triiodothyronine has been researched along with Infant, Premature, Diseases in 24 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Infant, Premature, Diseases: Diseases that occur in PREMATURE INFANTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypothyroidism was diagnosed in 6 of the 8 preterm and in 1 of the 7 term newborns of group 2." | 5.27 | Iodine in contrast agents and skin disinfectants is the major cause for hypothyroidism in premature infants during intensive care. ( Beyer, P; Grüters, A; l'Allemand, D; Weber, B, 1987) |
| " The cord separation time, gender, mode of delivery, presence of sepsis, duration of antibiotic treatment, serum free thyroxine, free triiodothyronine (FT3), thyroid-stimulating hormone, lowest leukocyte, polymorphonuclear leukocytes (PMNLs), and platelet counts were recorded." | 4.12 | Umbilical Cord Separation Time and Influencing Factors in Very-Low-Birth-Weight Preterm Neonates. ( Arslan, Z; Bas, AY; Demirel, N; Tokgoz-Cuni, B; Ulubas-Isik, D; Unal, S, 2022) |
| "Premature newborns are particularly vulnerable to iatrogenic hypothyroidism due to iodine exposure, usually through skin absorption of iodine-containing disinfectants or intravenous administration of iodinated contrast agents." | 3.75 | Severe hypothyroidism after contrast enema in premature infants. ( Cambonie, G; Dalla-Vale, F; Lombard, F; Picaud, JC; Plan, O; Veyrac, C, 2009) |
| "The authors report eight preterm infants with hypothyroxinemia who developed clinical features similar to those described in congenital hypothyroidism: prolonged jaundice, hypoactivity, lethargy, constipation, edema, and hoarse cry." | 3.67 | Symptomatic hypothyroxinemia with normal TSH levels in preterm infants. ( Gold, H; Mercado, M; Szymonowicz, W; Yu, VY, 1987) |
| "Hypothyroidism was diagnosed in 6 of the 8 preterm and in 1 of the 7 term newborns of group 2." | 1.27 | Iodine in contrast agents and skin disinfectants is the major cause for hypothyroidism in premature infants during intensive care. ( Beyer, P; Grüters, A; l'Allemand, D; Weber, B, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (50.00) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Unal, S | 1 |
| Demirel, N | 1 |
| Arslan, Z | 1 |
| Tokgoz-Cuni, B | 1 |
| Ulubas-Isik, D | 1 |
| Bas, AY | 1 |
| Miao, KF | 1 |
| Duan, W | 1 |
| Qian, Y | 1 |
| Chen, DQ | 1 |
| Lombard, F | 1 |
| Dalla-Vale, F | 1 |
| Veyrac, C | 1 |
| Plan, O | 1 |
| Cambonie, G | 1 |
| Picaud, JC | 1 |
| Simic, N | 1 |
| Asztalos, EV | 1 |
| Rovet, J | 1 |
| Shih, JL | 1 |
| Agus, MS | 1 |
| La Gamma, EF | 1 |
| van Wassenaer, AG | 1 |
| Ares, S | 1 |
| Golombek, SG | 1 |
| Kok, JH | 1 |
| Quero, J | 1 |
| Hong, T | 1 |
| Rahbar, MH | 1 |
| de Escobar, GM | 1 |
| Fisher, DA | 3 |
| Paneth, N | 1 |
| Hemmati, F | 1 |
| Pishva, N | 1 |
| Osborn, DA | 1 |
| Hunt, RW | 1 |
| Grimm, V | 1 |
| Homoki, J | 1 |
| Loos, U | 1 |
| Gaus, W | 1 |
| Teller, WM | 1 |
| Delange, F | 2 |
| Dalhem, A | 2 |
| Bourdoux, P | 2 |
| Lagasse, R | 1 |
| Glinoer, D | 2 |
| Walfish, PG | 1 |
| Ermans, AM | 2 |
| Eggermont, E | 1 |
| Vanderschueren-Lodeweyckx, M | 1 |
| De Nayer, P | 1 |
| Smeets, E | 1 |
| Vanacker, G | 1 |
| Cornette, C | 1 |
| Jaeken, J | 1 |
| Devlieger, H | 1 |
| Eeckels, R | 1 |
| Beckers, C | 1 |
| Schönberger, W | 2 |
| Grimm, W | 2 |
| Emmrich, P | 2 |
| Gempp, W | 2 |
| Rapaport, R | 1 |
| Sills, I | 1 |
| Patel, U | 1 |
| Oppenheimer, E | 1 |
| Skuza, K | 1 |
| Horlick, M | 1 |
| Goldstein, S | 1 |
| Dimartino, J | 1 |
| Saenger, P | 1 |
| Ballard, PL | 1 |
| Ballard, RA | 1 |
| Ning, Y | 1 |
| Cnann, A | 1 |
| Boardman, C | 1 |
| Pinto-Martin, J | 1 |
| Polk, D | 1 |
| Phibbs, RH | 1 |
| Davis, DJ | 1 |
| Mannino, FL | 1 |
| Hart, M | 1 |
| Biswas, S | 1 |
| Buffery, J | 1 |
| Enoch, H | 1 |
| Bland, JM | 1 |
| Walters, D | 1 |
| Markiewicz, M | 1 |
| Jacobsen, BB | 2 |
| Peitersen, B | 2 |
| Hummer, L | 2 |
| Dodion, J | 1 |
| Wolter, R | 1 |
| Amato, M | 1 |
| Guggisberg, C | 1 |
| Schneider, H | 1 |
| Mercado, M | 1 |
| Szymonowicz, W | 1 |
| Yu, VY | 1 |
| Gold, H | 1 |
| l'Allemand, D | 1 |
| Grüters, A | 1 |
| Beyer, P | 1 |
| Weber, B | 1 |
| John, R | 1 |
| Bamforth, FJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase III Study of Thyroid Hormones in Prematures[NCT02103998] | Phase 3 | 0 participants (Actual) | Interventional | 2020-07-01 | Withdrawn (stopped due to not funded by NIH) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for triiodothyronine and Infant, Premature, Diseases
| Article | Year |
|---|---|
Thyroid function in the critically ill newborn and child.
Topics: Animals; Cardiac Surgical Procedures; Child; Child, Preschool; Critical Illness; Humans; Hypothyroid | 2009 |
Prophylactic postnatal thyroid hormones for prevention of morbidity and mortality in preterm infants.
Topics: Developmental Disabilities; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; | 2007 |
Increased risk of primary hypothyroidism in preterm infants.
Topics: Belgium; Female; Humans; Hypothyroidism; Infant, Newborn; Infant, Premature, Diseases; Iodine; Longi | 1984 |
Euthyroid low thyroxine (T4) and triiodothyronine (T3) states in prematures and sick neonates.
Topics: Embryonic and Fetal Development; Euthyroid Sick Syndromes; Fetal Blood; Humans; Infant, Newborn; Inf | 1990 |
5 trials available for triiodothyronine and Infant, Premature, Diseases
| Article | Year |
|---|---|
Phase 1 trial of 4 thyroid hormone regimens for transient hypothyroxinemia in neonates of <28 weeks' gestation.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up | 2009 |
Plasma thyroid hormones in premature infants: effect of gestational age and antenatal thyrotropin-releasing hormone treatment. TRH Collaborative Trial Participants.
Topics: Congenital Hypothyroidism; Gestational Age; Humans; Hypothyroidism; Infant, Newborn; Infant, Prematu | 1998 |
A longitudinal assessment of thyroid hormone concentrations in preterm infants younger than 30 weeks' gestation during the first 2 weeks of life and their relationship to outcome.
Topics: Age Factors; Double-Blind Method; Female; Gestational Age; Humans; Hydrocortisone; Infant, Newborn; | 2002 |
Thyroid administration lowers mortality in premature infants.
Topics: Humans; Hypothyroidism; Infant, Newborn; Infant, Premature, Diseases; Thyroxine; Triiodothyronine | 1979 |
Postnatal triiodothyronine replacement and respiratory distress syndrome of the preterm infant.
Topics: Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Lung; Male; Pregnancy; Pulmonary Surfa | 1989 |
15 other studies available for triiodothyronine and Infant, Premature, Diseases
| Article | Year |
|---|---|
Umbilical Cord Separation Time and Influencing Factors in Very-Low-Birth-Weight Preterm Neonates.
Topics: Anti-Bacterial Agents; Birth Weight; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Prema | 2022 |
[Analysis of influencing factors of transient hypothyroxinemia and low T3 syndrome in premature infants].
Topics: Case-Control Studies; Dopamine; Euthyroid Sick Syndromes; Female; Gestational Age; Humans; Hypothyro | 2013 |
Severe hypothyroidism after contrast enema in premature infants.
Topics: Cholestasis; Contrast Media; Enema; Goiter; Humans; Hypothyroidism; Iatrogenic Disease; Infant, Extr | 2009 |
Impact of neonatal thyroid hormone insufficiency and medical morbidity on infant neurodevelopment and attention following preterm birth.
Topics: Attention Deficit Disorder with Hyperactivity; Child Development; Developmental Disabilities; Humans | 2009 |
Evaluation of thyroid status of infants in the intensive care setting.
Topics: Body Weight; Cohort Studies; Euthyroid Sick Syndromes; Humans; Infant, Newborn; Infant, Premature, D | 2009 |
[Thyroid function in premature infants of different gestational age during the first month of life (author's transl)].
Topics: Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Thyroid Gland; Thyrotropin; | 1980 |
The thyroid-system function in preterm infants of postmenstrual ages of 31 weeks or less: evidence for a "transient lazy thyroid system".
Topics: Age Factors; Failure to Thrive; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Disease | 1984 |
Reduction of mortality rate in premature infants by substitution of thyroid hormones.
Topics: Female; Germany, West; Humans; Hypothyroidism; Infant Mortality; Infant, Newborn; Infant, Premature; | 1981 |
Thyrotropin-releasing hormone stimulation tests in infants.
Topics: Congenital Hypothyroidism; Follow-Up Studies; Humans; Hypothyroidism; Infant; Infant, Newborn; Infan | 1993 |
Serum concentrations of thyrotropin, thyroid hormones and thyroid hormone-binding proteins during acute and recovery stages of idiopathic respiratory distress syndrome.
Topics: Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Prealbumin; Protein Binding | 1979 |
"Transient hypothyroidism" in premature infants.
Topics: Humans; Hypothyroidism; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Thyrotropin | 1979 |
Transient hypothyroidism in the newborn infant.
Topics: Congenital Hypothyroidism; Female; Follow-Up Studies; Humans; Hypothyroidism; Infant, Newborn; Infan | 1978 |
Symptomatic hypothyroxinemia with normal TSH levels in preterm infants.
Topics: Humans; Hypothyroidism; Immunoglobulin G; Immunoglobulins, Thyroid-Stimulating; Infant, Newborn; Inf | 1987 |
Iodine in contrast agents and skin disinfectants is the major cause for hypothyroidism in premature infants during intensive care.
Topics: Contrast Media; Critical Care; Disinfectants; Humans; Hypothyroidism; Infant, Newborn; Infant, Prema | 1987 |
Serum free thyroxine and free triiodothyronine concentrations in healthy fullterm, preterm and sick preterm neonates.
Topics: Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Reference Val | 1987 |