triiodothyronine has been researched along with Hyperinsulinism in 14 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Overall obesity is associated with elevated serum triiodothyronine concentrations and insulin resistance." | 9.09 | Triiodothyronine: a link between the insulin resistance syndrome and blood pressure? ( Bakker, SJ; Gans, RO; Heine, RJ; Popp-Snijders, C; ter Maaten, JC, 1999) |
| "Carvedilol treatment reversed thyroxin induced hypertriglyceridemia, whereas propranolol treatment had no effect." | 5.34 | Comparative effectiveness of carvedilol and propranolol on glycemic control and insulin resistance associated with L-thyroxin-induced hyperthyroidism--an experimental study. ( Bhatt, P; Goyal, R; Makwana, D; Santani, D, 2007) |
| "Overall obesity is associated with elevated serum triiodothyronine concentrations and insulin resistance." | 5.09 | Triiodothyronine: a link between the insulin resistance syndrome and blood pressure? ( Bakker, SJ; Gans, RO; Heine, RJ; Popp-Snijders, C; ter Maaten, JC, 1999) |
| " Hypothyroidism in fetal sheep induced by removal of the thyroid gland caused asymmetric organ growth, increased pancreatic beta cell mass and proliferation, and was associated with increased circulating concentrations of insulin and leptin." | 3.85 | Hypothyroidism in utero stimulates pancreatic beta cell proliferation and hyperinsulinaemia in the ovine fetus during late gestation. ( Anderson, M; Blache, D; Davenport, HM; Davis, MA; De Blasio, MJ; Forhead, AJ; Fowden, AL; Harris, SE; Kelly, AC; Limesand, SW; Meredith, D; Wooding, FBP, 2017) |
| " The fetal growth retardation, hyperleptinemia, hyperinsulinism, and cytokines distortions (transforming growth factor-beta; TGF-β, tumor necrosis factor-alpha; TNF-α, and interferon-γ; IFN-γ) were noticed at examined EDs if compared to the control group." | 3.83 | Gestational dexamethasone alters fetal neuroendocrine axis. ( Ahmed, RG, 2016) |
| "This study aimed to investigate if hyperinsulinemia and/or insulin resistance was correlated with the occurrence of papillary thyroid cancer (PTC) in a group of Chinese patients." | 1.51 | Hyperinsulinemia and thyroid peroxidase antibody in Chinese patients with papillary thyroid cancer. ( Chen, X; Guo, X; Zhang, C; Zhang, J, 2019) |
| "Moreover, hyperinsulinemia reduces the circulating level of serum T4 and conversion of T4 to T3, mimicking hypothyroidism, because thyroid hormones are necessary for the maturation of chondrocytes." | 1.46 | Serum insulin in pathogenesis and treatment of osteoarthritis. ( Askari, A; Bahramali, E; Ehrampoush, E; Farjam, M; Homayounfar, R, 2017) |
| "Carvedilol treatment reversed thyroxin induced hypertriglyceridemia, whereas propranolol treatment had no effect." | 1.34 | Comparative effectiveness of carvedilol and propranolol on glycemic control and insulin resistance associated with L-thyroxin-induced hyperthyroidism--an experimental study. ( Bhatt, P; Goyal, R; Makwana, D; Santani, D, 2007) |
| "Hyperthyroidism is characterized by increased levels of circulating free fatty acids (FFA) and increased lipid oxidation, but it is uncertain which regional fat depots contribute." | 1.31 | Elevated regional lipolysis in hyperthyroidism. ( Djurhuus, CB; Gravholt, CH; Jørgensen, JO; Møller, N; Nørrelund, H; Riis, AL; Weeke, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, X | 1 |
| Chen, X | 1 |
| Zhang, C | 2 |
| Zhang, J | 1 |
| Ahmed, RG | 1 |
| Askari, A | 1 |
| Ehrampoush, E | 1 |
| Homayounfar, R | 1 |
| Bahramali, E | 1 |
| Farjam, M | 1 |
| Harris, SE | 1 |
| De Blasio, MJ | 1 |
| Davis, MA | 1 |
| Kelly, AC | 1 |
| Davenport, HM | 1 |
| Wooding, FBP | 1 |
| Blache, D | 1 |
| Meredith, D | 1 |
| Anderson, M | 1 |
| Fowden, AL | 1 |
| Limesand, SW | 1 |
| Forhead, AJ | 1 |
| Riis, AL | 2 |
| Gravholt, CH | 1 |
| Djurhuus, CB | 1 |
| Nørrelund, H | 1 |
| Jørgensen, JO | 2 |
| Weeke, J | 2 |
| Møller, N | 2 |
| Hansen, TK | 1 |
| UTIGER, RD | 1 |
| Bhatt, P | 1 |
| Makwana, D | 1 |
| Santani, D | 1 |
| Goyal, R | 1 |
| Kolodin, VA | 1 |
| Gasilin, VS | 1 |
| Baranov, VA | 1 |
| Antonov, IuS | 1 |
| Dokuchaeva, EA | 1 |
| Chapa, AM | 1 |
| Fernandez, JM | 1 |
| Thompson, DL | 1 |
| Tempelman, RJ | 1 |
| Berrio, LF | 1 |
| Croom, WJ | 1 |
| Hagler, WM | 1 |
| Torrance, CJ | 1 |
| Devente, JE | 1 |
| Jones, JP | 1 |
| Dohm, GL | 1 |
| Bakker, SJ | 1 |
| ter Maaten, JC | 1 |
| Popp-Snijders, C | 1 |
| Heine, RJ | 1 |
| Gans, RO | 1 |
| Lifshits, GI | 1 |
| Nikolaev, KIu | 1 |
| Oteva, EA | 1 |
| Nikolaeva, AA | 1 |
| Burgess, JA | 1 |
| Smith, BR | 1 |
| Merimee, TJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Corneal Tomographic Analysis Among Patients With Thyroid Gland Dysfunction.[NCT04433936] | 100 participants (Actual) | Observational | 2018-02-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for triiodothyronine and Hyperinsulinism
| Article | Year |
|---|---|
Hyperthyroidism is associated with suppressed circulating ghrelin levels.
Topics: Adult; Body Composition; Energy Metabolism; Fasting; Female; Ghrelin; Glucose Clamp Technique; Human | 2003 |
Triiodothyronine: a link between the insulin resistance syndrome and blood pressure?
Topics: Adolescent; Adult; Blood Glucose; Blood Pressure; Body Mass Index; Cross-Sectional Studies; Female; | 1999 |
12 other studies available for triiodothyronine and Hyperinsulinism
| Article | Year |
|---|---|
Hyperinsulinemia and thyroid peroxidase antibody in Chinese patients with papillary thyroid cancer.
Topics: Adult; Asian People; Autoantibodies; China; Female; Humans; Hyperinsulinism; Male; Middle Aged; Retr | 2019 |
Gestational dexamethasone alters fetal neuroendocrine axis.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dexamethasone; Endocrine Disruptors; Female; Fetal Dev | 2016 |
Serum insulin in pathogenesis and treatment of osteoarthritis.
Topics: Adipokines; Cartilage; Cell Differentiation; Cell Proliferation; Chondrocytes; Disease Progression; | 2017 |
Hypothyroidism in utero stimulates pancreatic beta cell proliferation and hyperinsulinaemia in the ovine fetus during late gestation.
Topics: Animals; Cell Proliferation; Cells, Cultured; Female; Fetal Diseases; Hyperinsulinism; Hypothyroidis | 2017 |
Elevated regional lipolysis in hyperthyroidism.
Topics: Abdomen; Adipose Tissue; Adult; Antithyroid Agents; Blood Flow Velocity; Energy Metabolism; Fatty Ac | 2002 |
RADIOIMMUNOASSAY OF HUMAN PLASMA THYROTROPIN.
Topics: Antigen-Antibody Reactions; Chromatography; Chromatography, Gel; Drug Therapy; Electrophoresis; Huma | 1965 |
Comparative effectiveness of carvedilol and propranolol on glycemic control and insulin resistance associated with L-thyroxin-induced hyperthyroidism--an experimental study.
Topics: Adrenergic beta-Antagonists; Animals; Appetite; Blood Glucose; Blood Pressure; Body Mass Index; Body | 2007 |
[Role of excessive body weight and hormonal changes in the development of the main types of hyperlipoproteinemia].
Topics: Adrenocortical Hyperfunction; Adult; Growth Hormone; Humans; Hydrocortisone; Hyperinsulinism; Hyperl | 1984 |
Endocrine and metabolic response to muscarinic stimulation and inhibition in the ruminant: effects of slaframine.
Topics: Alkaloids; Animals; Blood Glucose; Endocrine Glands; Fatty Acids, Nonesterified; Female; Goat Diseas | 1995 |
Effects of thyroid hormone on GLUT4 glucose transporter gene expression and NIDDM in rats.
Topics: Animals; Diabetes Mellitus, Type 2; Gene Expression; Glucose Transporter Type 4; Hindlimb; Hyperinsu | 1997 |
[Ischemic heart disease and metabolic syndrome X (family study)].
Topics: Adolescent; Adult; Apolipoproteins B; Arteriosclerosis; Autonomic Nervous System Diseases; Body Weig | 2000 |
Growth hormone in thyrotoxicosis: effect of insulin-induced hypoglycemia.
Topics: Adult; Aged; Blood Glucose; Female; Growth Hormone; Humans; Hyperinsulinism; Hyperthyroidism; Hypogl | 1966 |