triiodothyronine has been researched along with Infection in 21 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Triiodothyronine treatment abolished the sepsis-induced decrease in free T3 levels (S = 68 +/- 5 ng/dL, CLP < 15 ng/dL, CLP/T3 = 91 +/- 20 ng/dL)." | 5.29 | Pulmonary biophysical effects of triiodothyronine augmentation during sepsis-induced hypothyroidism. ( Dulchavsky, SA; Dutta, S; Hendrick, SR, 1993) |
| "ātients with end-stage chronic renal failure (CRF) and those receiving dialysis therapy have normal or decreased serum total T4 (TT4), reduced serum total T3 (TT3), and normal total reverse T3 (TrT3) levels." | 5.27 | Alterations of serum reverse triiodothyronine and thyroxine kinetics in chronic renal failure: role of nutritional status, chronic illness, uremia, and hemodialysis. ( Feinstein, EI; Kaptein, EM; Massry, SG; Nicoloff, JT, 1983) |
| "Triiodothyronine treatment abolished the sepsis-induced decrease in free T3 levels (S = 68 +/- 5 ng/dL, CLP < 15 ng/dL, CLP/T3 = 91 +/- 20 ng/dL)." | 1.29 | Pulmonary biophysical effects of triiodothyronine augmentation during sepsis-induced hypothyroidism. ( Dulchavsky, SA; Dutta, S; Hendrick, SR, 1993) |
| "In the follow-up of patients with Kawasaki disease, a marked inverse relationship was observed between serum IL-6 and T3 (r = -0." | 1.29 | The relationship between serum levels of interleukin-6 and thyroid hormone during the follow-up study in children with nonthyroidal illness: marked inverse correlation in Kawasaki and infectious disease. ( Hashimoto, H; Hashimoto, T; Igarashi, N; Miyawaki, T; Sato, T; Yachie, A, 1996) |
| "ātients with end-stage chronic renal failure (CRF) and those receiving dialysis therapy have normal or decreased serum total T4 (TT4), reduced serum total T3 (TT3), and normal total reverse T3 (TrT3) levels." | 1.27 | Alterations of serum reverse triiodothyronine and thyroxine kinetics in chronic renal failure: role of nutritional status, chronic illness, uremia, and hemodialysis. ( Feinstein, EI; Kaptein, EM; Massry, SG; Nicoloff, JT, 1983) |
| "Infection is a frequent cause of death in patients receiving bone marrow transplants." | 1.26 | Defective neutrophil chemotaxis in bone marrow transplant patients. ( Clark, RA; Johnson, FL; Klebanoff, SJ; Thomas, ED, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (57.14) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Onishi, KG | 1 |
| Prendergast, BJ | 1 |
| Stevenson, TJ | 1 |
| Boelen, A | 1 |
| Kwakkel, J | 1 |
| Fliers, E | 1 |
| MURPHY, WH | 1 |
| WIENS, AL | 1 |
| WATSON, DW | 1 |
| NUTTER, JE | 1 |
| GEMMILL, CL | 1 |
| MYRVIK, QN | 1 |
| Lechan, RM | 1 |
| Fekete, C | 1 |
| Kaptein, EM | 2 |
| Feinstein, EI | 1 |
| Nicoloff, JT | 2 |
| Massry, SG | 1 |
| Robinson, WJ | 1 |
| Grieb, DA | 1 |
| Dulchavsky, SA | 4 |
| Hendrick, SR | 1 |
| Dutta, S | 1 |
| Hashimoto, H | 1 |
| Igarashi, N | 1 |
| Yachie, A | 1 |
| Miyawaki, T | 1 |
| Hashimoto, T | 1 |
| Sato, T | 1 |
| Ksenzenko, SM | 1 |
| Davidson, SB | 1 |
| Saba, AA | 1 |
| Franko, AP | 1 |
| Raafat, AM | 1 |
| Diebel, LN | 1 |
| Stathatos, N | 1 |
| Levetan, C | 1 |
| Burman, KD | 1 |
| Wartofsky, L | 1 |
| Helenius, T | 1 |
| Liewendahl, K | 1 |
| Gavin, LA | 1 |
| Rosenthal, M | 1 |
| Cavalieri, RR | 1 |
| Clark, RA | 1 |
| Johnson, FL | 1 |
| Klebanoff, SJ | 1 |
| Thomas, ED | 1 |
| Bailey, J | 1 |
| Kennedy, PR | 1 |
| Geller, ER | 1 |
| Maitra, SR | 1 |
| Foster, WM | 1 |
| Langenbeck, EG | 1 |
| Franklin, R | 1 |
| O'Grady, C | 1 |
| Alexander, WD | 1 |
| Harden, RM | 1 |
| Shimmins, J | 1 |
| Inada, M | 1 |
| Green, D | 1 |
| Smith, NJ | 1 |
| Blum, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Effects of N-acetylcysteine on Thyroid Hormone Levels in the Low T3 Syndrome[NCT01501110] | Phase 4 | 83 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01501110)
Timeframe: 48 hours
| Intervention | ng/dL (Mean) |
|---|---|
| N-acetylcysteine | 93.5 |
| no Intervention | 96.5 |
6 reviews available for triiodothyronine and Infection
| Article | Year |
|---|---|
Beyond low plasma T3: local thyroid hormone metabolism during inflammation and infection.
Topics: Acute Disease; Adipose Tissue; Bacterial Infections; Chronic Disease; Euthyroid Sick Syndromes; Gene | 2011 |
Role of thyroid hormone deiodination in the hypothalamus.
Topics: Animals; Appetite; Brain; Cachexia; Fasting; Gene Expression Regulation, Developmental; Humans; Hypo | 2005 |
The controversy of the treatment of critically ill patients with thyroid hormone.
Topics: Animals; Critical Care; Critical Illness; Heart Diseases; Humans; Infections; Respiration; Shock; Th | 2001 |
[Thyroxine binding protein, free thyroxine and triiodothyronine--interpretation of the test results].
Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Child; Diabetes Mellitus; Female; Humans; Infectio | 1973 |
Hemophilia. Current concepts in management.
Topics: Adrenal Cortex Hormones; Adult; Analgesics; Antifibrinolytic Agents; Blood Transfusion; Cardiovascul | 1972 |
Myxedema coma.
Topics: Adrenal Glands; Cachexia; Central Nervous System; Coma; Heart Diseases; Humans; Hypoglycemia; Hypona | 1972 |
15 other studies available for triiodothyronine and Infection
| Article | Year |
|---|---|
Trait-specific effects of exogenous triiodothyronine on cytokine and behavioral responses to simulated systemic infection in male Siberian hamsters.
Topics: Animals; Anorexia; Behavior, Animal; Body Weight; Cricetinae; Cytokines; Disease Models, Animal; Hyp | 2019 |
Impairment of innate resistance by triiodothyronine.
Topics: Biochemical Phenomena; Humans; Infections; Triiodothyronine | 1958 |
The influence of 3,3',5-triiodo-L-thyronine on the survival time of mice with tuberculosis and pneumococcosis.
Topics: Animals; Infections; Mice; Pneumococcal Infections; Streptococcus pneumoniae; Thyronines; Triiodothy | 1959 |
Alterations of serum reverse triiodothyronine and thyroxine kinetics in chronic renal failure: role of nutritional status, chronic illness, uremia, and hemodialysis.
Topics: Adult; Aged; Body Weight; Chronic Disease; Female; Humans; Infections; Kidney Failure, Chronic; Kine | 1983 |
Peripheral serum thyroxine, triiodothyronine and reverse triiodothyronine kinetics in the low thyroxine state of acute nonthyroidal illnesses. A noncompartmental analysis.
Topics: Acute Disease; Adult; Aged; Binding Sites; Female; Humans; Infections; Kinetics; Liver Diseases; Mal | 1982 |
Pulmonary biophysical effects of triiodothyronine augmentation during sepsis-induced hypothyroidism.
Topics: Animals; Hypothyroidism; Infections; Lung; Lung Compliance; Male; Pulmonary Gas Exchange; Rats; Rats | 1993 |
The relationship between serum levels of interleukin-6 and thyroid hormone during the follow-up study in children with nonthyroidal illness: marked inverse correlation in Kawasaki and infectious disease.
Topics: Adolescent; Child; Child, Preschool; Humans; Infant; Infections; Interleukin-6; Mucocutaneous Lymph | 1996 |
Effect of triiodothyronine augmentation on rat lung surfactant phospholipids during sepsis.
Topics: Animals; Fatty Acids; Infections; Lung; Lung Compliance; Lung Diseases; Male; Phospholipids; Pulmona | 1997 |
Abnormal thyroid function tests in devere non-thyroidal illness: diagnostic and pathophysiologic aspects.
Topics: Adult; Aged; Cardiovascular Diseases; Fatty Acids, Nonesterified; Female; Gastrointestinal Diseases; | 1979 |
The diagnostic dilemma of isolated hyperthyroxinemia in acute illness.
Topics: Acute Disease; Aged; Asthma; Carcinoma, Bronchogenic; Female; Heart Diseases; Humans; Infections; Li | 1979 |
Defective neutrophil chemotaxis in bone marrow transplant patients.
Topics: Acute Disease; Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Bone Ma | 1976 |
Triiodothyronine treatment maintains surfactant synthesis during sepsis.
Topics: Animals; Cecum; Infections; Ligation; Lung; Male; Phospholipids; Pulmonary Alveoli; Pulmonary Surfac | 1992 |
T3 preserves respiratory function in sepsis.
Topics: Airway Resistance; Animals; Hypothyroidism; Infections; Lung; Lung Compliance; Male; Organ Size; Rat | 1991 |
Neonatal thyroid function: effects of nonthyroidal illness.
Topics: Asphyxia Neonatorum; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Infections; M | 1985 |
Emotion and non-specific infection as possible aetiological factors in Graves' disease. Their relation to thyroid suppressibility.
Topics: Adult; Antithyroid Agents; Emotions; Female; Graves Disease; Humans; Hyperthyroidism; Infections; Ma | 1968 |