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triiodothyronine and Infarction, Middle Cerebral Artery

triiodothyronine has been researched along with Infarction, Middle Cerebral Artery in 4 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.

Research Excerpts

ExcerptRelevanceReference
" This study was designed to evaluate the effects of retinoic acid (RA)-pretreated Wharton's jelly mesenchymal stem cells (WJ-MSCs) in combination with triiodothyronine (T3) in the ischemia stroke model."1.46Retinoic acid-pretreated Wharton's jelly mesenchymal stem cells in combination with triiodothyronine improve expression of neurotrophic factors in the subventricular zone of the rat ischemic brain injury. ( Akbari, M; Ataeinejad, N; Hassanzadeh, G; Kashani, IR; Moini, A; Mortezaee, K; Sabbaghziarani, F; Soleimani, M; Zendedel, A, 2017)
"Cerebral ischemia was induced by middle cerebral artery occlusion in male Wistar rats."1.46Stimulation of neurotrophic factors and inhibition of proinflammatory cytokines by exogenous application of triiodothyronine in the rat model of ischemic stroke. ( Akbari, M; Hassanzadeh, G; Kashani, IR; Mortezaee, K; Sabbaghziarani, F; Soleimani, M; Zendedel, A, 2017)
"Ischemic stroke is a common leading cause of death and disability with lack of effective therapies."1.46Improvement of memory and learning by intracerebroventricular microinjection of T3 in rat model of ischemic brain stroke mediated by upregulation of BDNF and GDNF in CA1 hippocampal region. ( Akbari, M; Attari, F; Ghazi-Khansari, M; Hassanzadeh, G; Kashani, IR; Malek, F; Mokhtari, T; Noorbakhsh, F; Rastegar, T, 2017)
"We have used both transient middle cerebral artery occlusion (t-MCAO) and permanent (p-MCAO) models of ischemic brain stroke."1.42Anti-edema action of thyroid hormone in MCAO model of ischemic brain stroke: Possible association with AQP4 modulation. ( Burke, J; Coughlin, L; Mdzinarishvili, A; Sadana, P; Woods, R, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sadana, P1
Coughlin, L1
Burke, J1
Woods, R1
Mdzinarishvili, A1
Sabbaghziarani, F2
Mortezaee, K2
Akbari, M3
Kashani, IR3
Soleimani, M2
Moini, A1
Ataeinejad, N1
Zendedel, A2
Hassanzadeh, G3
Mokhtari, T1
Malek, F1
Rastegar, T1
Noorbakhsh, F1
Ghazi-Khansari, M1
Attari, F1

Other Studies

4 other studies available for triiodothyronine and Infarction, Middle Cerebral Artery

ArticleYear
Anti-edema action of thyroid hormone in MCAO model of ischemic brain stroke: Possible association with AQP4 modulation.
    Journal of the neurological sciences, 2015, Jul-15, Volume: 354, Issue:1-2

    Topics: Animals; Aquaporin 4; Brain Edema; Cerebrovascular Circulation; Diiodothyronines; Infarction, Middle

2015
Retinoic acid-pretreated Wharton's jelly mesenchymal stem cells in combination with triiodothyronine improve expression of neurotrophic factors in the subventricular zone of the rat ischemic brain injury.
    Metabolic brain disease, 2017, Volume: 32, Issue:1

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cytokines; Disease Models, Animal; Infarction, Middle Ce

2017
Stimulation of neurotrophic factors and inhibition of proinflammatory cytokines by exogenous application of triiodothyronine in the rat model of ischemic stroke.
    Cell biochemistry and function, 2017, Volume: 35, Issue:1

    Topics: Animals; Blotting, Western; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cytokines; Disease Mo

2017
Improvement of memory and learning by intracerebroventricular microinjection of T3 in rat model of ischemic brain stroke mediated by upregulation of BDNF and GDNF in CA1 hippocampal region.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2017, Feb-15, Volume: 25, Issue:1

    Topics: Animals; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal;

2017