triiodothyronine has been researched along with Heart Diseases in 50 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Little is known about the impact of low triiodothyronine (T3) levels on mortality in end-stage renal disease (ESRD) patients starting hemodialysis (HD) and whether this impact is mediated by malnutrition, inflammation, or cardiac dysfunction." | 7.79 | The impact of low triiodothyronine levels on mortality is mediated by malnutrition and cardiac dysfunction in incident hemodialysis patients. ( Doh, FM; Han, JH; Han, JS; Han, SH; Kang, SW; Kim, CH; Kim, EJ; Koo, HM; Lee, MJ; Oh, HJ; Yoo, TH, 2013) |
| "Amiodarone-induced thyrotoxicosis is a life-threatening condition." | 7.74 | Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007) |
| "Amiodarone induces in patients "low T3-syndrome" characterized by normal T4." | 7.66 | [Amiodarone-induce "low T3-syndrome" (author's transl)]. ( Beckers, C; Jonckheer, MH; Smekens, L, 1978) |
| "In some patients with hypothyroidism, symptoms of ill health persist despite thyroxine treatment." | 4.81 | Dissatisfaction with thyroxine therapy - could the patients be right? ( Walsh, JP, 2002) |
| "Little is known about the impact of low triiodothyronine (T3) levels on mortality in end-stage renal disease (ESRD) patients starting hemodialysis (HD) and whether this impact is mediated by malnutrition, inflammation, or cardiac dysfunction." | 3.79 | The impact of low triiodothyronine levels on mortality is mediated by malnutrition and cardiac dysfunction in incident hemodialysis patients. ( Doh, FM; Han, JH; Han, JS; Han, SH; Kang, SW; Kim, CH; Kim, EJ; Koo, HM; Lee, MJ; Oh, HJ; Yoo, TH, 2013) |
| "Recent data suggest that low triiodothyronine (T3) syndrome may contribute to the pathophysiology of cardiac diseases." | 3.75 | [Low T3 syndrome and left ventricular diastolic function]. ( Bianchi, M; Bindi, M; Cassetti, G; Castiglioni, M; Pinelli, M, 2009) |
| "Amiodarone-induced thyrotoxicosis is a life-threatening condition." | 3.74 | Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007) |
| "Amiodarone induces in patients "low T3-syndrome" characterized by normal T4." | 3.66 | [Amiodarone-induce "low T3-syndrome" (author's transl)]. ( Beckers, C; Jonckheer, MH; Smekens, L, 1978) |
| "Low-T3 syndrome is a strong predictor of death in cardiac patients and might be directly implicated in the poor prognosis of cardiac patients." | 2.71 | Low-T3 syndrome: a strong prognostic predictor of death in patients with heart disease. ( Donato, L; Iervasi, G; L'Abbate, A; Landi, P; Pingitore, A; Raciti, M; Ripoli, A; Scarlattini, M, 2003) |
| "Patients with hypothyroidism are at a higher risk for coronary vascular disease." | 1.35 | Thyroid hormone analog 3,5-diiodothyropropionic acid promotes healthy vasculature in the adult myocardium independent of thyroid effects on cardiac function. ( Gerdes, AM; Liu, Y; Redetzke, RA; Sherer, BA; Wang, D, 2009) |
| "Lycopus extract was tested in thyroxine treated hyperthyroid rats (0." | 1.33 | Extract of Lycopus europaeus L. reduces cardiac signs of hyperthyroidism in rats. ( Baumgartner, A; Biller, A; Hegger, M; Korte, B; Vonhoff, C; Winterhoff, H, 2006) |
| "Subclinical hyperthyroidism has been associated with harmful cardiac effects, but its treatment remains controversial." | 1.32 | The effects of early antithyroid therapy for endogenous subclinical hyperthyroidism in clinical and heart abnormalities. ( Garbeline, B; Romaldini, JH; Sgarbi, JA; Villaça, FG; Villar, HE, 2003) |
| "In contrast, T3-induced cardiac hypertrophy was not accompanied by changes in Gi alpha-mRNA expression." | 1.28 | Isoprenaline-induced increase in mRNA levels of inhibitory G-protein alpha-subunits in rat heart. ( Eschenhagen, T; Mende, U; Nose, M; Schmitz, W; Scholz, H; Warnholtz, A; Wüstel, JM, 1991) |
| "Hyperthyroidism was a more frequent (9." | 1.27 | Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy. ( Aghini-Lombardi, F; Aronin, N; Fay, M; Haffajee, C; Lenziardi, M; Macchia, E; Martino, E; Pacchiarotti, A; Rajatanavin, R; Safran, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (48.00) | 18.7374 |
| 1990's | 5 (10.00) | 18.2507 |
| 2000's | 18 (36.00) | 29.6817 |
| 2010's | 3 (6.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chattergoon, NN | 1 |
| Koo, HM | 1 |
| Kim, CH | 1 |
| Doh, FM | 1 |
| Lee, MJ | 1 |
| Kim, EJ | 1 |
| Han, JH | 1 |
| Han, JS | 1 |
| Oh, HJ | 1 |
| Han, SH | 1 |
| Yoo, TH | 1 |
| Kang, SW | 1 |
| François, M | 1 |
| Delemer, B | 1 |
| Liu, Y | 1 |
| Wang, D | 1 |
| Redetzke, RA | 1 |
| Sherer, BA | 1 |
| Gerdes, AM | 1 |
| Cassetti, G | 1 |
| Pinelli, M | 1 |
| Bindi, M | 1 |
| Bianchi, M | 1 |
| Castiglioni, M | 1 |
| García, JL | 1 |
| Etayo, BZ | 1 |
| Calvo, JI | 1 |
| Mete, O | 1 |
| Asa, SL | 1 |
| Walsh, JP | 1 |
| Iervasi, G | 1 |
| Pingitore, A | 1 |
| Landi, P | 1 |
| Raciti, M | 1 |
| Ripoli, A | 1 |
| Scarlattini, M | 1 |
| L'Abbate, A | 1 |
| Donato, L | 1 |
| Sauviat, MP | 1 |
| Pages, N | 1 |
| Sgarbi, JA | 1 |
| Villaça, FG | 1 |
| Garbeline, B | 1 |
| Villar, HE | 1 |
| Romaldini, JH | 1 |
| GRIBOFF, SI | 1 |
| CATZ, B | 1 |
| MINTZ, DO | 1 |
| BERENYI, MR | 1 |
| ROSENBERG, IN | 1 |
| KATZ, KH | 1 |
| Vonhoff, C | 1 |
| Baumgartner, A | 1 |
| Hegger, M | 1 |
| Korte, B | 1 |
| Biller, A | 1 |
| Winterhoff, H | 1 |
| Olson, RD | 1 |
| Gambliel, HA | 1 |
| Vestal, RE | 1 |
| Shadle, SE | 1 |
| Charlier, HA | 1 |
| Cusack, BJ | 1 |
| Trivieri, MG | 1 |
| Oudit, GY | 1 |
| Sah, R | 1 |
| Kerfant, BG | 1 |
| Sun, H | 1 |
| Gramolini, AO | 1 |
| Pan, Y | 1 |
| Wickenden, AD | 1 |
| Croteau, W | 1 |
| Morreale de Escobar, G | 1 |
| Pekhletski, R | 1 |
| St Germain, D | 1 |
| Maclennan, DH | 1 |
| Backx, PH | 1 |
| Berti, P | 1 |
| Materazzi, G | 1 |
| Bogazzi, F | 1 |
| Ambrosini, CE | 1 |
| Martino, E | 2 |
| Miccoli, P | 1 |
| van Rooij, E | 1 |
| Sutherland, LB | 1 |
| Qi, X | 1 |
| Richardson, JA | 1 |
| Hill, J | 1 |
| Olson, EN | 1 |
| Safran, M | 1 |
| Aghini-Lombardi, F | 1 |
| Rajatanavin, R | 1 |
| Lenziardi, M | 1 |
| Fay, M | 1 |
| Pacchiarotti, A | 1 |
| Aronin, N | 1 |
| Macchia, E | 1 |
| Haffajee, C | 1 |
| Límanová, Z | 1 |
| Simonová, J | 1 |
| Felt, V | 2 |
| Cenková, V | 2 |
| Nedvídková, J | 2 |
| Davies, PH | 1 |
| Black, EG | 1 |
| Sheppard, MC | 1 |
| Franklyn, JA | 1 |
| Aoyagi, S | 1 |
| Shimada, S | 1 |
| Kosuga, K | 1 |
| Ohishi, K | 1 |
| Drvota, V | 1 |
| Yeo, PP | 1 |
| Loh, KC | 1 |
| Fadel, BM | 1 |
| Ellahham, S | 1 |
| Ringel, MD | 1 |
| Lindsay, J | 1 |
| Wartofsky, L | 2 |
| Burman, KD | 2 |
| Pujol, P | 1 |
| De Boisvilliers, F | 1 |
| Bringer, J | 1 |
| Jaffiol, C | 1 |
| Klein, I | 3 |
| Ojamaa, K | 2 |
| Stathatos, N | 1 |
| Levetan, C | 1 |
| Chopra, IJ | 1 |
| Solomon, DH | 1 |
| Hepner, GW | 1 |
| Morgenstein, AA | 1 |
| Gavin, LA | 1 |
| Rosenthal, M | 1 |
| Cavalieri, RR | 1 |
| Jonckheer, MH | 1 |
| Smekens, L | 1 |
| Beckers, C | 1 |
| Thomas, J | 1 |
| Mills, KB | 1 |
| Grisham, DW | 1 |
| Rivlin, RS | 1 |
| Eschenhagen, T | 1 |
| Mende, U | 1 |
| Nose, M | 1 |
| Schmitz, W | 1 |
| Scholz, H | 1 |
| Warnholtz, A | 1 |
| Wüstel, JM | 1 |
| Barbee, RW | 1 |
| Shepherd, RE | 1 |
| Burns, AH | 1 |
| Tahiliani, AG | 2 |
| McNeill, JH | 2 |
| Csako, G | 1 |
| Zweig, MH | 1 |
| Benson, C | 1 |
| Ruddel, M | 1 |
| Dyer, C | 1 |
| Casey, AE | 1 |
| Downey, EL | 1 |
| Copeland, H | 1 |
| Wilks, MN | 1 |
| Földes, J | 1 |
| Lengyel, Z | 1 |
| Gesztesi, E | 1 |
| Takács, I | 1 |
| Levey, GS | 1 |
| Epstein, SE | 1 |
| Blum, M | 1 |
| Wilson, IC | 1 |
| Shafer, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation in Both Skeletal Muscle and Adipose Tissue[NCT01911091] | 56 participants (Anticipated) | Interventional | 2013-07-31 | Active, not recruiting | |||
| Effect of Levothyroxine on Serum Adiponectin, Insulin Resistance and Cardiovascular Risk in Patients With Hypothyroidism[NCT02467244] | 120 participants (Actual) | Observational | 2017-02-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for triiodothyronine and Heart Diseases
| Article | Year |
|---|---|
Thyroid hormone signaling and consequences for cardiac development.
Topics: Animals; Cardiovascular Diseases; Cell Proliferation; Female; Fetal Development; Fetal Heart; Heart; | 2019 |
[What's new in the couple thyroid and heart in 2008?].
Topics: Animals; Heart; Heart Diseases; Humans; Mice; MicroRNAs; Models, Animal; Myocardial Contraction; Rec | 2008 |
Dissatisfaction with thyroxine therapy - could the patients be right?
Topics: Bone Diseases; Drug Therapy, Combination; Heart Diseases; Humans; Hypothyroidism; Patient Satisfacti | 2002 |
[Cardiotoxicity of lindane, a gamma isomer of hexachlorocyclohexane].
Topics: Animals; Calcium Signaling; Cats; Cell Communication; Chloride Channels; Electrocardiography; Heart; | 2002 |
Subclinical thyrotoxicosis.
Topics: Atrial Fibrillation; Biomarkers; Bone and Bones; Bone Density; Bone Resorption; Diagnosis, Different | 1998 |
Hyperthyroid heart disease.
Topics: Atrial Fibrillation; Heart; Heart Diseases; Heart Failure; Humans; Hyperthyroidism; Myocardial Contr | 2000 |
Thyroid hormone-targeting the heart.
Topics: Animals; Cardiovascular System; Heart; Heart Diseases; Humans; Myocardial Contraction; Receptors, Th | 2001 |
Thyroid hormone and the cardiovascular system.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Heart; Heart Diseases | 2001 |
The controversy of the treatment of critically ill patients with thyroid hormone.
Topics: Animals; Critical Care; Critical Illness; Heart Diseases; Humans; Infections; Respiration; Shock; Th | 2001 |
Thyroid hormone and the cardiovascular system.
Topics: Heart; Heart Diseases; Hemodynamics; Humans; Myocardial Contraction; Thyroid Diseases; Thyroxine; Tr | 1990 |
Diabetes-induced abnormalities in the myocardium.
Topics: Adenosine Triphosphatases; Animals; Blood Glucose; Calcium; Carbohydrate Metabolism; Cardiomyopathie | 1986 |
Myxedema coma.
Topics: Adrenal Glands; Cachexia; Central Nervous System; Coma; Heart Diseases; Humans; Hypoglycemia; Hypona | 1972 |
2 trials available for triiodothyronine and Heart Diseases
| Article | Year |
|---|---|
Low-T3 syndrome: a strong prognostic predictor of death in patients with heart disease.
Topics: Aged; Female; Follow-Up Studies; Heart Diseases; Humans; Hyperlipidemias; Logistic Models; Male; Mid | 2003 |
Effects of thyrotropin suppression with tri-lodothyroacetic acid on radionuclide cardiovascular parameters.
Topics: Female; Goiter; Heart Diseases; Humans; Male; Middle Aged; Radionuclide Imaging; Thyrotropin; Triiod | 2000 |
36 other studies available for triiodothyronine and Heart Diseases
| Article | Year |
|---|---|
The impact of low triiodothyronine levels on mortality is mediated by malnutrition and cardiac dysfunction in incident hemodialysis patients.
Topics: Adult; Aged; Echocardiography; Female; Heart Diseases; Humans; Incidence; Inflammation; Kaplan-Meier | 2013 |
Thyroid hormone analog 3,5-diiodothyropropionic acid promotes healthy vasculature in the adult myocardium independent of thyroid effects on cardiac function.
Topics: Angiogenesis Inducing Agents; Animals; Body Temperature; Coronary Vessels; Diiodothyronines; Disease | 2009 |
[Low T3 syndrome and left ventricular diastolic function].
Topics: Aged; Biomarkers; Case-Control Studies; Diastole; Echocardiography, Doppler; Euthyroid Sick Syndrome | 2009 |
[Blockade of the renin-angiotensin-aldosterone system in Graves' disease].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Cardiac Output; F | 2009 |
Images in endocrine pathology: thyrotoxicosis associated with destructive thyroiditis.
Topics: Amiodarone; Heart Diseases; Humans; Male; Middle Aged; Thyroidectomy; Thyroiditis; Thyrotoxicosis; T | 2012 |
The effects of early antithyroid therapy for endogenous subclinical hyperthyroidism in clinical and heart abnormalities.
Topics: Adolescent; Adult; Aged; Antithyroid Agents; Arrhythmias, Cardiac; Diastole; Echocardiography; Elect | 2003 |
Myxedema heart: rapid electrocardiographic response to L-triiodothyronine.
Topics: Electrocardiography; Heart; Heart Diseases; Humans; Myxedema; Triiodothyronine | 1963 |
THYROID DIAGNOSTIC PROBLEMS.
Topics: Asthma; Deficiency Diseases; Female; Geriatrics; Goiter; Heart Diseases; Humans; Hyperthyroidism; Hy | 1964 |
D-Tri-iodothyronine treatment of hypercholesterolemia in patients with heart disease.
Topics: Cholesterol; Coronary Disease; Diuretics; Heart Diseases; Humans; Hypercholesterolemia; Triiodothyro | 1962 |
Extract of Lycopus europaeus L. reduces cardiac signs of hyperthyroidism in rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Body Temperature; Body Weight; Eatin | 2006 |
Doxorubicin cardiac dysfunction: effects on calcium regulatory proteins, sarcoplasmic reticulum, and triiodothyronine.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Blotting, Western; Calcium; Calcium Ch | 2005 |
Cardiac-specific elevations in thyroid hormone enhance contractility and prevent pressure overload-induced cardiac dysfunction.
Topics: Animals; Blood Pressure; Calcium Signaling; Calcium-Transporting ATPases; Gene Expression Regulation | 2006 |
Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study.
Topics: Aged; Amiodarone; Anesthesia, Local; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonomic Nerve B | 2007 |
Control of stress-dependent cardiac growth and gene expression by a microRNA.
Topics: Animals; Cardiac Myosins; Cardiomegaly; Fibrosis; Gene Deletion; Gene Expression Regulation; Heart; | 2007 |
Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy.
Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Goiter; Heart Diseases; Humans; Hyperthyroidism; Hypot | 1984 |
[Determination of the levels of thyroxine, triiodothyronine and reverse triiodothyronine in heart disease].
Topics: Female; Heart Diseases; Humans; Male; Middle Aged; Thyroxine; Triiodothyronine; Triiodothyronine, Re | 1983 |
Changes of triiodothyronine and thyroxine in patients with thyrocardiac disease and their relationship to systolic time intervals.
Topics: Achilles Tendon; Adult; Aged; Coronary Disease; Female; Heart Diseases; Humans; Hyperthyroidism; Mal | 1982 |
[Disturbed thyroxine and triiodothyronine metabolism in patients with heart involvement in thyrotoxicosis].
Topics: Adolescent; Adult; Aged; Female; Heart Diseases; Humans; Hyperthyroidism; Male; Middle Aged; Thyroxi | 1980 |
Relation between serum interleukin-6 and thyroid hormone concentrations in 270 hospital in-patients with non-thyroidal illness.
Topics: Euthyroid Sick Syndromes; Heart Diseases; Humans; Interleukin-6; Kidney Diseases; Liver Diseases; Th | 1996 |
[Thyroid-pituitary response to cardiopulmonary bypass].
Topics: Adult; Cardiopulmonary Bypass; Female; Heart Diseases; Humans; Male; Middle Aged; Thyrotropin; Thyro | 1988 |
Downregulation of thyroid hormone receptor subtype mRNA levels by retinoic acid in cultured cardiomyocytes.
Topics: Diiodothyronines; DNA Probes; Down-Regulation; Heart Diseases; Humans; Myocardium; Propionates; Rece | 1998 |
Misleadingly low free thyroxine index and usefulness of reverse triiodothyronine measurement in nonthyroidal illnesses.
Topics: Adult; Aged; Diagnosis, Differential; Diagnostic Errors; Evaluation Studies as Topic; Heart Diseases | 1979 |
The diagnostic dilemma of isolated hyperthyroxinemia in acute illness.
Topics: Acute Disease; Aged; Asthma; Carcinoma, Bronchogenic; Female; Heart Diseases; Humans; Infections; Li | 1979 |
[Amiodarone-induce "low T3-syndrome" (author's transl)].
Topics: Amiodarone; Benzofurans; Heart Diseases; Humans; Syndrome; Triiodothyronine | 1978 |
Primary myxedema heart disease.
Topics: Aged; Electrocardiography; Heart Diseases; Humans; Male; Myxedema; Triiodothyronine | 1978 |
Therapy of obesity with hormones.
Topics: Adult; Animals; Child; Chorionic Gonadotropin; Growth Hormone; Heart Diseases; Humans; Injections, I | 1975 |
Isoprenaline-induced increase in mRNA levels of inhibitory G-protein alpha-subunits in rat heart.
Topics: Animals; Autoradiography; Blotting, Northern; Cardiomegaly; GTP-Binding Proteins; Heart Diseases; He | 1991 |
T3 treatment does not prevent myocardial dysfunction in chronically diabetic rats.
Topics: Animals; Caprylates; Cytochrome c Group; Diabetes Mellitus, Experimental; Half-Life; Heart Diseases; | 1988 |
On the albumin-dependence of measurements of free thyroxin. II. Patients with non-thyroidal illness.
Topics: Diagnostic Errors; Dialysis; Heart Diseases; Humans; Neoplasms; Radioimmunoassay; Serum Albumin; Sta | 1987 |
Effects of triiodothyronine and carnitine therapy on myocardial dysfunction in diabetic rats.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Female; Heart Diseases; Myocardial Contraction; | 1986 |
The Gee case: the BBC continues alone.
Topics: Female; Heart Diseases; Humans; Jurisprudence; Television; Triiodothyronine; United Kingdom | 1985 |
Lactic dehydrogenase, leucine aminopeptidase, alpha globulin, and azotemia in circulatory stress.
Topics: Alkaline Phosphatase; Alpha-Globulins; Aspartate Aminotransferases; Autoanalysis; Blood Urea Nitroge | 1974 |
[The determination of the "free thyroxine" index in internal diseases].
Topics: Diagnosis, Differential; Erythrocytes; Heart Diseases; Heart Failure; Humans; Hyperthyroidism; Hypot | 1967 |
Myocardial adenyl cyclase: activation by thyroid hormones and evidence for two adenyl cyclase systems.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cats; Cyclic AMP; Enzymes; | 1969 |
Caution in thyroid therapy.
Topics: Age Factors; Aged; Depression; Heart Diseases; Humans; Hypothyroidism; Middle Aged; Myxedema; Triiod | 1970 |
Caution in thyroid therapy.
Topics: Age Factors; Aged; Depression; Heart Diseases; Humans; Hypothyroidism; Middle Aged; Myxedema; Triiod | 1970 |