triiodothyronine has been researched along with Hypoxia in 50 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
Excerpt | Relevance | Reference |
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"Factors affecting halothane (H) hepatotoxicity were investigated in two animal models: 1) the phenobarbital-hypoxia model, and 2) the triiodothyronine (T3) model; in the latter we previously have shown that centrilobular necrosis occurs in T3 pretreated rats anesthetized with 1% H, in 21% oxygen for 2 h." | 7.66 | Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications. ( Phythyon, JM; Uetrecht, J; Wood, AJ; Wood, M, 1983) |
" These include increased activity of the GH/IGF-I axis and a low T(3) syndrome but no change in ghrelin and leptin that was expected taking into account body weight decrease." | 3.74 | Endocrine and metabolic responses to extreme altitude and physical exercise in climbers. ( Aimaretti, G; Benso, A; Broglio, F; Ghigo, E; Grottoli, S; Lanfranco, F; Lucatello, B, 2007) |
"In the present work, we studied the effects of hypoxia and triiodothyronine (T(3)) on phosphoglycerate mutase (PGAM) activity and expression in rabbit liver, brain, and skeletal muscle under in vivo conditions." | 3.72 | Effects of hypoxia and thyroid hormone on mRNA levels and activity of phosphoglycerate mutase in rabbit tissues. ( Carreras, J; Climent, F; González-Cinca, N; Rivera, F, 2003) |
"The effects of triiodothyronine (T(3)) and hypoxia on 2,3-bisphosphoglycerate (2,3-BPG) studied in vitro are unclear." | 3.72 | Effects of thyroid hormone and hypoxia on 2,3-bisphosphoglycerate, bisphosphoglycerate synthase and phosphoglycerate mutase in rabbit erythroblasts and reticulocytes in vivo. ( Carreras, J; Climent, F; González-Cinca, N; Pérez de la Ossa, P, 2004) |
" L-triiodothyronine and L-thyroxine stimulated hypoxia-induced Epo formation both in the kidney and in HepG2 cells in a dose-dependent fashion." | 3.69 | Thyroid hormones enhance hypoxia-induced erythropoietin production in vitro. ( Fandrey, J; Frede, S; Jelkmann, W; Pagel, H; Wolff, M, 1994) |
"Circulatory levels of triiodothyronine (T3) and thyroxine (T4) and their kinetics were studied in rabbits exposed to intermittent hypobaric hypoxia (5200 m, 395 mm Hg, PO2 83 mm Hg) 6 h daily for 5 weeks in a decompression chamber maintained at room temperature of 22 degrees-24 degrees C." | 3.68 | Thyroid function during intermittent exposure to hypobaric hypoxia. ( Malhotra, AS; Sawhney, RC, 1990) |
"Factors affecting halothane (H) hepatotoxicity were investigated in two animal models: 1) the phenobarbital-hypoxia model, and 2) the triiodothyronine (T3) model; in the latter we previously have shown that centrilobular necrosis occurs in T3 pretreated rats anesthetized with 1% H, in 21% oxygen for 2 h." | 3.66 | Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications. ( Phythyon, JM; Uetrecht, J; Wood, AJ; Wood, M, 1983) |
"Tissue hypoxia is one of the main pathophysiologic mechanisms in sepsis and particularly in COVID-19." | 2.82 | The Potential of Thyroid Hormone Therapy in Severe COVID-19: Rationale and Preliminary Evidence. ( Alexandrou, N; Apostolaki, V; Avdikou, M; Giannoulopoulou, M; Kokkinos, L; Mourouzis, I; Pantos, C; Trikas, A; Tseti, I; Vassi, A, 2022) |
" Montmorillonite at dosage of 1." | 1.33 | Montmorillonite ameliorates hyperthyroidism of rats and mice attributed to its adsorptive effect. ( Cai, Y; Cao, YX; Lu, H; Meng, XF; Zhou, LZ; Zhu, SF, 2006) |
"Alveolar hypoventilation is known to occur in myxedema." | 1.25 | Ventilatory control in myxedema and hypothyroidism. ( Hofeldt, FD; Lufkin, EG; Pierson, DJ; Weil, JV; Zwillich, CW, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 22 (44.00) | 18.7374 |
1990's | 8 (16.00) | 18.2507 |
2000's | 13 (26.00) | 29.6817 |
2010's | 3 (6.00) | 24.3611 |
2020's | 4 (8.00) | 2.80 |
Authors | Studies |
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Mourouzis, I | 1 |
Apostolaki, V | 1 |
Trikas, A | 1 |
Kokkinos, L | 1 |
Alexandrou, N | 1 |
Avdikou, M | 1 |
Giannoulopoulou, M | 1 |
Vassi, A | 1 |
Tseti, I | 1 |
Pantos, C | 1 |
Varghese, T | 1 |
Rejish Kumar, VJ | 1 |
Anand, G | 1 |
Dasgupta, S | 1 |
Pal, AK | 1 |
Tani, N | 1 |
Ishikawa, M | 1 |
Watanabe, M | 1 |
Ikeda, T | 1 |
Ishikawa, T | 1 |
Xie, YL | 1 |
Mei, S | 1 |
Xiong, YL | 1 |
Liu, SY | 1 |
Xu, CL | 1 |
Avivi, A | 1 |
Nevo, E | 1 |
Cohen, K | 1 |
Sotnichenko, N | 1 |
Hercbergs, A | 1 |
Band, M | 1 |
Davis, PJ | 1 |
Ellis, M | 1 |
Ashur-Fabian, O | 1 |
Richalet, JP | 1 |
Letournel, M | 1 |
Souberbielle, JC | 1 |
Hou, TD | 2 |
Du, JZ | 2 |
Druyan, S | 1 |
Levi, E | 1 |
Shinder, D | 1 |
Stern, T | 1 |
González-Cinca, N | 2 |
Rivera, F | 1 |
Carreras, J | 2 |
Climent, F | 2 |
GURNEY, CW | 1 |
FRIED, W | 1 |
FOYE, LV | 1 |
GEORGI, P | 1 |
KLIMPEL, L | 1 |
NOWAK, W | 1 |
HELM, A | 1 |
Blacker, HA | 1 |
Orgeig, S | 1 |
Daniels, CB | 1 |
Pérez de la Ossa, P | 1 |
Hassanzadeh, M | 1 |
Fard, MH | 1 |
Buyse, J | 1 |
Bruggeman, V | 1 |
Decuypere, E | 2 |
Frangioni, G | 1 |
Atzori, A | 1 |
Balzi, M | 1 |
Fuzzi, G | 1 |
Ghinassi, A | 1 |
Pescosolido, N | 1 |
Bianchi, S | 1 |
Borgioli, G | 1 |
Oltmanns, KM | 1 |
Gehring, H | 1 |
Rudolf, S | 1 |
Schultes, B | 1 |
Schweiger, U | 1 |
Born, J | 1 |
Fehm, HL | 1 |
Peters, A | 1 |
Imoberdorf, R | 1 |
Garlick, PJ | 1 |
McNurlan, MA | 1 |
Casella, GA | 1 |
Marini, JC | 1 |
Turgay, M | 1 |
Bärtsch, P | 1 |
Ballmer, PE | 1 |
Cai, Y | 1 |
Meng, XF | 1 |
Cao, YX | 1 |
Lu, H | 1 |
Zhu, SF | 1 |
Zhou, LZ | 1 |
Benso, A | 1 |
Broglio, F | 1 |
Aimaretti, G | 1 |
Lucatello, B | 1 |
Lanfranco, F | 1 |
Ghigo, E | 1 |
Grottoli, S | 1 |
Simonides, WS | 1 |
Mulcahey, MA | 1 |
Redout, EM | 1 |
Muller, A | 1 |
Zuidwijk, MJ | 1 |
Visser, TJ | 1 |
Wassen, FW | 1 |
Crescenzi, A | 1 |
da-Silva, WS | 1 |
Harney, J | 1 |
Engel, FB | 1 |
Obregon, MJ | 1 |
Larsen, PR | 1 |
Bianco, AC | 1 |
Huang, SA | 1 |
Bazhenov, IuI | 1 |
Sydykov, BK | 1 |
Camba, E | 1 |
Montestruque, S | 1 |
Alvarez, J | 1 |
Mogutov, SS | 1 |
Zaĭchik, AM | 1 |
Sergeeva, ES | 1 |
Uetrecht, J | 1 |
Wood, AJ | 1 |
Phythyon, JM | 1 |
Wood, M | 1 |
Vasta, M | 1 |
Donati, L | 1 |
Varela, V | 1 |
Houssay, AB | 1 |
Lopardo, MI | 1 |
Caro, J | 1 |
Silver, R | 1 |
Erslev, AJ | 1 |
Miller, OP | 1 |
Birgegard, G | 1 |
Moshang, T | 1 |
Chance, KH | 1 |
Kaplan, MM | 1 |
Utiger, RD | 1 |
Takahashi, O | 1 |
Fandrey, J | 1 |
Pagel, H | 1 |
Frede, S | 1 |
Wolff, M | 1 |
Jelkmann, W | 1 |
Gunga, HC | 1 |
Kirsch, K | 1 |
Röcker, L | 1 |
Schobersberger, W | 1 |
Dewil, E | 1 |
Buys, N | 1 |
Albers, GA | 1 |
Pissarek, M | 1 |
Bigard, X | 1 |
Mateo, P | 1 |
Guezennec, CY | 1 |
Hoerter, JA | 1 |
Mart'ianov, AA | 1 |
Emel'ianova, TG | 1 |
Obukhova, MF | 1 |
Volkova, NV | 1 |
Riabinina, MA | 1 |
Vakulina, OP | 1 |
Sakharov, IIu | 1 |
Ashmarin, IP | 1 |
Symonds, ME | 1 |
Andrews, DC | 1 |
Johnson, P | 1 |
Ervin, MG | 1 |
Padbury, JF | 1 |
Polk, DH | 1 |
Ikegami, M | 1 |
Berry, LM | 1 |
Jobe, AH | 1 |
Wright, AD | 1 |
Kwarecki, K | 1 |
Debiec, H | 1 |
Wróblewski, S | 1 |
Woeber, KA | 2 |
Zwillich, CW | 1 |
Pierson, DJ | 1 |
Hofeldt, FD | 1 |
Lufkin, EG | 1 |
Weil, JV | 1 |
Snyder, GK | 1 |
Farrelly, C | 1 |
Coelho, JR | 1 |
Sawhney, RC | 1 |
Malhotra, AS | 1 |
Gelman, S | 1 |
Peschle, C | 1 |
Sasso, GF | 1 |
Mastroberardino, G | 1 |
Condorelli, M | 1 |
Ingbar, SH | 1 |
Sondack, DL | 1 |
Fletcher, JW | 2 |
Gallagher, NI | 2 |
Warnecke, MA | 2 |
Donati, RM | 2 |
Surks, MI | 1 |
2 reviews available for triiodothyronine and Hypoxia
Article | Year |
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The Potential of Thyroid Hormone Therapy in Severe COVID-19: Rationale and Preliminary Evidence.
Topics: COVID-19 Drug Treatment; Humans; Hypoxia; Sepsis; Thyroid Hormones; Triiodothyronine | 2022 |
THE MODIFICATION OF RADIOSENSITIVITY.
Topics: Alkylating Agents; Dactinomycin; Hypothermia; Hypoxia; Pharmacology; Pyrimidines; Radiation Effects; | 1963 |
48 other studies available for triiodothyronine and Hypoxia
Article | Year |
---|---|
Dietary GABA enhances hypoxia tolerance of a bottom-dwelling carp, Cirrhinus mrigala by modulating HIF-1α, thyroid hormones and metabolic responses.
Topics: Adaptation, Physiological; Animals; Carps; Cyprinidae; Diet; gamma-Aminobutyric Acid; Hypoxia; Hypox | 2020 |
Thyroid-related hormones as potential markers of hypoxia/ischemia.
Topics: Adult; Aged; Aged, 80 and over; Asphyxia; Autopsy; Biomarkers; Female; Head Injuries, Closed; Humans | 2020 |
[Effects of simulated 5 500 m hypobaric and hypoxia on HPT axis and intestinal flora in rats].
Topics: Animals; Gastrointestinal Microbiome; Hypoxia; Male; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyr | 2020 |
They live in the land down under: thyroid function and basal metabolic rate in the Blind Mole Rat, Spalax.
Topics: Animals; Basal Metabolism; Environment; Female; Hematocrit; Hemoglobins; Humidity; Hypoxia; Israel; | 2014 |
Effects of high-altitude hypoxia on the hormonal response to hypothalamic factors.
Topics: Adult; Altitude; Altitude Sickness; Analysis of Variance; Follicle Stimulating Hormone; Gonadotropin | 2010 |
[Changes in serum T3, T4 and TRH contents of hypothalamus induced by hypoxia in rats].
Topics: Altitude; Animals; Hypothalamus; Hypoxia; Male; Rats; Rats, Wistar; Thyrotropin-Releasing Hormone; T | 2001 |
Reduced O2 concentration during CAM development--its effect on physiological parameters of broiler embryos.
Topics: Animals; Blood Chemical Analysis; Body Temperature; Chick Embryo; Chickens; Chorioallantoic Membrane | 2012 |
Effects of hypoxia and thyroid hormone on mRNA levels and activity of phosphoglycerate mutase in rabbit tissues.
Topics: Animals; Brain; Hypoxia; Isoenzymes; Liver; Male; Muscle, Skeletal; Phosphoglycerate Mutase; Rabbits | 2003 |
FURTHER STUDIES ON THE ERYTHROPOIETIC EFFECT OF ANDROGENS.
Topics: Androgens; Animals; Basal Metabolism; Drug Synergism; Epoetin Alfa; Erythropoiesis; Erythropoietin; | 1965 |
[THE EFFECTS OF HYPOXIA AND HYPOTHERMIA IN ANESTHETIZED RABBITS ON THE TRIIODOTHYRONINE-ERYTHROCYTE UPTAKE TEST].
Topics: Animals; Electrocardiography; Erythrocytes; Hypothermia; Hypothermia, Induced; Hypoxia; Metabolism; | 1964 |
Hypoxic control of the development of the surfactant system in the chicken: evidence for physiological heterokairy.
Topics: Animals; Chick Embryo; Chickens; Corticosterone; Dexamethasone; Glucocorticoids; Hypoxia; Lipid Meta | 2004 |
Effects of thyroid hormone and hypoxia on 2,3-bisphosphoglycerate, bisphosphoglycerate synthase and phosphoglycerate mutase in rabbit erythroblasts and reticulocytes in vivo.
Topics: 2,3-Diphosphoglycerate; Animals; Bisphosphoglycerate Mutase; Erythroblasts; Hyperthyroidism; Hypoxia | 2004 |
Norepinephrine attenuates hypoxia-inhibited thyrotropin-releasing hormone release in median eminence and paraventricular nucleus of rat hypothalamus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atmosphere Exposure Chambers; Atmo | 2005 |
Effect of chronic hypoxia during embryonic development on physiological functioning and on hatching and post-hatching parameters related to ascites syndrome in broiler chickens.
Topics: Altitude; Animals; Ascites; Chick Embryo; Chickens; Corticosterone; Hypoxia; Lactic Acid; Ovum; Poul | 2004 |
Thyroid and hypoxic stress in the newt Triturus carnifex.
Topics: Animals; Fatty Liver; Female; Heart Rate; Histocytochemistry; Hypoxia; Kidney; Male; Melanosis; Pitu | 2006 |
Persistent suppression of resting energy expenditure after acute hypoxia.
Topics: Adult; Blood Glucose; Cross-Over Studies; Double-Blind Method; Energy Metabolism; Epinephrine; Gluco | 2006 |
Skeletal muscle protein synthesis after active or passive ascent to high altitude.
Topics: Adult; Alkalosis; Altitude; Deuterium; Environmental Exposure; Female; Follow-Up Studies; Humans; Hy | 2006 |
Montmorillonite ameliorates hyperthyroidism of rats and mice attributed to its adsorptive effect.
Topics: Adsorption; Animals; Antithyroid Agents; Bentonite; Disease Models, Animal; Dose-Response Relationsh | 2006 |
Endocrine and metabolic responses to extreme altitude and physical exercise in climbers.
Topics: Adult; Altitude; Body Weight; Estradiol; Exercise; Human Growth Hormone; Humans; Hypoxia; Insulin-Li | 2007 |
Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats.
Topics: Animals; Enzyme Induction; Hypertrophy, Right Ventricular; Hypoxia; Hypoxia-Inducible Factor 1, alph | 2008 |
[Role of thyroid gland hormones in thermoregulatory reactions during adaptation to high altitude].
Topics: Adaptation, Physiological; Altitude; Animals; Antithyroid Agents; Body Temperature Regulation; Hypox | 1981 |
Hypoxia and cold: influence on cellular oxygen consuming systems in guinea pig liver.
Topics: Altitude; Animals; Catalase; Cold Temperature; Electron Transport Complex IV; Guinea Pigs; Hypoxia; | 1980 |
[Effect of a hypoxic-hypercapnic gaseous medium and lowered temperature on the functional state of the rat hypothalamo-hypophyseal-thyroid system].
Topics: Animals; Cold Temperature; Hypercapnia; Hypothalamo-Hypophyseal System; Hypoxia; Male; Rats; Thyroid | 1984 |
Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications.
Topics: Animals; Chemical and Drug Induced Liver Injury; Fasting; Fluorides; Halothane; Hypoxia; Liver Disea | 1983 |
[Relation between hypoxia and thyroid function].
Topics: Altitude; Animals; Graves Disease; Humans; Hypoxia; Oxygen Consumption; Rats; Space Flight; Thyroid | 1982 |
Modifications of the pituitary-thyroid axis induced by hypobaric hypoxia.
Topics: Animals; Hypoxia; Male; Pituitary Gland; Pressure; Radioimmunoassay; Rats; Thyroid Gland; Thyrotropi | 1982 |
Erythropoietin production in fasted rats. Effects of thyroid hormones and glucose supplementation.
Topics: Acid-Base Equilibrium; Animals; Biological Assay; Dietary Carbohydrates; Erythropoietin; Fasting; Gl | 1981 |
Effects of hypoxia on thyroid function tests.
Topics: Adolescent; Child; Child, Preschool; Humans; Hypoxia; Infant; Thyroid Function Tests; Thyroid Gland; | 1980 |
Thyroid hormones enhance hypoxia-induced erythropoietin production in vitro.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Cells, Cultured; DNA; Dose-Response Relation | 1994 |
Time course of erythropoietin, triiodothyronine, thyroxine, and thyroid-stimulating hormone at 2,315 m.
Topics: Adult; Altitude; Blood Cell Count; Erythropoietin; Hemoglobins; Humans; Hypoxia; Male; Middle Aged; | 1994 |
Different characteristics in chick embryos of two broiler lines differing in susceptibility to ascites.
Topics: Animals; Ascites; Carbon Dioxide; Chick Embryo; Chickens; Disease Susceptibility; Eggs; Hypoxia; Inc | 1996 |
Adaptation of cardiac myosin and creatine kinase to chronic hypoxia: role of anorexia and hypertension.
Topics: Acclimatization; Adenylate Kinase; Altitude; Analysis of Variance; Animals; Anorexia; Chronic Diseas | 1997 |
[Physiologic effects of active immunization with triiodothyronine in rats].
Topics: Animals; Antibody Formation; Behavior, Animal; Body Temperature; Body Weight; Hyperthyroidism; Hypox | 1998 |
The influence of acute hypoxia and carotid body denervation on thermoregulation during non-rapid eye movement sleep in the developing lamb.
Topics: Animals; Animals, Newborn; Autonomic Denervation; Blood Glucose; Body Temperature; Body Temperature | 1999 |
Antenatal glucocorticoids alter premature newborn lamb neuroendocrine and endocrine responses to hypoxia.
Topics: Angiotensin II; Animals; Animals, Newborn; Arginine Vasopressin; Atrial Natriuretic Factor; Betameth | 2000 |
Birmingham Medical Research Expeditionary Society 1977 Expediton: thyroid function and acute mountain sickenss.
Topics: Adult; Altitude Sickness; Expeditions; Humans; Hypoxia; Male; Middle Aged; Nepal; Thyroid Gland; Thy | 1979 |
Diurnal rhythm of secretory activity of certain endocrine glands in rats exposed to high-altitude hypoxia.
Topics: Adrenal Cortex; Altitude Sickness; Animals; Blood Glucose; Circadian Rhythm; Corticosterone; Hypoxia | 1979 |
L-triiodothyronine and L-reverse-triiodothyronine generation in the human polymorphonuclear leukocyte.
Topics: Adult; Dithiothreitol; Fetal Blood; Humans; Hypoxia; In Vitro Techniques; Infant, Newborn; Kinetics; | 1978 |
Ventilatory control in myxedema and hypothyroidism.
Topics: Adult; Humans; Hypercapnia; Hypothyroidism; Hypoventilation; Hypoxia; Lung; Middle Aged; Myxedema; R | 1975 |
Adaptations in skeletal muscle capillarity following changes in oxygen supply and changes in oxygen demands.
Topics: Adaptation, Physiological; Animals; Capillary Action; Cold Temperature; Fluorescent Dyes; Hypoxia; M | 1992 |
Thyroid function during intermittent exposure to hypobaric hypoxia.
Topics: Animals; Atmospheric Pressure; Hypoxia; Male; Rabbits; Thyroid Gland; Thyroxine; Triiodothyronine | 1990 |
Halothane hepatotoxicity--again?
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Guinea Pigs; Halothane; Humans; | 1986 |
The mechanism of endocrine influences on erythropoiesis.
Topics: Adrenocorticotropic Hormone; Animals; Drug Synergism; Erythropoiesis; Erythropoietin; Female; Hydroc | 1971 |
Metabolism of L-thyroxine by phagocytosing human leukocytes.
Topics: Calcium; Chromatography, Paper; Colchicine; Humans; Hydrogen Peroxide; Hypoxia; In Vitro Techniques; | 1973 |
Spectrophotometric determination of thyroxine iodine in thyroid preparations.
Topics: Animals; Goiter; Hypoxia; Iodine; Mathematics; Mice; Rats; Spectrophotometry, Ultraviolet; Tablets; | 1973 |
Erythropoiesis and hyperoxia.
Topics: Animals; Biological Assay; Environment, Controlled; Erythrocytes; Erythropoiesis; Erythropoietin; Fe | 1973 |
Erythropoiesis in hypothyroidism.
Topics: Animals; Biological Assay; Digestive System; Erythrocytes; Erythropoiesis; Erythropoietin; Female; H | 1973 |
Effect of hypoxia on in vitro incorporation of leucine-14C into rat liver protein.
Topics: Animals; Carbon Isotopes; Fasting; Hypoxia; In Vitro Techniques; Leucine; Male; Microsomes, Liver; P | 1970 |