triiodothyronine has been researched along with Inadequate Sleep in 25 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " What is the main finding and its importance? Central hypothyroidism and high thyroxine (T4 ) to 3,5,3'-triiodothyronine (T3 ) activation in brown adipose tissue were observed following sleep deprivation." | 3.81 | Sleep deprivation alters thyroid hormone economy in rats. ( da Conceição, RR; da Cruz, NS; da Silva, AC; de Paula Nascimento, C; Marassi, MP; Olivares, EL; Rodrigues, NC, 2015) |
| "Thyrotropin (TSH), thyroxine (T4), free T4, triiodothyronine (T3), and free T3 (fT3) concentrations were measured in 25 patients with major depressive disorder at 8 a." | 3.68 | Thyrotropin (TSH) and thyroid hormone concentrations during partial sleep deprivation in patients with major depressive disorder. ( Baumgartner, A; Gräf, KJ; Kürten, I; Meinhold, H, 1990) |
| "The literature suggests that sleep deprivation can potentiate the effect of antidepressant medication in depressed patients." | 2.67 | A clinical trial of sleep deprivation in combination with antidepressant medication. ( Leibenluft, E; Madden, PA; Moul, DE; Schwartz, PJ; Wehr, TA, 1993) |
| "Total sleep deprivation (TSD) exerts strong modulatory effects on the secretory activity of endocrine systems that might be related to TSD-induced challenges of cerebral glucose metabolism." | 1.39 | Pituitary-gonadal and pituitary-thyroid axis hormone concentrations before and during a hypoglycemic clamp after sleep deprivation in healthy men. ( Hallschmid, M; Jauch-Chara, K; Oltmanns, KM; Schmid, SM; Schultes, B, 2013) |
| "Rapid eye movement sleep deprivation of rats were deprived by flower pot, and then the energy metabolism were detected." | 1.36 | [The effects of chronic rapid eye movement sleep deprivation on energy metabolism and FT3, FT4 level in serum of rats]. ( Shao, SL; Si, DL; Xu, XJ; Zeng, R; Zhang, WW, 2010) |
| "Sustained sleep deprivation resulted in a decline from baseline in plasma FT4 of 73 +/- 6% and FT3 of 45 +/- 12%, which were similar to the declines in total hormone concentrations observed previously; nonstimulated TSH was unchanged." | 1.29 | Pituitary and peripheral thyroid hormone responses to thyrotropin-releasing hormone during sustained sleep deprivation in freely moving rats. ( Everson, CA; Reed, HL, 1995) |
| "The effects of 24 h sleep deprivation (SD) on central thyroid hormone metabolism were investigated in rat frontal cortex." | 1.29 | The influence of sleep deprivation on thyroid hormone metabolism in rat frontal cortex. ( Baumgartner, A; Campos-Barros, A; Eravci, M; Köhler, R; Meinhold, H; Müller, F; Wesemann, W, 1993) |
| "As expected, sleep deprivation was associated with elevated TSH." | 1.29 | Total sleep deprivation and the thyroid axis: effects of sleep and waking activity. ( Dinges, DF; Douglas, SD; Gary, KA; Kapoor, S; Winokur, A; Zaugg, L, 1996) |
| "The results suggest that sleep deprivation provokes enhanced secretion of thyroid hormone(s), supposedly via increased secretion of TSH." | 1.26 | Thyroid and adrenomedullary reactions during sleep deprivation. ( Akerstedt, T; Fröberg, J; Melander, A; Palmblad, J; von Schenck, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (28.00) | 18.7374 |
| 1990's | 10 (40.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmid, SM | 2 |
| Hallschmid, M | 2 |
| Jauch-Chara, K | 2 |
| Kück, MC | 1 |
| Lehnert, H | 1 |
| Schultes, B | 2 |
| Aydin, A | 1 |
| Selvi, Y | 1 |
| Besiroglu, L | 1 |
| Boysan, M | 1 |
| Atli, A | 1 |
| Ozdemir, O | 1 |
| Kilic, S | 1 |
| Balaharoglu, R | 1 |
| Zhang, N | 1 |
| Ma, Q | 1 |
| Chen, XW | 1 |
| Xu, CX | 1 |
| An, GH | 1 |
| Cui, B | 1 |
| She, XJ | 1 |
| Rodrigues, NC | 1 |
| da Cruz, NS | 1 |
| de Paula Nascimento, C | 1 |
| da Conceição, RR | 1 |
| da Silva, AC | 1 |
| Olivares, EL | 1 |
| Marassi, MP | 1 |
| Zeng, R | 1 |
| Shao, SL | 1 |
| Xu, XJ | 1 |
| Zhang, WW | 1 |
| Si, DL | 1 |
| Oltmanns, KM | 1 |
| Gelir, E | 1 |
| Arslan, SO | 1 |
| Sayan, H | 1 |
| Pinar, L | 1 |
| Sulser, F | 1 |
| Opstad, PK | 3 |
| Falch, D | 1 |
| Oktedalen, O | 1 |
| Fonnum, F | 2 |
| Wergeland, R | 1 |
| Aakvaag, A | 2 |
| Everson, CA | 3 |
| Reed, HL | 1 |
| Goichot, B | 1 |
| Brandenberger, G | 1 |
| Saini, J | 1 |
| Wittersheim, G | 1 |
| Follenius, M | 1 |
| Campos-Barros, A | 1 |
| Köhler, R | 1 |
| Müller, F | 1 |
| Eravci, M | 1 |
| Meinhold, H | 3 |
| Wesemann, W | 1 |
| Baumgartner, A | 3 |
| Leibenluft, E | 1 |
| Moul, DE | 1 |
| Schwartz, PJ | 1 |
| Madden, PA | 1 |
| Wehr, TA | 1 |
| Gary, KA | 1 |
| Winokur, A | 1 |
| Douglas, SD | 1 |
| Kapoor, S | 1 |
| Zaugg, L | 1 |
| Dinges, DF | 1 |
| Parekh, PI | 1 |
| Ketter, TA | 1 |
| Altshuler, L | 1 |
| Frye, MA | 1 |
| Callahan, A | 1 |
| Marangell, L | 1 |
| Post, RM | 1 |
| Nowak, TS | 1 |
| Palmblad, J | 1 |
| Akerstedt, T | 1 |
| Fröberg, J | 1 |
| Melander, A | 1 |
| von Schenck, H | 1 |
| Sand, T | 1 |
| Szuba, MP | 1 |
| Altshuler, LL | 1 |
| Baxter, LR | 1 |
| Pilcher, JJ | 1 |
| Bergmann, BM | 2 |
| Refetoff, S | 2 |
| Fang, VS | 2 |
| Rechtschaffen, A | 2 |
| Gräf, KJ | 1 |
| Kürten, I | 1 |
| Sakaue, K | 1 |
| Kushida, CA | 1 |
| Leitch, CA | 1 |
| Schoeller, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| AgeWise Project 2: Reducing Stress and Sleep Disturbances in Caregivers of Patients With Progressive Dementia[NCT00178568] | 60 participants (Actual) | Observational | 2003-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for triiodothyronine and Inadequate Sleep
| Article | Year |
|---|---|
Antidepressant treatments and regulation of norepinephrine-receptor-coupled adenylate cyclase systems in brain.
Topics: Adenylyl Cyclases; Adrenal Cortex Hormones; Animals; Antidepressive Agents; Brain; Brain Chemistry; | 1984 |
4 trials available for triiodothyronine and Inadequate Sleep
| Article | Year |
|---|---|
Partial sleep restriction modulates secretory activity of thyrotropic axis in healthy men.
Topics: Adult; Cross-Over Studies; Humans; Male; Sleep Deprivation; Thyroid Gland; Thyrotropin; Thyroxine; T | 2013 |
The thyroid function in young men during prolonged exercise and the effect of energy and sleep deprivation.
Topics: Adult; Body Weight; Energy Intake; Energy Metabolism; Humans; Male; Physical Exertion; Sleep Depriva | 1984 |
A clinical trial of sleep deprivation in combination with antidepressant medication.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Body Temperature Regulation; Circadian Rhythm; Combi | 1993 |
Relationships between thyroid hormone and antidepressant responses to total sleep deprivation in mood disorder patients.
Topics: Adult; Depressive Disorder; Female; Humans; Male; Mood Disorders; Psychiatric Status Rating Scales; | 1998 |
20 other studies available for triiodothyronine and Inadequate Sleep
| Article | Year |
|---|---|
Mood and metabolic consequences of sleep deprivation as a potential endophenotype' in bipolar disorder.
Topics: Adult; Affect; Bipolar Disorder; Case-Control Studies; Circadian Rhythm; Dehydroepiandrosterone; End | 2013 |
[Effects of retinol acid and triiodothyronine on alleviating the impairment of cognitive function by sleep deprivation].
Topics: Animals; Cognition; Dentate Gyrus; Long-Term Potentiation; Male; Neurogranin; Rats; Rats, Wistar; Sl | 2013 |
Sleep deprivation alters thyroid hormone economy in rats.
Topics: Animals; Hypothalamo-Hypophyseal System; Hypothyroidism; Male; Rats; Rats, Wistar; Sleep Deprivation | 2015 |
[The effects of chronic rapid eye movement sleep deprivation on energy metabolism and FT3, FT4 level in serum of rats].
Topics: Animals; Energy Metabolism; Male; Rats; Rats, Wistar; Sleep Deprivation; Sleep, REM; Thyroxine; Time | 2010 |
Pituitary-gonadal and pituitary-thyroid axis hormone concentrations before and during a hypoglycemic clamp after sleep deprivation in healthy men.
Topics: Adult; Gonads; Humans; Hypoglycemia; Male; Pituitary Gland; Prolactin; Sleep Deprivation; Testostero | 2013 |
Effect of rapid-eye-movement sleep deprivation on rat hypothalamic prostaglandins.
Topics: Animals; Body Weight; Dinoprostone; Hypothalamus; Male; Prostaglandin D2; Prostaglandins; Rats; Rats | 2005 |
The effect of a high calory diet on hormonal changes in young men during prolonged physical strain and sleep deprivation.
Topics: Adult; Diet; Energy Intake; Growth Hormone; Hormones; Humans; Hydrocortisone; Insulin; Male; Physica | 1981 |
Pituitary and peripheral thyroid hormone responses to thyrotropin-releasing hormone during sustained sleep deprivation in freely moving rats.
Topics: Adipose Tissue, Brown; Animals; Iodide Peroxidase; Male; Pituitary Gland; Rats; Rats, Sprague-Dawley | 1995 |
Nycthemeral patterns of thyroid hormones and their relationships with thyrotropin variations and sleep structure.
Topics: Adult; Enteral Nutrition; Humans; Male; Polysomnography; Sleep; Sleep Deprivation; Sleep Stages; Thy | 1994 |
The influence of sleep deprivation on thyroid hormone metabolism in rat frontal cortex.
Topics: Animals; Iodide Peroxidase; Isoenzymes; Male; Nerve Tissue Proteins; Prefrontal Cortex; Rats; Rats, | 1993 |
Total sleep deprivation and the thyroid axis: effects of sleep and waking activity.
Topics: Adult; Female; Humans; Hypothalamo-Hypophyseal System; Male; Sleep Deprivation; Thyroid Gland; Thyro | 1996 |
Hypothalamic thyrotropin-releasing hormone mRNA responses to hypothyroxinemia induced by sleep deprivation.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Hypothalamus; In Situ Hybridization; Iodide Peroxidase; Io | 2002 |
Thyroid and adrenomedullary reactions during sleep deprivation.
Topics: Adrenal Medulla; Adult; Epinephrine; Humans; Male; Norepinephrine; Sleep Deprivation; Thyroid Gland; | 1979 |
Hormonal changes in serum in young men during prolonged physical strain.
Topics: Follicle Stimulating Hormone; Growth Hormone; Luteinizing Hormone; Military Medicine; Norway; Prolac | 1978 |
Thyroid function and partial sleep deprivation response.
Topics: Adolescent; Adult; Aged; Arousal; Depressive Disorder; Female; Humans; Male; Middle Aged; Sleep Depr | 1992 |
Sleep deprivation in the rat: XIII. The effect of hypothyroidism on sleep deprivation symptoms.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Circadian Rhythm; Energy Metabolism; Ep | 1991 |
Thyrotropin (TSH) and thyroid hormone concentrations during partial sleep deprivation in patients with major depressive disorder.
Topics: Adult; Aged; Arousal; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Slee | 1990 |
[Studies on the factors affecting serum thyrotropin levels in healthy controls and on the thyroid function in depressed patients using a highly sensitive immunoassay].
Topics: Adult; Aged; Circadian Rhythm; Depression; Female; Fluoroimmunoassay; Humans; Male; Middle Aged; Ref | 1990 |
Sleep deprivation in the rat: V. Energy use and mediation.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Arousal; Body Temperature Regulation; | 1989 |
Sleep deprivation and thyroid hormone concentrations.
Topics: Adult; Aged; Depressive Disorder; Female; Humans; Male; Middle Aged; Sleep Deprivation; Thyrotropin; | 1986 |