Compounds > triiodothyronine
Page last updated: 2024-11-08

triiodothyronine and Hypothermia

triiodothyronine has been researched along with Hypothermia in 40 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
"Hypothermia and tremor responses of oxotremorine and eserine were studied in rats after several T3 treatment regimens."7.68Triiodothyronine (T3) modifies cholinergic-induced hypothermia and tremor in rats. ( Almeida, OM; Santos, R, 1993)
"Myxoedema coma is fortunately rare and is probably rarer in a warm climate such as Australia."5.26A case of myxoedema coma successfully treated by low dose oral triiodothyronine. ( Graham, JJ; Harding, PE, 1977)
"Hypothermia and tremor responses of oxotremorine and eserine were studied in rats after several T3 treatment regimens."3.68Triiodothyronine (T3) modifies cholinergic-induced hypothermia and tremor in rats. ( Almeida, OM; Santos, R, 1993)
"Eight cases of hypothyroid coma observed between 1971 and 1981 are reported, and their main clinical, biological and therapeutic features described."1.27[Myxedema coma. Apropos of 8 cases]. ( Charbonnel, B; de Rostu, H; Desjars, P, 1983)
"Myxoedema coma is fortunately rare and is probably rarer in a warm climate such as Australia."1.26A case of myxoedema coma successfully treated by low dose oral triiodothyronine. ( Graham, JJ; Harding, PE, 1977)
"A 71-year-old woman with myxoedema coma presenting in status epilepticus is reported."1.26Myxoedema coma presenting in status epilepticus. ( Holmes, GK; Woods, KL, 1977)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199030 (75.00)18.7374
1990's6 (15.00)18.2507
2000's2 (5.00)29.6817
2010's2 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spyridoulias, A1
Riaz, MS1
Moriyama, T1
Tsuneyoshi, I1
Omae, T1
Takeyama, M1
Kanmura, Y1
Lifschytz, T1
Zozulinsky, P1
Eitan, R1
Landshut, G1
Ohayon, S1
Lerer, B1
BRUNE, DF2
der KINDEREN, PJ2
SCHWARZ, F2
VARMA, DR1
GILLIS, RA1
MELVILLE, KI1
VERBOV, JL1
GALE, CC1
NIELSEN, PE1
RANLOV, P1
BELLAU, AR1
BACON, AP1
GENT, AE1
GRINO, E1
FIANDRA, O1
APPELTAUER, LC1
VINCENT, O1
GROSSO, O1
CERVINO, JM1
FOYE, LV1
LETTAU, HF1
SELLERS, EA1
SCHOENBAUM, E1
GEORGI, P1
KLIMPEL, L1
NOWAK, W1
HELM, A1
Cabello, G1
Desjars, P1
de Rostu, H1
Charbonnel, B1
Bacci, V1
Schussler, GC1
Kaplan, TB1
Sobolev, VI1
Merkhelevich, LG1
Makhsudov, MS1
Hissa, R1
John, MT1
Pilo, B1
Viswanathan, M1
George, JC1
Fregly, MJ1
Rossi, F1
Cade, JR1
Almeida, OM1
Santos, R1
Yang, Y1
Gordon, CJ1
Doerfler, RE1
Edens, FW1
Parkhurst, CR1
Havenstein, GB1
Qureshi, MA1
Gauthier, K1
Plateroti, M1
Harvey, CB1
Williams, GR1
Weiss, RE1
Refetoff, S1
Willott, JF1
Sundin, V1
Roux, JP1
Malaval, L1
Hara, M1
Samarut, J1
Chassande, O1
Graham, JJ1
Harding, PE1
Woods, KL1
Holmes, GK1
Frankel, RJ1
Jenkins, JS1
Heal, DJ1
Smith, SL1
Nakano, T1
Ito, H1
Inamatsu, T1
Murakami, M1
Rosin, AJ1
Farran, HE1
Luton, JP1
Breese, GR1
Cott, JM1
Cooper, BR1
Prange, AJ1
Lipton, MA1
Grice, K1
Blendis, LM1
Keir, MI1
Harvey, RF1
Yaffee, HS1
Schneider, PJ1
Newmark, SR1
Himathongkam, T1
Shane, JM1
Blum, M1
Woolf, PD1
Hollander, CS1
Mitsuma, T1
Lee, LA1
Schalch, DS1
Kocsard-Varo, G1

Reviews

3 reviews available for triiodothyronine and Hypothermia

ArticleYear
MYXOEDEMA COMA. TWO CASE REPORTS AND A REVIEW.
    Acta endocrinologica, 1964, Volume: 45

    Topics: Autoimmune Diseases; Coma; Geriatrics; Humans; Hydrocortisone; Hyponatremia; Hypothermia; Hypothermi

1964
THE MODIFICATION OF RADIOSENSITIVITY.
    Cancer progress, 1963, Volume: 92

    Topics: Alkylating Agents; Dactinomycin; Hypothermia; Hypoxia; Pharmacology; Pyrimidines; Radiation Effects;

1963
Myxedema coma.
    The American journal of the medical sciences, 1972, Volume: 264, Issue:6

    Topics: Adrenal Glands; Cachexia; Central Nervous System; Coma; Heart Diseases; Humans; Hypoglycemia; Hypona

1972

Trials

1 trial available for triiodothyronine and Hypothermia

ArticleYear
The effect of amino-acid infusion during off-pump coronary arterial bypass surgery on thermogenic and hormonal regulation.
    Journal of anesthesia, 2008, Volume: 22, Issue:4

    Topics: Aged; Amino Acids; Anesthesia, General; Blood Glucose; Blood Urea Nitrogen; Body Temperature Regulat

2008

Other Studies

36 other studies available for triiodothyronine and Hypothermia

ArticleYear
Myxoedema coma in the setting of hyperglycaemic hyperosmolar state.
    BMJ case reports, 2016, Jan-11, Volume: 2016

    Topics: Female; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Hypoglycemic Agents; Hypotension; Hypoth

2016
Effect of triiodothyronine on antidepressant screening tests in mice and on presynaptic 5-HT1A receptors: mediation by thyroid hormone α receptors.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 337, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amiodarone; Animals; Antidepressive Agents; Body Weight; Dos

2011
Myxoedematous coma with extreme hypothermia in a patient treated with a thyroid preparation of a very low biological activity.
    Acta endocrinologica, 1962, Volume: 41

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents, Hormonal; Ascomycota; Body Temperature; Coma; Humans

1962
On the relationship of catecholamines and thyroid activity to ventricular fibrillation during hypothermia in dogs.
    Canadian journal of biochemistry and physiology, 1963, Volume: 41

    Topics: Animals; Antithyroid Agents; Catecholamines; Dogs; Epinephrine; Hypothermia; Hypothermia, Induced; I

1963
MODERN TREATMENT OF MYXOEDEMA COMA ASSOCIATED WITH HYPOTHERMIA.
    Lancet (London, England), 1964, Jan-25, Volume: 1, Issue:7326

    Topics: Coma; Geriatrics; Humans; Hydrocortisone; Hypothermia; Myxedema; Thyroxine; Triiodothyronine

1964
NON-ESSENTIAL ROLE OF PROLACTIN IN THE HORMONAL RESTORATION OF LACTATION IN GOATS WITH RADIO FREQUENCY HYPOTHALAMIC LESIONS.
    Acta physiologica Scandinavica, 1963, Volume: 59

    Topics: Adrenocorticotropic Hormone; Animals; Diabetes Insipidus; Female; Goats; Growth Hormone; Humans; Hyp

1963
[MYXEDEMATOUS COMA WITH VERY LOW TEMPERATURE BROUGHT ON BY A BIOLOGICALLY INACTIVE THYROID PREPARATION].
    Nederlands tijdschrift voor geneeskunde, 1963, Nov-02, Volume: 107

    Topics: Cold Temperature; Coma; Electrocardiography; Hydrocortisone; Hypothermia; Myxedema; Temperature; Thy

1963
THE BLOOD PRESSURE IN MYXOEDEMA COMA.
    The British journal of clinical practice, 1964, Volume: 18

    Topics: Adrenocorticotropic Hormone; Blood Pressure; Blood Pressure Determination; Body Temperature; Cholest

1964
RECOVERY FROM HYPOTHERMIC MYXOEDEMA COMA.
    The Practitioner, 1964, Volume: 193

    Topics: Coma; Cortisone; Geriatrics; Humans; Hydrocortisone; Hypothermia; Myxedema; Penicillins; Triiodothyr

1964
[MYXEDEMATOUS COMA. RELATION OF A CASE WITH COMMENTS ON ITS PHYSIOPATHOLOGY AND PATHOLOGIC ANATOMY].
    Revista argentina de endocrinologia y metabolismo, 1964, Volume: 10

    Topics: Adrenal Cortex Hormones; Bronchopneumonia; Coma; Drug Therapy; Hot Temperature; Humans; Hypothermia;

1964
MODIFICATION OF DRUG-INDUCED HYPOTHERMIA.
    Canadian journal of physiology and pharmacology, 1964, Volume: 42

    Topics: Adrenocorticotropic Hormone; Body Temperature Regulation; Chlorpromazine; Hydrocortisone; Hypothermi

1964
[THE EFFECTS OF HYPOXIA AND HYPOTHERMIA IN ANESTHETIZED RABBITS ON THE TRIIODOTHYRONINE-ERYTHROCYTE UPTAKE TEST].
    Acta biologica et medica Germanica, 1964, Volume: 13

    Topics: Animals; Electrocardiography; Erythrocytes; Hypothermia; Hypothermia, Induced; Hypoxia; Metabolism;

1964
Endocrine reactivity (T3, T4, cortisol) during cold exposure in preterm and full-term lambs.
    Biology of the neonate, 1983, Volume: 44, Issue:4

    Topics: Animals; Animals, Newborn; Body Temperature; Cold Temperature; Gestational Age; Hydrocortisone; Hypo

1983
[Myxedema coma. Apropos of 8 cases].
    La Revue de medecine interne, 1983, Volume: 4, Issue:3

    Topics: Aged; Coma; Female; Hemodynamics; Humans; Hyponatremia; Hypothermia; Male; Middle Aged; Myxedema; Re

1983
The relationship between serum triiodothyronine and thyrotropin during systemic illness.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:6

    Topics: Acute Disease; Adult; Aged; Female; Humans; Hypothermia; Male; Middle Aged; Prognosis; Thyrotropin;

1982
[The effect of experimental hyper- and athyroidism on the temperature dependence of some physiological reactions].
    Fiziologicheskii zhurnal imeni I.M. Sechenova, 1995, Volume: 81, Issue:2

    Topics: Animals; Body Temperature; Body Temperature Regulation; Cold Temperature; Electrocardiography; Heart

1995
Noradrenaline-induced hypothermia is suppressed in the vagotomized cold-exposed pigeon.
    Comparative biochemistry and physiology. Part A, Physiology, 1995, Volume: 111, Issue:1

    Topics: Acetylcholine; Adrenal Glands; Animals; Basal Metabolism; Body Temperature; Cold Temperature; Columb

1995
A role for thyroid hormones in cold-induced elevation of blood pressure and cardiac hypertrophy.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:9

    Topics: Amitrole; Animals; Blood Pressure; Cardiomegaly; Catecholamines; Cold Temperature; Hypertension; Hyp

1994
Triiodothyronine (T3) modifies cholinergic-induced hypothermia and tremor in rats.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:3

    Topics: Acetylcholinesterase; Animals; Brain; Hyperthyroidism; Hypothermia; Male; Oxotremorine; Parasympatho

1993
Regulated hypothermia in the hypothyroid rat induced by administration of propylthiouracil.
    The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 2

    Topics: Animals; Behavior, Animal; Body Temperature; Body Temperature Regulation; Heat Stress Disorders; Hyp

1997
Hypothermia, hypoglycemia, and hypothyrosis associated with poult enteritis and mortality syndrome.
    Poultry science, 1998, Volume: 77, Issue:8

    Topics: Animals; Blood Glucose; Body Temperature; Enteritis; Female; Hypoglycemia; Hypothermia; Hypothyroidi

1998
Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus.
    Molecular and cellular biology, 2001, Volume: 21, Issue:14

    Topics: Animals; Bone Development; Cysteine Endopeptidases; Deafness; Down-Regulation; Embryonic and Fetal D

2001
A case of myxoedema coma successfully treated by low dose oral triiodothyronine.
    Australian and New Zealand journal of medicine, 1977, Volume: 7, Issue:2

    Topics: Aged; Coma; Humans; Hyponatremia; Hypothermia; Male; Myxedema; Respiratory Insufficiency; Thyroxine;

1977
Myxoedema coma presenting in status epilepticus.
    Postgraduate medical journal, 1977, Volume: 53, Issue:615

    Topics: Aged; Body Temperature; Coma; Female; Humans; Hypothermia; Hypothyroidism; Myxedema; Status Epilepti

1977
Hypothalamic-pituitary function in anorexia nervosa.
    Acta endocrinologica, 1975, Volume: 78, Issue:2

    Topics: Adolescent; Adult; Anorexia Nervosa; Blood Glucose; Female; Fever; Follicle Stimulating Hormone; Gon

1975
The effects of acute and repeated administration of T3 to mice on 5-HT1 and 5-HT2 function in the brain and its influence on the actions of repeated electroconvulsive shock.
    Neuropharmacology, 1988, Volume: 27, Issue:12

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Electroshock; Hypothermia; Indoles; Male; Mi

1988
[Hypothermia in the Japanese elderly].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1985, Volume: 22, Issue:3

    Topics: Aged; Humans; Hypothermia; Japan; Middle Aged; Triiodothyronine

1985
Factors influencing in vitro tests of thyroid function in the elderly.
    Journal of the American Geriatrics Society, 1968, Volume: 16, Issue:9

    Topics: Aged; Carbon Dioxide; Erythrocytes; Humans; Hydrogen-Ion Concentration; Hypothermia; In Vitro Techni

1968
[Unchecked thyroid insufficiencies].
    La Presse medicale, 1969, Jun-25, Volume: 77, Issue:31

    Topics: Aged; Anuria; Coma; Cortisone; Female; Heating; Hemorrhage; Humans; Hypoglycemia; Hypopituitarism; H

1969
Antagonism of ethanol narcosis by thyrotropin releasing hormone.
    Life sciences, 1974, Mar-16, Volume: 14, Issue:6

    Topics: Amides; Amphetamine; Animals; Cisterna Magna; Ethanol; Glutamates; Histidine; Hypothermia; Male; Mic

1974
Accidental hypothermia in erythroderma from generalized psoriasis.
    Archives of dermatology, 1968, Volume: 98, Issue:3

    Topics: Aged; Arthritis; Dermatitis, Exfoliative; Electrocardiography; Female; Humans; Hypothermia; Pneumoni

1968
Hypothermic coma and exfoliative dermatitis.
    JAMA, 1969, Jan-13, Volume: 207, Issue:2

    Topics: Aged; Coma; Dermatitis, Exfoliative; Female; Humans; Hydrocortisone; Hypothermia; Triiodothyronine

1969
Respiratory depression in the coma of myxedema: treatment with ethamivan intravenously.
    Journal of the American Geriatrics Society, 1969, Volume: 17, Issue:10

    Topics: Aged; Benzamides; Benzoates; Central Nervous System Stimulants; Coma; Electrocardiography; Humans; H

1969
Myxedema coma.
    JAMA, 1974, Nov-11, Volume: 230, Issue:6

    Topics: Administration, Oral; Adrenal Cortex Hormones; Age Factors; Aged; Coma; Emergencies; Humans; Hyponat

1974
Accidental hypothermia: endocrine function during recovery.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:3

    Topics: Adult; Aged; Antigens; Blood Glucose; Body Temperature; Female; Growth Hormone; Humans; Hydrocortiso

1972
Letter: Sudden infant death syndrome and triiodothyronine (T3) serum levels.
    The Medical journal of Australia, 1973, Oct-20, Volume: 2, Issue:16

    Topics: Body Temperature Regulation; Death, Sudden; Humans; Hypothermia; Infant; Infant, Newborn; Triiodothy

1973