Page last updated: 2024-11-08

triiodothyronine and Heart Arrest

triiodothyronine has been researched along with Heart Arrest in 12 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Heart Arrest: Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.

Research Excerpts

ExcerptRelevanceReference
" In a previous investigation, post-resuscitation infusion of levothyroxine sodium (L-T4) to normalize serum 3,5,3'-triiodothyronine (T3) concentrations was associated with significant reduction of neurologic deficit caused by severe global cerebral ischemia."3.69Acute administration of T3 or rT3 failed to improve outcome following resuscitation from cardiac arrest in dogs. ( D'Alecy, LG; Mayor, GH; Nachreiner, RF; Whitesall, SE; Zwemer, CF, 1996)
"Fifty patients with cardiac arrest induced by ACS and 31 patients with acute myocardial infarction (AMI) who did not require cardioversion or cardiopulmonary resuscitation were enrolled in the study, as were 40 healthy volunteers."2.71Clinical investigation: thyroid function test abnormalities in cardiac arrest associated with acute coronary syndrome. ( Ariturk, Z; Iltumur, K; Olmez, G; Taskesen, T; Toprak, N, 2005)
"Thyroid function was evaluated in cardiac arrest (CA), a condition associated with marked activation of the pituitary-adrenal axis."1.27Hypothyroxinemia in cardiac arrest. ( Chopra, IJ; Murphy, JE; Premachandra, BN; Wortsman, J, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's4 (33.33)18.2507
2000's3 (25.00)29.6817
2010's2 (16.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Weil, BR1
Allen, SE1
Barbaccia, T1
Wong, K1
Beaver, AM1
Slabinski, EA1
Mellott, JG1
Taylor Dickinson, PC1
Mousa, SA1
Ahmad, S1
Giannopoulou, A1
Owen, P1
Kalhan, A1
Kuryłowicz, A1
Niewiński, G1
Kański, A1
Derlatka, P1
Czajkowski, K1
Bednarczuk, T1
Ambroziak, U1
Jao, YT1
Chen, Y1
Lee, WH1
Tai, FT1
Iltumur, K1
Olmez, G1
Ariturk, Z1
Taskesen, T1
Toprak, N1
Jeevanandam, V1
Todd, B1
Hellman, S1
Eldridge, C1
McClurken, J1
Addonizio, VP1
Whitesall, SE1
Mayor, GH2
Nachreiner, RF1
Zwemer, CF1
D'Alecy, LG2
Longstreth, WT1
Manowitz, NR1
DeGroot, LJ1
Siscovick, DS1
Copass, MK1
Weinmann, S1
Cobb, LA1
Roels, L1
Pirenne, J1
Delooz, H1
Lauwers, P1
Vandermeersch, E1
Wortsman, J1
Premachandra, BN1
Chopra, IJ1
Murphy, JE1
Siess, M1

Trials

1 trial available for triiodothyronine and Heart Arrest

ArticleYear
Clinical investigation: thyroid function test abnormalities in cardiac arrest associated with acute coronary syndrome.
    Critical care (London, England), 2005, Volume: 9, Issue:4

    Topics: Cardiopulmonary Resuscitation; Coronary Disease; Creatine Kinase, MB Form; Electric Countershock; Eu

2005

Other Studies

11 other studies available for triiodothyronine and Heart Arrest

ArticleYear
Preclinical evaluation of triiodothyronine nanoparticles as a novel therapeutic intervention for resuscitation from cardiac arrest.
    Resuscitation, 2023, Volume: 186

    Topics: Animals; Biomarkers; Cardiopulmonary Resuscitation; Heart Arrest; Swine; Thorax; Triiodothyronine

2023
Polyglandular endocrine emergency: lessons from a patient, which a book cannot teach.
    BMJ case reports, 2018, Nov-08, Volume: 2018

    Topics: Addison Disease; Adrenergic beta-Agonists; Adult; Anti-Inflammatory Agents; Celiac Disease; Diabetes

2018
Severe gestational hyperthyroidism complicated by cardiac arrest - a case report.
    Ginekologia polska, 2017, Volume: 88, Issue:1

    Topics: Abortion, Therapeutic; Adult; Antithyroid Agents; Cardiopulmonary Resuscitation; Female; Heart Arres

2017
Thyroid storm and ventricular tachycardia.
    Southern medical journal, 2004, Volume: 97, Issue:6

    Topics: Adult; Cardiopulmonary Resuscitation; Electrocardiography; Fatal Outcome; Female; Heart Arrest; Huma

2004
Use of triiodothyronine replacement therapy to reverse donor myocardial dysfunction: creating a larger donor pool.
    Transplantation proceedings, 1993, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Blood Pressure; Brain Death; Child; Dopamine; Female; Heart; Heart Arrest; Heart

1993
Acute administration of T3 or rT3 failed to improve outcome following resuscitation from cardiac arrest in dogs.
    Resuscitation, 1996, Volume: 33, Issue:1

    Topics: Animals; Brain Ischemia; Dogs; Heart Arrest; Male; Neurologic Examination; Radioimmunoassay; Resusci

1996
Plasma thyroid hormone profiles immediately following out-of-hospital cardiac arrest.
    Thyroid : official journal of the American Thyroid Association, 1996, Volume: 6, Issue:6

    Topics: Aged; Female; Heart Arrest; Humans; Male; Middle Aged; Retrospective Studies; Thyroid Hormones; Thyr

1996
Thyroid hormone in neural rescue.
    Thyroid : official journal of the American Thyroid Association, 1997, Volume: 7, Issue:1

    Topics: Animals; Carbon Dioxide; Cardiac Output; Cardiopulmonary Resuscitation; Dogs; Heart Arrest; Hypothyr

1997
Effect of triiodothyronine replacement therapy on maintenance characteristics and organ availability in hemodynamically unstable donors.
    Transplantation proceedings, 2000, Volume: 32, Issue:7

    Topics: Adolescent; Adult; Aged; Brain Death; Cadaver; Cause of Death; Dobutamine; Female; Heart Arrest; Hem

2000
Hypothyroxinemia in cardiac arrest.
    Archives of internal medicine, 1987, Volume: 147, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Female; Heart Arrest; Humans; Male; Middle Aged; Thyroglobulin; Thyr

1987
Effects on efficiency and consumption of 14C-glucose and 14C-hexanoate in arrested and beating atria of guinea pigs.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2

    Topics: Animals; Biomechanical Phenomena; Caproates; Carbon Isotopes; Glucose; Guinea Pigs; Heart Arrest; He

1968