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triiodothyronine and Hormone-Dependent Neoplasms

triiodothyronine has been researched along with Hormone-Dependent Neoplasms in 11 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"ZR-75-1, a human breast cancer cell line, has been grown in hormone-supplemented medium without serum."1.26Growth of a human breast cancer cell line in serum-free hormone-supplemented medium. ( Allegra, JC; Lippman, ME, 1978)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's3 (27.27)18.2507
2000's1 (9.09)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shinderman-Maman, E1
Cohen, K1
Weingarten, C1
Nabriski, D1
Twito, O1
Baraf, L1
Hercbergs, A1
Davis, PJ1
Werner, H1
Ellis, M1
Ashur-Fabian, O1
Sibilio, A1
Ambrosio, R1
Bonelli, C1
De Stefano, MA1
Torre, V1
Dentice, M1
Salvatore, D1
García-Solís, P1
Aceves, C1
Gupta, MK1
Chiang, T1
Deodhar, SD1
Natoli, C1
Sica, G1
Natoli, V1
Scambia, G1
Iacobelli, S1
Goodman, AD1
Hoekstra, SJ1
Marsh, PS1
Quirin-Stricker, C1
Nappey, V1
Simoni, P1
Toussaint, JL1
Schmitt, M1
Roy, G1
Nakatani, T1
Goto, T1
Fujimoto, N2
Ito, A2
Burke, RE1
McGuire, WL1
Allegra, JC1
Lippman, ME1
Watanabe, H1

Reviews

1 review available for triiodothyronine and Hormone-Dependent Neoplasms

ArticleYear
Deiodination in cancer growth: the role of type III deiodinase.
    Minerva endocrinologica, 2012, Volume: 37, Issue:4

    Topics: Cell Division; Cell Transformation, Neoplastic; Enzyme Activation; Enzyme Induction; Gene Expression

2012

Other Studies

10 other studies available for triiodothyronine and Hormone-Dependent Neoplasms

ArticleYear
The thyroid hormone-αvβ3 integrin axis in ovarian cancer: regulation of gene transcription and MAPK-dependent proliferation.
    Oncogene, 2016, Apr-14, Volume: 35, Issue:15

    Topics: Antibodies, Neutralizing; Cell Division; Cell Line, Tumor; Culture Media; Enzyme Activation; Extrace

2016
5'Deiodinase in two breast cancer cell lines: effect of triiodothyronine, isoproterenol and retinoids.
    Molecular and cellular endocrinology, 2003, Mar-28, Volume: 201, Issue:1-2

    Topics: Adrenergic beta-Agonists; Breast Neoplasms; Cell Differentiation; DNA Primers; Female; Humans; Iodid

2003
Specific triiodothyronine binding by tumor cells and spleen cells in a thyroid hormone dependent mouse tumor system.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:7

    Topics: Animals; Binding, Competitive; Cell Nucleus; Female; Fibrosarcoma; Mice; Mice, Inbred C57BL; Mitocho

1981
Growth inhibitory effects of thyroid hormones on androgen-dependent mammary tumor cells.
    Journal of steroid biochemistry, 1981, Volume: 15

    Topics: Androgens; Animals; Cell Division; Cells, Cultured; Female; Mammary Neoplasms, Experimental; Mice; N

1981
Effects of hypothyroidism on the induction and growth of mammary cancer induced by 7,12-dimethylbenz(a)anthracene in the rat.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Female; Hypothyroidism; Mammary Neoplasms, E

1980
Trans-activation by thyroid hormone receptors of the 5' flanking region of the human ChAT gene.
    Brain research. Molecular brain research, 1994, Volume: 23, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Breast Neoplasms; Cells, Cultured; Chlorocebus aethiops

1994
Effect of 17 beta-estradiol, retinoic acid and tamoxifen upon primary and transplanted thyroid tumor in B6C3F1 mice fed an iodine deficient diet.
    Hiroshima journal of medical sciences, 1997, Volume: 46, Issue:4

    Topics: Animals; Estradiol; Female; Iodine; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Trans

1997
Nuclear thyroid hormone receptors in a human breast cancer cell line.
    Cancer research, 1978, Volume: 38, Issue:11 Pt 1

    Topics: Binding, Competitive; Breast Neoplasms; Cell Division; Cell Line; Cell Nucleus; Humans; Kinetics; Ne

1978
Growth of a human breast cancer cell line in serum-free hormone-supplemented medium.
    Cancer research, 1978, Volume: 38, Issue:11 Pt 1

    Topics: Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Division; Cell Line; Cell Survival;

1978
Direct up-regulation of estrogen receptor by triiodothyronine in rat pituitary tumor MtT/F84.
    Endocrinologia japonica, 1991, Volume: 38, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Estradiol; Estrogens; Growth Hormone; In Vitro Techniques

1991