemistry, 2016, Jul-01, Volume: 458

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Female; Humans; Inflammation; Male; Middle Aged; Str

2016
Thyroid hormone suppresses hepatocarcinogenesis via DAPK2 and SQSTM1-dependent selective autophagy.
    Autophagy, 2016, Volume: 12, Issue:12

    Topics: Animals; Autophagy; Carcinogenesis; Carcinoma, Hepatocellular; Death-Associated Protein Kinases; Die

2016
Serum insulin in pathogenesis and treatment of osteoarthritis.
    Medical hypotheses, 2017, Volume: 99

    Topics: Adipokines; Cartilage; Cell Differentiation; Cell Proliferation; Chondrocytes; Disease Progression;

2017
An Investigation of Extracellular Histones in Pig-To-Baboon Organ Xenotransplantation.
    Transplantation, 2017, Volume: 101, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Arteries; Blood Coagulation; B

2017
Improved endothelial function and lipid profile compensate for impaired hemostatic and inflammatory status in iatrogenic chronic subclinical hyperthyroidism of thyroid cancer patients on L-t4 therapy.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2010, Volume: 118, Issue:6

    Topics: Adult; C-Reactive Protein; Endothelium, Vascular; Female; Fibrinogen; Humans; Hyperthyroidism; Hypot

2010
[Can FT3 levels facilitate the detection of inflammation or catabolism and malnutrition in dialysis patients?].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2009, Volume: 29, Issue:4

    Topics: Aged; Cross-Sectional Studies; Female; Humans; Inflammation; Male; Malnutrition; Renal Dialysis; Tri

2009
Relationship between triiodothyronine and proinflammatory cytokines in chronic heart failure.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:3

    Topics: Adult; Aged; C-Reactive Protein; Disease Progression; Female; Heart Failure; Humans; Inflammation; I

2010
Low triiodothyronine alters flow-mediated vasodilatation in advanced nondiabetic kidney disease.
    American journal of nephrology, 2011, Volume: 33, Issue:1

    Topics: Adult; Diabetes Mellitus; Female; Humans; Hypothyroidism; Inflammation; Kidney Diseases; Male; Middl

2011
Serum triiodothyronine level as an indicator of inflammation in patients undergoing dialysis.
    Iranian journal of kidney diseases, 2011, Volume: 5, Issue:1

    Topics: Adult; Biomarkers; C-Reactive Protein; Case-Control Studies; Chi-Square Distribution; Cross-Sectiona

2011
Acute inflammation increases pituitary and hypothalamic glycoprotein hormone subunit B5 mRNA expression in association with decreased thyrotrophin receptor mRNA expression in mice.
    Journal of neuroendocrinology, 2011, Volume: 23, Issue:4

    Topics: Animals; Female; Gene Expression; Glycoproteins; Hypothalamus; Inflammation; Interleukin-1beta; Iodi

2011
Serum triiodothyronine levels and inflammatory cytokine production capacity.
    Age (Dordrecht, Netherlands), 2012, Volume: 34, Issue:1

    Topics: Aged, 80 and over; Aging; Biomarkers; Cytokines; Female; Humans; Inflammation; Male; Triiodothyronin

2012
Low plasma triiodothyronine levels in heart failure are associated with a reduced anabolic state and membrane damage.
    European journal of endocrinology, 2011, Volume: 164, Issue:6

    Topics: Aged; Biomarkers; Cardiomyopathy, Dilated; Echocardiography; Electric Impedance; Exercise Test; Fema

2011
TRIIODOTHYRONINE, HYPERTHERMIA, AND CORTICOSTEROID INFLUENCE ON ISOLATED IRIS TISSUE RESPIRATION.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1963, Volume: 70

    Topics: Adrenal Cortex Hormones; Animals; Aqueous Humor; Dexamethasone; Fever; Inflammation; Iris; Liver; Me

1963
[RELATIONS BETWEEN THYROID FUNCTION AND INFLAMMATION. I. EFFECTS OF THYROIDECTOMY AND ADMINISTRATION OF TRIIODOTHYRONINE ON GRANULOMATOUS PSEUDOCYSTS DUE TO AMORPHOUS SILICA, IN RAT SUBCUTANEOUS TISSUE].
    Archivio "de Vecchi" per l'anatomia patologica e la medicina clinica, 1964, Volume: 44

    Topics: Granuloma; Inflammation; Rats; Research; Silicon Dioxide; Subcutaneous Fat; Subcutaneous Tissue; Thy

1964
Thyroid hormone receptor-dependent transcriptional regulation of fibrinogen and coagulation proteins.
    Endocrinology, 2004, Volume: 145, Issue:6

    Topics: Animals; Blood Coagulation Factors; Blood Proteins; Cell Line, Tumor; Cycloheximide; Fibrinogen; Gen

2004
[131 iodine for the treatment of benign goiters].
    Presse medicale (Paris, France : 1983), 2005, Jan-29, Volume: 34, Issue:2 Pt 1

    Topics: Aged; Aged, 80 and over; Autoantibodies; Drug Monitoring; Drug Utilization; Female; Goiter; Humans;

2005
Early activation of an altered thyroid hormone profile in asymptomatic or mildly symptomatic idiopathic left ventricular dysfunction.
    Journal of cardiac failure, 2006, Volume: 12, Issue:7

    Topics: Aged; Cardiac Output, Low; Female; Hormones; Humans; Inflammation; Interleukin-6; Male; Middle Aged;

2006
Subclinical hypothyroidism is linked to micro-inflammation and predicts death in continuous ambulatory peritoneal dialysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:2

    Topics: Aged; C-Reactive Protein; Female; Humans; Hypothyroidism; Inflammation; Interleukin-6; Italy; Kidney

2007
The influence of experimental hypo- and hyperthyroid states on acute and chronic inflammatory reactions: modified response to non-steroidal anti-inflammatory agents.
    The Journal of pathology, 1981, Volume: 135, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Dose-Response Relationship, Drug; Edema;

1981
Influence of non-steroidal anti-inflammatory compounds on the hepatic tryptophan pyrrolase activity in hypo- and hyperthyroid rats.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 245, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Hyperthyroidism; Hypothyroidism; Inflammation; Liver; Male; Rats;

1980
Dexamethasone represses 3,5,3'-triiodothyronine-stimulated expression of intercellular adhesion molecule-1 in the human cell line ECV 304.
    Cell biology and toxicology, 1999, Volume: 15, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Cell Line; Dexamethasone; Gene Expr

1999
Inflammatory response, growth, and thyroid hormone concentrations are affected by long-term boron supplementation in gilts.
    Journal of animal science, 2001, Volume: 79, Issue:6

    Topics: Alkaline Phosphatase; Animal Husbandry; Animals; Borates; Boron; Cholesterol; Diet; Dietary Suppleme

2001
Does leptin modulate immune and endocrine response in the time of LPS-induced acute inflammation?
    Neuro endocrinology letters, 2001, Volume: 22, Issue:3

    Topics: Animals; Corticosterone; Cytokines; Hormones; Inflammation; Interleukin-10; Interleukin-6; Kinetics;

2001
Spontaneous recovery from hypopituitarism in a man with lymphocytic hypophysitis: a case report.
    Endocrine journal, 2001, Volume: 48, Issue:4

    Topics: Adrenocorticotropic Hormone; Hormone Replacement Therapy; Humans; Hydrocortisone; Hypopituitarism; I

2001
Rat corticotropin, insulin and thyroid hormone levels during the acute phase response to inflammation.
    Comparative biochemistry and physiology. A, Comparative physiology, 1987, Volume: 86, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Cells, Cultured; Inflammation; Insulin; Kinetics; Leukocytes;

1987
[Thyroid hormone and defense reactions].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Dec-15, Volume: 25, Issue:24

    Topics: Aged; Female; Humans; Inflammation; Male; Methylthiouracil; Neoplasms; Skin; Skin Window Technique;

1970
Influence of thyroidectomy and thyroid hormones on adjuvant arthritis in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Arthritis; Indomethacin; Inflammation; Male; Mycobacterium; Rats; S

1970
[Prevention of wound dehiscence].
    Zentralblatt fur Chirurgie, 1970, Sep-26, Volume: 95, Issue:39

    Topics: Humans; Inflammation; Lipopolysaccharides; Methods; Methylthiouracil; Skin; Skin Tests; Surgical Wou

1970