triiodothyronine has been researched along with Hyperphagia in 21 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Hyperphagia: Ingestion of a greater than optimal quantity of food.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To investigate the hyperphagic response to triiodothyronine (T(3))-induced thyrotoxicosis, adult male rats were studied 7 days after daily intraperitoneal injections of T(3) or vehicle." | 7.72 | Hypothalamic neuropeptide Y/Y1 receptor pathway activated by a reduction in circulating leptin, but not by an increase in circulating ghrelin, contributes to hyperphagia associated with triiodothyronine-induced thyrotoxicosis. ( Ishii, S; Kamegai, J; Oikawa, S; Shimizu, T; Sugihara, H; Tamura, H, 2003) |
| " Here we demonstrate that either whole-body hyperthyroidism or central administration of triiodothyronine (T3) decreases the activity of hypothalamic AMP-activated protein kinase (AMPK), increases sympathetic nervous system (SNS) activity and upregulates thermogenic markers in brown adipose tissue (BAT)." | 3.76 | Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance. ( Agassandian, K; Carling, D; Chatterjee, K; Diéguez, C; Gallego, R; González, CR; Lage, R; Lelliott, C; López, M; Martínez de Morentin, PB; Morgan, DA; Nogueiras, R; Oresic, M; Rahmouni, K; Rodríguez-Cuenca, S; Saha, AK; Schoenmakers, E; Tovar, S; Varela, L; Vázquez, MJ; Velagapudi, VR; Vidal-Puig, A, 2010) |
| " Rats raised in a small litter can develop hyperinsulinaemia, hyperphagia, hyperleptinaemia and hypertension as adults." | 3.75 | Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats. ( de Moura, EG; Dutra, SC; Lisboa, PC; Passos, MC; Rodrigues, AL, 2009) |
| " To investigate the hyperphagic response to triiodothyronine (T(3))-induced thyrotoxicosis, adult male rats were studied 7 days after daily intraperitoneal injections of T(3) or vehicle." | 3.72 | Hypothalamic neuropeptide Y/Y1 receptor pathway activated by a reduction in circulating leptin, but not by an increase in circulating ghrelin, contributes to hyperphagia associated with triiodothyronine-induced thyrotoxicosis. ( Ishii, S; Kamegai, J; Oikawa, S; Shimizu, T; Sugihara, H; Tamura, H, 2003) |
| " In young adult rats, mixed calorie overfeeding increases triiodothyronine production and decreases weight gain efficiency compared with chow diets." | 3.68 | Increasing age impairs the thyroid hormone response to overfeeding. ( Katzeff, HL, 1990) |
| " These data indicate that many patients with bulimia showed the metabolic signs of starvation at the time of the study, a finding supported by the symptoms of endocrine adaptation to starvation, namely low triiodothyronine and a decreased noradrenaline response to an orthostatic test in many of these patients." | 3.67 | Metabolic and endocrine indices of starvation in bulimia: a comparison with anorexia nervosa. ( Pahl, J; Pirke, KM; Schweiger, U; Warnhoff, M, 1985) |
| "Resting oxygen consumption (VO2) before and after injection of noradrenaline (NA), and plasma triiodothyronine levels were elevated in hyperthyroid and hyperphagic cafeteria fed rats, but were reduced in 4d-fasted and hypothyroid animals compared to controls." | 3.66 | Catecholamine and thyroid hormone influence on brown fat Na+, K+-ATPase activity and thermogenesis in the rat. ( Rothwell, NJ; Saville, ME; Stock, MJ; Wyllie, MG, 1982) |
| "Hyperthyroidism is known to increase food intake and central administration of thyroid hormone shows acute orexigenic effects in rodents." | 1.40 | Thyroid hormone modulates food intake and glycemia via ghrelin secretion in Zucker fatty rats. ( Dhanesha, N; Jain, MR; Joharapurkar, A; Kshirsagar, S; Patel, K; Patel, V; Raval, P; Raval, S, 2014) |
| "Hyperthyroidism is characterized in rats by increased energy expenditure and marked hyperphagia." | 1.38 | Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism. ( Chatterjee, K; Diéguez, C; Gallego, R; Gándara, M; López, M; Martínez-Sánchez, N; Nogueiras, R; Roa, J; Schoenmakers, E; Tena-Sempere, M; Varela, L; Vázquez, MJ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (42.86) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patel, K | 1 |
| Joharapurkar, A | 1 |
| Dhanesha, N | 1 |
| Patel, V | 1 |
| Kshirsagar, S | 1 |
| Raval, P | 1 |
| Raval, S | 1 |
| Jain, MR | 1 |
| Zhao, Y | 1 |
| Xue, Q | 1 |
| Su, X | 1 |
| Xie, L | 1 |
| Yan, Y | 1 |
| Steinman, AD | 1 |
| Zheng, F | 1 |
| Guo, G | 1 |
| Wang, BL | 1 |
| Liang, DC | 1 |
| Zhang, R | 1 |
| Zhang, JY | 1 |
| Zhao, XQ | 1 |
| Chen, ZP | 1 |
| Rodrigues, AL | 1 |
| de Moura, EG | 1 |
| Passos, MC | 1 |
| Dutra, SC | 1 |
| Lisboa, PC | 1 |
| Vendrell, JF | 1 |
| Hoa, D | 1 |
| Gahide, G | 1 |
| López, M | 2 |
| Varela, L | 2 |
| Vázquez, MJ | 2 |
| Rodríguez-Cuenca, S | 1 |
| González, CR | 1 |
| Velagapudi, VR | 1 |
| Morgan, DA | 1 |
| Schoenmakers, E | 2 |
| Agassandian, K | 1 |
| Lage, R | 1 |
| Martínez de Morentin, PB | 1 |
| Tovar, S | 1 |
| Nogueiras, R | 2 |
| Carling, D | 1 |
| Lelliott, C | 1 |
| Gallego, R | 2 |
| Oresic, M | 1 |
| Chatterjee, K | 2 |
| Saha, AK | 1 |
| Rahmouni, K | 1 |
| Diéguez, C | 2 |
| Vidal-Puig, A | 1 |
| Martínez-Sánchez, N | 1 |
| Roa, J | 1 |
| Gándara, M | 1 |
| Tena-Sempere, M | 1 |
| Ishii, S | 1 |
| Kamegai, J | 1 |
| Tamura, H | 1 |
| Shimizu, T | 1 |
| Sugihara, H | 1 |
| Oikawa, S | 1 |
| Rothwell, NJ | 2 |
| Saville, ME | 1 |
| Stock, MJ | 2 |
| Wyllie, MG | 1 |
| Mitchell, JE | 1 |
| Bantle, JP | 1 |
| Welle, S | 1 |
| O'Connell, M | 2 |
| Danforth, E | 2 |
| Campbell, R | 1 |
| Laessle, RG | 1 |
| Platte, P | 1 |
| Schweiger, U | 2 |
| Pirke, KM | 2 |
| Almeida, NG | 1 |
| Levitsky, DA | 1 |
| Strupp, B | 1 |
| Geracioti, TD | 1 |
| Loosen, PT | 1 |
| Gold, PW | 1 |
| Kling, MA | 1 |
| Katzeff, HL | 2 |
| Horton, ES | 1 |
| Young, JB | 1 |
| Landsberg, L | 1 |
| Abraham, G | 1 |
| Falcou, R | 1 |
| Rozen, R | 1 |
| Mandenoff, A | 1 |
| Autissier, N | 1 |
| Apfelbaum, M | 1 |
| Harris, RB | 1 |
| Kasser, TR | 1 |
| Martin, RJ | 1 |
| Pahl, J | 1 |
| Warnhoff, M | 1 |
| Naim, M | 1 |
| Brand, JG | 1 |
| Kare, MR | 1 |
| Carpenter, RG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Brown Adipose Tissue Activity and Thyroid Hormone[NCT02499471] | 12 participants (Actual) | Interventional | 2012-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 other studies available for triiodothyronine and Hyperphagia
| Article | Year |
|---|---|
Thyroid hormone modulates food intake and glycemia via ghrelin secretion in Zucker fatty rats.
Topics: Animals; Appetite Regulation; Blood Glucose; Disease Models, Animal; Eating; Feeding Behavior; Ghrel | 2014 |
Microcystin-LR induced thyroid dysfunction and metabolic disorders in mice.
Topics: Animals; Behavior, Animal; Biomarkers; Blood Glucose; Dose-Response Relationship, Drug; Eating; Endo | 2015 |
[Overdose of iodine on expression of CCK gene in rat brains].
Topics: Animals; Brain; Cholecystokinin; Drug Overdose; Female; Food, Formulated; Gene Expression; Hyperphag | 2008 |
Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats.
Topics: Age Factors; Aging; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Blotting, | 2009 |
Mature teratoma arising from the sella.
Topics: Contrast Media; Gadolinium DTPA; Humans; Hyperphagia; Infant; Magnetic Resonance Imaging; Male; Pitu | 2010 |
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance.
Topics: Adipose Tissue, Brown; Agouti-Related Protein; AMP-Activated Protein Kinases; Animals; Arcuate Nucle | 2010 |
Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism.
Topics: Agouti-Related Protein; AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Eating; Feed | 2012 |
Hypothalamic neuropeptide Y/Y1 receptor pathway activated by a reduction in circulating leptin, but not by an increase in circulating ghrelin, contributes to hyperphagia associated with triiodothyronine-induced thyrotoxicosis.
Topics: Animals; Arginine; Body Weight; Eating; Energy Metabolism; Gastric Mucosa; Gene Expression; Ghrelin; | 2003 |
Catecholamine and thyroid hormone influence on brown fat Na+, K+-ATPase activity and thermogenesis in the rat.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Fasting; Humans; Hyperphagia; Hyperthyr | 1982 |
Metabolic and endocrine investigations in women of normal weight with the bulimia syndrome.
Topics: Adult; Blood Glucose; Feeding and Eating Disorders; Female; Growth Hormone; Hormones; Humans; Hyperp | 1983 |
Decreased free fraction of serum thyroid hormones during carbohydrate overfeeding.
Topics: Adult; Dietary Carbohydrates; Humans; Hyperphagia; Male; Prealbumin; Serum Albumin; Thyroid Hormones | 1984 |
Effects of feeding a palatable "cafeteria' diet on energy balance in young and adult lean (+/?) Zucker rats.
Topics: Adipose Tissue, Brown; Age Factors; Animals; Blood Glucose; Body Weight; Diet; Energy Metabolism; Fe | 1982 |
Biological and psychological correlates of intermittent dieting behavior in young women. A model for bulimia nervosa.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Affect; Body Weight; Bulimia; Diet, Reducing; Energy Intak | 1996 |
Enhanced thermogenesis during recovery from diet-induced weight gain in the rat.
Topics: Animals; Body Composition; Body Temperature Regulation; Diet; Dietary Carbohydrates; Dietary Fats; E | 1996 |
Cortisol, thyroid hormone, and mood in atypical depression: a longitudinal case study.
Topics: Adult; Affect; Depressive Disorder; Disorders of Excessive Somnolence; Female; Fluoxetine; Humans; H | 1992 |
Increasing age impairs the thyroid hormone response to overfeeding.
Topics: Adipose Tissue, Brown; Aging; Animals; Energy Intake; Hyperphagia; Iodide Peroxidase; Liver; Male; O | 1990 |
Metabolic studies in human obesity during overnutrition and undernutrition: thermogenic and hormonal responses to norepinephrine.
Topics: Adult; Basal Metabolism; Body Composition; Body Temperature Regulation; Energy Metabolism; Feeding a | 1986 |
The effects of a constant T3 level and thermoneutrality in diet-induced hyperphagia.
Topics: Adipose Tissue; Animals; Body Weight; Diet; Energy Intake; Energy Metabolism; Feeding and Eating Dis | 1987 |
Dynamics of recovery of body composition after overfeeding, food restriction or starvation of mature female rats.
Topics: Animals; Body Composition; Body Weight; Feeding and Eating Disorders; Female; Food Deprivation; Hype | 1986 |
Metabolic and endocrine indices of starvation in bulimia: a comparison with anorexia nervosa.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Anorexia Nervosa; Fatty Acids, Nonesterified; Feeding and | 1985 |
Energy intake, weight gain and fat deposition in rats fed flavored, nutritionally controlled diets in a multichoice ("cafeteria") design.
Topics: Adipose Tissue, Brown; Analysis of Variance; Animals; Body Weight; Dietary Carbohydrates; Dietary Fa | 1985 |